keyword
https://read.qxmd.com/read/38648371/responses-to-lead-stress-in-scrophularia-striata-insights-into-antioxidative-defence-mechanisms-and-changes-in-flavonoids-profile
#21
JOURNAL ARTICLE
Reyhaneh Danaeipour, Mohsen Sharifi, Azam Noori
Lead (Pb) induces oxidative stress in plants, which results in different responses, including the production of antioxidants and changes in the profile of secondary metabolites. In this study, the responses of Scrophularia striata exposed to 250mgL-1 Pb (NO3 )2 in a hydroponic environment were determined. Growth parameters, oxidative and antioxidative responses, redox status, and the concentration of Pb were analysed in roots and shoots. Malondialdehyde and hydrogen peroxide (H2 O2 ) levels in the roots were significantly increased and reached their highest value at 72h after Pb treatment...
April 2024: Functional Plant Biology: FPB
https://read.qxmd.com/read/38648023/perceived-stress-blood-biomarkers-and-cognitive-functioning-in-older-adults
#22
JOURNAL ARTICLE
Pankaja Desai, Ted K S Ng, Kristin R Krueger, Robert S Wilson, Denis A Evans, Kumar B Rajan
INTRODUCTION: There is a substantial gap in knowledge regarding how perceived stress may influence the relationship between serum-measured biomarkers for Alzheimer's disease and cognitive decline. METHODS: This study consists of 1,118 older adult participants from the Chicago Health and Aging Project (CHAP) (60% Black participants and 63% female participants). Linear mixed effects regression models were conducted to examine the role of perceived stress in the association between three blood biomarkers: total tau (t-tau), glial fibrillary acid protein (GFAP), and neurofilament light chain (NfL) on global cognitive decline...
April 16, 2024: Psychosomatic Medicine
https://read.qxmd.com/read/38648006/comprehensive-assessment-of-the-microbial-community-structure-in-a-typical-lead-zinc-mine-soil
#23
JOURNAL ARTICLE
Taotao Zeng, Haichao Sha, Qingqing Xie, Yue Lu, Haidu Nong, Liangqin Wang, Lin Tang
Understanding the microbial community structure in soil contaminated with heavy metals (HMs) is a precondition to conduct bioremediation in mine soil. Samples were collected from a typical lead-zinc (Pb-Zn) mine to assess the microbial community structure of the HMs concentrated in the soil. The goal was to analyze the bacterial and fungal community structures and their interactions using the 16S rRNA genes and internal transcribed spacer high-throughput sequencing. Analyses at different sampling sites showed that contamination with HMs significantly reduced the bacterial richness and diversity but increased that of the fungi...
April 22, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38648003/integrated-evaluation-of-the-biological-response-of-the-earthworm-eisenia-fetida-using-two-glyphosate-exposure-strategies-soil-enriched-and-soils-collected-from-crops-in-southeastern-mexico
#24
JOURNAL ARTICLE
Ricardo Dzul-Caamal, Armando Vega-López, Jaime Rendón-von Osten
Under laboratory conditions, the toxicological effects of pesticides tend to be less variable and realistic than under field conditions, limiting their usefulness in environmental risk assessment. In the current study, the earthworm Eisenia fetida was selected as a bioindicator for assessing glyphosate toxic effects in two different trials to solve this dilemma. In Trial 1, the worms were exposed for 7 and 14 days to concentrations of a commercial glyphosate formulation (1 to 500 mg a.i. kg-1 ) currently used in the field...
April 22, 2024: Environmental Science and Pollution Research International
https://read.qxmd.com/read/38647902/influence-of-light-absorption-rate-on-the-astaxanthin-production-by-the-microalga-haematococcus-pluvialis-during-nitrogen-starvation
#25
JOURNAL ARTICLE
Khadija Samhat, Antoinette Kazbar, Hosni Takache, Ali Ismail, Jeremy Pruvost
Large amounts of astaxanthin (about 4% DW) can be produced under nitrogen starvation of Haematococcus pluvialis in photobioreactors (PBRs) exposed to high light conditions to induce a light stress. However, in PBR, the large biomass concentration usually achieved leads to strong light attenuation conditions, which makes complex the analysis of this "light stress". This study aims to elucidate the role of light transfer in astaxanthin cell content and productivity from the microalga Haematococcus pluvialis during nitrogen starvation...
