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Sexual AND Dysfunction

Kitty Galiger-Dobos, Ferenc Túry
Common gynecological complications of various eating disorders include infertility, unwanted pregnancy, miscarriage, sexual dysfunction and complications in the treatment of gynecological cancers. Women with eating disorders typically see their gynecologists because of menstrual and other endocrine disorders or unexplained gastrointestinal symptoms, and often report on psychological symptoms (anxiety, depression or decreased libido). In spite of anovulation, menstruation may occur and ovulation without menstruation may be possible, which may lead to an increased incidence of unwanted pregnancies in case of prior or current eating disorders...
2018: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
Bryce B Reeve, Mian Wang, Kevin Weinfurt, Kathryn E Flynn, Deborah S Usinger, Ronald C Chen
BACKGROUND: There are multiple treatment options for men with localized prostate cancer that provide similar curative efficacy but differ in their impact on sexual functioning. AIM: To evaluate the psychometric properties of the Patient-Reported Outcomes Measurement Information System (PROMIS) Sexual Function and Satisfaction (SexFS) measures, including items from versions 1 and 2 of the short forms. METHODS: A population-based cohort of men across North Carolina completed surveys via phone interviews at baseline (prior to treatment) and at 3, 12, and 24 months after cancer treatment initiation...
December 2018: Journal of Sexual Medicine
Christina Hunter Chapman, Gerard Heath, Pamela Fairchild, Mitchell B Berger, Daniela Wittmann, Shitanshu Uppal, Anagha Tolpadi, Katherine Maturen, Shruti Jolly
PURPOSE: Following radiation therapy (RT), women with gynecologic malignancies report high rates of sexual dysfunction, but little is known regarding sexual health communication between these patients and health-care providers. This study assessed these patients' beliefs/attitudes toward providers' sexual history taking. METHODS: Surveys were administered to women who presented for follow-up care for gynecologic cancers in an academic radiation oncology department...
December 11, 2018: Journal of Cancer Research and Clinical Oncology
Aethele Khunda, Carol McCormick, Paul Ballard
INTRODUCTION AND HYPOTHESIS: Sexual function is being increasingly recognized as an important patient-reported outcome. Sacral neuromodulation (SNM) is a treatment with an expanding list of indications. The effect of sacral neuromodulation on sexual function has been examined in a number of studies with variable results. In this review, we aim to systematically review the literature and pool the data if appropriate. METHODS: The literature search was conducted primarily on the Healthcare Databases Advanced Search (HDAS) platform using the Medline, EMBASE and CINHAL search engines...
December 7, 2018: International Urogynecology Journal
Ozan Dogan, Murat Yassa
Background: Influencing factors to decide for labiaplasty are evolving and show diversity among different settings and countries. Updated underlying motivators may assist in the clinical decision-making and assessing outcomes from the patients' perspective. Objective: Herein, the main motivators of women undergoing labiaplasty and sociodemographic features are discussed. Methods: Seventy-one patients who were scheduled for labiaplasty were assessed with an open-ended, well-detailed questionnaire to determine the main motivational factors from the patients' perspective...
December 8, 2018: Aesthetic Surgery Journal
Roman Sosnowski, Jan Karol Wolski, Urszula Ziętalewicz, Michał Szymański, Robert Bakuła, Tomasz Demkow
Background: Surgery is the standard treatment for organ-restricted penile cancer, but it is also a disfiguring procedure that can profoundly affect quality of life. Using a survey, in this study we assessed the effect of different surgical invasiveness on satisfaction in selected life domains of patients who underwent penile-sparing surgery and partial penectomy. Methods: Forty patients who underwent penile-sparing surgery (n=13) or partial penectomy (n=27) were enrolled in the study. The response rate was 71%...
December 12, 2018: Sexual Health
Maciej Juryńczyk, Anu Jacob, Kazuo Fujihara, Jacqueline Palace
The field of central nervous system (CNS) inflammatory diseases has recently broadened to include a new condition associated with pathogenic serum antibodies against myelin oligodendrocyte glycoprotein (MOG). This is distinct from multiple sclerosis (MS) and aquaporin-4 (AQP4) antibody neuromyelitis optica spectrum disorders (NMOSD). MOG antibody-associated disease phenotypes are varied and range from classical neuromyelitis optica to acute demyelinating encephalomyelitis and cortical encephalitis. The diagnosis depends on using a reliable, specific and sensitive assay of the antibody...
December 8, 2018: Practical Neurology
Aida I El Makawy, Faten M Ibrahim, Dalia M Mabrouk, Kawkab A Ahmed, Mohamed Fawzy Ramadan
Sexual dysfunction in the epileptic patient is difficult to confirm whether it is ailment or therapy related. Antiepileptic drugs often use in reproductive age, through reproductive progress and maturation. On the other side, cold-pressed oils are rich in bioactive phytochemicals with health-promoting traits. The target of this work was to appraise the sexual dysfunction of antiepileptic Topiramate (TPM) and cold pressed ginger oil (CPGO) as antiepileptic alternative medicine in male mice. Fifty-four adult male albino mice were divided into nine groups (n = 6 mice)...
