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Caroline Dana, Zagorka Péjin, Céline Cadilhac, Philippe Wicart, Christophe Glorion, Jean-Charles Aurégan
The "horseman" procedure is a surgical technique used to correct the talocalcaneal joint displacement of severe idiopathic flatfoot in children while maintaining the reduction with a temporary talocalcaneal screw. While this technique has been used since the early 1960s, very little has been reported on its results. Our objectives were to estimate the correction, functional results, and postoperative complications of the "horseman" procedure. We conducted a retrospective study on 23 consecutive patients (41 cases) who underwent the "horseman" procedure for a talocalcaneal joint displacement...
October 16, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
Kylie Davis, John L Williams, Brooke A Sanford, Audrey Zucker-Levin
BACKGROUND: Despite our knowledge of several biomechanical risk factors related to anterior cruciate ligament (ACL) injury, such as decreased knee flexion, increased knee abduction, and increased hip flexion, adduction and internal rotation during walking, jogging, and landing from a jump, the incidence of ACL tears remains high. Quantifying variability in the lower extremity provides a continuous measure of joint coordination and function that may elicit an additional aspect of ACL injury mechanisms...
October 10, 2018: Gait & Posture
Kyung-Min Kim, Joo-Sung Kim, Jeonghoon Oh, Sae Yong Lee
BACKGROUND: Acute lateral ankle sprain (ALAS) impairs unipedal balance both with the injured and uninjured limb, suggesting that balance during bipedal stance may also be compromised. However, a previous study failed to find such impairment because of poorly sensitive balance outcomes. Time-to-boundary (TTB) analysis may be sensitive enough for detecting latent deficits in bipedal balance following ALAS. RESEARCH QUESTION: We aimed to examine postural stability during bipedal stance in patients with ALAS using TTB outcomes, and to determine bilateral deficits in unipedal balance...
October 9, 2018: Gait & Posture
Willythssa S Pierre-Louis, Jonathan Bath, Sesank Mikkilineni, Michael C Scott, Michael Harlander-Locke, Zachary Rasor, Matthew Smeds
OBJECTIVE: The neutrophil to lymphocyte ratio (NLR) has become a prognostic marker for pro-inflammatory states. It is associated with outcomes in many clinical processes including critical limb ischemia. We sought to identify predictors of amputation failure and mortality, in addition to the role of NLR in patients undergoing above knee amputations (AKA) or below knee amputations (BKA). METHODS: All patients undergoing BKA or AKA between 2004 and 2014 at three institutions were identified and analyzed (n=513)...
October 16, 2018: Annals of Vascular Surgery
Lumei Huang, Zijing Li, Deliang Zhang, Hua Li, Changrong Shi, Pu Zhang, Xinhui Su, Xianzhong Zhang
Superoxide (O2 •- ) is a specific molecular target for xenobiotics, cytokines, and bacteria during inflammatory diseases. The aim of this study is to develop a single-photon emission computed tomography (SPECT) imaging agent and to quantify the distribution of O2 •- in vivo. 125/131 I-PISO was obtained in good radiochemical yield (65.4 ± 9.2%) and high radiochemical purity (>98%) after HPLC purification. 125/131 I-PISO (log P = 2.46) could be oxidized by O2 •- selectively and sensitively, converted to a hydrophilic compound 125/131 I-PISA (log P = -1...
October 19, 2018: Analytical Chemistry
Lía Nattero-Chávez, Sandra Redondo López, Sara Alonso Díaz, Marta Garnica Ureña, Elena Fernández-Durán, Héctor F Escobar-Morreale, Manuel Luque-Ramírez
AIMS: Epidemiological data on subclinical atherosclerotic disease in type 1 diabetes mellitus (DM1) are scarce. We aimed to estimate the subclinical atherosclerosis profile of asymptomatic patients with DM1 and an abnormal ankle-brachial index (ABI). MATERIAL AND METHODS: In a cross-sectional design ( Identifier: NCT02910271), we estimated ABI in 289 consecutive asymptomatic patients with DM1. An abnormal ABI led to measurements of toe-brachial index (TBI) and peripheral doppler ultrasound (DUS) to diagnose peripheral artery disease (PAD) and/or atherosclerotic carotid plaques (ACP)...
