keyword
https://read.qxmd.com/read/37622409/abnormal-white-matter-structural-network-topological-property-in-patients-with-temporal-lobe-epilepsy
#1
JOURNAL ARTICLE
Haiming Ai, Chunlan Yang, Min Lu, Jiechuan Ren, Zhimei Li, Yining Zhang
BACKGROUND: Diffusion tensor imaging (DTI) studies have demonstrated white matter (WM) abnormalities in patients with temporal lobe epilepsy (TLE). However, alterations in the topological properties of the WM structural network in patients with TLE remain unclear. Graph theoretical analysis provides a new perspective for evaluating the connectivity of WM structural networks. METHODS: DTI was used to map the structural networks of 18 patients with TLE (10 males and 8 females) and 29 (17 males and 12 females) age- and gender-matched normal controls (NC)...
August 25, 2023: CNS Neuroscience & Therapeutics
https://read.qxmd.com/read/37301366/the-asymmetry-of-glymphatic-system-dysfunction-in-patients-with-temporal-lobe-epilepsy-a-dti-alps-study
#2
JOURNAL ARTICLE
Xu Zhao, Yingying Zhou, Yuanhao Li, Shanshan Huang, Hongquan Zhu, Zhiqiang Zhou, Suiqiang Zhu, Wenzhen Zhu
BACKGROUND AND PURPOSE: While the occurrence of glymphatic system dysfunction has been observed in temporal lobe epilepsy (TLE), the potential asymmetry of this system has yet to be investigated in the TLE context. We aimed to investigate the glymphatic system function in both hemispheres and to analyze asymmetric features of the glymphatic system in TLE patients using diffusion tensor image analysis along the perivascular space (DTI-ALPS) method. MATERIALS AND METHODS: 43 patients (left TLE (LTLE), n = 20; right TLE (RTLE), n = 23) and 39 healthy controls (HC) were enrolled in this study...
June 8, 2023: Journal of Neuroradiology. Journal de Neuroradiologie
https://read.qxmd.com/read/37088608/visual-networks-electric-brain-stimulation-and-diffusion-tensor-imaging
#3
JOURNAL ARTICLE
Tomoaki Tamada, Rei Enatsu, Takuro Saito, Ryohei Chiba, Aya Kanno, Nobuhiro Mikuni
OBJECTIVE: The present study investigated the networks of visual functional areas using electric brain stimulation (EBS) and diffusion tensor imaging (DTI). METHODS: Thirteen patients with intractable focal epilepsy in which visual functional areas were identified by EBS were enrolled. An electric stimulation at 50Hz was applied to electrodes during several tasks. DTI was used to identify subcortical fibers originating from the visual functional areas identified by EBS...
April 21, 2023: Revue Neurologique
https://read.qxmd.com/read/37033907/brain-diffusion-tensor-imaging-reveals-altered-connections-and-networks-in-epilepsy-patients
#4
JOURNAL ARTICLE
Meixia Wang, Xiaoyu Cheng, Qianru Shi, Bo Xu, Xiaoxia Hou, Huimin Zhao, Qian Gui, Guanhui Wu, Xiaofeng Dong, Qinrong Xu, Mingqiang Shen, Qingzhang Cheng, Shouru Xue, Hongxuan Feng, Zhiliang Ding
INTRODUCTION: Accumulating evidence shows that epilepsy is a disease caused by brain network dysfunction. This study explored changes in brain network structure in epilepsy patients based on graph analysis of diffusion tensor imaging data. METHODS: The brain structure networks of 42 healthy control individuals and 26 epilepsy patients were constructed. Using graph theory analysis, global and local network topology parameters of the brain structure network were calculated, and changes in global and local characteristics of the brain network in epilepsy patients were quantitatively analyzed...