December 5, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Muhammetnur Tekayev, Nuray Bostancieri, Khandakar A S M Saadat, Mehmet Turker, Mehmet Yuncu, Hasan Ulusal, Hulya Cicek, Kaifee Arman
Moringa oleifera (Moringaceae) is a plant known for having high antioxidant potency, anticancer, hepatoprotective, cardioprotective etc. and many more activities. Besides these, Moringaceae has the potential for attenuating the male sexual dysfunction. Reactive oxygen species/ROS were increased in cryptorchidism and therefore cause infertility by damaging sperm DNA and germ cell apoptosis. There was an increase in heat shock proteins (HSP) in cells, which is affected by heat shock. In the present study, the antioxidant effects of two different doses of M...
December 6, 2018: Gene
Dean S Elterman, Anika R Petrella, Brandon Van Asseldonk, Leah Jamnicky, Gerald B Brock, Stacy Elliott, Antonio Finelli, Lauren M Walker, Jerzy B Gajewski, Keith A Jarvi, John Robinson, Janet Ellis, Shaun Shepherd, Hossein Saadat, Andrew Matthew
INTRODUCTION: The present descriptive analysis carried out by a pan-Canadian panel of expert healthcare practitioners (HCPs) summarizes best practices for erectile rehabilitation following prostate cancer (PCa) treatment. This algorithm was designed to support an online sexual health and rehabilitation e-clinic (SHARe-Clinic), which provides biomedical guidance and supportive care to Canadian men recovering from PCa treatment. The implications of the algorithm may be used inform clinical practice in community settings...
December 3, 2018: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Bang-Ping Jiann, Koichi Nakajima, Sonali Dighe, Chad D Harshman-Smith, Tarek A Hassan
INTRODUCTION: Management of erectile dysfunction (ED) is beset with assumptions around spontaneity of sexual intercourse, requiring candor between the physician and patient if appropriate treatment is to be implemented. AIM: To evaluate the degree to which men who take ED medications plan for and have sex. METHODS: Men from China, Japan, and Taiwan aged 40-70 years who had taken ED medications within the past 3 months were invited to participate anonymously in an online, self-administered survey that enquired about frequency and advance planning of sex, time between taking ED medication and intercourse, and treatment satisfaction...
December 3, 2018: Sexual Medicine
Maria Gouveia, Raquel Sanches, Sara Andrade, Sara Carmona, Carolina Ferreira
INTRODUCTION: Female sexual dysfunction is a common problem, affecting more than 1/3 of women during their lives. The aim of this review is to review the evidence for the effectiveness of testosterone in sexual dysfunction in postmenopausal women, particularly in the improvement of sexual desire. MATERIAL AND METHODS: The authors searched in international databases National Guidelines Clearinghouse, Guidelines Finder, Cochrane Library and MEDLINE/PubMed, for guidelines, systematic reviews, meta-analysis and randomized controlled trials, published between January 2005 and February 2017, using the MeSH terms 'testosterone', 'androgens', 'libido', 'sexual dysfunctions' and 'menopause'...
November 30, 2018: Acta Médica Portuguesa
Daniela Siqueira Prado, Rosemar Barbosa Mendes, Rosana Queiroz Gurgel, Ikaro Daniel de Carvalho Barreto, Rosana Cipolotti, Ricardo Queiroz Gurgel
OBJECTIVE: To evaluate the impact of mode of delivery on breastfeeding incentive practices and on neonatal and maternal short and long-term complications. METHODS: A cohort study was conducted between June 2015 and April 2016 with 768 puerperal women from 11 maternities in Sergipe, interviewed in the first 24 hours, 45-60 days and 6-8 months after delivery. Associations between breastfeeding incentive practices, neonatal and maternal, both short-term and late complications, and the exposure variables were evaluated by the relative risk (95%CI) and the Fisher exact test...
November 29, 2018: Revista de Saúde Pública
Mojdeh Banaei, Azam Moridi, Sareh Dashti
Introduction: Considering physical and emotional changes affecting women's sexual function in postpartum period. Aim: This study was conducted to determine the sexual dysfunction and postpartum-related factors in Bandar Abbas women in 2016. Material and Methods: This analytical cross-sectional study used systematic random sampling on 432 postpartum women referred to Bandar Abbas Healthcare Centers. Data were collected by Demographic and Obstetrics Questionnaire and Female Sexual Function Index (FSFI) Questionnaire through interview and were analyzed by using SPSS ver...
