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https://www.readbyqxmd.com/read/30537390/protein-bound-freestanding-2d-metal-film-for-stealth-information-transmission
#1
Rongrong Qin, Yongchun Liu, Fei Tao, Chen Li, Wenfei Cao, Peng Yang
The welding and sintering of nanomaterials is usually achieved at high temperatures and high pressures. Here, it is found that merging of metal nanoparticles occurs under ambient conditions in an aqueous solution via protein bonding. It is discovered that the silver nanoparticles from the in situ reduction of silver ammonium ions by glucose undergo confined nucleation and growth and are bound by ultrathin amyloid-like β-sheet stacking of lysozyme. This merging of silver nanoparticles creates a freestanding large-area (e...
December 9, 2018: Advanced Materials
https://www.readbyqxmd.com/read/30531375/patterns-of-heat-strain-among-a-sample-of-u-s-underground-miners
#2
Kristin Yeoman, Weston DuBose, Timothy Bauerle, Tristan Victoroff, Seth Finley, Gerald Poplin
OBJECTIVE: This study characterizes physiological measures of heat exposure among U.S. underground miners. METHODS: Core body temperature measured by using ingestible sensors during subjects' normal work shifts was categorized into four temperature zones: <37.5°C, 37.5°C to <38°C, 38°C to <38.5°C, and ≥38.5°C. RESULTS: On average, subjects changed temperature zones 13.8 times per shift. Temperatures increased above the recommended limit of 38°C nearly 5 times per shift for an average of 26 minutes each episode...
December 7, 2018: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/30530707/the-novel-two-component-system-macrs-is-a-pleiotropic-regulator-that-controls-multiple-morphogenic-membrane-protein-genes-in-streptomyces-coelicolor
#3
Meng Liu, Peipei Zhang, Yanping Zhu, Ting Lu, Yemin Wang, Guangxiang Cao, Mei Shi, Xiu-Lan Chen, Meifeng Tao, Xiuhua Pang
As with most annotated two-component systems (TCSs) of Streptomyces coelicolor , the function of TCS SCO2120/2121 was unknown. Based on our findings, we have designated this TCS MacRS for <u>m</u>orphogenesis and <u>ac</u>tinorhodin regulator/sensor. Our study indicated that either single or double mutation of MacRS largely blocked production of actinorhodin but enhanced formation of aerial mycelium. Chromatin immunoprecipitation (ChIP) sequencing, using a S. coelicolor strain expressing MacR-Flag fusion protein, identified in vivo targets of MacR, and DNaseI foot-printing of these targets revealed a consensus sequence for MacR binding, TGAGTACnnGTACTCA, containing two 7-bp inverted repeats...
December 7, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/30525472/real-time-electrochemical-detection-of-pseudomonas-aeruginosa-phenazine-metabolites-using-transparent-carbon-ultramicroelectrode-arrays
#4
Olja Simoska, Marta Sans, Mignon D Fitzpatrick, Christopher M Crittenden, Livia S Eberlin, Jason B Shear, Keith J Stevenson
Here, we use a recently developed electrochemical sensing platform of transparent carbon ultramicroelectrode arrays (T-CUAs) for the in vitro detection of phenazine metabolites from the opportunistic human pathogen Pseudomonas aeruginosa. Specifically, redox-active metabolites pyocyanin (PYO), 5-methylphenazine-1-carboxylic acid (5-MCA) and 1-hydroxyphenazine (OHPHZ) are produced by P. aeruginosa, which is commonly found in chronic wound infections and in the lungs of cystic fibrosis patients. As highly diffusible chemicals, PYO and other metabolites are extremely toxic to surrounding host cells and other competing microorganisms, thus their detection is of great importance as it could provide insights regarding P...