2023: Frontiers in Human Neuroscience
https://read.qxmd.com/read/37010581/recovery-of-glymphatic-system-function-in-patients-with-temporal-lobe-epilepsy-after-surgery
#5
JOURNAL ARTICLE
Chao Zhang, Kai Xu, Haiyan Zhang, Jingyun Sha, Hongyu Yang, Houliang Zhao, Nan Chen, Kuncheng Li
OBJECTIVES: To investigate the recovery of human glymphatic system (GS) function in patients with temporal lobe epilepsy (TLE) after successful anterior temporal lobectomy (ATL) using diffusion tensor image analysis along the perivascular space (DTI-ALPS). METHODS: We retrospectively analysed DTI-ALPS index in 13 patients with unilateral TLE before and after ATL, and compared the index with 20 healthy controls (HCs). Two-sample t tests and paired t tests were performed to analyse differences in the DTI-ALPS index between patients and HCs...
September 2023: European Radiology
https://read.qxmd.com/read/36529714/visual-outcomes-after-anterior-temporal-lobectomy-and-transsylvian-selective-amygdalohippocampectomy-a-quantitative-comparison-of-clinical-and-diffusion-data
#6
JOURNAL ARTICLE
Philip Pruckner, Karl-Heinz Nenning, Florian Ph S Fischmeister, Mehmet-Salih Yildirim, Michelle Schwarz, Andreas Reitner, Susanne Aull-Watschinger, Johannes Koren, Christoph Baumgartner, Daniela Prayer, Karl Rössler, Christian Dorfer, Thomas Czech, Ekaterina Pataraia, Gregor Kasprian, Silvia Bonelli
OBJECTIVE: Anterior temporal lobectomy (ATL) and transsylvian selective amygdalohippocampectomy (tsSAHE) are effective treatment strategies for intractable temporal lobe epilepsy but may cause visual field deficits (VFDs) by damaging the optic radiation (OpR). Due to the OpR's considerable variability and because it is indistinguishable from surrounding tissue without further technical guidance, it is highly vulnerable to iatrogenic injury. This imaging study uses a multimodal approach to assess visual outcomes after epilepsy surgery...
December 18, 2022: Epilepsia
https://read.qxmd.com/read/36461649/longitudinal-hippocampal-diffusion-weighted-imaging-and-t2-relaxometry-demonstrate-regional-abnormalities-which-are-stable-and-predict-subfield-pathology-in%C3%A2-temporal%C3%A2-lobe%C3%A2-epilepsy
#7
JOURNAL ARTICLE
Seyed Amir Ali Adel, Sarah Treit, Wasan Abd Wahab, Graham Little, Laura Schmitt, Alan H Wilman, Christian Beaulieu, Donald W Gross
OBJECTIVE: High-resolution (1 mm isotropic) diffusion tensor imaging (DTI) of the hippocampus in temporal lobe epilepsy (TLE) patients has shown patterns of hippocampal subfield diffusion abnormalities, which were consistent with hippocampal sclerosis (HS) subtype on surgical histology. The objectives of this longitudinal imaging study were to determine the stability of focal hippocampus diffusion changes over time in TLE patients, compare diffusion and quantitative T2 abnormalities of the sclerotic hippocampus, and correlate presurgical mean diffusivity (MD) and T2 maps with postsurgical histology...
December 2, 2022: Epilepsia Open
https://read.qxmd.com/read/36141260/changes-in-the-brain-in-temporal-lobe-epilepsy-with-unilateral-hippocampal-sclerosis-an-initial-case-series
#8
JOURNAL ARTICLE
Sung Chul Lim, Juhee Oh, Bo Young Hong, Seong Hoon Lim
Temporal lobe epilepsy (TLE) is a network disorder of the brain. Network disorders predominately involve dysregulation of hippocampal function caused by neuronal hyperexcitability. However, the relationship between the macro- and microscopic changes in specific brain regions is uncertain. In this study, the pattern of brain atrophy in patients with TLE and hippocampal sclerosis (HS) was investigated using volumetry, and microscopic changes in specific lesions were observed to examine the anatomical correspondence with specific target lesions using diffusion tensor imaging (DTI) with statistical parametric mapping (SPM)...
