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https://www.readbyqxmd.com/read/18156711/gene-frequencies-of-human-neutrophil-antigens-4a-and-5a-in-the-korean-population
#1
Tae Hee Han, Kyou Sup Han
BACKGROUND: In Korean population, antigen frequencies of HNA-1a, HNA-1b, and HNA-2a are determined using a serological and genotyping method. However, no study has been done to assess the gene frequencies of HNA-4a and HNA-5a. It has been reported that the antibody against HNA-4a is associated with alloimmune neutropenia and autoimune neutropenia; however, there is no confirmed clinical report on anti-HNA-5a-related disorders. The aim of this study was to determine HNA-4a and HNA-5a gene frequencies among the Korean population...
April 2006: Korean Journal of Laboratory Medicine
https://www.readbyqxmd.com/read/16673863/-gene-similarity-between-hepatitis-c-virus-and-human-proteins-a-blood-transfusion-problem
#2
Nada Vasiljević, Ljiljana Marković
INTRODUCTION: Hepatitis C is a post-transfusion hepatitis which causes serious problems in blood transfusion. Blood testing requires highly sensitive and specific assays with high predictive value. GENOMIC CHARACTERISTICS OF HEPATITIS C VIRUS: According to recommendations of International Association for the study of Liver Diseases etiological diagnosis of hepatitis is based on highly sensitive third generation assays: epitopes in the NS5 region comprising noncoding sequence UTR with 324-341 well conserved pair of homologous basis in 92% HCV genomes, therefore appropriate for virus RNA detection...
November 2005: Medicinski Pregled
https://www.readbyqxmd.com/read/10900360/-allograft-inflammatory-factor-1-is-upregulated-in-microglial-cells-in-human-cerebral-infarctions
#3
E Postler, A Rimner, R Beschorner, H J Schluesener, R Meyermann
Allograft inflammatory factor-1 (AIF-1) is a 17-kDa-peptide identified in rat cardiac allografts undergoing chronic rejection and in activated microglial cells in inflammatory autoimune disease of the CNS. We have investigated the expression of AIF-1 in 18 autopsy cases of human focal cerebral infarction. AIF-1-positive cells show the morphology of microglia and are CD68- but not GFAP-positive. The peptide is expressed at a low level in normal brain. In infarctions, activated microglial cells in the area of glial reaction show strongly enhanced cytoplasmic immunoreactivity...
August 1, 2000: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/10683518/allograft-inflammatory-factor-1-is-upregulated-in-microglial-cells-in-human-cerebral-infarctions
#4
E Postler, A Rimner, R Beschorner, H J Schluesener, R Meyermann
Allograft inflammatory factor-1 (AIF-1) is a 17-kDa-peptide identified in rat cardiac allografts undergoing chronic rejection and in activated microglial cells in inflammatory autoimune disease of the CNS. We have investigated the expression of AIF-1 in 18 autopsy cases of human focal cerebral infarction. AIF-1-positive cells show the morphology of microglia and are CD68- but not GFAP-positive. The peptide is expressed at a low level in normal brain. In infarctions, activated microglial cells in the area of glial reaction show strongly enhanced cytoplasmic immunoreactivity...
April 3, 2000: Journal of Neuroimmunology
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