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Structural health monitoring

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https://www.readbyqxmd.com/read/30516131/recombinant-%C3%AE-and-%C3%AE-tubulin-from-echinococcus-granulosus-expression-purification-and-polymerization
#1
Congshan Liu, Jiaqing Yao, Jianhai Yin, Jian Xue, Haobing Zhang
Echinococcosis, which causes a high disease burden and is of great public health significance, is caused by the larval stage of Echinococcus species. It has been suggested that tubulin is the target of benzimidazoles, the only drugs for the treatment of echinococcosis. This study evaluated the characteristics of tubulins from Echinococcus granulosus. The full-length cDNAs of E. granulosus α- and β-tubulin isoforms were cloned by reverse transcription PCR from protoscolex RNA. Then, these two tubulin isoforms (α9 and β4 ) were recombinantly expressed as insoluble inclusion bodies in Escherichia coli...
2018: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/30515012/scalable-architecture-for-telemonitoring-chronic-diseases-in-order-to-support-the-cdsss-in-a-common-platform
#2
Azita Yazdani, Reza Safdari, Marjan Ghazisaeedi, Hamid Beigy, Roxana Sharifian
Introduction: In recent years, a variety of clinical decision-support systems (CDSS) have been developed to monitor the health of patients with chronic disease from far away. These systems are effective in overcoming human resource limitation and analyzing information generated by Tele-monitoring systems. These systems, however, are limited to monitoring a particular disease, which allows them to be used only in one specific disease. In reuses of these systems to monitor other diseases, we need to re-establish a new system with a new knowledge base...
October 2018: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/30514317/using-concept-mapping-to-identify-policy-options-and-interventions-towards-people-centred-health-care-services-a-multi-stakeholders-perspective
#3
Christine Cécile Leyns, Jan De Maeseneer, Sara Willems
BACKGROUND: People-centred health care (PCC) services are identified by the WHO as important building blocks towards universal health coverage. In 2016 the WHO formulated a comprehensive framework on integrated PCC services based on an international expert consultation. Yet, expert opinions may fail to recognize the needs of all health system stakeholders. Therefore, a consultation method that includes the health workforce and laypersons, can be instrumental to elaborate this framework more in-depth...
December 4, 2018: International Journal for Equity in Health
https://www.readbyqxmd.com/read/30513697/responding-to-climate-and-environmental-change-impacts-on-human-health-via-integrated-surveillance-in-the-circumpolar-north-a-systematic-realist-review
#4
REVIEW
Alexandra Sawatzky, Ashlee Cunsolo, Andria Jones-Bitton, Jacqueline Middleton, Sherilee L Harper
Environments are shifting rapidly in the Circumpolar Arctic and Subarctic regions as a result of climate change and other external stressors, and this has a substantial impact on the health of northern populations. Thus, there is a need for integrated surveillance systems designed to monitor the impacts of climate change on human health outcomes as part of broader adaptation strategies in these regions. This review aimed to identify, describe, and synthesize literature on integrated surveillance systems in Circumpolar Arctic and Subarctic regions, that are used for research or practice...
November 30, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/30511719/fluorescence-based-detection-of-polychlorinated-biphenyls-pcbs-in-water-using-hydrophobic-interactions
#5
Irfan Ahmad, Jiaying Weng, A J Stromberg, J Z Hilt, T D Dziubla
Despite increasing controls in their production and disposal, persistent organic pollutants in water, even at concentrations below parts per million, represent an ongoing environmental health risk. Despite this concern, the detection of these compounds in water sources rely upon expensive, time consuming approaches that do not permit frequent monitoring and evaluation. In this work, a new fluorescence-based technique is presented for the detection of polychlorinated biphenyls (PCBs) in water. Benzopyrene (BaP) fluorescence was shown to increase with trace concentrations of aromatic organic pollutants...
