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Endometriosis surgery

Soo Youn Song, Mia Park, Geon Woo Lee, Ki Hwan Lee, Ha Kyun Chang, Sang Mi Kwak, Heon Jong Yoo
OBJECTIVE: To compare the efficacy of levonorgestrel releasing intrauterine system (LNG-IUS) with other treatments as a postoperative maintenance therapy for endometriosis in terms of pain reduction, recurrence prevention, side effects and patients' satisfaction. STUDY DESIGN: We searched MEDLINE, EMBASE, and the Cochrane Library from January 1986 until February 2018. Two evaluators independently extracted and reviewed prospective and retrospective articles based on pre-determined selection criteria...
October 9, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Mariko Miyashita, Kaori Koga, Arisa Takeuchi, Tomoko Makabe, Ayumi Taguchi, Yoko Urata, Gentaro Izumi, Masashi Takamura, Miyuki Harada, Tetsuya Hirata, Yasushi Hirota, Osamu Wada-Hiraike, Osamu Yoshino, Tomoyuki Fujii, Yutaka Osuga
OBJECTIVE: The aim of this study was to clarify the expression of Ninj1 in endometriosis and adenomyosis lesions, and its inductive factor in human endometriotic stromal cells (ESCs). BACKGROUND: Nerve injury-induced protein 1 (Ninj1) is a molecule originally identified in dorsal root ganglion neurons and Schwann cells after nerve injury and promotes neurite outgrowth. The aim of this study was to clarify the expression of Ninj1 in endometriosis and adenomyosis lesions, and its inductive factor in human endometriotic stromal cells (ESCs)...
October 16, 2018: Reproductive Sciences
Sunwoo Park, Whasun Lim, Gwonhwa Song
Endometriosis is a benign gynecological disease of women of reproductive ages, wherein endometrial cells grow ectopically, decreasing their quality of life due to chronic pelvic pain and severe dysmenorrhea. Although surgery and hormone therapies are gold standards for treating endometriosis, side effects are common and the recurrence rate is nearly 50%. Recent studies are exploring phytochemicals as pharmacological adjuvants for treating endometriosis. Delphinidin is an anthocyanin with anti-inflammatory, antioxidative, and anticancerous properties...
October 15, 2018: Journal of Cellular Biochemistry
Jennifer C Pontré, Jessica M A Yin, Bernadette Brown, Krishnan Karthigasu, Bernadette McElhinney
Introduction: Whilst endometriosis is a relatively common condition, deeply infiltrating endometriosis (DIE) of the bladder is less so, and when medical treatment fails, surgical management is an effective option. We present a case report and surgical video of a patient undergoing combined laparoscopic and cystoscopic excision of deeply infiltrating endometriosis of the bladder. Design: Case report (Canadian Task Force Classification III) and step-by-step explanation of the surgery using video...
November 2018: Annals of Medicine and Surgery
Berrin Göktuğ Kadioglu, Yakup Kumtepe, Firdevs Sekerci Baran
OBJECTIVES: In recent years, the rapid development of minimally invasive surgical methods, including robotic surgery, has resulted in a marked decline of the traditional methods in gynaecological surgery. The aim of the study was to share our experience with robotic surgery at a state hospital. MATERIAL AND METHODS: A total of 40 patients, who underwent robotic gynaecological surgery (GS) between 2015 and 2017, were included. Age, BMI, previous abdominal operations (PAO), operation indications (OI), operative time (OT), pathological evaluation, uterine weight (UW), blood loss during surgery (BL), complications, and duration of the hospitalization (DoH) were analyzed...
2018: Ginekologia Polska
Artur Ludwin, Inga Ludwin, Bala Bhagavath, Wellington P Martins, Steven R Lindheim
OBJECTIVES: To demonstrate the hymen-sparing management of a blind hemivagina in obstructed hemivagina and ipsilateral renal anomaly (OHVIRA) syndrome with the use of transrectal ultrasound (TRUS)-guided vaginoscopic septoplasty supported by pre- and postoperative diagnostics with the use of a novel ultrasound technique: 3-dimensional saline-solution infusion contrast sonovaginocervicography (3D-SVC) with virtual speculoscopy. DESIGN: Video presentation of surgical and ultrasound techniques...
October 2018: Fertility and Sterility
Lei Zhan, Shun Yao, Shiying Sun, Qian Su, Jun Li, Bing Wei
OBJECTIVE: To investigate the levels of NLRC5 and autophagy in women with leiomyoma and endometriosis and the correlation between NLRC5 level and autophagy level. DESIGN: Case-control study. SETTING: Clinics. PATIENT(S): Sixty-five patients were recruited: 30 women with endometriosis were compared with 35 women with leiomyoma. INTERVENTION(S): Endometriosis was definitively diagnosed during surgery by laparoscopy or laparotomy and was confirmed by histopathological evaluation (n=30)...
