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https://www.readbyqxmd.com/read/30322100/implications-of-an-autism-spectrum-disorder-diagnosis-an-interview-study-of-how-physicians-experience-the-diagnosis-in-a-young-child
#1
Delphine Jacobs, Jean Steyaert, Kris Dierickx, Kristien Hens
Clinicians are significant translators and interpreters towards parents of the abundant literature on autism spectrum disorder (ASD). However, how clinicians experience and view ASD and an ASD diagnosis is not well known. Sixteen physicians working with young children with a (presumed) diagnosis of ASD participated in a semi-structured interview. They described their professional view on ASD and an ASD diagnosis, and how they experienced its use in their clinical practice. Interpretative phenomenological analysis of the data revealed two main topics about physicians' experiences: how they view ASD and an ASD diagnosis, and how they experience the implications of an ASD diagnosis...
October 12, 2018: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/30321739/development-and-validation-of-a-virtual-agent-to-screen-tobacco-and-alcohol-use-disorders
#2
Marc Auriacombe, Sarah Moriceau, Fuschia Serre, Cécile Denis, Jean-Arthur Micoulaud-Franchi, Etienne de Sevin, Emilien Bonhomme, Stéphanie Bioulac, Mélina Fatseas, Pierre Philip
BACKGROUND: Substance use disorders are under-detected and not systematically diagnosed or screened for by primary care. In this study, we present the acceptability and validity of an Embodied Conversational Agent (ECA) designed to screen tobacco and alcohol use disorder, in individuals who did not seek medical help for these disorders. METHODS: Individuals were included from June 2016 to May 2017 in the Outpatient Sleep Clinic of the University Hospital of Bordeaux...
October 6, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/30321234/association-of-visual-hallucinations-with-very-mild-degenerative-dementia-due-to-dementia-with-lewy-bodies
#3
Wei Lin, Yuan-Chang Xie, Po-Ya Cheng, Ling-Ying Dong, Guang-Uei Hung, Pai-Yi Chiu
BACKGROUND AND PURPOSE: Complex, well-formed, and detailed visual hallucinations (VHs) are among the core clinical features of dementia with Lewy bodies (DLB). We investigated the diagnostic value of VHs in different types of very mild degenerative dementia. METHODS: Participants were required to complete a structured interview form recording their basic data, clinical history, neuropsychological tests, and neuropsychiatric symptoms. Basic demographic characteristics of the participants were summarized and compared...
2018: PloS One
https://www.readbyqxmd.com/read/30321160/-limb-shaking-transitory-ischaemic-attack-in-a-patient-with-subocclusion-of-the-internal-carotid-artery
#4
A A Larionov, D A Demin, E A Kulikova, E V Nikolaeva, D A Korzh, D P Gaponov, D G Tarasov
Described in the article is a clinical case report concerning symptomatic subocclusion of the internal carotid artery in a male patient with a rare variant of recurrent limb-shaking transitory ischaemic attacks (LS-TIA). The patient presented with a three-month history of episodes of involuntary jerky movements in his left hand. These episodes occurred invariably on assuming a vertical position. The findings of duplex scanning revealed subocclusion of the right internal carotid artery. The patient was subjected to stenting with the use of the system of proximal cerebral protection...