October 2018: Materia Socio-medica
Sheng-Chiang Wang, Chen-Cheng Lin, Chun-Chuan Chen, Nian-Sheng Tzeng, Yia-Ping Liu
Posttraumatic stress disorder (PTSD) is a trauma-induced mental disorder characterized by fear extinction abnormalities, which involve biological dysfunctions among fear circuit areas in the brain. Oxytocin (OXT) is a neuropeptide that regulates sexual reproduction and social interaction and has recently earned specific attention due to its role in adjusting neurobiological and behavioral correlates of PTSD; however, the mechanism by which this is achieved remains unclear. The present study aimed to examine whether the effects of OXT on traumatic stress-induced abnormalities of fear extinction (specifically induced by single prolonged stress (SPS), an animal model of PTSD) are associated with pro-inflammatory cytokines...
December 3, 2018: International Journal of Molecular Sciences
Valeria Raparelli, Marco Proietti, Andrea Lenzi, Stefania Basili
Improvements in ischemic heart disease (IHD) management have been unbalanced between sexes, with coronary microvascular dysfunction considered the likely underlying reason. The Endocrine Vascular disease Approach (EVA) is an observational study ( NCT02737982) aiming to assess sex and gender interactions between coronary circulation, sexual hormones, and platelet function. Consecutive patients with IHD undergoing coronary angiography will be recruited: (1) to assess sex and gender differences in angiographic reperfusion indexes; (2) to evaluate the effects of estrogen/androgen on sex-related differences in myocardial ischemia; (3) to investigate the platelet biology differences between men and women with IHD; (4) to verify sex- and gender-driven interplay between response to percutaneous coronary intervention, platelets, sex hormones, and myocardial damage at baseline and its impact on 12-month outcomes...
December 3, 2018: Journal of Cardiovascular Translational Research
Claudia Fernandes de Almeida Oliveira, Paulo Oliveira Dos Santos, Reinaldo Ataide de Oliveira, Hosannah Leite-Filho, Alice Fernandes de Almeida Oliveira, Gabriela Oliveira Bagano, Erivan Barbosa Lima Junior, Eduardo P Miranda, Jose de Bessa Junior, Ubirajara Barroso Junior
INTRODUCTION: Severe obesity is most effectively treated with bariatric surgery. The resulting weight loss is expected to improve a variety of obesity-related conditions, including sexual dysfunction. AIM: To analyze changes in the sexual function of women with obesity following bariatric surgery. METHODS: A prospective study was conducted between April 2015 and April 2016 involving 62 women with obesity who underwent Roux-en-Y gastric bypass...
November 30, 2018: Sexual Medicine
Natalie O Rosen, Justin P Dubé, Serena Corsini-Munt, Amy Muise
INTRODUCTION: Women diagnosed with female sexual interest/arousal disorder (FSIAD) report lower health-related quality of life, more depressive symptoms, and lower sexual and relationship satisfaction compared with healthy control subjects. Despite the impact of FSIAD on women's sexuality and the inherently interpersonal nature of the sexual problem, it remains unclear whether the partners of women with FSIAD also face negative consequences, as seen in other sexual dysfunctions. AIM: The aim of this study was to compare the sexual, relational, and psychological functioning of partners of women with FSIAD (as well as the women themselves) to their control counterparts...
November 30, 2018: Journal of Sexual Medicine
U Milenkovic, J Campbell, E Roussel, M Albersen
Erectile dysfunction is an extremely frequent and extensively studied condition, currently affecting the lives of tens of millions of men around the globe. The extensive knowledge of its pathophysiology has led to the development of phosphodiesterase 5-inhibitors, which can facilitate sexual intercourse in a large number of patients. However, an ever-increasing number of patients is unresponsive to these drugs due to underlying comorbidities or previous surgery. Different molecular pathways need to be addressed to provide treatment for a larger patient population...
December 3, 2018: Expert Opinion on Emerging Drugs
Mansooreh Yaraghi, Shirin Ghazizadeh, Fariba Mohammadi, Elahe Miri Ashtiani, Mahmood Bakhtiyari, Sayeda Mahjabeen Mareshi, Fatemeh Sadat Sarfjoo, Tahereh Eftekhar
INTRODUCTION AND HYPOTHESIS: Most patients suffering from vaginismus feel sinful, anxious, and incompetent, with reduced self-confidence. This study was aimed at comparing the effectiveness of the physiotherapy of pelvic floor muscles as a standard treatment and local injection of botulinum toxin on the sexual functioning of patients with primary vaginismus. METHODS: In this randomized clinical trial (RCT), the study population included women with primary vaginismus referred to the Sexual Health and Gynecologic Clinics of Imam Khomeini Hospital during 2013-2014...
December 1, 2018: International Urogynecology Journal
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