October 2018: Fertility and Sterility
Roxana Kargar, Vasilis Minas, Atefeh Gorgin Karaji, Khadijeh Shadjoo, Roya Padmehr, Arash Mohazzab, Anahita Enzevaei, Saghar Samimi Sadeh, Koorosh Kamali, Shaheen Khazali
OBJECTIVE: To compare the efficiency of laparoscopically-guided transversus abdominis plane block (LTAP) versus port-site local anaesthetic infiltration (LAI) in reducing postoperative pain following laparoscopic excision of endometriosis. DESIGN: A prospective, double-blind randomized controlled trial. SETTING: A tertiary referral centre for endometriosis and minimally invasive gynaecological surgery. POPULATION: Women undergoing laparoscopic excision of endometriosis from December 2015 through July 2016...
October 13, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
Daniela Alberico, Edgardo Somigliana, Benedetta Bracco, Dridi Dhouha, Anna Roberto, Paola Mosconi, Federica Facchin, Paolo Vercellini
OBJECTIVE: To explore the potential benefits of pregnancy on endometriosis symptoms. This is a retrospective study that has been conducted at Academic department and referral center for endometriosis. STUDY DESIGN: We included all conservative women who had a live birth after at least one surgery for endometriosis and who reported pre-pregnancy moderate to severe pelvic pain symptoms (at least one among dysmenorrhea, deep dyspareunia, non menstrual pelvic pain and dyschezia)...
August 22, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Rachael Hemmert, Karen C Schliep, Sydney Willis, Charles Matthew Peterson, Germaine Buck Louis, Kristina Allen-Brady, Sara E Simonsen, Joseph B Stanford, Jiyoung Byun, Ken R Smith
BACKGROUND: Caffeine, alcohol, smoking and physical activity are known to alter sex steroid synthesis, which may affect hormone-dependent gynaecologic disease risk, such as endometriosis; however, few studies have assessed life style factors prior to endometriosis diagnosis. METHODS: Four hundred and seventy three women, ages 18-44 years, underwent laparoscopy or laparotomy, regardless of clinical indication, at 14 clinic sites, 2007-2009. Women with prior surgically confirmed endometriosis were excluded...
October 11, 2018: Paediatric and Perinatal Epidemiology
M Candiani, J Ottolina, E Posadzka, S Ferrari, L M Castellano, I Tandoi, L Pagliardini, A Nocun, R Jach
STUDY QUESTION: Does CO2 laser vaporization offer better results in treating endometrioma in terms of ovarian reserve preservation compared to traditional cystectomy? SUMMARY ANSWER: Assessing both antral follicle count (AFC) and serum anti-Müllerian hormone (AMH) levels as measures of ovarian reserve, the results suggest that CO2 technology may be an alternative treatment for endometrioma, causing minimal damage to adjacent healthy ovarian tissue. WHAT IS KNOWN ALREADY: Excisional surgery has been questioned as an ideal surgical approach for endometriomas because it is associated with potential reduction of ovarian reserve...
October 9, 2018: Human Reproduction
María L Sánchez-Ferrer, Raquel Jiménez-Velázquez, Jaime Mendiola, María T Prieto-Sánchez, Laura Cánovas-López, Ana Carmona-Barnosi, Shiana Corbalán-Biyang, Ana I Hernández-Peñalver, Evdochia Adoamnei, Aníbal Nieto, Alberto M Torres-Cantero
OBJECTIVE: To assess the predictive ability of a combination of anogenital distance (AGD) and anti-Müllerian hormone (AMH) to diagnosis the presence of endometriosis without surgery. METHODS: The present study included women diagnosed with endometriosis and a control group who attended the "Virgen de la Arrixaca" University Hospital, Murcia, Spain, between September 1, 2014, and May 31, 2015. Serum concentrations of AMH were measured, and two AGD measurements were obtained: from the anterior clitoral surface to the upper verge of the anus (AGDAC ), and from the posterior fourchette to the upper verge of the anus (AGDAF )...
October 9, 2018: International Journal of Gynaecology and Obstetrics
Lucie Allègre, Patrick Aristizabal, Krystel Nyangoh Timoh, Isabelle Thomassin-Naggara, Edith Kermarrec, Sofiane Bendifallah, Emile Darai
STUDY OBJECTIVE: To compare 1.5-Tesla (1.5 T) to 3-Tesla (3 T) Magnetic resonance enterography (MRE) in assessing multifocal (multiple lesions affecting the same segment) and multicentric (multiple lesions affecting several digestive segments) bowel endometriosis in patients with suspected-colorectal endometriosis, in routine practice. STUDY DESIGN: We conducted a retrospective, comparative study in Tenon University Hospital, Paris, France. We included patients scheduled for colorectal resection from April 2014 to February 2018...
