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https://www.readbyqxmd.com/read/30517856/optical-clearing-in-the-kidney-reveals-potassium-mediated-tubule-remodeling
#1
Turgay Saritas, Victor G Puelles, Xiao-Tong Su, James A McCormick, Paul A Welling, David H Ellison
Distal nephron remodeling contributes to the pathophysiology of many clinically relevant scenarios, including diuretic resistance and certain Mendelian disorders of blood pressure. However, constitutive genetic disruptions are likely to have substantial developmental effects in this segment, and whether tubule remodeling upon physiological stimuli is a normal homeostatic mechanism is not known. Since the distal nephron acts as a potassium sensor, we assessed proliferation and tubule length in three dimensions upon dietary or inducible genetic manipulation by using optical clearing of adult mouse kidneys, whole-mount immunolabeling, and advanced light microscopy...
December 4, 2018: Cell Reports
https://www.readbyqxmd.com/read/30517574/influence-of-support-surfaces-on-the-distribution-of-body-interface-pressure-in-surgical-positioning
#2
Karoline Faria de Oliveira, Patrícia da Silva Pires, Ana Lúcia De-Mattia, Elizabeth Barichello, Cristina Maria Galvão, Cleudmar Amaral de Araújo, Maria Helena Barbosa
OBJECTIVE: to evaluate the interface pressure (IP) of support surfaces (SSs) on bony prominences. METHOD: a quasi-experimental study with repeated measures on each SS. Twenty healthy adult volunteers participated in the study. The participants were placed in the supine position on a standard operating table for evaluation of IP on the bony prominences of the occipital, subscapular, sacral, and calcaneal regions using sensors. Seven evaluations were performed for each bony prominence: one on a standard operating table, and the others on tables containing SSs made of viscoelastic polymer, soft foam, or sealed foam...
November 29, 2018: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/30516970/stretchable-conjugated-polymers-a-case-study-in-topic-selection-for-new-research-groups
#3
Andrew T Kleinschmidt, Darren J Lipomi
The field of π-conjugated (semiconducting) polymers has been underwritten largely because of the promise of flexible (and increasingly, stretchable) devices for energy and health care. Our research group has spent much of the past six years studying the mechanical properties of conjugated polymers. Mechanically robust materials can extend the life spans of devices such as solar cells and organic light-emitting diode (OLED) panels and enable high throughput processing techniques such as roll-to-roll printing...
December 5, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/30515502/highly-porous-composite-aerogel-based-triboelectric-nanogenerators-for-high-performance-energy-generation-and-versatile-self-powered-sensing
#4
Hao-Yang Mi, Xin Jing, Zhiyong Cai, Yuejun Liu, Lih-Sheng Turng, Shaoqin Gong
Boosting power generation performance while employing economical and biocompatible materials is an ongoing direction in the field of triboelectric nanogenerators (TENGs). Here, highly porous, biocompatible, cellulose nanofibril (CNF) composite-based TENGs are developed through an environmentally friendly freeze-drying approach. High tribopositivity materials, including silica fiber, human hair, and rabbit fur, are used as fillers in composite TENG fabrication for the first time to enhance the triboelectric output performance...
December 5, 2018: Nanoscale
https://www.readbyqxmd.com/read/30514869/bioinspired-and-bristled-microparticles-for-ultrasensitive-pressure-and-strain-sensors
#5
Bing Yin, Xiaomeng Liu, Hongyan Gao, Tianda Fu, Jun Yao
Biological sensory organelles are often structurally optimized for high sensitivity. Tactile hairs or bristles are ubiquitous mechanosensory organelles in insects. The bristle features a tapering spine that not only serves as a lever arm to promote signal transduction, but also a clever design to protect it from mechanical breaking. A hierarchical distribution over the body further improves the signal detection from all directions. We mimic these features by using synthetic zinc oxide microparticles, each having spherically-distributed, high-aspect-ratio, and high-density nanostructured spines resembling biological bristles...
