Read by QxMD icon Read


Ran Nivy, Alina Kaplanov, Sharon Kuzi, Michal Mazaki-Tovi, Einat Yas, Gilad Segev, Jennifer Ben-Oz, Eran Lavy, Itamar Aroch
BACKGROUND: Pancreatitis in cats (FP) has been increasingly diagnosed in recent years, but clinical studies of large numbers of affected cats are scarce. OBJECTIVES: To describe a large cohort of cats with FP requiring hospitalization. ANIMALS: One hundred and fifty-seven client-owned cats. METHODS: Retrospective study, including cats diagnosed with pancreatitis based on sonographic evidence, positive SNAP feline pancreatic lipase immunoreactivity test results, increased 1,2-o-dilauryl-rac-glycerol-glutaric Acid-(6'-methylresorufin ester)-lipase activity, histopathology, or some combination of these...
October 13, 2018: Journal of Veterinary Internal Medicine
V H Azocar, G Sepúlveda, C Ruiz, C Aguilera, E Andrés, J A Fuentealba
Kappa opioid receptors (KOR) control dopamine (DA) levels in the striatum and contribute significantly to the progression of drug addiction. Repeated exposure to psychostimulants has been associated with up-regulated KOR activity and increased DA levels in dorsal striatum. However, it has not been tested if both processes are linked. In this work, we studied if a mechanism mediated by KOR is contributing to the increase of DA levels in the dorsolateral striatum (DLS) after amphetamine (AMPH) sensitization. The AMPH sensitization was assessed after single or repeated once-a-day AMPH injections (1mg/kg)...
October 13, 2018: Journal of Neurochemistry
Birgit Stögermüller, Sigrid Ofner, Bernhard Ziegler, Christian Keller, Berthold Moser, Lukas Gasteiger
PURPOSE: The Ambu® Aura Gain™ is a new second-generation supraglottic airway device that-because of a wider curvature and a wide airway tube-allows fibreoptic intubation. The purpose of this study was to assess the oropharyngeal leak pressure of the Ambu® Aura GainTM compared with the Ambu® Aura Once™. METHODS: In this randomized non-blinded crossover trial with 50 patients aged 18 months to six years (10-20 kg), we compared the Ambu® Aura Gain™ and the Ambu® Aura Once™ for airway maintenance in anesthetized, non-paralyzed participants...
October 12, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
Amy E Vinson, Constance S Houck
PURPOSE OF REVIEW: The purpose of this review is to summarize the current evidence regarding the impact of the exposure to anesthetic and sedative agents on neurodevelopment during the period of rapid brain growth in the first 3 years of life. Though much of the definitive data demonstrating anesthesia-induced neurotoxicity has come from studies in young animals, the focus of this review is on emerging human data. RECENT FINDINGS: In 2016, the first prospective trials investigating the neurodevelopmental impact of early anesthetic exposure (GAS and PANDA studies) were published, both showing no significant impact on IQ from a single brief anesthetic...
October 13, 2018: Current Treatment Options in Neurology
H Gurbuz Aytuluk, O Aktas
Cranial nerve palsy is a rare neurological complication of epidural and subarachnoid blocks. Most of these complications are attributed to secondary intracranial hypotension due to cerebrospinal fluid leakage following dural puncture. Vocal fold paralysis (VFP) seems more likely to be overlooked and underreported due to delayed onset of symptoms and lack of attribution of dysphonia to spinal anesthesia. Therefore, VFP can often be missed and described as idiopathic. This article describes a case of VFP due to vagus nerve injury following subarachnoid block...
October 12, 2018: Der Anaesthesist
Xizhong Zhu, Liu Yang, Xiaojun Duan
Symptomatic cystic lesions of the talus are rare. The traditional operations usually do not provide visualization to reveal the deep structure of the lesion and could cause cartilage damage or other severe traumatic injury. We report an operative technique to reach the cystic lesion without talar cartilage damage, remove the lesion, and fill defect with a bone graft assisted by anterior arthroscopy and evaluate its safety and reliability for future study. Seven cases of talar bone cyst were included. The patients were placed in the supine position after anesthesia induction and noninvasive ankle traction was applied...
October 9, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
Ian J Barbash
No abstract text is available yet for this article.
