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diabetic AND foot

Karen M Van de Velde-Kossmann
Renal failure patients have an increased risk of infection, including skin and soft tissue infections. This increased susceptibility is multifactorial, due to the conditions causing the renal failure as well as complications of treatment and renal failure's innate effects on patient health. These infections have a significant impact on patient morbidity, increased hospital and procedural demands, and the cost of health care. Many renal failure patients are seen regularly by their nephrology clinic caregivers due to the need for frequent dialysis and transplant monitoring...
December 5, 2018: Blood Purification
Felipe Tavares Rodrigues, Valéria Magalhães Aguiar, Claudia Soares Lessa
No abstract text is available yet for this article.
November 2018: Revista da Sociedade Brasileira de Medicina Tropical
Suzana Fiore Scain, Elenara Franzen, Vânia Naomi Hirakata
OBJECTIVES: Identify in patients with type 2 diabetes what changes in the feet would be associated with demographic, clinical, biochemical and treatment characteristics and which would increase the risk of mortality. METHODS: Retrospective longitudinal study evaluating the alterations in feet of outpatients attended at a nursing visit. Data from the clinical history and foot exam were collected from 918 medical records of a convenience sample. RESULTS: At 10 years, the cumulative mortality attributable to peripheral polyneuropathy was 44...
November 29, 2018: Revista Gaúcha de Enfermagem
Maria do Livramento Saraiva Lucoveis, Mônica Antar Gamba, Maria Angela Boccara de Paula, Ana Beatriz Pinto da Silva Morita
OBJECTIVE: To classify the level of risk for foot ulcers in people with diabetes mellitus and identify their main predictive risk factors. METHOD: Exploratory, descriptive study, in which patients were assessed in a municipal ambulatory of São Paulo through nursing consultation, following the guidelines of the International Consensus on the Diabetic Foot. Data were descriptively analyzed. RESULTS: The analyzed population was composed of 50 longevous and retired people, with household income of up to two minimum wages, with dermato-neurofunctional risk factors and unfavorable clinical indicators, and 66% had Risk 1; 16% Risk 2; 6% Risk 3 and 12% Risk 4...
November 2018: Revista Brasileira de Enfermagem
M A B Melo, W Caetano, E L Oliveira, P M Barbosa, A L B Rando, M M D Pedrosa, V A F Godoi
Photodynamic therapy, by reducing pain and inflammation and promoting the proliferation of healthy cells, can be used to treat recurrent lesions, such as diabetic foot ulcers. Studies using the photosensitizer phthalocyanine, together with the nanostructured copolymeric matrix of Pluronic® and Carbopol® for the treatment of diabetic foot ulcers and leishmaniosis lesions, are showing promising outcomes. Despite their topical or subcutaneous administration, these molecules are absorbed and their systemic effects are unknown...
December 3, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
Sarah Alexandra Lynar, Claire Helen Robinson, Craig Steven Boutlis, Robert James Commons
BACKGROUND: An increasing prevalence of diabetes mellitus has led to a high risk of diabetic foot infections (DFI) and associated morbidity. However, little is known about the relationship between DFI and mortality. AIMS: To investigate the risk of mortality and associated factors in patients with DFI in an Australian context. METHODS: A prospective cohort study of inpatients with DFI between May 2012 and October 2016, at Royal Darwin Hospital, a tertiary referral hospital for the Top End of the Northern Territory...
December 4, 2018: Internal Medicine Journal
Jodi Binning, Jim Woodburn, Sicco Bus, Ruth Barn
Diabetic foot ulceration is a major complication associated with high morbidity. Little evidence exists on which interventions are effective at preventing ulceration. Participants who are adherent to self-care behaviours have significantly better outcomes. Motivational interviewing is an intervention that has been used successfully for conditions where adherence is important, such as reduction of obesity and HbA1c levels. A systematic review was conducted to determine whether motivational interviewing is effective at improving adherence for the prevention of Diabetic Foot Ulceration...
December 4, 2018: Diabetes/metabolism Research and Reviews
Laura Bolton
Diabetic foot ulcers (DFUs) remain a challenge for clinicians despite decades of study. Clinicians now realize that healing strategies should focus on the patient as well as the ulcer. The search continues for interventions that affected individuals and their care providers can count on to heal and manage these challenging wounds, stopping the dreaded progression to amputation and death. The path to healing a patient's DFU often requires multidisciplinary care, including consistent offloading of insensate areas, endocrinologic and metabolic control, and improved circulation...