August 29, 2022: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/36138904/characteristics-of-microstructural-changes-associated-with-glioma-related-epilepsy-a-diffusion-tensor-imaging-dti-study
#9
JOURNAL ARTICLE
Hong Zhang, Chunyao Zhou, Qiang Zhu, Tianshi Li, Yinyan Wang, Lei Wang
(1) Background: Glioma is the most common primary tumor in the central nervous system, and glioma-related epilepsy (GRE) is one of its common symptoms. The abnormalities of white matter fiber tracts are involved in attributing changes in patients with epilepsy (Rudà, R, 2012).This study aimed to assess frontal lobe gliomas' effects on the cerebral white matter fiber tracts. (2) Methods: Thirty patients with frontal lobe glioma were enrolled and divided into two groups (Ep and nEep). Among them, five patients were excluded due to apparent insular or temporal involvement...
August 31, 2022: Brain Sciences
https://read.qxmd.com/read/35707885/superficial-and-deep-white-matter-diffusion-abnormalities-in-focal-epilepsies
#10
JOURNAL ARTICLE
Hebel Urquia-Osorio, Luciana R Pimentel-Silva, Thiago Junqueira Ribeiro Rezende, Eimy Almendares-Bonilla, Clarissa L Yasuda, Luis Concha, Fernando Cendes
OBJECTIVE: This study was undertaken to evaluate superficial-white matter (WM) and deep-WM magnetic resonance imaging diffusion tensor imaging (DTI) metrics and identify distinctive patterns of microstructural abnormalities in focal epilepsies of diverse etiology, localization, and response to antiseizure medication (ASM). METHODS: We examined DTI data for 113 healthy controls and 113 patients with focal epilepsies: 51 patients with temporal lobe epilepsy (TLE) and hippocampal sclerosis (HS) refractory to ASM, 27 with pharmacoresponsive TLE-HS, 15 with temporal lobe focal cortical dysplasia (FCD), and 20 with frontal lobe FCD...
September 2022: Epilepsia
https://read.qxmd.com/read/34961746/diagnostic-value-of-mri-in-the-presurgical-evaluation-of-patients-with-epilepsy-influence-of-field-strength-and-sequence-selection-a-systematic-review-and-meta-analysis-from-the-e-pilepsy-consortium
#11
JOURNAL ARTICLE
Matea Rados, Brian Mouthaan, Peter Barsi, David Carmichael, Rolf A Heckemann, Anna Kelemen, Teia Kobulashvili, Giorgi Kuchukhidze, Petr Marusic, Krasimir Minkin, Martin Tisdall, Eugen Trinka, Tim Veersema, Sjoerd B Vos, Jan Wagner, Kees Braun, Pieter van Eijsden
MRI is a cornerstone in presurgical evaluation of epilepsy. Despite guidelines, clinical practice varies. In light of the E-PILEPSY pilot reference network, we conducted a systematic review and meta-analysis on the diagnostic value of MRI in the presurgical evaluation of epilepsy patients. We included original research articles on diagnostic value of higher MRI field strength and guideline-recommended and additional MRI sequences in detecting an epileptogenic lesion in adult or paediatric epilepsy surgery candidates...
April 1, 2022: Epileptic Disorders: International Epilepsy Journal with Videotape
https://read.qxmd.com/read/34838665/infantile-status-epilepticus-disrupts-myelin-development
#12
JOURNAL ARTICLE
Petra Bencurova, Hanne Laakso, Raimo A Salo, Ekaterina Paasonen, Eppu Manninen, Jaakko Paasonen, Shalom Michaeli, Silvia Mangia, Martin Bares, Milan Brazdil, Hana Kubova, Olli Gröhn
Temporal lobe epilepsy (TLE) is the most prevalent type of epilepsy in adults; it often starts in infancy or early childhood. Although TLE is primarily considered to be a grey matter pathology, a growing body of evidence links this disease with white matter abnormalities. In this study, we explore the impact of TLE onset and progression in the immature brain on white matter integrity and development utilising the rat model of Li-pilocarpine-induced TLE at the 12th postnatal day (P). Diffusion tensor imaging (DTI) and Black-Gold II histology uncovered disruptions in major white matter tracks (corpus callosum, internal and external capsules, and deep cerebral white matter) spreading through the whole brain at P28...