September 25, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Bairavi Manoharan, Asma S Haider, Asgari Mowahed Samira, Balamurali Bharathan, Adolfo Parra-Blanco
An inverted (intussuscepted) appendix is a rare finding, often mistaken for a polyp as it presents with vague symptoms. This can result in misdiagnosis and inappropriate management. Diagnosis is usually made through surgery. Rarely, endometriosis has been found as the cause of the intussusception. A 42-year-old woman presented with frequent loose stools over 2 years, an elevated calprotectin over 400 μg/g faeces (normal <110) and a serum C-reactive protein of 40 mg/l (normal <5 mg/l). Endoscopy showed an inverted appendix...
October 2018: Oxford Medical Case Reports
Uri P Dior, Debbie Nisbet, Jenny N Fung, Grant Foster, Martin Healey, Grant W Montgomery, Peter Aw Rogers, Sarah J Holdsworth-Carson, Jane E Girling
STUDY OBJECTIVE: To examine the presence of sonographic evidence of adenomyosis (SEOA) in patients undergoing laparoscopic surgery for investigation of endometriosis and to assess if there is an association between SEOA and endometriosis severity. Using gene expression analysis, we also aimed to determine if gene expression in eutopic endometrium differed in patients with and without adenomyosis. DESIGN: A prospective study (Canadian Task Force classification II-2)...
September 28, 2018: Journal of Minimally Invasive Gynecology
Cécile Bermot, Pénélope Labauge, Olivier Limot, Anne Louboutin, Arnaud Fauconnier, Cyrille Huchon
OBJECTIVE: To study the performance of MRI for the detection of anterior pelvic endometriotic lesions. MATERIALS AND METHODS: We carried out a retrospective, single site, case-controlled study of patients who underwent surgery for endometriosis between March 2005 and December 2013. Laparoscopy was used to obtain the reference diagnosis of the endometriotic lesions. We age-matched patients with anterior endometriosis with those with isolated posterior endometriosis for reference...
September 28, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Hae-Won Kim, Jeong-Eun Yoo
Endometriosis is a common benign gynecologic tumor, and it can destroy a patient's life. Surgery and hormone therapy are established therapies for endometriosis. However, there are many cases of recurrent endometriosis after conventional therapies. This report presents a case of a patient who has repetitive recurrence of endometriosis after laparoscopic excision and hormone therapy. A 32-years-old female patient first had laparoscopic surgery to remove endometriosis in 2011. The disease recurred two more times after the first excision...
September 2018: Integrative Medicine Research
Kristina Arion, Tuba Aksoy, Catherine Allaire, Heather Noga, Christina Williams, Mohamed A Bedaiwy, Paul J Yong
STUDY OBJECTIVE: To evaluate point-of-care pre-operative transvaginal ultrasound (TVUS) sliding sign, in comparison to palpation of a nodule on digital pelvic examination, for the prediction of pouch of Douglas (POD) obliteration. DESIGN: Analysis of data from a prospective data registry (Canadian Task Force Classification II-2). SETTING: Tertiary referral center. PATIENTS: Women with suspected endometriosis who had pre-operative pelvic examination and point-of-care TVUS, followed by laparoscopic surgery between August 2015 and December 2016...
September 26, 2018: Journal of Minimally Invasive Gynecology
Üzeyir Kalkan, Angelos Daniilidis
Deep infiltrating endometriosis (DIE) is a particular form of endometriosis causing a variety of severe pelvic pain in women. Involvement of peripheral nerves by DIE implants is very rare. The most common involved site is the sacral plexus. There are few reported cases of involvement of obturator nerve by DIE. To our knowledge, only 6 cases of symptomatic obturator nerve involvement by DIE have been described (according to PubMed database search in July 2018) and 3 of them were treated laparoscopically. We report a rare case of deep infiltrating endometriotic nodule entrapping the right obturator nerve...
September 25, 2018: Journal of Minimally Invasive Gynecology
Mahnaz Ashrafi, Arezoo Arabipoor, Mandana Hemat, Reza Salman-Yazdi
This case-control study was designed to evaluate the impact of endometriosis and the presence of endometrioma (OMA) per se on the serum anti-Müllerian hormone (AMH) level and also to compare the in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI) outcomes after therapeutic surgery in endometriosis patients, according to the localisation of endometriosis lesions. One hundred and fifty two infertile women ≤40 years with suspicious symptoms were surgically evaluated to detect the aetiology of infertility at the Royan Institute during this study and, in parallel, 131 patients with a male factor infertility diagnosis were considered as the control group...
September 26, 2018: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
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