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Infection depression

Y-M Li, Y Jiang, S-D Feng, Z-H Lin
OBJECTIVE: Infection can be caused by severe burnt, trauma and hypoxia, further causing systemic inflammatory syndrome or sepsis. The sepsis occurs in about 2% of all hospitalizations and ranges from 6% to 30% in intensive care unit (ICU) in developed countries This study aimed to investigate the effects of normal lymph fluid on sepsis complicated with pulmonary injury. MATERIALS AND METHODS: Wistar rats were prepared for sepsis complicated with acute pulmonary model via cecal ligation and puncture, and received normal lymph fluid injection 60 min later...
November 2018: European Review for Medical and Pharmacological Sciences
Rose Okoyo Opiyo, Peter Suwirakwenda Nyasulu, Reuben Kamau Koigi, Anne Obondo, Dorington Ogoyi, Wambui Kogi-Makau
Background: Globally, it is known that HIV-infected pregnant women are prone to depressive symptoms. Research evidences also suggest that nutrient deficiencies may enhance the depressive illness, and that fish oil omega-3 fatty acids may alleviate the depressive symptoms. The aim of this study was to assess the effect of fish oil omega-3 eicosapentaenoic acid-rich supplements on depressive symptoms among HIV-seropositive pregnant women. Trial design: A randomized double-blinded controlled trial with two parallel groups was conducted...
2018: Annals of General Psychiatry
Rosário Serrão, Carmela Piñero, Jorge Velez, Daniela Coutinho, Fernando Maltez, Sara Lino, Rui Sarmento E Castro, Ana Paula Tares, Patrícia Pacheco, Maria João Lopes, Kamal Mansinho, Ana Cláudia Miranda, Isabel Neves, Ricardo Correia de Abreu, Joana Almeida, Leonor Pássaro
OBJECTIVES: To characterize the profile of NARC in older HIV-1-infected population and explore the factors associated with multiple NARC. METHODS: Multicenter, cross-sectional study including HIV-1-infected patients ≥50 years, virologically suppressed and on a stable ART regimen for at least 6 months. Multiple regression model explored the association of demographic and clinical variables with the number of NARC. RESULTS: Overall, 401 patients were enrolled...
October 25, 2018: International Journal of Infectious Diseases: IJID
Ellen T M Laan, Jan M Prins, Rik H W van Lunsen, Pythia T Nieuwkerk, Marian A F Nievaard-Boon
INTRODUCTION: Now that HIV infection has become a chronic disease, optimizing health status is an important goal of care for HIV-infected patients. Testosterone insufficiency (TI) can compromise health status, but little is known about the prevalence of TI and possible related factors in HIV-infected women. AIM: To investigate the prevalence of TI among HIV-infected women attending our HIV outpatient clinic, and to study the relationship between TI and sexual function, fatigue, health status, and depression...
December 3, 2018: Sexual Medicine
Hélen Francine Rodrigues, Rejane Kiyoma Furuya, Rosana Aparecida Spadoti Dantas, Alfredo José Rodrigues, Carina Aparecida Marosti Dessotte
OBJECTIVE: to investigate the associations of preoperative anxiety and depression symptoms with postoperative complications and with sociodemographic and clinical characteristics of patients submitted to the first coronary artery bypass graft. METHOD: observational, analytical and longitudinal study. A consecutive non-probabilistic sample consisted of patients submitted to coronary artery bypass graft. To evaluate the symptoms, the Hospital Anxiety and Depression Scale was used...
November 29, 2018: Revista Latino-americana de Enfermagem
Antônio Carlos Ferreira, Antônio Lúcio Teixeira, Marise Fagundes Silveira, Mariângela Carneiro
INTRODUCTION: Quality of life (QoL) is important for people living with HIV/AIDS, particularly as the disease progresses. This study evaluated the QoL of people living with HIV/AIDS (PLWHA), as well as its predictors, in one of the most impoverished regions of Brazil. METHODS: This cross-sectional study was conducted with patients older than 18 years with HIV/AIDS from two specialized HIV/AIDS care centers in the city of Montes Claros between 2013 and 2014. Sample size was calculated considering the estimates of mean scores for various dimensions of the European Portuguese version of the World Health's Organization Quality of Life Instrument in HIV Infection (WHOQOL-HIV Bref)...
November 2018: Revista da Sociedade Brasileira de Medicina Tropical
Ole Köhler-Forsberg, Liselotte Petersen, Christiane Gasse, Preben B Mortensen, Soren Dalsgaard, Robert H Yolken, Ole Mors, Michael E Benros
Importance: Infections have been associated with increased risks for mental disorders, such as schizophrenia and depression. However, the association between all infections requiring treatment and the wide range of mental disorders is unknown to date. Objective: To investigate the association between all treated infections since birth and the subsequent risk of development of any treated mental disorder during childhood and adolescence. Design, Setting, and Participants: Population-based cohort study using Danish nationwide registers...
