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https://www.readbyqxmd.com/read/28937267/surface-transperineal-ultrasound-and-vaginal-abnormalities-applications-and-strengths
#1
Soha Talaat Hamed, Sahar Mahmoud Mansour
The role of ultrasound in the assessment of the female pelvis whether using transabdominal/ transluminal approach is well established. Little reported about the use of the superficial transperineal approach that could provides full assessment of the lower cervix and vagina which may be overlooked in the standard examinations. Proximity of the probe to the vagina helps not just the detection of organ abnormalities yet also proper characterization and differentiation of vaginal masses. Advances in Knowledge: The indications, technique of scanning and limitations of transperineal ultrasound in the evaluation of the lower uterine segment...
September 13, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28931859/a-longitudinal-analysis-of-the-vaginal-microbiota-and-vaginal-immune-mediators-in-women-from-sub-saharan-africa
#2
Vicky Jespers, Jordan Kyongo, Sarah Joseph, Liselotte Hardy, Piet Cools, Tania Crucitti, Mary Mwaura, Gilles Ndayisaba, Sinead Delany-Moretlwe, Jozefien Buyze, Guido Vanham, Janneke H H M van de Wijgert
In cross-sectional studies increased vaginal bacterial diversity has been associated with vaginal inflammation which can be detrimental for health. We describe longitudinal changes at 5 visits over 8 weeks in vaginal microbiota and immune mediators in African women. Women (N = 40) with a normal Nugent score at all visits had a stable lactobacilli dominated microbiota with prevailing Lactobacillus iners. Presence of prostate-specific antigen (proxy for recent sex) and being amenorrhoeic (due to progestin-injectable use), but not recent vaginal cleansing, were significantly associated with microbiota diversity and inflammation (controlled for menstrual cycle and other confounders)...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28930604/therapeutic-startegies-for-human-papillomavirus-infection-and-associated-cancers
#3
Alok Chandra Bharti, Tejveer Singh, Anjali Bhat, Deepti Pande, Mohit Jadli
Human papillomavirus (HPV) infection is linked to development of cancer of cervix, vagina, vulva, penis, ano-genital and non-genital oro-pharyngeal sites. HPV being a sexually transmitted virus infects both genders equally but with higher chances of pathological outcome in women. In the absence of organized screening programs, women report HPV-infected lesions at relatively advanced stages where they are subjected to standard treatments that are not HPV-specific. HPV infection-driven lesions usually take 10-20 years for malignant progression and are preceded by well-characterized pre-cancer stages...
January 1, 2018: Frontiers in Bioscience (Elite Edition)
https://www.readbyqxmd.com/read/28928886/vulvar-cancer-in-china-epidemiological-features-and-risk-analysis
#4
Xue Xiao, Yi-Bo Meng, Peng Bai, Juan Zou, Ya Zhang, Tri M Bui Nguyen, Jian-Guo Xiao, Xue-Mei Gao, Bang-Fen Wen
Objective: Describe for the first time the clinical, epidemiological features of vulvar cancer in southwest China. Identify risk factors and provide reference for the prevention of vulvar cancer. Method: We retrospectively analyzed 885 patients admitted to the West China Second University Hospital for vulvar diseases between 2006 and 2016. Vulvar cancer patients with previously diagnosed vulvar nonneoplastic epithelial disorders (n=132) were analyzed and compared to those without prior history of vulvar nonneoplastic epithelial disorders (n=219)...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28928035/molecular-analysis-of-three-clostridium-difficile-strain-genomes-isolated-from-pig-farm-related-samples
#5
I Martín-Burriel, S Andrés-Lasheras, F Harders, R C Mainar-Jaime, B Ranera, P Zaragoza, V Falceto, Y Bolea, E Kuijper, R Bolea, A Bossers, M Chirino-Trejo
Clostridium difficile is an anaerobic spore-forming bacillus that usually causes gastrointestinal disorders in man and other animal species. Most of the strains isolated from animals are toxigenic being the virulent ribotype (RT) 078 predominant in several animal species. Although C. difficile is pathogenic to both humans and animals, there is no direct evidence of zoonosis. Deep genome sequencing provides sufficient resolution to analyse which strains found in animals might be related to human pathogens. So far, there are only a few fully sequenced genomes of C...