December 10, 2018: ACS Sensors
https://www.readbyqxmd.com/read/30525418/stretchable-strain-vector-sensor-based-on-parallelly-aligned-vertical-graphene
#5
Shuang Huang, Gen He, Cheng Yang, Jiangming Wu, Chan Guo, Tian Hang, Baohong Li, Chengduan Yang, Di Liu, Hui-Jiuan Chen, Qianni Wu, Xuchun Gui, Shaozhi Deng, Yu Zhang, Fanmao Liu, Xi Xie
The development of wearable strain sensors for human-machine interface has attracted considerable research interests. Most existing wearable strain sensors were incapable of simultaneously detecting strain amplitudes and directions and they failed to fully record stretching vectors that occurred on the body. Graphene and graphene-derived materials have been utilized to construct wearable strain sensors with excellent electrical sensitivities. While the growth techniques of planner graphene and vertical graphene (VG) have been established, the fabrication of VG aligned in parallel within a larger area has not been previously achieved...
December 11, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/30525407/ultralight-superelastic-and-fatigue-resistant-graphene-aerogel-templated-by-graphene-oxide-liquid-crystal-stabilized-air-bubbles
#6
Xiaofang Zhang, Tongping Zhang, Zhi Wang, Zhongjie Ren, Shouke Yan, Yongxin Duan, Jianming Zhang
Graphene aerogel (GA) has attracted great attention due to its unique properties, such as ultralow density, superelasticity and multifunctionality. However, it is a great challenge to develop superelastic and fatigue resistant GA (SFGA) with ultralow density because it is generally contradictory to improve the mechanical properties with reducing density of GA. Herein, we report a simple and efficient approach to preparing ultralight SFGA templated by graphene oxide liquid crystal (GOLC) stabilized air bubbles...
December 10, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/30525398/hierarchical-reduced-graphene-oxide-ridges-for-stretchable-wearable-and-washable-strain-sensors
#7
Jia Song, Yinlong Tan, Zengyong Chu, Min Xiao, Gongyi Li, Zhenhua Jiang, Jing Wang, Tianjiao Hu
Recently, flexible and wearable devices are increasingly in demand and graphene has been widely used due to its exceptional chemical, mechanical and electrical properties. Building complex buckling patterns of graphene is an essential strategy to increase its flexible and stretchable properties. Herein, a facile dimensionally-controlled four-dimensional (4D) shrinking method was proposed to generate hierarchical reduced graphene oxide (rGO) buckling patterns on curved substrates mimicking different parts of the uniforms...
December 10, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/30525384/diffusion-driven-al-doping-of-zno-nanorods-and-stretchable-gas-sensors-made-of-doped-zno-nanorods-ag-nanowires-bilayers
#8
Gitae Namgung, Qui T H Ta, Woochul Yang, Jin-Seo Noh
A crystal-damage-free nano-doping method, which utilized the vacuum drive-in diffusion of Al into ZnO nanorods, was developed. In this method, vertical ZnO nanorod arrays that were grown by chemical bath deposition beforehand were deposited with Al thin film and subsequently heat-treated under a high vacuum. At an optimum condition, the surface Al atoms were completely diffused into ZnO nanorods, resulting in Al-doped ZnO nanorods. Stretchable gas sensors were fabricated by sequentially drop-casting Al-doped ZnO nanorods and silver nanowires on PDMS substrate...
December 7, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/30525143/nanostructuring-mechanical-cracks-in-a-flexible-conducting-polymer-thin-film-for-ultra-sensitive-vapor-sensing
#9
Biporjoy Sarkar, Dillip K Satapathy, Manu Jaiswal
The swelling of electrically conducting polymer films upon absorption of vapors like alcohol or moisture is widely known. However, this swelling leads to feeble changes in charge transport characteristics. We demonstrate a colossal enhancement (from ∼6% to 108%) in the vapor-induced resistance change for a representative system, poly(3,4-ethylene dioxythiophene) polystyrene sulfonate (PEDOT:PSS). This is achieved when the films are nanostructured by strain-induced quasi-periodic parallel cracks, which is then followed by crack engineering...
December 7, 2018: Nanoscale
https://www.readbyqxmd.com/read/30523681/3d-printed-graphene-pdms-composites-for-stretchable-and-strain-insensitive-temperature-sensors
#10
Zhenyu Wang, Weilian Gao, Qiang Zhang, Kaiqing Zheng, Jiawen Xu, Wei Xu, Erwei Shang, Jing Jiang, Jie Zhang, Yu Liu
Materials possessing exceptional temperature sensitivity and high stretchability are of importance for real time temperature monitoring on three-dimensional components with complex geometries, when operating under various external deformation modes. Herein, we develop a stretchable temperature sensor consisting of cellular graphene/polydimethylsiloxane (PDMS) composite. The first of its kind, graphene based polymer composites with desired micro-structures are produced through a direct 3D ink writing technique...