November 9, 2023: Bioresources and Bioprocessing
https://read.qxmd.com/read/38647733/inroads-into-saline-alkaline-stress-response-in-plants-unravelling-morphological-physiological-biochemical-and-molecular-mechanisms
#26
REVIEW
Mansi Sharma, Rujira Tisarum, Ravinder Kumar Kohli, Daizy R Batish, Suriyan Cha-Um, Harminder Pal Singh
This article discusses the complex network of ion transporters, genes, microRNAs, and transcription factors that regulate crop tolerance to saline-alkaline stress. The framework aids scientists produce stress-tolerant crops for smart agriculture. Salinity and alkalinity are frequently coexisting abiotic limitations that have emerged as archetypal mediators of low yield in many semi-arid and arid regions throughout the world. Saline-alkaline stress, which occurs in an environment with high concentrations of salts and a high pH, negatively impacts plant metabolism to a greater extent than either stress alone...
April 22, 2024: Planta
https://read.qxmd.com/read/38647642/biochemistry-biomarkers-and-metal-levels-as-indicators-of-environmental-pollution-in-danio-rerio-exposed-to-the-sorocaba-river-s-p-brazil
#27
JOURNAL ARTICLE
Gabriel Hiroshi Fujiwara, Heidi Samantha Moraes Utsunomiya, João Victor Cassiel Ferraz, Davi Marques Gutierres, Isabela Ferreira Fernandes, Cleoni Dos Santos Carvalho
Metal contamination of the environment poses a significant threat to human health and can cause significant damage to aquatic ecosystems. Danio rerio was exposed to Sorocaba River water for 96 h from two different sites in summer (S) and winter (W). Concentrations of Al, Cd, Cu, Mn and Zn were determined in the exposure water and in sediment. At the end of the exposure, the concentrations of Al, Cu and Mn at the Ibiúna point (P1) and Mn at the Itupararanga point (P2) decreased compared to the initial concentrations in the water...
April 22, 2024: Ecotoxicology
https://read.qxmd.com/read/38647614/effect-of-adaptive-laboratory-evolution-of-engineered-escherichia-coli-in-acetate-on-the-biosynthesis-of-succinic-acid-from-glucose-in-two-stage-cultivation
#28
JOURNAL ARTICLE
Jiaping Jiang, Yuanchan Luo, Peng Fei, Zhengtong Zhu, Jing Peng, Juefeng Lu, Du Zhu, Hui Wu
Escherichia coli MLB (MG1655 ΔpflB ΔldhA), which can hardly grow on glucose with little succinate accumulation under anaerobic conditions. Two-stage fermentation is a fermentation in which the first stage is used for cell growth and the second stage is used for product production. The ability of glucose consumption and succinate production of MLB under anaerobic conditions can be improved significantly by using acetate as the solo carbon source under aerobic condition during the two-stage fermentation...
April 5, 2024: Bioresources and Bioprocessing
https://read.qxmd.com/read/38647388/cascade-reactions-catalyzed-by-gold-hybrid-nanoparticles-generate-co-gas-against-periodontitis-in-diabetes
#29
JOURNAL ARTICLE
Yi Wang, Tengda Chu, Ting Jin, Shengming Xu, Cheng Zheng, Jianmin Huang, Sisi Li, Lixia Wu, Jianliang Shen, Xiaojun Cai, Hui Deng
The treatment of diabetic periodontitis poses a significant challenge due to the presence of local inflammation characterized by excessive glucose concentration, bacterial infection, and high oxidative stress. Herein, mesoporous silica nanoparticles (MSN) are embellished with gold nanoparticles (Au NPs) and loaded with manganese carbonyl to prepare a carbon monoxide (CO) enhanced multienzyme cooperative hybrid nanoplatform (MSN-Au@CO). The Glucose-like oxidase activity of Au NPs catalyzes the oxidation of glucose to hydrogen peroxide (H2 O2 ) and gluconic acid,and then converts H2 O2 to hydroxyl radicals (•OH) by peroxidase-like activity to destroy bacteria...
April 22, 2024: Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
https://read.qxmd.com/read/38647306/surface-tension-of-aqueous-electrolyte-solutions-a-thermomechanical-approach
#30
JOURNAL ARTICLE
Yury A Budkov, Nikolai N Kalikin, Petr E Brandyshev
We determine the surface tension of aqueous electrolyte solutions in contact with non-polar dielectric media using a thermomechanical approach, which involves deriving the stress tensor from the thermodynamic potential of an inhomogeneous fluid. To obtain the surface tension, we calculate both the normal and tangential pressures using the components of the stress tensor, recently derived by us [Y. A. Budkov and P. E. Brandyshev, J. Chem. Phys. 159, 174103 (2023)] within the framework of Wang's variational field theory...