September 16, 2017: Anaerobe
https://www.readbyqxmd.com/read/28921932/fetal-mri-compared-to-ultrasound-for-the-diagnosis-of-obstructive-genital-malformations
#6
Anne Elodie Millischer, David Grevent, Véronique Rousseau, Neil O'Gorman, Pascale Sonigo, Bettina Bessieres, Yves Ville, Nathalie Boddaert, Laurent J Salomon
OBJECTIVE: To compare the accuracy of Magnetic Resonance Imaging (MRI) and ultrasound (US) to diagnose and characterize congenital obstructive genital abnormalities. METHOD: Retrospective cohort of 20 fetuses who underwent a fetal MRI following an ultrasound diagnosis of obstructive urogenital malformation. We compared MRI and US findings and their correlation with the definitive diagnosis. RESULT: The correct diagnosis was obtained in 6/20 (30%) cases and 19/20 cases (95%) with US and MRI respectively...
September 16, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28919146/m%C3%A3-llerian-agenesis-in-cat-eye-syndrome-and-22q11-chromosome-abnormalities-a-case-report-and-literature-review
#7
Abdulmajeed AlSubaihin, John VanderMeulen, Kate Harris, John Duck, Elizabeth McCready
BACKGROUND: Although Müllerian agenesis is the second most common cause of primary amenorrhea the underlying etiology in the majority of cases is unknown. Müllerian agenesis has been reported as a rare finding associated with chromosomal aberrations of the 22q11 chromosomal region including at least one individual with cat eye syndrome (CES) and 10 individuals with deletions or duplications of the 22q11.2 region. However, a potential link between 22q11 abnormalities and uterine malformations has been difficult to adequately ascertain given the limited case reports in the literature...
September 14, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28918284/new-insights-into-human-female-reproductive-tract-development
#8
Stanley J Robboy, Takeshi Kurita, Laurence Baskin, Gerald R Cunha
We present a detailed review of the embryonic and fetal development of the human female reproductive tract utilizing specimens from the 5th through the 22nd gestational week. Hematoxylin and eosin (H&E) as well as immunohistochemical stains were used to study the development of the human uterine tube, endometrium, myometrium, uterine cervix and vagina. Our study revisits and updates the classical reports of Koff (1933) and Bulmer (1957) and presents new data on development of human vaginal epithelium. Koff proposed that the upper 4/5ths of the vagina is derived from Müllerian epithelium and the lower 1/5th derived from urogenital sinus epithelium, while Bulmer proposed that vaginal epithelium derives solely from urogenital sinus epithelium...
August 11, 2017: Differentiation; Research in Biological Diversity
https://www.readbyqxmd.com/read/28917585/total-urogenital-sinus-mobilization-for-ambiguous-genitalia
#9
Vinicius Menezes Jesus, Francisco Buriti, Rodrigo Lessa, Maria Betânia Toralles, Luciana Barros Oliveira, Ubirajara Barroso
INTRODUCTION: Genital ambiguity is a very common phenomenon in disorders of sex development (DSD). According to the Chicago Consensus 2006, feminizing genitoplasty, when indicated, should be performed in the most virilized cases (Prader III to V). Advances in the knowledge of genital anatomy in DSD have enabled the development and improvement of various surgical techniques. Mobilization of the urogenital sinus (MUS), first described by Peña, has become incorporated by most surgeons. However, the proximity of the urethral sphincter prompts concern over urinary incontinence, especially for full mobilization of the urogenital sinus...
August 24, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28915489/clinical-features-and-surgical-procedures-of-congenital-vaginal-atresia-a-retrospective-study-of-67-patients
#10
Zhihong Xie, Xiaoping Zhang, Ningzhi Zhang, Hong Xiao, Yongying Liu, Jiandong Liu, Lili Chen, Liang Li, Linlin Zhang, Youguo Zhang
OBJECTIVE: To explore the characteristics of congenital vaginal atresia, further improve its classification, and therefore help the clinical diagnosis and treatment of congenital vaginal atresia. METHODS: This was a retrospective study of 67 patients with congenital vaginal atresia (from March 1984 to March 2015). Clinical and surgical characteristics were analyzed. RESULTS: For lower vaginal atresia, 25 patients successfully underwent vaginoplasty at the lower portion of the vagina...