2018: Angiologii︠a︡ i Sosudistai︠a︡ Khirurgii︠a︡, Angiology and Vascular Surgery
https://www.readbyqxmd.com/read/30320048/children-with-autism-spectrum-disorder-with-regression-exhibit-a-different-profile-in-plasma-cytokines-and-adhesion-molecules-compared-to-children-without-such-regression
#5
Antonio Gomez-Fernandez, Maria J de la Torre-Aguilar, Mercedes Gil-Campos, Katherine Flores-Rojas, Maria D Cruz-Rico, Pilar Martin-Borreguero, Juan Luis Perez-Navero
Background: In the etiopathogenesis of autism spectrum disorder (ASD), it has been suggested that a proinflammatory condition, as well as an alteration in adhesion molecules in the early stages of neurodevelopment, may play a role in the pathophysiology of the disorder. This study set out to evaluate the plasma levels of certain inflammatory cytokines, adhesion molecules, and growth factors in a sample of pediatric patients with ASD and compare them to the levels in a control group of healthy children. Methods: Fifty-four children (45 males and nine females) aged 2-6, who were diagnosed with ASD, and a control group of 54 typically-developing children of similar ages were selected...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/30319991/characterization-of-diarrheagenic-enteroaggregative-escherichia-coli-in-danish-adults-antibiotic-treatment-does-not-reduce-duration-of-diarrhea
#6
Betina Hebbelstrup Jensen, Camilla Adler Sørensen, Stig Hebbelstrup Rye Rasmussen, Dorthe Rejkjær Holm, Alice Friis-Møller, Jørgen Engberg, Hengameh C Mirsepasi-Lauridsen, Carsten Struve, Anette M Hammerum, Lone Jannok Porsbo, Randi Føns Petersen, Andreas Munk Petersen, Karen Angeliki Krogfelt
Enteroaggregative Escherichia coli (EAEC) is frequently isolated from sporadic cases of diarrhea and in outbreaks of gastroenteritis in several regions of the world. The pathophysiology of EAEC continues to be enigmatic, and the efficacy of antibiotic treatment in EAEC-associated diarrhea has been discussed. Since the level of antibiotic resistance is increasing, it is essential to restrict the use of antibiotics to prevent further resistance development. We aimed to investigate EAEC strains in adult Danish patients suffering from diarrhea and from healthy controls...
2018: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/30319464/hidden-drug-abuse-in-hong-kong-from-social-acquaintance-to-social-isolation
#7
Cherry Hau-Lin Tam, Sharon I Kwok, T Wing Lo, Sally Hing-Po Lam, Gabriel Kwun-Wa Lee
The present paper examines the issue of hidden drug abuse in Hong Kong. Although official statistics show that the reported number of drug-abuse cases has been in decline in recent years, it has been reported that drug abusers tend to hide themselves at home to take drugs; thus, they are not discovered easily by the law enforcement and social control agents who report drug abuse cases to the Central Registry of Drug Abuse, resulting in the decrease in the reported number of drug-abuse cases. This "dark figure" phenomenon is a reflection of the official figure and reporting behavior, not the actual situation of drug abuse in Hong Kong...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/30319269/patient-perspectives-on-transitioning-to-amyotrophic-lateral-sclerosis-multidisciplinary-clinics
#8
Kerri Lynn Schellenberg, Gregory Hansen
Purpose: Multidisciplinary clinics (MDC) have become the standard of care for management of amyotrophic lateral sclerosis (ALS). No studies however, have captured patients' perspectives during a transition to ALS MDCs. Recently, an ALS MDC emerged from a single-physician clinic in Saskatoon, Canada, providing patients with a unique exposure to two different models of care. Patients and methods: Fifteen patients with ALS participated in semi-structured interviews that were digitally recorded and transcribed...
2018: Journal of Multidisciplinary Healthcare
https://www.readbyqxmd.com/read/30319245/a-qualitative-study-among-breast-cancer-patients-on-chemotherapy-experiences-and-side-effects
#9
Yong Hui Nies, Adliah Mhd Ali, Norlia Abdullah, Farida Islahudin, Noraida Mohamed Shah
Purpose: The objective of this study was to explore the experiences and side-effects of breast cancer patients on chemotherapy in Malaysia. Participants and methods: Purposive sampling of 36 breast cancer patients who have completed chemotherapy and agreed to participate in semi-structured in-depth interviews. A constant comparative method and thematic analysis were used to analyze the interviews. Results: Data were categorized into six main themes: know nothing of chemotherapy; fear of chemotherapy; patients' beliefs in alternative treatments; symptom management; staying healthy after chemotherapy; and concerns of patients after chemotherapy...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/30319064/study-of-the-use-of-complementary-and-alternative-medicine-by-cancer-patients-at-kenyatta-national-hospital-nairobi-kenya
#10
Maryanne Ong'udi, Pegotty Mutai, Irene Weru
Introduction Cancer is not only a burden in the country but also a global burden with among the highest rate of mortality. In spite of the great strides made by the conventional therapy, many cancer patients have resorted to using complementary and alternative medicine (CAM) as human beings have an innate urge to try new and alternative ways to relieve their suffering. Objectives There is a need for us to establish if the cancer patients at Kenyatta National Hospital, Nairobi use CAM, to establish the socio-demographic characteristics of patients in the oncology clinic, to establish the types and patterns of CAM use, to establish the reasons and factors that may contribute to CAM use and if the primary health care provider is aware that they are using CAM...