December 4, 2018: Analyst
https://www.readbyqxmd.com/read/30509522/health-monitoring-through-wearable-technologies-for-older-adults-smart-wearables-acceptance-model
#6
Junde Li, Qi Ma, Alan Hs Chan, S S Man
In the context of a fast aging population, ubiquitous usage of smart wearable systems can alleviate the social burden caused by the increasing need of older adults for healthcare and assistance. To facilitate and encourage the use of smart wearable systems among older adults, this study investigated the factors that contribute to the acceptance of such systems, and smart wearables acceptance model for older adults was developed using structural equation modeling. The model was validated using 146 survey samples collected from adults aged 60 years and above...
February 2019: Applied Ergonomics
https://www.readbyqxmd.com/read/30509172/genome-wide-comparison-of-corynebacterium-diphtheriae-isolates-from-australia-identifies-differences-in-the-pan-genomes-between-respiratory-and-cutaneous-strains
#7
Verlaine J Timms, Trang Nguyen, Taryn Crighton, Marion Yuen, Vitali Sintchenko
BACKGROUND: Corynebacterium diphtheriae is the main etiological agent of diphtheria, a global disease causing life-threatening infections, particularly in infants and children. Vaccination with diphtheria toxoid protects against infection with potent toxin producing strains. However a growing number of apparently non-toxigenic but potentially invasive C. diphtheriae strains are identified in countries with low prevalence of diphtheria, raising key questions about genomic structures and population dynamics of the species...
December 4, 2018: BMC Genomics
https://www.readbyqxmd.com/read/30508424/ensuring-fairness-in-machine-learning-to-advance-health-equity
#8
Alvin Rajkomar, Michaela Hardt, Michael D Howell, Greg Corrado, Marshall H Chin
Machine learning is used increasingly in clinical care to improve diagnosis, treatment selection, and health system efficiency. Because machine-learning models learn from historically collected data, populations that have experienced human and structural biases in the past-called protected groups-are vulnerable to harm by incorrect predictions or withholding of resources. This article describes how model design, biases in data, and the interactions of model predictions with clinicians and patients may exacerbate health care disparities...
December 4, 2018: Annals of Internal Medicine
https://www.readbyqxmd.com/read/30508032/2018-update-on-medical-overuse
#9
Daniel J Morgan, Sanket S Dhruva, Eric R Coon, Scott M Wright, Deborah Korenstein
Importance: Overuse of medical care is a well-recognized problem in health care, associated with patient harm and costs. We sought to identify and highlight original research articles published in 2017 that are most relevant to understanding medical overuse. Observations: A structured review of English-language articles published in 2017 was performed, coupled with examination of tables of contents of high-impact journals to identify articles related to medical overuse in adult care...
December 3, 2018: JAMA Internal Medicine
https://www.readbyqxmd.com/read/30507286/senior-stakeholder-views-on-policies-to-foster-a-culture-of-openness-in-the-english-national-health-service-a-qualitative-interview-study
#10
Graham Paul Martin, Sarah Chew, Mary Dixon-Woods
OBJECTIVES: To examine the experiences of clinical and managerial leaders in the English healthcare system charged with implementing policy goals of openness, particularly in relation to improving employee voice. DESIGN: Semi-structured qualitative interviews. SETTING: National Health Service, regulatory and third-sector organisations in England. PARTICIPANTS: Fifty-one interviewees, including senior leaders in healthcare organisations (38) and policymakers and representatives of other relevant regulatory, legal and third-sector organisations (13)...
December 3, 2018: Journal of the Royal Society of Medicine
https://www.readbyqxmd.com/read/30505897/sdnet2018-an-annotated-image-dataset-for-non-contact-concrete-crack-detection-using-deep-convolutional-neural-networks
#11
Sattar Dorafshan, Robert J Thomas, Marc Maguire
SDNET2018 is an annotated image dataset for training, validation, and benchmarking of artificial intelligence based crack detection algorithms for concrete. SDNET2018 contains over 56,000 images of cracked and non-cracked concrete bridge decks, walls, and pavements. The dataset includes cracks as narrow as 0.06 mm and as wide as 25 mm. The dataset also includes images with a variety of obstructions, including shadows, surface roughness, scaling, edges, holes, and background debris. SDNET2018 will be useful for the continued development of concrete crack detection algorithms based on deep convolutional neural networks (DCNNs), which are a subject of continued research in the field of structural health monitoring...