October 19, 2018: Diabetes/metabolism Research and Reviews
Pejma Shazadeh Safavi, Cory Janney, Daniel Jupiter, Daniel Kunzler, Roger Bui, Vinod K Panchbhavi
BACKGROUND: The goal of this systematic review is to determine the most commonly used outcome measurement tools used by foot and ankle specialists and determine their limitations, such as whether they are validated, have floor/ceiling effects, and so on. METHODS: A literature search was conducted to identify primary publications between January 1, 2012 and July 1, 2017 that concern care of the foot and ankle and use any established grading criteria to evaluate patients...
October 19, 2018: Foot & Ankle Specialist
Jun Inamo, Yuko Kaneko, Komei Sakata, Tsutomu Takeuchi
OBJECTIVE: To investigate the impact of subclinical synovitis detected by ultrasonography (US) on the ankles and feet of patients with rheumatoid arthritis. METHODS: We retrospectively reviewed the data of patients (n = 59) who underwent US. RESULTS: The functional ability and quality of life (QoL) of patients in the subclinical group were impaired. While the physician visual analog scale (VAS) scores significantly decreased in the subclinical group, patient and pain VAS scores significantly decreased only in patients without synovitis...
October 18, 2018: International Journal of Rheumatic Diseases
Paweł Kaczmarczyk, Marek Krzanowski, Ewelina Szybiak, Mikołaj Maga, Agnieszka Wachsmann, Katarzyna Tyrak, Rafał Januszek, Andrzej Belowski, Łukasz Partyka, Paweł Maga
BACKGROUND: Patients with advanced lower limb ischemia are at present, mainly treated using revascularization. AIM: The aim of the study was to investigate whether the dynamics of blood flow in below-the-knee (BTK) arteries assessed at angiogram completion correlate with clinical outcomes after a 12-month follow-up period among patients with severe leg ischemia treated percutaneously. METHODS: The current study enrolled 287 consecutive patients who underwent 302 endovascular procedures on the infra-inguinal arteries...
October 19, 2018: Kardiologia Polska
Lynn Bar-On, Barbara M Kalkman, Francesco Cenni, Simon-Henri Schless, Guy Molenaers, Constantinos N Maganaris, Alfie Bass, Gill Holmes, Gabor J Barton, Thomas D O'Brien, Kaat Desloovere
Stretch reflex hyperactivity in the gastrocnemius of children with spastic cerebral palsy (CP) is commonly evaluated by passively rotating the ankle joint into dorsiflexion at different velocities, such as applied in conventional clinical spasticity assessments. However, surface electromyography (sEMG) collected from the medial gastrocnemius (MG) during such examination reveals unexplained heterogeneity in muscle activation between patients. Recent literature also highlights altered muscle tensile behavior in children with spastic CP...
2018: Frontiers in Pediatrics
Carl Pellerin, Vinod Panchbhavi, Cory F Janney
Introduction Orthopaedic devices represent 12% of all medical device recalls. Products are approved through pre-market approval (PMA) or the 510(k) premarket notification process. No previous evaluation was found in the literature evaluating foot and ankle device recalls. The field of foot and ankle subspecialty has seen a rapid growth in innovation related to implants in recent years. Methods The Food and Drug Administration (FDA) Device Recall database was evaluated for all foot and ankle devices from 2007 through 2017 for the manufacturer, process of approval, type of implant, recall class, dates of initiation and termination of the recall, manufacturer determined reason, quantity affected, and distribution within the United States or internationally...
August 9, 2018: Curēus
Tun Hing Lui
Os calcaneus secundarius is an accessory ossicle resulting from a secondary ossification center of the anterior facet of the calcaneus. It may cause chronic pain and limitation in inversion motion after inversion ankle sprain. Excision of the ossicle is indicated if the symptoms do not resolve with conservative treatment. A case of symptomatic os calcaneus secundarius, which was successfully resected endoscopically, is presented.
April 30, 2018: Foot
Esat Uygur, Murat Demiroğlu, Davut Aydin, Bülent Kiliç, Korhan Özkan
INTRODUCTION: Trevor's disease, also known as dyplasia epiphysealis hemimelica, is characterised by osteochondromas arising from epiphyses. The disease typically affects one side of an epiphysis (usually the medial side). CASE PRESENTATION: A case in whom both the medial and lateral sides of the epiphysis were involved is described. Thus, the use of the descriptor "hemimelica" is not always appropriate. CONCLUSION: Although rare, Trevor's disease should be kept in mind during the differential diagnosis of patients with ankle pain and a mass...