December 7, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/30523466/effect-of-tissue-material-properties-in-blast-loading-coupled-experimentation-and-finite-element-simulation
#11
Molly T Townsend, Eren Alay, Maciej Skotak, Namas Chandra
Computational models of blast-induced traumatic brain injury (bTBI) require a robust definition of the material models of the brain. The mechanical constitutive models of these tissues are difficult to characterize, leading to a wide range of values reported in literature. Therefore, the sensitivity of the intracranial pressure (ICP) and maximum principal strain to variations in the material model of the brain was investigated through a combined computational and experimental approach. A finite element model of a rat was created to simulate a shock wave exposure, guided by the experimental measurements of rats subjected to shock loading conditions corresponding to that of mild traumatic brain injury in a field-validated shock tube...
December 6, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/30523201/species-typing-of-nontuberculous-mycobacteria-by-use-of-deoxyribozyme-sensors
#12
Hillary N Wood, Ashelyn E Sidders, Lauren E Brumsey, Evgeny S Morozkin, Yulia V Gerasimova, Kyle H Rohde
BACKGROUND: Nontuberculous mycobacteria (NTM) species are a rising threat, especially to patients living with pulmonary comorbidities. Current point-of-care diagnostics fail to adequately identify and differentiate NTM species from Mycobacterium tuberculosis ( Mtb ). Definitive culture- and molecular-based testing can take weeks to months and requires sending samples out to specialized diagnostic laboratories. METHODS: In this proof-of-concept study, we developed an assay based on PCR amplification of 16S ribosomal RNA (rRNA) rrs genes by using universal mycobacterial primers and interrogation of the amplified fragments with a panel of binary deoxyribozyme (BiDz) sensors to enable species-level identification of NTM (BiDz-NTMST )...
December 6, 2018: Clinical Chemistry
https://www.readbyqxmd.com/read/30521678/a-simple-dnazyme-based-fluorescent-assay-for-klebsiella-pneumoniae
#13
Monsur Ali, Anatoly Splenkin, Ellena Peterson, Weian Zhao
Pathogenic bacteria pose a serious public health threat. Rapid and cost effective detection of such bacteria remains a major challenge. Here, we present a DNAzyme-based fluorescent paper sensor for Klebsiella pneumoniae. The DNAzyme was generated by an in vitro selection technique to cleave a fluorogenic DNA-RNA chimeric substrate in the presence of K. pneumoniae. The DNAzyme was printed on a paper substrate in a 96 well format to serve as mix-and-read fluorescent assay which exhibited a limit of detection (LOD) 105 CFUs/mL...
December 6, 2018: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/30516970/stretchable-conjugated-polymers-a-case-study-in-topic-selection-for-new-research-groups
#14
Andrew T Kleinschmidt, Darren J Lipomi
The field of π-conjugated (semiconducting) polymers has been underwritten largely because of the promise of flexible (and increasingly, stretchable) devices for energy and health care. Our research group has spent much of the past six years studying the mechanical properties of conjugated polymers. Mechanically robust materials can extend the life spans of devices such as solar cells and organic light-emitting diode (OLED) panels and enable high throughput processing techniques such as roll-to-roll printing...
December 5, 2018: Accounts of Chemical Research
https://www.readbyqxmd.com/read/30514869/bioinspired-and-bristled-microparticles-for-ultrasensitive-pressure-and-strain-sensors
#15
Bing Yin, Xiaomeng Liu, Hongyan Gao, Tianda Fu, Jun Yao
Biological sensory organelles are often structurally optimized for high sensitivity. Tactile hairs or bristles are ubiquitous mechanosensory organelles in insects. The bristle features a tapering spine that not only serves as a lever arm to promote signal transduction, but also a clever design to protect it from mechanical breaking. A hierarchical distribution over the body further improves the signal detection from all directions. We mimic these features by using synthetic zinc oxide microparticles, each having spherically-distributed, high-aspect-ratio, and high-density nanostructured spines resembling biological bristles...
