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https://www.readbyqxmd.com/read/28528279/first-validation-of-the-gout-activity-score-against-gout-impact-scale-in-a-primary-care-based-gout-cohort
#1
Jonathan La-Crette, Wendy Jenkins, Gwen Fernandes, Ana M Valdes, Michael Doherty, Abhishek Abhishek
OBJECTIVES: To validate the gout activity score (GAS) against the gout impact scale in a primary care based gout cohort. METHODS: This was a single-centre cross-sectional study. People with gout who participated in previous research at Academic Rheumatology, University of Nottingham, UK, and consented for participation in future studies were mailed a questionnaire in September 2015. Those returning completed questionnaires were invited to attend for a study visit at which blood was collected and musculoskeletal examination was performed...
May 17, 2017: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/28528209/parental-monitoring-among-young-men-who-have-sex-with-men-associations-with-sexual-activity-and-hiv-related-sexual-risk-behaviors
#2
Brian C Thoma
PURPOSE: Young men who have sex with men (YMSM) are at disproportionate risk for HIV infection. Parental monitoring is protective against adolescent sexual risk behavior among heterosexual adolescents, yet it is unclear whether these findings generalize to YMSM. YMSM experience unique family dynamics during adolescence, including coming out to parents and parental rejection of sexual orientation. The present study examined how theoretically derived parental monitoring constructs were associated with sexual activity and sexual risk behaviors among YMSM...
May 17, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28528142/per-and-polyfluoroalkyl-substances-pfas-in-american-red-cross-adult-blood-donors-2000-2015
#3
Geary W Olsen, David C Mair, Cleston C Lange, Laura M Harrington, Timothy R Church, Corinne L Goldberg, Ross M Herron, Hank Hanna, John B Nobiletti, Jorge A Rios, William K Reagen, Carol A Ley
In 2015, thirteen per- and polyfluoroalkyl substances (PFAS), including perfluorohexanesulfonate (PFHxS), perfluorooctanesulfonate (PFOS), perfluorooctanoate (PFOA), perfluorononanoate (PFNA), and perfluorodecanoate (PFDA) were analyzed in human plasma that was collected from a total of 616 American Red Cross male and female blood donors (ages 20-69) at 6 regional blood collection centers. Plasma samples were analyzed using a validated solvent precipitation-isotope dilution direction-liquid chromatography tandem mass spectrometry method...
May 17, 2017: Environmental Research
https://www.readbyqxmd.com/read/28527844/evaluation-of-various-pretreatments-to-fiber-post-on-the-push-out-bond-strength-of-root-canal-dentin
#4
Ömer Kırmalı, Özlem Üstün, Alper Kapdan, Alper Kuştarcı
INTRODUCTION: The aim of this in vitro study was to compare the effect of different pretreatments (fiber post) with the laser-activated irrigation (LAI) technique (for removal of the smear layer) on root canal dentin in terms of push-out bond strength (PBS) in a fiber post. METHODS: Fifty freshly extracted mandibular single-rooted premolars were prepared, and LAI was applied to all roots (17% EDTA was 5 mL for 120 seconds with an erbium, chromium:yttrium-scandium-gallium-garnet laser [0...
May 17, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28527205/moderate-physical-activity-is-associated-with-cerebral-glucose-metabolism-in-adults-at-risk-for-alzheimer-s-disease
#5
Ryan J Dougherty, Stephanie A Schultz, Taylor K Kirby, Elizabeth A Boots, Jennifer M Oh, Dorothy Edwards, Catherine L Gallagher, Cynthia M Carlsson, Barbara B Bendlin, Sanjay Asthana, Mark A Sager, Bruce P Hermann, Bradley T Christian, Sterling C Johnson, Dane B Cook, Ozioma C Okonkwo
The objective of this study was to investigate the relationship between accelerometer-measured physical activity (PA) and glucose metabolism in asymptomatic late-middle-aged adults. Ninety-three cognitively healthy late-middle-aged adults from the Wisconsin Registry for Alzheimer's Prevention participated in this cross-sectional study. They underwent 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging and wore an accelerometer (ActiGraph GT3X+) to measure free-living PA. Accelerometer data yielded measures of light (LPA), moderate (MPA), and vigorous (VPA) intensity PA...
