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https://www.readbyqxmd.com/read/30342787/the-necessity-of-conversion-from-coronary-care-unit-to-the-cardiovascular-intensive-care-unit-required-for-cardiologists
#1
REVIEW
Hiroshi Nonogi
The in-hospital mortality rate of acute myocardial infarction (AMI) has dramatically decreased due to the treatment at the coronary care unit (CCU), especially with the progress of arrhythmia therapy and reperfusion therapy. On the other hand, severe heart failure and multiple organ failure are increasing due to aging populations and multiple organ diseases. As a result, patients with AMI without complications are less likely to be admitted to the CCU, and cardiologists staying in the CCU have also decreased...
October 17, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/30342782/multidrug-resistant-bacterial-infections-in-patients-with-liver-cirrhosis-in-a-tertiary-referral-hospital
#2
Sergio Béjar-Serrano, Pablo Del Pozoe, Margarita Fernández-de la Varga, Salvador Benlloch
INTRODUCTION: Infections in cirrhotic patients caused by multidrug-resistant bacteria are currently increasing and are associated with greater morbidity and mortality. OBJECTIVES: To assess the epidemiology, risk factors and prognoses of infections caused by multidrug-resistant bacterial infections in cirrhotic patients. PATIENTS AND METHODS: Retrospective study on patients with liver cirrhosis who developed an infection during hospitalisations between July 2014 and August 2016 at our centre (Hospital Universitari i Politècnic La Fe, Valencia, Spain)...
October 17, 2018: Gastroenterología y Hepatología
https://www.readbyqxmd.com/read/30342418/creation-of-an-empiric-tool-to-predict-ecmo-deployment-in-pediatric-respiratory-or-cardiac-failure
#3
Punkaj Gupta, Jeffrey M Gossett, Danny Kofos, Mallikarjuna Rettiganti
PURPOSE: To create a real-time prediction tool to predict probability of ECMO deployment in children with cardiac or pulmonary failure. MATERIALS AND METHODS: Patients ≤18 years old admitted to an ICU that participated in the Virtual Pediatric Systems database (2009-2015) were included. Logistic regression models using adaptive lasso methodology were used to identify independent factors associated with ECMO use. RESULTS: A total of 538,202 ICU patients from 140 ICUs qualified for inclusion...
October 12, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/30340942/eculizumab-and-thrombotic-microangiopathy-after-hematopoietic-stem-cell-transplantation-a-report-on-its-efficacy-and-safety-in-two-pediatric-patients
#4
L Genere, J Bacchetta, Y Bertrand, E Javouhey, N Cheikh, A-L Sellier-Leclerc
BACKGROUND: Thrombotic microangiopathy (TMA) is a severe complication after hematopoietic stem cell transplantation (HSCT), with the reported mortality rate in such cases usually reaching 90%. CASES: We report on two pediatric cases of patients successfully treated by eculizumab for severe HSCT-TMA, occurring in two girls (8.4 and 3.6 years). The first patient developed TMA with hematologic abnormalities and renal/pulmonary lesions after allogeneic HSCT for Philadelphia-positive acute lymphoblastic leukemia; she received eculizumab 7 months after HSCT, with a dramatic improvement of renal function...
October 16, 2018: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/30340820/using-procalcitonin-to-predict-acute-kidney-injury-in-septic-patients-caveat-emptor
#5
Chih-Chung Shiao, Yu-Fang Chueh, Li Yang
No abstract text is available yet for this article.
October 16, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/30337758/-individualized-vancomycin-dosing-for-a-patient-diagnosed-as-severe-acute-pancreatitis-with-concurrent-extracorporeal-membrane-oxygenation-and-continuous-veno-venous-hemofiltration-therapy-a-case-report
#6
N He, Y Y Yan, Y Q Ying, M Yi, G Q Yao, Q G Ge, S D Zhai
Pharmacokinetic parameters can be significantly altered for acute kidney injury (AKI), extracorporeal membrane oxygenation (ECMO) and continuous veno-venous hemofiltration therapy (CVVH). Here we reported a case of individualized vancomycin dosing for a patient diagnosed as severe acute pancreatitis treated with concurrent ECMO and CVVH. A 65 kg 32-year-old woman was admitted to hospital presented with severe acute pancreatitis (SAP), respiratory failure, metabotropic acidosis and hyperkalemia. She was admitted to intensive care unit (ICU) on hospital day 1 and was initiated on CVVH...