October 9, 2018: Mayo Clinic Proceedings
Timothy H Mungroop, Bart F Geerts, Denise P Veelo, Timothy M Pawlik, Aurélie Bonnet, Mickaël Lesurtel, Koen M Reyntjens, Takehiro Noji, Chao Liu, Eduard Jonas, Christopher L Wu, Eduardo de Santibañes, Mohammed Abu Hilal, Markus W Hollmann, Marc G Besselink, Thomas M van Gulik
BACKGROUND: Fluid and pain management during liver surgery (eg, low central venous pressure) is a classic topic of controversy between anesthesiologists and surgeons. Little is known about practices worldwide. The aim of this study was to assess perioperative practices in liver surgery among and between surgeons and anesthesiologists worldwide that could guide the design of future international studies. METHODS: An online questionnaire was sent to 22 societies, including 4 international hepatopancreatobiliary societies, the American Society of Anesthesiologists, and 17 other (inter-)national societies...
October 9, 2018: Surgery
Bon Sung Koo, Woo Bin Kang, Jun Woo Park, So Jeong Lee, Mi Soon Lee, A Na Cho, Yang Hoon Chung, Joon Ho Lee, Yong Ik Kim, Won Seok Chae
A caudal epidural block involves placing a needle through the sacral hiatus and delivering medication into the epidural space. The procedure is safe and simple, but failure rates can be as high as 25%. The purpose of this study was to investigate the success rate of caudal epidural block by analyzing needle placement and dye flow pattern.We retrospectively analyzed the medical records of patients who underwent caudal epidural block under spinal stenosis. A case was defined as a failure if it met at least one of the following four criteria: the epidural needle was not placed correctly inside the caudal canal; blood regurgitation or aspiration in the needle was observed; the contrast dye was injected into a blood vessel; or a large amount of the dye leaked into the sacral foramen or did not reach the L5-S1 level...
October 2018: Medicine (Baltimore)
Eun-Su Choi, Young-Tae Jeon, Hye-Min Sohn, Dong-Woo Kim, Seok-Jun Choi, Chi-Bum In
BACKGROUND: Optic nerve sheath diameter (ONSD) is a well-known surrogate marker for intracranial pressure during robot-assisted laparoscopic radical prostatectomies (RALP). ONSD during RALP is known to increase due to elevated intracranial pressure as a result of the steep Trendelenburg position and carbon dioxide pneumoperitoneum. We aimed to compare the effects of total intravenous anesthesia (TIVA) and desflurane anesthesia (DES) on ONSD during RALP. METHODS: Patients scheduled for RALP were enrolled and randomly assigned to the TIVA (propofol and remifentanil) or DES (desflurane and remifentanil) group in this randomized trial...
October 2018: Medicine (Baltimore)
Joanna Jackowska, Hanna Klimza, Natalia Zagozda, Marc Remacle, Waldemar Wojnowski, Krzysztof Piersiala, Małgorzata Wierzbicka
RATIONALE: The coincidence of an idiopathic unilateral vocal fold paresis and hereditary hemorrhagic telenagiectasia (HHT) is extremely rare and has not been described in the available literature yet. PATIENTS CONCERNS: A 55-year-old female was admitted to hospital due to acute onset of hoarseness, voice fatigue, and effort dyspnea. In the past, the patient was diagnosed with HHT and on admission presented characteristic vascular lesions in the oral cavity. She reported also experiencing a moderate epistaxis at least once per month...
October 2018: Medicine (Baltimore)
Huan Wang, Yingjie Geng, Weijian Zheng, Weiping Fang, Erwei Gu, Xuesheng Liu, Wenzhi Li
BACKGROUND: During regional anesthesia, including combined spinal and epidural anesthesia (CSEA), patients may develop a perceptual alteration of limb position known as phantom limb syndrome (PLS). We aimed to identify factors that influence the PLS onset, to explore whether PLS predisposes to other postoperative symptoms, and to document the relationship between PLS and sensorimotor impairment during recovery. METHODS: Psychological questionnaires for anxiety and depression were completed beforehand, then multimodal tests of sensory and motor function, especially tests of proprioception, were performed regularly afterward...
October 2018: Medicine (Baltimore)
Gang Wang, Wei-Gang Cao, Tian-Lan Zhao
Tumescent anesthesia makes it feasible to perform liposuction in an office setting. There are often patients who desire extensive liposuction on approximately 30% of total body surface area, which means the potential of fluid overload. In this study, the charts of 83 patients undergoing extensive liposuction were retrospectively reviewed. The intra-operative fluid ratio was 1.66 for the extensive liposuction. There were no episodes of pulmonary edema, congestive heart failure exacerbation, or other major complications...