May 17, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28527183/analytical-methods-in-tracing-honey-authenticity
#6
Jelena Trifković, Filip Andrić, Petar Ristivojević, Etil Guzelmeric, Erdem Yesilada
Honey is a precious natural product that is marketed with a wide range of nutritional and medicinal properties. However, it is also a product subjected to frequent adulteration through mislabeling and mixing with cheaper and lower-quality honeys and various sugar syrups. In that sense, honey authentication regarding its genuine botanical and geographical origins, as well as the detection of any adulteration, is essential in order to protect consumer health and to avoid competition that could create a destabilized market...
May 19, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28527044/endocytic-vesicle-rupture-is-a-conserved-mechanism-of-cellular-invasion-by-amyloid-proteins
#7
William P Flavin, Luc Bousset, Zachary C Green, Yaping Chu, Stratos Skarpathiotis, Michael J Chaney, Jeffrey H Kordower, Ronald Melki, Edward M Campbell
Numerous pathological amyloid proteins spread from cell to cell during neurodegenerative disease, facilitating the propagation of cellular pathology and disease progression. Understanding the mechanism by which disease-associated amyloid protein assemblies enter target cells and induce cellular dysfunction is, therefore, key to understanding the progressive nature of such neurodegenerative diseases. In this study, we utilized an imaging-based assay to monitor the ability of disease-associated amyloid assemblies to rupture intracellular vesicles following endocytosis...
May 19, 2017: Acta Neuropathologica
https://www.readbyqxmd.com/read/28526726/are-phloem-sieve-tubes-leaky-conduits-supported-by-numerous-aquaporins
#8
Ryan C Stanfield, Uwe G Hacke, Joan Laur
PREMISE OF THE STUDY: Aquaporin membrane water channels have been previously identified in the phloem of angiosperms, but currently their cellular characterization is lacking, especially in tree species. Pinpointing the cellular location will help generate new hypotheses of how membrane water exchange facilitates sugar transport in plants. METHODS: We studied histological sections of balsam poplar (Populus balsamifera L.) in leaf, petiole, and stem organs. Immuno-labeling techniques were used to characterize the distribution of PIP1 and PIP2 subfamilies of aquaporins along the phloem pathway...
May 19, 2017: American Journal of Botany
https://www.readbyqxmd.com/read/28526388/serum-vitamin-d-and-change-in-lipid-levels-over-5%C3%A2-y-the-atherosclerosis-risk-in-communities-study
#9
Kamil F Faridi, Di Zhao, Seth S Martin, Joshua R Lupton, Steven R Jones, Eliseo Guallar, Christie M Ballantyne, Pamela L Lutsey, Erin D Michos
OBJECTIVES: Deficiency of 25-hydroxyvitamin D (25[OH]D) is associated with increased risk for cardiovascular disease, perhaps mediated through dyslipidemia. Deficient 25(OH)D is cross-sectionally associated with dyslipidemia, but little is known about longitudinal lipid changes. The aim of this study was to determine the relationship of 25(OH)D deficiency to longitudinal lipid changes and risk for incident dyslipidemia. METHODS: This was a longitudinal community-based study of 13 039 participants from the ARIC (Atherosclerosis Risk in Communities) study who had 25(OH)D and lipids measured at baseline (1990-1992) and lipids remeasured in 1993 to 1994 and 1996 to 1998...
June 2017: Nutrition
https://www.readbyqxmd.com/read/28526382/quality-of-diet-and-level-of-physical-performance-related-to-inflammatory-markers-in-community-dwelling-frail-elderly-people
#10
Do-Yeon Kim, Chang-O Kim, Hyunjung Lim
OBJECTIVE: The aim of this study was to assess whether diet quality and functional status were associated with serum levels of interleukin (IL)-6 and tumor necrosis factor (TNF)-α in frail, elderly, community-dwelling individuals. METHODS: Seventy-eight frail, elderly individuals (age ≥65 y, usual gait speed <0.6 m/s and Mini Nutritional Assessment <24) participated in this cross-sectional study from the National Home Healthcare Services in Gangbuk-gu, Seoul, South Korea...