October 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/30336782/alectinib-alecensa-induced-reversible-grade-iv-nephrotoxicity-a-case-report-and-review-of-the-literature
#7
P Ramachandran, R Morcus, M Tahir, I Onukogu, B Spinowitz, Jen C Wang
BACKGROUND: Lung cancer is among the top causes of cancer-related mortality in men and is the second most common cancer after breast cancer in women. There are approximately 234,030 new cases of lung cancer and 154,050 deaths from lung cancer in 2018 as per the latest American Cancer Society's report. Alectinib, a more potent orally active tyrosine kinase inhibitor which was approved by the US Food & Drug Administration for anaplastic lymphoma kinase-positive lung adenocarcinoma, has been shown to have a reasonable safety profile when compared with other anaplastic lymphoma kinase-targeted therapy...
October 19, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/30335269/a-rare-condition-mimicking-stroke-diabetic-uremic-encephalopathy
#8
Aysel Tekesin, Yuksel Erdal, Abdullah Soydan Mahmutoglu, Ahmet Hakyemez, Ufuk Emre
Uremic encephalopathy (UE) is a metabolic disorder associated with acute or chronic renal failure. It is characterized by the acute or subacute onset of reversible neurological symptoms and specific imaging findings. It is uncommon for uremic encephalopathy to be associated with acute bilateral lesions of the basal ganglia in diabetic uremic patients, and this can be seen most often in Asian patients. Here, we report a patient with diabetic uremic encephalopathy and bilateral basal ganglia lesions who developed acute onset dysarthria...
September 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/30335184/adaptation-and-initial-validation-of-minimum-data-set-mds-mortality-risk-index-to-mds-version-3-0
#9
Joshua D Niznik, Song Zhang, Maria K Mor, Xinhua Zhao, Mary Ersek, Sherrie L Aspinall, Walid F Gellad, Joshua M Thorpe, Joseph T Hanlon, Loren J Schleiden, Sydney Springer, Carolyn T Thorpe
OBJECTIVES: To evaluate the predictive validity of an adapted version of the Minimum Data Set (MDS) Mortality Risk Index-Revised (MMRI-R) based on MDS version 3.0 assessment items (MMRI-v3) and to compare the predictive validity of the MMRI-v3 with that of a single MDS item indicating limited life expectancy (LLE). DESIGN: Retrospective, cross-sectional study of MDS assessments. Other data sources included the Veterans Affairs (VA) Residential History File and Vital Status File...
October 18, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/30335177/defining-risk-of-general-surgery-in-patients-with-chronic-obstructive-pulmonary-diseases-copd
#10
Chao-Shun Lin, Chien-Yu Chen, Chun-Chieh Yeh, Chi-Li Chung, Ta-Liang Chen, Chien-Chang Liao
Background: The relationship between chronic obstructive pulmonary disease (COPD) and perioperative outcomes remains incompletely understood. Our purpose is to evaluate the features of postoperative adverse outcomes for geriatric surgical patients with chronic obstructive pulmonary disease (COPD) receiving non-thoracic surgeries. Methods and procedures: We conducted a nationwide study of 15,359 COPD patients aged 65 years and older who received major non-thoracic surgeries in 2008-2013 from the Taiwan National Health Insurance Research Database...
October 18, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/30334369/echocardiographic-predictors-of-worsening-renal-function-in-acute-heart-failure-observations-from-the-rashf-registry
#11
Mohammad Hossein Soltani, Mohsen Jamshir, Sepideh Taghavi, Reza Golpira, Mohsen Nasiri, Ahmad Amin, Nargeuss Abbaszade Marzbali, Nasim Naderi
AIMS: Echocardiography is known as the most useful diagnostic test in the assessment of patients with heart failure (HF), and the prognostic significance of echocardiographic findings in HF is well known. In this report, we aim to present the prognostic significance of a limited set of echocardiographic parameters obtained within 24 h of admission of patients enrolled in the Rajaie Acute Systolic Heart Failure registry. METHODS AND RESULTS: A total of 230 patients with the diagnosis of acute systolic HF (left ventricular ejection fraction ≤ 35%) were enrolled into the study...