April 28, 2024: Journal of Chemical Physics
https://read.qxmd.com/read/38647201/experimental-evolution-of-extremotolerant-and-extremophilic-fungi-under-osmotic-stress
#31
JOURNAL ARTICLE
Farhad Hariri Akbari, Zewei Song, Martina Turk, Nina Gunde-Cimerman, Cene Gostinčar
Experimental evolution was carried out to investigate the adaptive responses of extremotolerant fungi to a stressful environment. For 12 cultivation cycles, the halotolerant black yeasts Aureobasidium pullulans and Aureobasidium subglaciale were grown at high NaCl or glycerol concentrations, and the halophilic basidiomycete Wallemia ichthyophaga was grown close to its lower NaCl growth limit. All evolved Aureobasidium spp. accelerated their growth at low water activity. Whole genomes of the evolved strains were sequenced...
April 22, 2024: IUBMB Life
https://read.qxmd.com/read/38647073/naringenin-mitigates-cadmium-induced-cell-death-oxidative-stress-mitochondrial-dysfunction-and-inflammation-in-kgn-cells-by-regulating-the-expression-of-sirtuin-1
#32
JOURNAL ARTICLE
Ben Yuan, Junbiao Mao, Junling Wang, Shuhong Luo, Bingbing Luo
The objective of this study was to examine the potential protective role of naringenin against the harmful effects induced by cadmium in KGN cell line. Cell viability was evaluated by cell counting kit-8 assay. Caspase-3/-9 activities were determined by caspase-3/-9 activity assay kits, respectively. Intracellular reactive oxygen species (ROS) level was detected by ROS-Glo™ H2 O2 Assay, antioxidant capacity was determined by a total antioxidant capacity assay kit. Mitochondrial membrane potential (MMP), ATP level, and ATP synthase activity were determined by JC-1, ATP assay kit, and ATP synthase activity assay kit, respectively...
April 22, 2024: Drug and Chemical Toxicology
https://read.qxmd.com/read/38647021/repurposing-of-antifungal-drug-flucytosine-flucytosine-cocrystals-for-anticancer-activity-against-prostate-cancer-targeting-apoptosis-and-inflammatory-signaling-pathways
#33
JOURNAL ARTICLE
Manimurugan Kanagavel, Rajan Marystella Sparjan Samuvel, Vaikundamoorthy Ramalingam, Sunil Kumar Nechipadappu
This study aimed to repurpose the antifungal drug flucytosine (FCN) for anticancer activity together with cocrystals of nutraceutical coformers sinapic acid (SNP) and syringic acid (SYA). The cocrystal screening experiments with SNP resulted in three cocrystal hydrate forms in which two are polymorphs, namely, FCN-SNP F-I and FCN-SNP F-II, and the third one with different stoichiometry in the asymmetric unit (1:2:1 ratio of FCN:SNP:H2 O, FCN-SNP F-III). Cocrystallization with SYA resulted in two hydrated cocrystal polymorphs, namely, FCN-SYA F-I and FCN-SYA F-II...
April 22, 2024: Molecular Pharmaceutics
https://read.qxmd.com/read/38646981/mangiferin-improves-early-porcine-embryonic-development-by-reducing-oxidative-stress
#34
JOURNAL ARTICLE
He-Wei Ji, Chao-Rui Wang, Xiu-Wen Yuan, Jing Wang, Lin Wang, Qi-Long Cao, Ying-Hua Li, Yong-Nan Xu, Nam-Hyung Kim
Mangiferin (MGN) is primarily found in the fruits, leaves, and bark of plants of the Anacardiaceae family, including mangoes. MGN exhibits various pharmacological effects, such as protection of the liver and gallbladder, anti-lipid peroxidation, and cancer prevention. This study aimed to investigate the effects of MGN supplementation during in vitro culture (IVC) on the antioxidant capacity of early porcine embryos and the underlying mechanisms involved. Porcine parthenotes in the IVC medium were exposed to different concentrations of MGN (0, 0...
April 2024: Reproduction in Domestic Animals
https://read.qxmd.com/read/38646760/effects-of-cu-2-o-nanoparticles-on-the-kinetic-characteristics-of-rapid-chlorophyll-fluorescence-induction-and-related-genes-in-wheat-seedlings
#35
JOURNAL ARTICLE
Wei Guo, Nan Wang, Kai-Yue Zhang, Pei-Pei Song, Zhan-Qiang Ma
Metal nanoparticles could be accumulated in soils, which threatens the ecological stability of crops. Investigating the effects of cuprous oxide nanoparticles (Cu2 O-NPs) on photosystem Ⅱ (PSⅡ) of wheat seedling leaves holds considerable importance in comprehending the implications of Cu2 O-NPs on crop photosynthesis. Following the hydroponic method, we investigated the effects of 0, 10, 50, 100, and 200 mg·L-1 Cu2 O-NPs on chlorophyll fluorescence induction kinetics and photosynthetic-related genes in wheat seedlings of "Zhoumai 18"...