October 14, 2018: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/30319030/tablet-based-disclosure-counselling-for-hiv-infected-children-adolescents-and-their-caregivers-a-pilot-study
#11
Megan S McHenry, Edith Apondi, Carole I McAteer, Winstone M Nyandiko, Lydia J Fischer, Ananda R Ombitsa, Josephine Aluoch, Michael L Scanlon, Rachel C Vreeman
BACKGROUND: Overwhelmed, under-trained medical staff working in resource-limited settings need efficient resources for HIV disclosure counselling. The objective of this study was to describe providers' experiences using tablet computers for disclosure-related counselling with HIV-infected children and their caregivers in western Kenya, with additional perspectives from adolescents. METHODS: A qualitative study design was implemented at three HIV clinics in western Kenya (Bumala, Busia and Port Victoria) within the Academic Model Providing Access to Healthcare (AMPATH) partnership...
October 14, 2018: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/30318953/durable-medical-equipment-reuse-and-recycling-uncovering-hidden-opportunities-for-reducing-medical-waste
#12
Anne Ordway, Jennifer S Pitonyak, Kurt L Johnson
PURPOSE: The purpose of this study was to investigate hospital practices for the management of unwanted durable medical equipment (DME) and to understand how health care providers conceived of their role in preventing DME waste. In order to fully identify opportunities for DME waste prevention, we began this study at the point where health care providers prescribed patients DME. METHODS: We conducted a basic interpretive qualitative study in a large regional health care system in the United States employing semi-structured interviews and a focus group...
October 14, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/30318848/-my-future-is-bright%C3%A2-i-won-t-die-with-the-cause-of-aids-ten-year-patient-art-outcomes-and-experiences-in-south-africa
#13
Cheryl J Hendrickson, Sophie J S Pascoe, Amy N Huber, Aneesa Moolla, Mhairi Maskew, Lawrence C Long, Matthew P Fox
INTRODUCTION: South Africa is moving into a new era of HIV treatment with "treat all" policies where people may be on treatment for most of their lives. We need to understand treatment outcomes and facilitators of long-term antiretroviral treatment (ART) adherence and retention-in-care in the South African context. In one of the first studies to investigate long-term treatment outcomes in South Africa, we aimed to describe ten-year patient outcomes at a large public-sector HIV clinic in Johannesburg and explore patient experiences of the treatment programme over this time in order to ascertain factors that may aid or hinder long-term adherence and retention...
October 2018: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/30318298/a-surgeon-led-clinically-focused-anatomy-course-increases-student-selection-of-general-surgery-as-a-career
#14
Adrian G Santini, Melanie L Korndorffer, Matthew J Barraza, Hillary R Johnson, Jamie L Kaplan, Christopher G DuCoin, Emma K Satchell, James R Korndorffer
OBJECTIVE: This study aims to identify program-specific critical factors in a student's path to general surgery and how different factors contribute to our high rate of matriculation. DESIGN: Semi-structured interviews were conducted focusing on critical factors in student's decision processes to pursue general surgery. Three investigators independently evaluated the transcripts and identified recurring themes based on phenomenological qualitative methods until saturation was achieved...
October 11, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/30317542/information-provision-for-people-with-multiple-sclerosis
#15
REVIEW
Sascha Köpke, Alessandra Solari, Anne Rahn, Fary Khan, Christoph Heesen, Andrea Giordano
BACKGROUND: People with multiple sclerosis (MS) are confronted with a number of important uncertainties concerning many aspects of the disease. These include diagnosis, prognosis, disease course, disease-modifying therapies, symptomatic therapies, and non-pharmacological interventions, among others. While people with MS demand adequate information to be able to actively participate in medical decision making and to self manage their disease, it has been shown that patients' disease-related knowledge is poor, therefore guidelines recommend clear and concise high-quality information at all stages of the disease...