October 18, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/30333388/a-case-series-of-acute-kidney-injury-during-anti-tuberculosis-treatment
#12
Kentaro Sakashita, Kengo Murata, Yukiko Takahashi, Miake Yamamoto, Kana Oohashi, Yu Sato, Miyako Kitazono, Akihiko Wada, Mikio Takamori
Objective The standard anti-tuberculosis (TB) regimen occasionally causes acute kidney injury (AKI). The major etiology is rifampicin-induced acute interstitial nephritis. However, the standard management of AKI induced by anti-TB drugs has yet to be established. Patients and Methods We retrospectively reviewed patients with TB who developed AKI after starting standard anti-TB treatment between 2006 and 2016 at a single TB center. The clinical characteristics and the management are described. Results Among 1,430 patients with active TB, 15 (1...
October 17, 2018: Internal Medicine
https://www.readbyqxmd.com/read/30333329/tissue-oximetry-during-cardiac-surgery-and-in-the-cardiac-intensive-care-unit-a-prospective-observational-trial
#13
Benjamin J Heller, Pranav Deshpande, Joshua A Heller, Patrick McCormick, Hung-Mo Lin, Ruiqi Huang, Gregory Fischer, Menachem M Weiner
Background: Cerebral oximetry using near-infrared spectroscopy (NIRS) has well-documented benefits during cardiac surgery. The authors tested the hypothesis that NIRS technology can be used at other sites as a tissue oximeter during cardiac surgery and in the Intensive Care Unit (ICU). Aims: To establish feasibility of monitoring tissue oximetry during and after cardiac surgery, to examine the correlations between tissue oximetry values and cerebral oximetry values, and to examine correlations between oximetry values and mean arterial pressure (MAP) in order to test whether cerebral oximetry can be used as an index organ...
October 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/30328368/health-insurance-status-and-risk-factors-of-mortality-in-patients-with-septic-acute-kidney-injury-in-ningbo-china
#14
Heng Fan, Yu Zhao, Guo-Dong Chen, Min Sun, Jian-Hua Zhu
Objective To investigate the relationship between health insurance status and outcomes of septic acute kidney injury (AKI) related hospitalizations in an intensive care unit (ICU) in Ningbo, China. Methods For this retrospective study, information was extracted from patients notes and billing records for patients >18 years of age with a diagnosis of AKI admitted to the ICU department, Ningbo First Hospital from April 2013 to March 2018. Results Of the 368 patients with sepsis admitted to ICU, 167 (45%) developed AKI; 95 patients were insured and 72 were uninsured...
October 17, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/30327686/assessment-of-renal-function-in-patients-with-myositis-and-treated-with-subcutaneous-immunoglobulin-a-series-of-24-cases
#15
Patrick Cherin, Abir Tadmouri, Christophe de Jaeger, Taylor Pindi Sala, Jean-Charles Crave
Immunoglobulin (Ig) therapy is used to treat a wide range of immunodeficiencies and autoimmune diseases; While, its clinical benefit has been demonstrated in several studies, Ig therapy is associated with a risk of systemic adverse effects. As such, Onset of renal impairment, including acute renal failure, osmotic nephrosis and renal insufficiency, after immunoglobulin administration is rare, but is one of the most significant concerns related to intravenous Ig use at immunomodulatory doses. However, only few studies have investigated the safety of subcutaneous Ig (SCIg) in relation to these rare conditions...