March 18, 2024: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://read.qxmd.com/read/38646487/hand-grab-or-noose-pole-evaluating-the-least-stressful-practice-for-capture-of-endangered-turks-and-caicos-rock-iguanas-cyclura-carinata
#36
JOURNAL ARTICLE
Giuliano Colosimo, Gwyneth Montemuro, Gregory A Lewbart, Gabriele Gentile, Glenn Gerber
As the analysis of blood metabolites has become more readily accessible thanks to the use of point-of-care analyzers, it is now possible to evaluate stress level of wild animals directly in the field. Lactate is receiving much attention as a good stress level proxy in individuals subjected to capture, manual restraint, and data sampling in the wild, and appropriate protocols to maintain lactate values low should be preferred. In this study we compare how two different capture methodologies, hand grab vs. noose pole, affect the variation of blood lactate values in Cyclura carinata iguanas when captured for sampling...
2024: PeerJ
https://read.qxmd.com/read/38646477/effects-of-soil-ph-on-the-growth-soil-nutrient-composition-and-rhizosphere-microbiome-of-ageratina-adenophora
#37
JOURNAL ARTICLE
Yun Xia, Junna Feng, Hongbo Zhang, Deyu Xiong, Lingdong Kong, Robert Seviour, Yunhong Kong
Ageratina adenophora is an invasive weed species found in many countries. Methods to control the spread of this weed have been largely unsuccessful. Soil pH is the most important soil factor affecting the availability of nutrients for plant and impacting its growth. Understanding the mechanisms of the influence of soil pH on the growth of A. adenophora may help to develop effective control measures. In this study, we artificially changed the soil pH in pot experiments for A. adenophora . We studied the effects of acidic (pH 5...
2024: PeerJ
https://read.qxmd.com/read/38646467/comparative-finite-element-analysis-of-contact-and-stress-distribution-in-tibiotalar-articular-cartilage-healthy-versus-varus-ankles
#38
JOURNAL ARTICLE
Mohadese Rajaeirad, Morad Karimpour, Mohammad Reza Hairi Yazdi
BACKGROUND: The distribution of forces within the ankle joint plays a crucial role in joint health and longevity. Loading disorders affecting the ankle joint can have significant detrimental effects on daily life and activity levels. This study aimed to enhance our understanding of the mechanical behavior of tibiotalar joint articular cartilages in the presence of varus deformity using finite element analysis (FEA) applied to patient-specific models. METHODS: Two personalized ankle models, one healthy and another with varus deformity, were created based on CT scan images...
September 2024: Journal of Orthopaedics
https://read.qxmd.com/read/38646268/how-sharp-objects-injuries-impact-our-healthcare-workers-unveiling-perspective-and-preventive-imperatives
#39
JOURNAL ARTICLE
Ethar N Ibrahim, Soha Kannan, Laith Al Habahbeh, Omar H Makhamreh, Eman Khreisat, Martin Kakich, Issa Khoury, Mohammad Abu Kaff, Amro Odah, Anees Hjazeen, Saif A Jabali, Rami Alqroom
Introduction Sharp object injuries in the medical field present a considerable occupational hazard for healthcare workers (HCWs), encompassing a spectrum of consequences from immediate discomfort to enduring health consequences. These injuries may expose HCWs to potential infections. Despite efforts to control sharp object injuries in healthcare environments, they are present at every stage involving using or disposing of medical sharp instruments. In Jordan, limited research has focused on sharp object injuries, with most data included from studies concentrating on practicing nurses or nursing students...
March 2024: Curēus
https://read.qxmd.com/read/38646205/post-traumatic-stress-disorder-the-influence-of-the-environmental-context-and-analysis-of-oxidative-stress-and-inflammatory-and-glycemic-markers-in-women-living-in-kurdistan-regional-government-iraq
#40
JOURNAL ARTICLE
Husni M Hasan, Suad Y Alkass, Daniele S Persike
Background Internally displaced persons (IDP) camps are still home to a large number of female survivors of the Yazidi genocide carried out in Iraq in 2014 by the Islamic organization known as the Islamic State of Iraq and Syria (ISIS). Many of these women suffer from a persistent form of post-traumatic stress disorder (PTSD), which can last for many years. On the other hand, little is known about the intricate etiology of PTSD. Objectives In this observational cross-sectional study, the biochemical parameters, including inflammatory and oxidative stress (OXS) markers, were evaluated in two groups: the case group (women with newly diagnosed PTSD) and the control group (apparently healthy women)...
March 2024: Curēus
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