December 5, 2018: JAMA Psychiatry
Michael Belz, Nico Rehling, Ulrike Schmidt, Jens Wiltfang, Bernhard Kis, Claus Wolff-Menzler
The prevalence of infections is supposed to be higher in older patients and to extend the length of hospital stays. This study aimed, first, to test this supposition within a large psychiatric population which we divided into four clusters of psychiatric ICD-10 diagnoses: F00-F03 (dementias), F10 (substance disorders), F20-29 (schizophrenia, schizophreniform and other non-mood psychotic disorders), F32-F33 (major depressive disorders). Second, despite the increasing evidence for the role of infections in psychiatric disorders, it is, to the best of our knowledge, largely unknown whether the rates of infections with pathogens of the four most frequent germ families differ between psychiatric diseases...
2018: PloS One
Luca Pecoraro, Lucia Martini, Franco Antoniazzi, Giorgio Piacentini, Angelo Pietrobelli
Vitamin C is an organic compound that is almost ubiquitous in the daily diet of individuals. There are clear indications of supplementation when secondary deficiency is detected related with reduced dietary intake or reduced absorption. On the other hand, indications for supplementation concerning an increased need are controversial. Several authors have studied the role of vitamin C as an adjuvant in the treatment of diseases that may affect children and adolescents. These diseases affect all organs and systems: specifically, vitamin C supplementation could play a role in respiratory, neurological, psychiatric, oncohematological, nephrological, ophthalmological and nutritional disorders...
December 4, 2018: International Journal of Food Sciences and Nutrition
N J Roberts, L Kidd, K Kirkwood, J Cross, M R Partridge
INTRODUCTION: Pulmonary rehabilitation (PR) is a core component of Chronic Obstructive Pulmonary Disease (COPD) management with well recognized benefits. While suggestions for educational content within pulmonary rehabilitation have been detailed in clinical guidance, it is unclear what educational content is delivered as part of pulmonary rehabilitation, who delivers it, and how it is delivered. METHODS: A systematic review was conducted to identify what educational content is delivered as part of pulmonary rehabilitation, how is this delivered and who delivers it...
December 2018: Respiratory Medicine
A D Irvine, A P Jones, P Beattie, S Baron, F Browne, F Ashoor, L O'Neill, A Rosala-Hallas, T Sach, C Spowart, L Taams, C Walker, M Wan, N Webb, P Williamson, C Flohr
Atopic eczema is a skin disease affecting around 20% of UK children, 16% of whom have moderate to severe disease. Severe atopic eczema can cause sleep disturbance, poor school attendance and social withdrawal, as well as attention-deficit hyperactivity disorder, anxiety and clinical depression. Skin can become infected and this can be a reason for hospital admission. Although most cases of atopic eczema can be treated with emollients, topical anti-inflammatory treatments and/or ultraviolet (UV) therapy, around 2% of children require oral (taken by mouth) immuno-suppressive treatment...
December 2018: British Journal of Dermatology
A Schmitz, R Korbel, M Rinder
In spring 2014, several wild passeriform garden birds were found severely ill or dead, all with severe periocular swellings. A blue tit (Cyanistes caeruleus) showing severe depression was humanely destroyed and sent for necropsy examination. In this bird, the lower eyelids were sagging, red and oedematous. Microscopical examination revealed marked infiltration of the eyelid tissue with fungal hyphae (stained by periodic acid-Schiff) without any inflammatory reaction. Polymerase chain reaction followed by sequencing identified Mucor racemosus and a so far unknown circovirus...
November 2018: Journal of Comparative Pathology
Hengrui Chang, Zhanle Zheng, Yiyang Yu, Jiasheng Shao, Yingze Zhang
BACKGROUND: Minimally invasive treatment of complex tibial plateau fracture represents one of the most challenging problems in orthopedic surgery. We intended to describe the percutaneous surgery involving an originally designed traction device which might facilitate the closed reduction for bicondylar tibial plateau fractures. Further, to assess the clinical outcomes of this minimally invasive technique. METHODS: Between December 2015 and July 2016, Twenty-one patients, mean age 43...
November 29, 2018: BMC Musculoskeletal Disorders
Claire Stanley, Amanda Baillargeon, Amanda Selk
OBJECTIVE: To evaluate the knowledge, attitudes, and beliefs of women during pregnancy and the postpartum period related to placentophagy. DESIGN: Mixed methods study (cross-sectional survey and online discussions). SETTING: We used social media to advertise the study to mother/parenting groups. Online discussion groups were conducted through Google Groups. PARTICIPANTS: Women during pregnancy and in the postpartum period and placenta encapsulation specialists with Internet access...