August 18, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28915448/the-composition-of-the-vaginal-microbiome-in-first-trimester-pregnant-women-influences-the-level-of-autophagy-and-stress-in-vaginal-epithelial-cells
#11
Dimitrios Nasioudis, Larry J Forney, G Maria Schneider, Karol Gliniewicz, Michael T France, Allison Boester, Mio Sawai, Jessica Scholl, Steven S Witkin
Epithelial cells lining the vagina are major components of genital tract immunity. The influence of the vaginal microbiome on properties of host epithelial cells is largely unexplored. We evaluated whether differences in the most abundant lactobacilli species or bacterial genera in the vagina of first trimester pregnant women were associated with variations in the extent of stress and autophagy in vaginal epithelial cells. Vaginal swabs from 154 first trimester pregnant women were analyzed for bacterial composition by amplification and sequencing of the V1-V3 region of bacterial 16S rRNA genes...
September 8, 2017: Journal of Reproductive Immunology
https://www.readbyqxmd.com/read/28914702/digitation-to-void-what-is-the-significance-of-this-symptom
#12
Ismael Ortega, Nishamini Subramaniam, Talia Friedman, Friyan Turel, Hans Peter Dietz
OBJECTIVE: Digitation to void is defined as the need to apply manual pressure on the perineum or the vagina to assist with voiding. It has been associated with prolapse; however, there is little objective data concerning this symptom. Our aim was to determine the correlation between digitation to void, symptoms and signs of pelvic organ prolapse (POP), and urodynamic data. METHODS: This was a retrospective study that included a total of 1174 patients seen at a tertiary urogynecological unit...
September 13, 2017: Female Pelvic Medicine & Reconstructive Surgery
https://www.readbyqxmd.com/read/28913836/female-reproductive-system-morphology-of-crab-eating-fox-cerdocyon-thous-and-cryopreservation-of-genetic-material-for-animal-germplasm-bank-enrichment
#13
L C Machado, K C S Roballo, F S Cury, C E Ambrósio
The sprawl of the urbanization and road network process without building ecological corridors contributes to the high mortality rates and a threat to the population decline of wild species such as the crab-eating fox. A strategy for the ex situ conservation is the study of the reproductive biology of the species and cryopreservation of their genetic heritage through the formation of an animal germplasm bank. This research is in accordance with the principles adopted by Brazilian College of Animal Experimentation...
September 15, 2017: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/28913123/true-management-of-obstructed-hemi-vagina-and-ipsilateral-renal-anomaly-syndrome
#14
Betül Yakıştıran, Yavuz Emre Şükür, Batuhan Turgay, Cem Atabekoğlu
Herlyn-Werner-Wunderlich syndrome is an unusual congenital anomaly of the female genitourinary system, which is described as uterine didelphys with Obstructed Hemi-vagina and Ipsilateral Renal Anomaly (OHIRA), also known as OHVIRA syndrome. Typical symptoms are pelvic pain, tenderness, pelvic mass due to blood collection in the obstructed hemi-vagina and uterus, and dysmenorrhea that usually begins shortly after menarche. Clinical suspicion is very important for diagnosis and correct management avoids both short- and long-term complications...