June 2017: Nutrition
https://www.readbyqxmd.com/read/28526363/autonomous-motivation-and-fruit-vegetable-intake-in-parent-adolescent-dyads
#11
Laura A Dwyer, Niall Bolger, Jean-Philippe Laurenceau, Heather Patrick, April Y Oh, Linda C Nebeling, Erin Hennessy
INTRODUCTION: Autonomous motivation (motivation to engage in a behavior because of personal choice, interest, or value) is often associated with health behaviors. The present study contributes to research on motivation and eating behaviors by examining (1) how autonomous motivation is correlated within parent-adolescent dyads and (2) whether parent- and adolescent-reported autonomous motivation predicts the parent-adolescent correlation in fruit and vegetable (FV) intake frequency. METHODS: Data were drawn from the Family Life, Activity, Sun, Health, and Eating (FLASHE) Study, a cross-sectional U...
June 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28526360/the-flashe-study-survey-development-dyadic-perspectives-and-participant-characteristics
#12
Linda C Nebeling, Erin Hennessy, April Y Oh, Laura A Dwyer, Heather Patrick, Heidi M Blanck, Frank M Perna, Rebecca A Ferrer, Amy L Yaroch
The National Cancer Institute developed the Family Life, Activity, Sun, Health, and Eating (FLASHE) Study to examine multiple cancer preventive behaviors within parent-adolescent dyads. The purpose of creating FLASHE was to enable the examination of physical activity, diet, and other cancer preventive behaviors and potential correlates among parent-adolescent dyads. FLASHE surveys were developed from a process involving literature reviews, scientific input from experts in the field, cognitive testing, and usability testing...
June 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28526305/cross-sectional-study-on-factors-hampering-implementation-of-measles-pre-and-postexposure-measures-in-dutch-hospitals-during-the-2013-2014-measles-outbreak
#13
L C R Fievez, A Wong, W L M Ruijs, F S Meerstadt-Rombach, A Timen
BACKGROUND: This study examined adherence to national recommendations on measles pre- and postexposure measures, including immunization of health care workers (HCWs) in Dutch hospitals, during a national outbreak of measles in The Netherlands. This study also investigated which hospital characteristics and organizational issues hamper implementation. METHODS: This was a cross-sectional survey among all general and academic hospitals in The Netherlands. An online structured questionnaire (48 questions) was administered...
May 16, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28525825/what-is-to-blame-for-postnatal-pelvic-floor-dysfunction-in-primiparous-women-pre-pregnancy-or-intrapartum-risk-factors
#14
Constantin M Durnea, Ali S Khashan, Louise C Kenny, Uliana A Durnea, James C Dornan, Suzanne M O'Sullivan, Barry A O'Reilly
BACKGROUND: The aetiology of pelvic floor dysfunction (PFD) is still poorly understood. However childbearing is recognized as a major risk factor. OBJECTIVES: To elucidate the natural history of PFD by investigating the impact of the mode of delivery on postnatal pelvic floor dysfunction in primiparas, when PFD existing before the first pregnancy is taken into consideration. STUDY DESIGN: 4P-study (Prevalence and Predictors of Pelvic floor dysfunction in Primips) is a prospective cohort study, nested within the Screening for Pregnancy Endpoints (SCOPE) study set in a tertiary referral teaching hospital with 9000 deliveries annually...
April 23, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28525196/-burnout-syndrome-among-generalist-medical-doctors-of-douala-region-cameroon-can-physical-activities-be-a-protective-factor
#15
S H Mandengue, L J Owona Manga, M Y Lobè-Tanga, P B Assomo-Ndemba, S Nsongan-Bahebege, C Bika-Lélé, F Ngo Sack, A K Njamnshi, S L Etoundi-Ngoa
BACKGROUND: This study aimed to evaluate and document the importance of Burnout syndrome among generalist medical doctors (GMD) since no investigation have been carried in Cameroon. METHODS: Cross-sectional study including 85 GMD using a self-administered questionnaire on socio-demographic characteristics, socioprofessional conditions, Maslach Burnout Inventory - Human Services Survey (MBI-HSS) to evaluate burnout, and Ricci-Gagnon physical activities level metrics...