December 4, 2018: Nature Communications
https://www.readbyqxmd.com/read/30514860/seasonal-deposition-and-lifting-of-dust-on-mars-as-observed-by-the-curiosity-rover
#6
Á Vicente-Retortillo, G M Martínez, N Renno, C E Newman, I Ordonez-Etxeberria, M T Lemmon, M I Richardson, R Hueso, A Sánchez-Lavega
In situ measurements by the Curiosity rover provide a unique opportunity for studying the effects of dust on assets placed at the surface of Mars. Here we use in situ measurements of solar UV radiation to quantify the seasonal and interannual variability of dust accumulation on the sensor on the rover deck. We show that the amount of dust accumulated on the sensor follows a seasonal cycle, with net dust removal during the perihelion season until Ls ~ 300°, and net dust deposition until the end of the aphelion season (Ls ~ 300°-180°)...
December 4, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30513979/evaluation-of-food-fineness-by-the-bionic-tongue-distributed-mechanical-testing-device
#7
Jingjing Liu, Ying Cui, Yizhou Chen, Wei Wang, Yuanyuan Tang, Hong Men
In this study, to obtain a texture perception that is closer to the human sense, we designed eight bionic tongue indenters based on the law of the physiology of mandibular movements and tongue movements features, set up a bionic tongue distributed mechanical testing device, performed in vitro simulations to obtain the distributed mechanical information over the tongue surface, and preliminarily constructed a food fineness perception evaluation model. By capturing a large number of tongue movements during chewing, we analyzed and simulated four representative tongue movement states including the tiled state, sunken state, raised state, and overturned state of the tongue...
December 3, 2018: Sensors
https://www.readbyqxmd.com/read/30513838/cuffless-blood-pressure-estimation-using-pressure-pulse-wave-signals
#8
Zeng-Ding Liu, Ji-Kui Liu, Bo Wen, Qing-Yun He, Ye Li, Fen Miao
Pulse transit time (PTT) has received considerable attention for noninvasive cuffless blood pressure measurement. However, this approach is inconvenient to deploy in wearable devices because two sensors are required for collecting two-channel physiological signals, such as electrocardiogram and pulse wave signals. In this study, we investigated the pressure pulse wave (PPW) signals collected from one piezoelectric-induced sensor located at a single site for cuffless blood pressure estimation. Twenty-one features were extracted from PPW that collected from the radial artery, and then a linear regression method was used to develop blood pressure estimation models by using the extracted PPW features...
December 2, 2018: Sensors
https://www.readbyqxmd.com/read/30513798/kinematic-and-kinetic-patterns-related-to-free-walking-in-parkinson-s-disease
#9
Martín Martínez, Federico Villagra, Juan Manuel Castellote, María A Pastor
The aim of this study is to compare the properties of free-walking at a natural pace between mild Parkinson's disease (PD) patients during the ON-clinical status and two control groups. In-shoe pressure-sensitive insoles were used to quantify the temporal and force characteristics of a 5-min free-walking in 11 PD patients, in 16 young healthy controls, and in 12 age-matched healthy controls. Inferential statistics analyses were performed on the kinematic and kinetic parameters to compare groups' performances, whereas feature selection analyses and automatic classification were used to identify the signature of parkinsonian gait and to assess the performance of group classification, respectively...
December 1, 2018: Sensors
https://www.readbyqxmd.com/read/30513634/a-sigma-delta-adc-for-signal-conditioning-ic-of-automotive-piezo-resistive-pressure-sensors-with-over-80-db-snr
#10
Behnam Samadpoor Rikan, Sang-Yun Kim, Nabeel Ahmad, Hamed Abbasizadeh, Muhammad Riaz Ur Rehman, Khuram Shehzad, Arash Hejazi, Reza E Rad, Deeksha Verma, Kang-Yoon Lee
This paper presents a second-order discrete-time Sigma-Delta (SD) Analog-to-Digital Converter (ADC) with over 80 dB Signal to Noise Ratio (SNR), which is applied in a signal conditioning IC for automotive piezo-resistive pressure sensors. To reduce the flicker noise of the structure, choppers are used in every stage of the high gain amplifiers. Besides, to reduce the required area and power, only the CIC filter structure is adopted as a decimation filter. This filter has a configurable structure that can be applied to different data rates and input signal bandwidths...
November 30, 2018: Sensors
https://www.readbyqxmd.com/read/30513592/an-implantable-sensorized-lead-for-continuous-monitoring-of-cardiac-apex-rotation
#11
Emanuela Marcelli, Laura Cercenelli
Changes in the pattern or amplitude of cardiac rotation have been associated with important cardiovascular diseases, including Heart Failure (HF) which is one of the major health problems worldwide. Recent advances in echocardiographic techniques have allowed for non-invasive quantification of cardiac rotation; however, these examinations do not address the continuous monitoring of patient status. We have presented a newly developed implantable, transvenous lead with a tri-axis (3D) MEMS gyroscope incorporated near its tip to measure cardiac apex rotation in the three-dimensional space...