December 2018: Data in Brief
https://www.readbyqxmd.com/read/30501942/an-experience-in-integrated-management-of-clinical-risks
#12
A I Fernández-Castelló, P Valle-Pérez, M L Pagonessa-Damonte, M Blazquez-Muñoz, J F Tomás
BACKGROUND: Manage clinical risks under the integrated risk management model of the BUPA organization (British United Provident Association). MATERIALS AND METHODS: BUPA is an international group that provides health insurance and healthcare services. The project has been limited to Europe and Latin America (ELA) and this article presents the results related to hospitals. The integral risk management model was based on a governance structure, a risk management framework and the risk management itself (continuous process of identification, evaluation, management, monitoring and reporting)...
November 27, 2018: Journal of healthcare quality research
https://www.readbyqxmd.com/read/30501471/finding-fit-school-nurses-lead-the-way-in-the-development-of-employee-wellness-program
#13
Jasmine Wood, Althea Huggins, Lisa Clausen, Stefani Lailari
School nurses are in a unique position to monitor and influence not only the health of students but also the health of school employees. The National Association of School Nurses (NASN) provides support and evidence-based best practice guidelines for the specialty practice of school nursing. NASN's Framework for 21st Century School Nursing Practice™ provides a road map for a healthy and safe school environment. With a focus on student health and academic success, the framework also aligns with the whole school, whole community, whole child model to provide a collaborative structure to learning and health...
December 3, 2018: NASN School Nurse
https://www.readbyqxmd.com/read/30501187/facile-preparation-of-a-bacteria-imprinted-artificial-receptor-for-highly-selective-bacterial-recognition-and-label-free-impedimetric-detection
#14
Jikui Wu, Ruinan Wang, Yunfei Lu, Min Jia, Juan Yan, Xiaojun Bian
The effective identification and quantification of pathogenic bacteria is essential for addressing serious public health issues. Here we demonstrate a simple and universal impedimetric sensor for highly selective and sensitive detection of pathogenic bacteria based on the recognition by a bacteria-imprinted polypyrrole (BIP) film. The BIP film was facilely prepared via one-step electro-polymerization followed by in-situ removal of the bacterial template. The film structure is novel with non-cavity-like imprinted sites situated at the surface of the polypyrrole (PPy) matrix, which are more accessible for the target bacteria and should enhance the mass transfer and the binding kinetics...
December 3, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/30501168/mechanically-guided-assembly-of-monolithic-3d-structures-from-elastomer-composites
#15
Jheng-Wun Su, Jianhua Wang, Yonggang Zheng, Shan Jiang, Jian Lin
Mechanically guided assembly is considered as a facile and scalable methodology for fabrication of three-dimensional (3D) structures. However, most of the previous methods require multistep processes for bonding bi- or multi-layers and only result in non-freestanding 3D structures due to usage of a supporting elastomer substrate. Herein, we report a functional elastomer composite that can be transformed to a freestanding and monolithic 3D structure driven by the mechanically guided assembly. Photolithography can be used to selectively tune the mechanical properties of UV exposed regions which exhibit enhanced elasticity compared with the non-exposed regions...
December 3, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/30500731/three-dimensional-cameras-and-skeleton-pose-tracking-for-physical-function-assessment-a-review-of-uses-validity-current-developments-and-kinect-alternatives
#16
REVIEW
Ross A Clark, Benjamin F Mentiplay, Emma Hough, Yong Hao Pua
BACKGROUND: Three-dimensional camera systems that integrate depth assessment with traditional two-dimensional images, such as the Microsoft Kinect, Intel Realsense, StereoLabs Zed and Orbecc, hold great promise as physical function assessment tools. When combined with point cloud and skeleton pose tracking software they can be used to assess many different aspects of physical function and anatomy. These assessments have received great interest over the past decade, and will likely receive further study as the integration of depth sensing and augmented reality smartphone cameras occurs more in everyday life...