2017: Revue Médicale de Bruxelles
https://www.readbyqxmd.com/read/28524788/state-of-global-pediatric-neurosurgery-outreach-survey-by-the-international-education-subcommittee
#16
Matthew C Davis, Brandon G Rocque, Ash Singhal, Thomas Ridder, Jogi V Pattisapu, James M Johnston
OBJECTIVE Neurosurgical services are increasingly recognized as essential components of surgical care worldwide. The degree of interest among neurosurgeons regarding international work, and the barriers to involvement in global neurosurgical outreach, are largely unexplored. The authors distributed a survey to members of the American Association of Neurological Surgeons/Congress of Neurological Surgeons (AANS/CNS) Joint Section on Pediatric Neurosurgery to assess the state of global outreach among its members and to identify barriers to involvement...
May 19, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28524628/myenteric-neuroprotective-role-of-aspirin-in-acute-and-chronic-experimental-infections-with-trypanosoma-cruzi
#17
J Y Oda, M O Belém, T M Carlos, R Gouveia, B F C Luchetti, N M Moreira, C L Massocatto, S M Araújo, D M G Sant Ana, N C Buttow, P Pinge-Filho, E J A Araújo
BACKGROUND: Experimental and clinical studies have shown that myenteric neuron cell death during infection with Trypanosoma cruzi mainly occurs in the esophagus and colon, resulting in megaesophagus and megacolon, respectively. Evidence suggests that the cyclooxygenase enzyme (COX) is involved in the T. cruzi invasion process. The use of low-dose aspirin (ASA), a COX-1/COX-2 inhibitor, has been shown to reduce infection with T. cruzi. Therefore, in this study, we evaluated the effects of treatment with low-dose ASA on myenteric colonic neurons during murine infection with T...
May 19, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28524615/correlates-of-sedentary-behaviour-in-adults-a-systematic-review
#18
REVIEW
S A Prince, J L Reed, C McFetridge, M S Tremblay, R D Reid
OBJECTIVE: The objective of this study was to systematically review evidence to identify intrapersonal, social environmental, physical environmental and policy correlates of sedentary behaviour (SB) among adults. METHODS: Six databases were searched to identify studies that reported on intrapersonal, social, physical environmental and/or policy correlates of SB across domains (i.e. occupational, leisure and transportation) in adults (mean ≥ 18 years old). Subgroup differences (sex, age, disease status, publication status and date, weekdays vs...
May 19, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28524379/the-reliability-and-validity-of-three-item-screening-measures-for-burnout-evidence-from-group-employed-health-care-practitioners-in-upstate-new-york
#19
Moira R Riley, David C Mohr, Anthony C Waddimba
We investigate the psychometric validity and reliability of three-item screening measures for emotional exhaustion, depersonalization, and personal achievement comprising an abbreviated version of the Maslach Burnout Inventory®. Despite its utilization in multiple studies, the shortened instrument has not been sufficiently validated in diverse settings, populations, and organizational contexts. We examine its ability to assess burnout accruing from patient care practice in a rural, underserved area. Utilizing data from a cross-sectional survey of 308 rural-based medical professionals, we investigate how the three short-form subscales of the nine-item abbreviated inventory compare with their gold-standard parent subscales from the original 22-item human services scale in measuring corresponding dimensions of burnout...
May 19, 2017: Stress and Health: Journal of the International Society for the Investigation of Stress
https://www.readbyqxmd.com/read/28524271/histological-characteristics-of-knee-menisci-in-patients-with-osteoarthritis
#20
D McDaniel, E Tilton, K Dominick, K Flory, T Ernest, J C Johnson, D C Main, P Kondrashov
INTRODUCTION: Existing data indicate knee menisci in patients with osteoarthritis (OA) show tearing, maceration, and fragmentation, but little is known about the change in histological structure. The aim of this study was to evaluate change in the menisci histological structure in patients with clinically diagnosed knee OA. MATERIALS AND METHODS: Fourteen patients undergoing surgical treatment of knee OA (OA group) and 14 cadaveric knees (control group) were assessed...
May 19, 2017: Clinical Anatomy
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