December 4, 2018: Nature Communications
https://www.readbyqxmd.com/read/30514787/the-monothiol-glutaredoxin-grx4-regulates-iron-homeostasis-and-virulence-in-cryptococcus-neoformans
#16
Rodgoun Attarian, Guanggan Hu, Eddy Sánchez-León, Mélissa Caza, Daniel Croll, Eunsoo Do, Horacio Bach, Tricia Missall, Jennifer Lodge, Won Hee Jung, James W Kronstad
The acquisition of iron and the maintenance of iron homeostasis are important aspects of virulence for the pathogenic fungus Cryptococcus neoformans In this study, we characterized the role of the monothiol glutaredoxin Grx4 in iron homeostasis and virulence in C. neoformans Monothiol glutaredoxins are important regulators of iron homeostasis because of their conserved roles in [2Fe-2S] cluster sensing and trafficking. We initially identified Grx4 as a binding partner of Cir1, a master regulator of iron-responsive genes and virulence factor elaboration in C...
December 4, 2018: MBio
https://www.readbyqxmd.com/read/30514708/coupling-of-human-rhodopsin-to-a-yeast-signaling-pathway-enables-characterization-of-mutations-associated-with-retinal-disease
#17
Benjamin M Scott, Steven K Chen, Nihar Bhattacharyya, Abdiwahab Y Moalim, Sergey V Plotnikov, Elise Heon, Sergio G Peisajovich, Belinda S W Chang
G protein-coupled receptors (GPCRs) are crucial sensors of extracellular signals in eukaryotes, with multiple GPCR mutations linked to human diseases. With the growing number of sequenced human genomes, determining the pathogenicity of a mutation is challenging, but can be aided by a direct measurement of GPCR-mediated signaling. This is particularly difficult for the visual pigment rhodopsin, a GPCR activated by light, for which hundreds of mutations have been linked to inherited degenerative retinal diseases such as retinitis pigmentosa (RP)...
December 4, 2018: Genetics
https://www.readbyqxmd.com/read/30513652/dynamic-outlier-detection-in-the-calibration-by-comparison-method-applied-to-strain-gauge-weight-sensors
#18
Wojciech Walendziuk
The present work proposes a robust method of analyzing sets of data series shifted in time in respect to each other utilizing the process of dynamic calibration by comparison. Usually the Pearson's correlation analysis coefficient is applied for this purpose. However, in some cases the method does not bring satisfactory results, as it can be seen in the results of the research conducted for the purpose of this paper. The Dynamic Time Warping method may be the solution to this problem, as it appears to be more efficient while comparing the shapes of calibration characteristics done with the use of the Pearson's method...
November 30, 2018: Sensors
https://www.readbyqxmd.com/read/30513628/innovative-strain-sensing-for-detection-of-exterior-wall-tile-lesion-smart-skin-sensory-system
#19
Chih-Yuan Chang, San-Shan Hung, Li-Hua Liu, Chien-Pang Lin
Tiles are commonly used to cover the exteriors of buildings in Taiwan. However, older buildings in Taiwan encounter the problem of tiles falling off due to natural deterioration, which is unsightly, and more importantly, a threat to public safety. Nevertheless, no current method exists that can effectively detect flaws in building tiles in real time. This study combined the fields of civil engineering and automatic control to reduce risks caused by falling tiles by improving real-time detection of at-risk areas...
November 30, 2018: Materials
https://www.readbyqxmd.com/read/30511834/assembly-of-highly-aligned-carbon-nanotubes-using-an-electro-fluidic-assembly-process
#20
Zhimin Chai, Jungho Seo, Salman A Abbasi, Ahmed Busnaina
Carbon nanotubes (CNTs) are promising building blocks for emerging wearable electronics and sensors due to their outstanding electrical and mechanical properties. However, the practical applications of the CNTs face challenges of efficiently and precisely placing them at the desired location with controlled orientation and density. Here, we introduce an electro-fluidic assembly process to assemble highly aligned and densely packed CNTs selectively on a substrate with patterned wetted areas at a high rate. An electric field is applied during the electro-fluidic assembly process, which drives the CNTs close to the patterned regions and shortens the assembly time...
December 4, 2018: ACS Nano
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