October 2018: Therapeutic Advances in Musculoskeletal Disease
https://www.readbyqxmd.com/read/30327278/when-long-lasting-food-selectivity-leads-to-an-unusual-genetic-diagnosis-a-case-report
#16
Prisca Da Lozzo, Andrea Magnolato, Irene Del Rizzo, Fabio Sirchia, Irene Bruno, Egidio Barbi
Hereditary fructose intolerance is an autosomal recessive disorder of fructose metabolism caused by catalytic deficiency of aldolase B enzyme [1]. The disease is typically expressed when fructose- and sucrose-containing foods are first introduced in the diet; acute manifestations include nausea, vomiting, abdominal distress, and symptomatic hypoglycemia [1,2]. Chronic fructose ingestion eventually leads to poor feeding, growth retardation and gradual liver and/or renal failure [3,4]. Some patients may remain undiagnosed until adulthood because of a self-protective avoidance of sweet tasting food that prevents the development of acute toxicity from fructose containing food; however, these subjects may suffer intermittent symptoms throughout life, leading to potentially serious misdiagnosis [4]...
October 13, 2018: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/30325464/predicting-kidney-failure-risk-after-acute-kidney-injury-among-people-receiving-nephrology-clinic-care
#17
Simon Sawhney, Monica Beaulieu, Corri Black, Ognjenka Djurdjev, Gabriela Espino-Hernandez, Angharad Marks, David J McLernon, Zainab Sheriff, Adeera Levin
Background: Outcomes after acute kidney injury (AKI) are well described, but not for those already under nephrology clinic care. This is where discussions about kidney failure risk are commonplace. We evaluated whether the established kidney failure risk equation (KFRE) should account for previous AKI episodes when used in this setting. Methods: This observational cohort study included 7491 people referred for nephrology clinic care in British Columbia in 2003-09 followed to 2016...
October 15, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/30325132/acute-renal-failure-due-to-severe-hypercalcemia-and-nephrocalcinosis-treated-with-two-doses-of-pamidronate-in-an-infant-with-williams-beuren-syndrome
#18
Funda Baştuğ, Hülya Nalçacıoğlu, Veysel Nijat Baş, Binnaz Tekatlı-Çelik, Hasan Çetinkaya, Sibel Yel
Baştuğ F, Nalçacıoğlu H, Baş VN, Tekatlı-Çelik B, Çetinkaya H, Yel S. Acute renal failure due to severe hypercalcemia and nephrocalcinosis treated with two doses of pamidronate in an infant with Williams-Beuren syndrome. Turk J Pediatr 2018; 60: 210-215. Infantile hypercalcemia has been reported in 15% of infants and children with Williams-Beuren syndrome (WBS) and has generally mild clinical symptoms. However, the need for pamidronate treatment in a few infants with severe hypercalcemia associated with WBS has been reported in literature...
2018: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/30325131/a-glue-sniffer-teenager-with-anuric-renal-failure-and-hepatitis
#19
Ali Yurtseven, Mümine Türksoylu, Pınar Yazıcı, Bülent Karapınar, Eylem Ulaş Saz
Yurtseven A, Türksoylu M, Yazıcı P, Karapınar B, Saz EU. A `glue sniffer` teenager with anuric renal failure and hepatitis. Turk J Pediatr 2018; 60: 206-209. `Inhalant abuse` is a common form of volatile drug abuse throughout the world especially in developing countries. This substance mainly contains toluene. Acute toluene inhalation produces a biphasic response with an initial central nervous system (CNS) excitation followed by CNS depression as well as various metabolic alterations. Chronic inhalational abuse is associated with muscular weakness, gastrointestinal symptoms, renal and hepatic injury...
2018: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/30324991/management-of-acute-pyelonephritis
#20
Imen Gorsane, Sana Barrah, Samia Barbouch, Hayet Kaaroud, Amel Harzallah, Taieb Ben Abdallah
INTRODUCTION: Acute pyelonephritis (APN) results from bacterial invasion of the renal parenchyma. The aim of this study was to investigate the epidemiological, clinico-biological, therapeutic and evolutionary APN and to identify the risk factors of this renal disease. METHODS: We conducted a retrospective and descriptive study, over a period of 37 years (1977-2014), including 43 patients with APN, hospitalized in our Department. RESULTS: There were 43 patients with mean age of 36...
January 2018: La Tunisie Médicale
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