January 2022: Neurobiology of Disease
https://read.qxmd.com/read/34817885/effects-of-laser-interstitial-thermal-therapy-for-mesial-temporal-lobe-epilepsy-on-the-structural-connectome-and-its-relationship-to-seizure-freedom
#13
JOURNAL ARTICLE
Andrew L Ko, Ai Phuong S Tong, Mahmud Mossa-Basha, Kurt E Weaver, Jeffrey G Ojemann, John W Miller, Shahin Hakimian
OBJECTIVE: Laser interstitial thermal therapy (LITT) is a minimally invasive surgery for mesial temporal lobe epilepsy (mTLE), but the effects of individual patient anatomy and location of ablation volumes affect seizure outcomes. The purpose of this study is to see if features of individual patient structural connectomes predict surgical outcomes after LITT for mTLE. METHODS: This is a retrospective analysis of seizure outcomes of LITT for mTLE in 24 patients. We use preoperative diffusion tensor imaging (DTI) to simulate changes in structural connectivity after laser ablation...
November 24, 2021: Epilepsia
https://read.qxmd.com/read/34803885/prospective-quantitative-neuroimaging-analysis-of-putative-temporal-lobe-epilepsy
#14
JOURNAL ARTICLE
Kost Elisevich, Esmaeil Davoodi-Bojd, John G Heredia, Hamid Soltanian-Zadeh
Purpose: A prospective study of individual and combined quantitative imaging applications for lateralizing epileptogenicity was performed in a cohort of consecutive patients with a putative diagnosis of mesial temporal lobe epilepsy (mTLE). Methods: Quantitative metrics were applied to MRI and nuclear medicine imaging studies as part of a comprehensive presurgical investigation. The neuroimaging analytics were conducted remotely to remove bias. All quantitative lateralizing tools were trained using a separate dataset...
2021: Frontiers in Neurology
https://read.qxmd.com/read/34801803/cortical-regions-and-networks-of-hyperkinetic-seizures-electrocorticography-and-diffusion-tensor-imaging-study
#15
JOURNAL ARTICLE
Ayaka Sasagawa, Rei Enatsu, Tomoyoshi Kuribara, Masayasu Arihara, Tsukasa Hirano, Satoko Ochi, Nobuhiro Mikuni
OBJECTIVE: The present study investigated the cortical areas and networks responsible for hyperkinetic seizures by analyzing invasive recordings and diffusion tensor imaging (DTI) tractography. METHODS: Seven patients with intractable focal epilepsy in whom hyperkinetic seizures were recorded during an invasive evaluation at Sapporo Medical University between January 2012 and March 2020 were enrolled in the present study. Intracranial recordings were analyzed to localize seizure-onset zones (SOZs) and symptomatogenic zones (spread areas at clinical onset)...
December 2021: Epilepsy & Behavior: E&B
https://read.qxmd.com/read/34642939/decoupling-of-functional-and-structural-language-networks-in-temporal-lobe-epilepsy
#16
JOURNAL ARTICLE
Karin Trimmel, Sjoerd B Vos, Lorenzo Caciagli, Fenglai Xiao, Louis A van Graan, Gavin P Winston, Matthias J Koepp, Pamela J Thompson, John S Duncan
OBJECTIVE: To identify functional and structural alterations in language networks of people with temporal lobe epilepsy (TLE), who frequently present with naming and word-finding difficulties. METHODS: Fifty-five patients with unilateral TLE (29 left) and 16 controls were studied with auditory and picture naming functional magnetic resonance imaging (fMRI) tasks. Activation maxima in the left posterobasal temporal lobe were used as seed regions for whole-brain functional connectivity analyses (psychophysiological interaction)...