October 2018: Medicine (Baltimore)
Gildasio S De Oliveira, Mark C Kendall, Robert J McCarthy
INTRODUCTION: Intraoperative systemic esmolol has been shown to reduce postsurgical pain. Nonetheless, it is unknown whether the use of intraoperative systemic esmolol can improve patient-reported postsurgical quality of recovery. The main objective of the current investigation was to evaluate the effect of intraoperative esmolol on postsurgical quality of recovery. We hypothesized that patients receiving intraoperative esmolol would report better quality of postsurgical recovery than the ones receiving saline...
October 2018: Medicine (Baltimore)
Wei Dai, Maocai Tang, Kaihua He
BACKGROUND: Dexmedetomidine has been used as an adjuvanty added to local anesthetics to prolong analgesia following peripheral nerve blockade. The aim of this meta-analysis was to investigate the effect and safety of dexmedetomidine added to ropivacaine in brachial plexus block (BPB). METHODS: A search strategy was created to identify eligible randomized clinical trial (RCT) in PubMed, Embase, and The Cochrane Library (updated May, 2018). The methodologic quality for each included study was evaluated using the Cochrane Tool for Risk of Bias by 2 independent researchers...
October 2018: Medicine (Baltimore)
Yabin Zhou, Cheng Zhang, Shimeng Zhao, Qingxian Wang
RATIONALE: Traumatic hip dislocation is a common joint dislocation. Delayed reduction has been shown to increase the risk of avascular necrosis of the femoral head. Most of the traditional methods must be performed under general anesthesia or spinal anesthesia to relax hip muscles. Anesthesia will prolong the interval between the injury and the reduction. PATIENT CONCERNS: 16 patients presented with hip pain and a leg shortened, flexed, internally rotated and adducted...
October 2018: Medicine (Baltimore)
Bertrand Debono, Jean-Albert Lotterie, Jean-Christophe Sol, Philippe Bousquet, Pierre Duthil, Sylvie Monfraix, Yves Lazorthes, Jean Sabatier, Igor Latorzeff
BACKGROUND: During the past decades, stereotactic radiosurgery (SRS) and Gamma Knife in particular have proven its safety and efficacy for drug-resistant classical trigeminal neuralgia (CTN). However, few large series exist using linear accelerator (LINAC), reporting long-term follow-up. METHODS: Between 2006 and 2015, 301 patients were treated by LINAC at our institution. Prescribed radiation dose was 90 Gy at the far anterior target. Clinical response was defined using the BNI scale...
October 9, 2018: World Neurosurgery
Chun-Yu Chen, Yung-Fong Tsai, Wei-Ju Huang, Chang Shih-Hsin, Tsong-Long Hwang
Critically ill patients have a high risk of sepsis. Various studies have demonstrated that propofol has anti-inflammatory effects that may benefit critically ill patients who require anesthesia. However, the mechanism and therapeutic effect remain incompletely understood. Our previous data suggest that propofol can act as a formyl peptide receptor 1 (FPR1) antagonist. Here, we hypothesize that propofol mitigates sepsis-induced acute lung injury (ALI) by inhibiting mitochondria-derived N-formyl peptide-mediated neutrophil activation...
October 9, 2018: Free Radical Biology & Medicine
Hong Gao, Willian S Korim, Song T Yao, Cheryl M Heesch, Andrei V Derbenev
KEY POINTS: To maintain appropriate blood flow to various tissues of the body under a variety of physiological states, autonomic nervous system reflexes regulate regional sympathetic nerve activity and arterial blood pressure. Our data in anesthetized rats revealed that glycine released in the RVLM plays a critical role in maintaining arterial baroreflex sympathoinhibition. Manipulation of brainstem nuclei with known inputs to the RVLM (NTS and CVLM) unmasked tonic glycinergic inhibition in the RVLM...
October 12, 2018: Journal of Physiology
Joseph A Lombardo, Matthew V Macellaio, Bing Liu, Stephanie E Palmer, Leslie C Osborne
Behavioral states marked by varying levels of arousal and attention modulate some properties of cortical responses (e.g. average firing rates or pairwise correlations), yet it is not fully understood what drives these response changes and how they might affect downstream stimulus decoding. Here we show that changes in state modulate the tuning of response variance-to-mean ratios (Fano factors) in a fashion that is neither predicted by a Poisson spiking model nor changes in the mean firing rate, with a substantial effect on stimulus discriminability...
October 12, 2018: PLoS Computational Biology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"