November 26, 2018: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
Andreas Baranyi, Andreas Meinitzer, Hans-Bernd Rothenhäusler, Omid Amouzadeh-Ghadikolai, Dirk V Lewinski, Robert J Breitenecker, Markus Herrmann
BACKGROUND: The aim of this study was to identify previously unrecognised biological pathways and biomarkers that might expand the inflammatory hypothesis of depression. METHODS: Broad metabolomics analyses in plasma samples from 31 chronic hepatitis C-infected patients with and without immune-related depression were carried out using the Absolute IDQ p180 kit-a targeted metabolomics approach of combined direct flow injection and liquid chromatography that measures acylcarnitines, amino acids, biogenic amines, glycerophospholipids, sphingolipids, and sugars...
2018: PloS One
(no author information available yet)
BACKGROUND: The Global Burden of Diseases, Injuries, and Risk Factors Study 2017 (GBD 2017) includes a comprehensive assessment of incidence, prevalence, and years lived with disability (YLDs) for 354 causes in 195 countries and territories from 1990 to 2017. Previous GBD studies have shown how the decline of mortality rates from 1990 to 2016 has led to an increase in life expectancy, an ageing global population, and an expansion of the non-fatal burden of disease and injury. These studies have also shown how a substantial portion of the world's population experiences non-fatal health loss with considerable heterogeneity among different causes, locations, ages, and sexes...
November 10, 2018: Lancet
Brian Veauthier, Jaime R Hornecker
Crohn's disease is a chronic inflammatory condition that affects the gastrointestinal tract. It can cause lesions from mouth to anus and may result in extraintestinal complications. The prevalence of Crohn's disease is increasing in adults and children. Genetic predispositions to Crohn's disease have been identified, and specific environmental factors have been associated with its development. Common presenting symptoms include diarrhea, abdominal pain, rectal bleeding, fever, weight loss, and fatigue. Physical examination should identify unstable patients requiring immediate care, include an anorectal examination, and look for extraintestinal complications...
December 1, 2018: American Family Physician
Anca D Petrescu, Jessica Kain, Victoria Liere, Trace Heavener, Sharon DeMorrow
The Hypothalamic-Pituitary-Adrenal (HPA) axis has an important role in maintaining the physiological homeostasis in relation to external and internal stimuli. The HPA axis dysfunctions were extensively studied in neuroendocrine disorders such as depression and chronic fatigue syndrome but less so in hepatic cholestasis, cirrhosis or other liver diseases. The HPA axis controls many functions of the liver through neuroendocrine forward signaling pathways as well as negative feedback mechanisms, in health and disease...
2018: Frontiers in Endocrinology
Lucie Dupin, Mathieu Noël, Silvère Bonnet, Albert Meyer, Thomas Géhin, Ludovic Bastide, Mialy Randriantsoa, Eliane Souteyrand, Claire Cottin, Gérard Vergoten, Jean-Jacques Vasseur, François Morvan, Yann Chevolot, Benoît Darblade
The Gram negative bacterium Pseudomonas aeruginosa (PA) is an opportunistic bacterium that causes severe and chronic infection of immune-depressed patients. It has the ability to form a biofilm that gives a selective advantage to the bacteria with respect to antibiotherapy and host defenses. Herein, we have focused on the tetrameric soluble lectin which is involved in bacterium adherence to host cells, biofilm formation, and cytotoxicity. It binds to l-fucose, d-mannose and glycan exposing terminal fucose or mannose...
November 24, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
Bérengère Dequéant, Quentin Pascal, Héloïse Bilbault, Elie Dagher, Maria-Laura Boschiroli, Nathalie Cordonnier, Edouard Reyes-Gomez
A 6-y-old neutered male ferret ( Mustela putorius furo) was presented because of a 1-mo history of progressive weight loss, chronic cough, and hair loss. On clinical examination, the animal was coughing, slightly depressed, moderately hypothermic, and had bilateral epiphora. Thoracic radiography was suggestive of severe multinodular interstitial pneumonia. Abdominal ultrasound examination revealed hepatosplenomegaly and mesenteric and pancreaticoduodenal lymphadenopathy. Fine-needle aspiration of the pancreaticoduodenal lymph node, followed by routine Romanowsky and Ziehl-Neelsen stains, revealed numerous macrophages containing myriad acid-fast bacilli, leading to identification of mycobacteriosis...
November 26, 2018: Journal of Veterinary Diagnostic Investigation
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