January 31, 2018: Foot
Varsha S Honmore, Amit Kandhare, Parag P Kadam, Vijay M Khedkar, Arun D Natu, Supada R Rojatkar, Subhash L Bodhankar
ETHNOPHARMACOLOGICAL RELEVANCE: Rheumatoid arthritis (RA) is a chronic inflammatory and destructive joint disease that affects the worldwide population. Alpinia officinarum Hance (Zingiberaceae), rhizomes are widely used ethnobotanically as an anti-inflammatory, analgesic, and antioxidant agent in traditional medicine. AIM: To investigate the efficacy and possible mechanism of isolated phytoconstituent from the methanol extract of A. officinarum (MEAO) rhizomes against Freund's complete adjuvant (FCA)-induced arthritis in rats...
October 15, 2018: Journal of Ethnopharmacology
Claire E J Waterborg, Marije I Koenders, Peter L E M van Lent, Peter M van der Kraan, Fons A J van de Loo
Rheumatoid arthritis is an auto-immune disease of the synovial joints, hallmarked by chronic inflammation and subsequent progressive tissue destruction. TYRO3, AXL and MER (gene name Mertk) (TAM) receptors are part of a negative feedback signaling system in the immune reaction and mediate efferocytosis thereby tempering the inflammatory process. We have shown that Axl-/- and Mertk-/- mice develop more severe arthritis whereas activating these receptors by overexpressing their ligands Pros1 and Gas6 ameliorates arthritis...
2018: PloS One
Yu Wang, Xuerong Deng, Yufeng Xu, Lanlan Ji, Zhuoli Zhang
The aim of our study was to compare the performance of ultrasonography (US) and dual-energy computed tomography (DECT) in detecting the crystal deposition at lower extremity joints in patients with gout. The correlation of imaging findings with microscopic findings was further assessed whenever aspiration is available.We recruited consecutive patients who were presented with arthritis of lower extremity from January 2012 to December 2014. All the patients underwent DECT and US scan of bilateral knees, ankles, and feet...
October 2018: Medicine (Baltimore)
Benjamin K Potter, Robert G Sheu, Daniel Stinner, John Fergason, Joseph R Hsu, Kevin Kuhn, Johnny G Owens, Jessica Rivera, Scott B Shawen, Jason M Wilken, Jennifer DeSanto, Yanjie Huang, Daniel O Scharfstein, Ellen J MacKenzie
BACKGROUND: The Intrepid Dynamic Exoskeletal Orthosis (IDEO) is a custom energy-storing carbon fiber ankle-foot orthosis developed for lower-extremity trauma patients. Studies conducted at the military treatment facility where the IDEO was developed demonstrated benefits of the IDEO when used with the Return to Run Physical Therapy (RTR PT) program. The current study was designed to determine if results could be replicated at other military treatment facilities and to examine whether early performance gains in patient-reported functional outcomes remained at 12 months...
October 17, 2018: Journal of Bone and Joint Surgery. American Volume
P F Stillhard, H Frima, C Sommer
The majority of pilon or tibial plafond fractures are complex articular fractures and the treatment strategy, including the choice of the ideal surgical approach, is essential for a good functional outcome. In this paper, we discuss the considerations for dealing with such fractures as well as the pro and cons of the different approaches. The standard protocol consists of a two-staged procedure following the slogan span-scan-plan. After applying an ankle-spanning external fixator (span), the diagnostic work-up is completed by a CT scan with axial views, two-dimensional and three-dimensional reconstruction (scan) to fully understand the fracture pattern...
October 17, 2018: Operative Orthopädie und Traumatologie
Kimberly A Ingraham, Hwan Choi, Emily S Gardinier, C David Remy, Deanna H Gates
Powered ankle prostheses have been designed to reduce the energetic burden that individuals with transtibial amputation experience during ambulation. There is an open question regarding how much power the prosthesis should provide, and whether approximating biological ankle kinetics is optimal to reduce the metabolic cost of users. We tested 10 individuals with transtibial amputation walking on a treadmill wearing the BiOM powered ankle prosthesis programmed with 6 different power settings (0-100%), including a prosthetist-chosen setting, chosen to approximate biological ankle kinetics...
October 17, 2018: Scientific Reports
Banibrata Das
Aims: The purpose of this study was to describe the health hazards among child labourers in brickfields, and to assess occupational health problems, together with physiological and respiratory stress, compared with child control subjects. Methods: A cross-sectional study was conducted on 112 child brickfield workers and 120 control subjects, and a modified Nordic Questionnaire was applied to assess the discomfort felt among both groups of workers. Physiological assessment of the workload was carried out by the measurement of heart rate, blood pressure and spirometry of the workers...
October 17, 2018: International Health
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