October 14, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/30317070/anxiety-and-depression-in-patients-with-multiple-sclerosis-the-mediating-effects-of-perceived-social-support
#16
Audrey Henry, Ayman Tourbah, Gauthier Camus, Romain Deschamps, Laurence Mailhan, Cédric Castex, Olivier Gout, Michèle Montreuil
BACKGROUND: Social support has been identified as a buffering or intervening variable in stressful life events. Research has demonstrated that greater social support is associated with better mental health in multiple sclerosis (MS), but little is known about its links to specific aspects of mental health. We therefore investigated if and how perceived social support modulates depression, anxiety and fatigue in patients with MS. METHODS: We recruited 112 patients with MS from three French hospitals and administered a demographic and clinic interview, and self-report measures of perceived social support (Multidimensional Scale of Perceived Social Support), depression and anxiety (Hospital Anxiety and Depression Scale), and fatigue (Fatigue Severity Scale)...
October 2, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/30317016/inflammation-associated-with-volume-reduction-in-the-gray-matter-and-hippocampus-of-older-patients-with-bipolar-disorder
#17
Shang-Ying Tsai, Ariel G Gildengers, Jung-Lung Hsu, Kuo-Hsuan Chung, Pao-Huan Chen, Yu-Jui Huang
BACKGROUND: Bipolar disorder (BD) and aging appear to be associated with inflammatory activation. Inflammatory processes might affect hippocampal function, neurogenesis, and gray matter loss. This study investigated the relationship between BD-specific brain regions and the total gray matter volume, peripheral inflammatory markers, and clinical features in older patients with BD. METHODS: We recruited euthymic patients with bipolar I disorder aged ≥50 years to undergo whole-brain magnetic resonance imaging...
October 6, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/30316877/does-outpatient-cardiac-rehabilitation-help-patients-with-acute-myocardial-infarction-quit-smoking
#18
David Katz, Donna Buchanan, Mark Vander Weg, Babalola Faseru, Philip A Horwitz, Philip Jones, John A Spertus
Outpatient cardiac rehabilitation (OCR) reinforces patients' efforts to quit smoking, but the association between participation in OCR and long-term smoking status after acute myocardial infarction (AMI) is unknown. We studied hospitalized smokers with confirmed AMI from two multicenter prospective registries (PREMIER, from January 1, 2003, to June 28, 2004, and TRIUMPH, from April 11, 2005, to December 31, 2008) to describe the association of OCR participation with smoking cessation. Eligible patients smoked at least 1 cigarette per day on average in the 30 days prior to enrollment and completed 12-month follow-up (N = 1307)...
October 11, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/30316575/coping-strategies-among-colorectal-cancer-patients-undergoing-surgery-and-the-role-of-the-surgeon-in-mitigating-distress-a-qualitative-study
#19
Jonathan S Abelson, Alanna Chait, Megan Johnson Shen, Mary Charlson, Anna Dickerman, Heather Yeo
BACKGROUND: Distress is common among cancer patients and leads to worse postoperative outcomes. Surgeons are often the first physicians to have in-depth conversations with patients about a new colorectal cancer diagnosis; therefore, it is important that these surgeons understand how patients cope with the distress of a diagnosis and how they can help patients manage this distress. METHODS: Patients with colorectal cancer were recruited from an outpatient surgery clinic...
October 10, 2018: Surgery
https://www.readbyqxmd.com/read/30316490/working-from-home-an-initial-pilot-examination-of-videoconferencing-based-cognitive-behavioral-therapy-for-anxious-youth-delivered-to-the-home-setting
#20
Aubrey L Carpenter, Donna B Pincus, Jami M Furr, Jonathan S Comer
Progress in evidence-based treatments for child anxiety has been hampered by limited accessibility of quality care. This study utilized a multiple baseline design to evaluate the pilot feasibility, acceptability, and preliminary efficacy of real-time, Internet-delivered, family-based cognitive-behavioral therapy for child anxiety delivered to the home setting via videoconferencing. Participants included 13 anxious youth (mean age = 9.85) with a primary/co-primary anxiety disorder diagnosis. Eleven participants (84...
November 2018: Behavior Therapy
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