November 30, 2018: Sensors
https://www.readbyqxmd.com/read/30513590/dynamic-balance-measurement-and-quantitative-assessment-using-wearable-plantar-pressure-insoles-in-a-pose-sensed-virtual-environment
#12
Cunguang Lou, Chenyao Pang, Congrui Jing, Shuo Wang, Xufeng He, Xiaoguang Liu, Lei Huang, Feng Lin, Xiuling Liu, Hongrui Wang
The center of plantar pressure (COP) reflects the dynamic balance of subjects to a certain extent. In this study, wearable pressure insoles are designed, body pose measure is detected by the Kinect sensor, and a balance evaluation system is formulated. With the designed games for the interactive actions, the Kinect sensor reads the skeletal poses to judge whether the desired action is performed, and the pressure insoles simultaneously collect the plantar pressure data. The COP displacement and its speed are calculated to determine the body sway and the ability of balance control...
November 30, 2018: Sensors
https://www.readbyqxmd.com/read/30513585/leak-detection-in-water-pipes-using-submersible-optical-optic-based-pressure-sensor
#13
Leslie Wong, Ravin Deo, Suranji Rathnayaka, Benjamin Shannon, Chunshun Zhang, Wing Kong Chiu, Jayantha Kodikara, Hera Widyastuti
Leakage is undesirable in water distribution networks, as leaky pipes are financially costly both to water utilities and consumers. The ability to detect, locate, and quantify leaks can significantly improve the service delivered. Optical fibre sensors (OFS) have previously demonstrated their capabilities in performing real-time and continuous monitoring of pipe strength leak detection. However, the challenge remains due to the high labour cost and time-consuming process for the installation of optical fibre sensors to existing buried pipelines...
November 30, 2018: Sensors
https://www.readbyqxmd.com/read/30511345/evaluation-of-a-new-catheter-for-simultaneous-intracranial-pressure-monitoring-and-cerebral-spinal-fluid-drainage-a-pilot-study
#14
Xiuyun Liu, Lara L Zimmermann, Nhi Ho, Paul Vespa, Xiaoling Liao, Xiao Hu
OBJECTIVES: Intracranial pressure (ICP) monitoring is a common practice when treating intracranial pathology with risk of elevated ICP. External ventricular drain (EVD) insertion is a standard approach for both monitoring ICP and draining cerebrospinal fluid (CSF). However, the conventional EVD cannot serve these two purposes simultaneously because it cannot accurately measure ICP and its pulsatile waveform while the EVD is open to CSF drainage. A new Integra® Camino® FLEX Ventricular Catheter (Integra Lifesciences, County Offaly, Ireland) with a double-lumen construction has been recently introduced into the market, and it can monitor ICP waveforms even during CSF drainage...
December 3, 2018: Neurocritical Care
https://www.readbyqxmd.com/read/30507152/a-highly-compressible-crosslinked-polyacrylamide-hydrogel-enabled-compressible-zn-mno2-battery-and-a-flexible-battery-sensor-system
#15
Zifeng Wang, Funian Mo, Longtao Ma, Qi Yang, Guojin Liang, Zhuoxin Liu, Hongfei Li, Na Li, Haiyan Zhang, Chunyi Zhi
The fast advancement in flexible and wearable electronics has put up with new requirements on the energy storage device with improved tolerance to deformation apart from offering power output. Despite the tremendous progress in stretchable energy storage devices, the compressional energy storage devices have indeed received limited research attention. In this work, an intrinsically compressible rechargeable battery was proposed using the Zn-MnO2 chemistry and a crosslinked polyacrylamide (PAAm) hydrogel electrolyte...