December 2021: Epilepsia
https://read.qxmd.com/read/34515307/gray-white-matter-blurring-of-the-temporal-pole-associated-with-hippocampal-sclerosis-a-microstructural-study-involving-3-t-mri-and-ultrastructural-histopathology
#17
JOURNAL ARTICLE
T Demerath, C Donkels, M Reisert, M Heers, A Rau, N Schröter, A Schulze-Bonhage, P Reinacher, C Scheiwe, M J Shah, J Beck, A Vlachos, C A Haas, H Urbach
Hippocampal sclerosis (HS) is often associated with gray-white matter blurring (GMB) of the anterior temporal lobe. In this study, twenty patients with unilateral temporal lobe epilepsy and HS were studied with 3 T MRI including T1 MP2RAGE and DTI/DMI sequences. Anterior temporal lobe white matter T1 relaxation times and diffusion measures were analyzed on the HS side, on the contralateral side, and in 10 normal controls. Resected brain tissue of three patients without GMB and four patients with GMB was evaluated ultrastructurally regarding axon density and diameter, the relation of the axon diameter to the total fiber diameter (G-ratio), and the thickness of the myelin sheath...
September 13, 2021: Cerebral Cortex
https://read.qxmd.com/read/34401999/unilateral-blinking-insights-from-stereo-eeg-and-tractography
#18
JOURNAL ARTICLE
Elisabeth Kaufmann, Joanna Bartkiewicz, Nicholas Fearns, Katharina Ernst, Christian Vollmar, Soheyl Noachtar
To study the neuroanatomical correlate of involuntary unilateral blinking in humans, using the example of patients with focal epilepsy. Patients with drug resistant focal epilepsy undergoing presurgical evaluation with stereotactically implanted EEG-electrodes (sEEG) were recruited from the local epilepsy monitoring unit. Only patients showing ictal unilateral blinking or unilateral blinking elicited by direct electrical stimulation were included (n = 16). MRI and CT data were used for visualization of the electrode positions...
September 2021: Brain Topography
https://read.qxmd.com/read/34347200/comparison-of-multimodal-findings-on-epileptogenic-side-in-temporal-lobe-epilepsy-using-self-organizing-maps
#19
JOURNAL ARTICLE
Alireza Fallahi, Mohammad Pooyan, Jafar Mehvari Habibabadi, Mohammad-Reza Nazem-Zadeh
OBJECTIVE: To develop a decision-making tool to evaluate and compare the performance of neuroimaging markers with clinical findings and the significance of attributes for presurgical lateralization of mesial temporal lobe epilepsy (mTLE). METHODS: Thirty-five unilateral mTLE patients who qualified as candidates for surgical resection were studied. Seizure semiology, ictal EEG, ictal epileptogenic zone, interictal-irritative zone, and MRI findings were used as clinical markers...
April 2022: Magma
https://read.qxmd.com/read/34155915/white-matter-integrity-in-a-rat-model-of-epileptogenesis-structural-connectomics-and-fixel-based-analysis
#20
JOURNAL ARTICLE
Emma Christiaen, Marie-Gabrielle Goossens, Benedicte Descamps, Jean Delbeke, Wytse Wadman, Kristl Vonck, Paul Boon, Robrecht Raedt, Christian Vanhove
Introduction: Electrophysiological and neuroimaging studies have demonstrated that large-scale brain networks are affected during the development of epilepsy. These networks can be investigated by using diffusion magnetic resonance imaging (dMRI). The most commonly used model to analyze dMRI is diffusion tensor imaging (DTI). However, DTI metrics are not specific to microstructure or pathology and the DTI model does not take into account crossing fibers, which may lead to erroneous results. To overcome these limitations, a more advanced model based on multi-shell multi-tissue constrained spherical deconvolution was used in this study to perform tractography with more precise fiber orientation estimates and to assess changes in intra-axonal volume by using fixel-based analysis...
May 2022: Brain Connectivity
keyword
keyword
159427
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.