November 22, 2018: Gait & Posture
https://www.readbyqxmd.com/read/30500351/anodal-tdcs-improves-attentional-control-in-older-adults
#17
Claire J Hanley, Andrea Tales
Transcranial direct current stimulation (tDCS) facilitates cognitive enhancement by directly increasing neuroplasticity, and has shown promising results as an external intervention to attenuate age-related cognitive decline. However, stimulation protocols have failed to account for age-associated changes in brain structure and the present literature omits investigation of attentional control, despite the occurrence of substantial inhibitory processing deficits with age. To provide new insight into the benefits of tDCS, the objective of this study was to develop an age-optimised stimulation protocol in which key parameters (amplitude, duration, and electrode configuration) were selected in accordance with knowledge of stimulation effects, specific to the ageing brain...
November 27, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/30500093/paediatric-and-adult-bronchiectasis-monitoring-cross-infection-role-of-multidisciplinary-teams-and-self-management-plans
#18
REVIEW
Vidya Navaratnam, Douglas L Forrester, Kah Peng Eg, Anne B Chang
Bronchiectasis is a chronic lung disease associated with structurally abnormal bronchi, clinically manifested by a persistent wet/productive cough, airway infections and recurrent exacerbations. Early identification and treatment of acute exacerbations is an integral part of monitoring and annual review, in both adults and children, to minimize further damage due to infection and inflammation. Common modalities used to monitor disease progression include clinical signs and symptoms, frequency of exacerbations and/or number of hospital admissions, lung function (forced expiratory volume in 1 s (FEV1 )% predicted), imaging (radiological severity of disease) and sputum microbiology (chronic infection with Pseudomonas aeruginosa)...
November 30, 2018: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/30499901/clinical-workflows-and-the-associated-tasks-and-behaviors-to-support-delivery-of-integrated-behavioral-health-and-primary-care
#19
Melinda M Davis, Rose Gunn, Maribel Cifuentes, Parinda Khatri, Jennifer Hall, Emma Gilchrist, C J Peek, Mindy Klowden, Jeremy A Lazarus, Benjamin F Miller, Deborah J Cohen
Integrating primary care and behavioral health is an important focus of health system transformation. Cross-case comparative analysis of 19 practices in the United States describing integrated care clinical workflows. Surveys, observation visits, and key informant interviews analyzed using immersion-crystallization. Staff performed tasks and behaviors-guided by protocols or scripts-to support 4 workflow phases: (1) identifying; (2) engaging/transitioning; (3) providing treatment; and (4) monitoring/adjusting care...
January 2019: Journal of Ambulatory Care Management
https://www.readbyqxmd.com/read/30497515/improving-immunization-capacity-in-ethiopia-through-continuous-quality-improvement-interventions-a-prospective-quasi-experimental-study
#20
Tsegahun Manyazewal, Alemayehu Mekonnen, Tesfa Demelew, Semegnew Mengestu, Yusuf Abdu, Dereje Mammo, Workeabeba Abebe, Belay Haffa, Daniel Zenebe, Bogale Worku, Amir Aman, Setegn Tigabu
BACKGROUND: Strong scientific evidence is needed to support low-income countries in building effective and sustainable immunization programs and proactively engaging in global vaccine development and implementation initiatives. This study aimed to implement and evaluate the effectiveness of system-wide continuous quality improvement (CQI) interventions to improve national immunization programme performance in Ethiopia. METHODS: The study used a prospective, quasi-experimental design with an interrupted time-series analysis to collect data from 781 government health sectors (556 healthcare facilities, 196 district health offices, and 29 zonal health departments) selected from developing and emerging regions in Ethiopia...
November 30, 2018: Infectious Diseases of Poverty
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