December 3, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/30505569/global-satellite-retrievals-of-the-near-surface-atmospheric-vapor-pressure-deficit-from-amsr-e-and-amsr2
#16
Jinyang Du, John S Kimball, Rolf H Reichle, Lucas A Jones, Jennifer D Watts, Youngwook Kim
Near-surface atmospheric Vapor Pressure Deficit (VPD) is a key environmental variable affecting vegetation water stress, evapotranspiration, and atmospheric moisture demand. Although VPD is readily derived from in situ standard weather station measurements, more spatially continuous global observations for regional monitoring of VPD are lacking. Here, we document a new method to estimate daily (both a.m. and p.m.) global land surface VPD at a 25-km resolution using a satellite passive microwave remotely sensed Land Parameter Data Record (LPDR) derived from the Advanced Microwave Scanning Radiometer (AMSR) sensors...
2018: Remote Sensing
https://www.readbyqxmd.com/read/30503993/to-eat-or-to-sleep-that-is-a-lateral-hypothalamic-question
#17
REVIEW
Elda Arrigoni, Melissa J S Chee, Patrick M Fuller
The lateral hypothalamus (LH) is a functionally and anatomically complex brain region that is involved in the regulation of many behavioral and physiological processes including feeding, arousal, energy balance, stress, reward and motivated behaviors, pain perception, body temperature regulation, digestive functions and blood pressure. Despite noteworthy experimental efforts over the past decades, the circuit, cellular and synaptic bases by which these different processes are regulated by the LH remains incompletely understood...
November 29, 2018: Neuropharmacology
https://www.readbyqxmd.com/read/30503172/-na-increases-in-body-fluids-sensed-by-central-na-x-induce-sympathetically-mediated-blood-pressure-elevations-via-h-dependent-activation-of-asic1a
#18
Kengo Nomura, Takeshi Y Hiyama, Hiraki Sakuta, Takashi Matsuda, Chia-Hao Lin, Kenta Kobayashi, Kazuto Kobayashi, Tomoyuki Kuwaki, Kunihiko Takahashi, Shigeyuki Matsui, Masaharu Noda
Increases in sodium concentrations ([Na+ ]) in body fluids elevate blood pressure (BP) by enhancing sympathetic nerve activity (SNA). However, the mechanisms by which information on increased [Na+ ] is translated to SNA have not yet been elucidated. We herein reveal that sympathetic activation leading to BP increases is not induced by mandatory high salt intakes or the intraperitoneal/intracerebroventricular infusions of hypertonic NaCl solutions in Nax -knockout mice in contrast to wild-type mice. We identify Nax channels expressed in specific glial cells in the organum vasculosum lamina terminalis (OVLT) as the sensors detecting increases in [Na+ ] in body fluids and show that OVLT neurons projecting to the paraventricular nucleus (PVN) are activated via acid-sensing ion channel 1a (ASIC1a) by H+ ions exported from Nax -positive glial cells...
November 21, 2018: Neuron
https://www.readbyqxmd.com/read/30502250/influence-of-elevated-intra-abdominal-pressure-on-suture-tension-dynamics-in-a-porcine-model
#19
Alexander Schachtrupp, Oliver Wetter, Jörg Höer
BACKGROUND: Inadequate suture tension is a risk factor for the failure of laparotomy closure. Suture tension dynamics in the abdominal wall are still obscure due to the lack of measuring devices. To answer the questions if intra-abdominal hypertension (IAH) influences suture tension in midline laparotomies and if IAH leads to a permanent loss of suture tension, microsensors were applied in a porcine model of IAH. MATERIAL AND METHODS: Microsensors measuring suture tension "on the thread" with a frequency of 1/s were developed and implanted in the suture lines of midline laparotomies in four pigs...
January 2019: Journal of Surgical Research
https://www.readbyqxmd.com/read/30499944/optical-detection-of-ultrasound-by-lateral-shearing-interference-of-a-transparent-pdms-thin-film
#20
Supannee Learkthanakhachon, Suejit Pechprasarn, Michael G Somekh
A lateral shearing interferometric technique combined with an 11.6 μm polydimethylsiloxane (PDMS) transparent thin film is proposed and demonstrated for optical detection of ultrasound. We experimentally report the device change of reflectivity with pressure of 5.1×10-7   Pa-1 , 9.5 times more sensitive than the critical-angle-based sensor, 31 times more sensitive than the surface-plasmon-based sensor, and comparable to the Fabry-Perot sensor. The objective-lens-based angle scanning characterization setup inspired from a laser scanning system allows direct comparison between the PDMS sensor and critical-angle-based sensor by adjusting the incident angle with a scanning mirror, thereby eliminating optical and electronics system dependence...
December 1, 2018: Optics Letters
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