December 2016: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28893003/spectrum-of-mri-appearance-of-mayer-rokitansky-kuster-hauser-mrkh-syndrome-in-primary-amenorrhea-patients
#15
Deb Kumar Boruah, Shantiranjan Sanyal, Bidyut Bikash Gogoi, Kangkana Mahanta, Arjun Prakash, Antony Augustine, Sashidhar Achar, Hiranya Baishya
INTRODUCTION: Mayer-Rokitansky-Kuster-Hauser (MRKH) synd-rome is a malformation in female genital tract due to interrupted embryonic development of para-mesonephric ducts leading to uterine and proximal vagina aplasia or hypoplasia. AIM: To analyse the MRI findings in females suspected of MRKH syndrome in a primary amenorrhea workup. MATERIALS AND METHODS: A cross-sectional study comprising of 11 patients of MRKH syndrome presented in a tertiary care centre from March 2016 to February 2017 evaluated in 1...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28892983/transient-thyrotoxicosis-in-molar-pregnancy
#16
Samarth Virmani, Sujatha B Srinivas, Rama Bhat, Raghavendra Rao, Ranjini Kudva
Molar pregnancy is one of the components of a broader spectrum of diseases known as Gestational Trophoblastic Disease (GTD), presenting with amenorrhoea and irregular bleeding which may be rarely associated with passage of vesicles per vagina. However, it can rarely be associated with hyperthyroidism, which may be associated with clinical features of hyperthyroidism. The following is a report of a 20-year-old woman who presented with amenorrhea followed by irregular bleeding per vagina, thyromegaly and abnormal levels of thyroid hormones...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28889719/-two-cases-of-urethral-clear-cell-adenocarcinoma-with-suspected-recurrence-of-uterine-cancer
#17
Masato Okuno, Yuji Kusuda, Isao Taguchi, Gaku Kawabata
Herein, we report two cases of urethral clear cell carcinoma in two patients who had previously undergone radical hysterectomyfor utetine cancer. Case 1 presented with bloodyvaginal discharge and case 2 presented with acute urinaryretention. Magnetic resonance imaging revealed a periurethral tumor in both cases. Both cases were suspected to be recurrence at first. However, pathological findings of the transurethral resection-biopsyshowed clear cell adenocarcinoma in both cases. Subsequentlyradical cystourethrectomy and pelvic lymphadenectomy were performed in both cases...
August 2017: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/28888700/surgical-repair-of-rectovaginal-fistula-using-the-modified-martius-procedure-a-step-by-step-guide
#18
Dan Wang, Juan Chen, Lan Zhu, Mingchen Sang, Fan Yu, Qing Zhou
STUDY OBJECTIVE: to demonstrate the surgical repair of rectovaginal fistula by the modified Martius procedure. DESIGN: step by step presentation of the procedure using video. SETTING: Rectovaginal fistula (RVF) is abnormal epithelialized connections between the vagina and rectum. Causes of rectovaginal fistula include obstetrical trauma, Crohn disease, pelvic irradiation and postsurgical complications. Many surgical interventions have been developed, from laparoscopic technique to muscle transposition and even rectal resection...
September 6, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28881431/fractional-co2-laser-of-the-vagina-for-genitourinary-syndrome-of-menopause-is-the-out-of-pocket-cost-worth-the-outcome-of-treatment
#19
Patrick Lang, Jeffrey R Dell, Leonard Rosen, Peter Weiss, Mickey Karram
OBJECTIVES: The purpose of this study is to assess patient's satisfaction treatment outcomes and out-of-pocket expense for the fractional CO2 laser (SmartXide) in the treatment of genitourinary symptoms of menopause (GSM). MATERIALS AND METHODS: A multicenter retrospective cohort study of patients who completed a course of three vaginal treatments with the SmartXide(11) Fractional CO2 laser. Patients contacted via telephone and asked to participate in questionnaires to evaluate for adverse outcomes since last treatment, symptom severity before and after treatment, patient satisfaction with treatment, patient satisfaction with out-of-pocket expense, and sexual function...
September 7, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28877731/hypoluteoidism-in-a-dog-associated-with-recurrent-mammary-fibroadenoma-stimulated-by-progestin-therapy
#20
Maria Teresa Zedda, Luisa Bogliolo, Elisabetta Antuofermo, Laura Falchi, Federica Ariu, Giovanni Pietro Burrai, Salvatore Pau
BACKGROUND: Hypoluteoidism in the bitch is characterized by insufficient production and secretion of progesterone by the corpora lutea. It is a rare pathologic condition and during pregnancy, it leads to embryonic resorption or fetal abortion. Supplementary therapy with progestins is indicated during pregnancy to obtain delivery of vital puppies but unwarranted side effects of such treatment are poorly documented. CASE PRESENTATION: A 4-year-old, nulliparous, female Istrian Shorthaired Hound dog had been mated repeatedly in six heats with different dogs of proven fertility but signs of pregnancy did not develop...
September 6, 2017: Acta Veterinaria Scandinavica
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