December 2018: Wounds: a Compendium of Clinical Research and Practice
Julia Yuncken, Cylie M Williams, Renerus J Stolwyk, Terry P Haines
The original version of this article unfortunately contained an mistake in country name in all the affiliations. The county name was inadvertently published as USA, it should be Australia instead. The affiliations are corrected in this erratum.
November 30, 2018: Endocrine
Lara S Chapman, Anthony C Redmond, Karl B Landorf, Keith Rome, Anne-Maree Keenan, Robin Waxman, Begonya Alcacer-Pitarch, Heidi J Siddle, Michael R Backhouse
Background: Foot orthoses are frequently used but little is known about which types are used in contemporary practice. This study aimed to explore the types of foot orthoses currently used by podiatrists and the prescription variations in a range of conditions. Methods: A web-based, cross-sectional survey was distributed through professional bodies in the United Kingdom (UK), Australia, and New Zealand. Questions focussed on foot orthosis prescription habits in relation to 26 conditions affecting the back and lower limb...
2018: Journal of Foot and Ankle Research
Xiaoxiao Hu, Weishuai Lian, Xiaojun Zhang, Xue Yang, Jinxia Jiang, Maoquan Li
Background: Diabetes mellitus, one of the most prevalent chronic metabolic diseases, causes many complications. Among the complications, one of the most common chronic complications is diabetic foot ulcers (DFUs). Objective: This study was conducted to investigate the efficacy of negative pressure wound therapy using vacuum-assisted closure (VAC) combined with photon therapy for the management of DFUs. Patients and methods: The study included a total of 69 patients with DFUs during the period from January 2014 to December 2015...
2018: Therapeutics and Clinical Risk Management
L H Hitchman, J P Totty, A Raza, P Cai, G E Smith, D Carradice, T Wallace, A E Harwood, I C Chetter
OBJECTIVES: To assess the current available evidence examining the efficacy of extracorporeal shockwave therapy (ESWT) on healing of diabetic foot ulcers (DFU). DATA SOURCES: PubMed, Ovid MEDLINE, Web of Science, Embase, CINAHL Plus, Cochrane Central Registry of Controlled Trials and Clinical Trials Registry electronic databases were searched up to November 2017 for terms related to ESWT in DFU. REVIEW METHODS: Articles were identified and data extracted by two independent reviewers onto Review Manager 5...
November 26, 2018: Annals of Vascular Surgery
Catherine Dunyach-Remy, Charlotte Carrere, Hélène Marchandin, Sophie Schuldiner, Anne-Marie Guedj, Nicolas Cellier, Axelle Cadière, Catherine Lechiche, Albert Sotto, Jean-Philippe Lavigne
AIM: We evaluated the performance of Unyvero implant and tissue infections system (ITI) application (Curetis) to diagnose Diabetic Foot Osteomyelitis (DFOM). PATIENTS & METHODS: The study was conducted in the Diabetic Foot reference center of Nîmes University Hospital (France) from 1 December 2016 to 31 May 2017. We compared the Unyvero ITI PCR to conventional culture and alternative molecular approaches. RESULTS: A total of 79 patients with DFOM were included: 177 microorganisms were isolated by culture, 146 detected by PCR, resulting in a concordance level of 66...
November 29, 2018: Future Microbiology
Sanne M Schreuder, M Nieuwdorp, Marc J W Koelemay, Shandra Bipat, Jim A Reekers
Objective: There is evidence from the literature that dysfunctionality of the sympathetic nervous system of the foot with subsequent loss of local autoregulation could be a predictor of early amputation in patients with diabetes with a neuroischemic ulcer. To confirm this we tested the functionality of the sympathetic nervous system in the foot in a consecutive group of 31 patients with diabetes with critical limb ischemia and non-healing neuroischemic ulcer. Research design and methods: Prospective cohort with retrospective analysis after 12 months of routinely acquired clinical data...
2018: BMJ Open Diabetes Research & Care
Shane Hollawell, Brendan Kane, Christopher Heisey, Patricia Greenberg
Allogenic bone graft has long been accepted as a standard of care in the surgical arthrodesis of the foot and ankle and treatment of certain high-risk, comminuted fracture types that have greater potential for delayed union or nonunion. It has been shown in multiple studies to be equivalent to autograft in regard to union rates without the morbidity associated with bone graft harvest. We present a retrospective study on the efficacy of an allogenic cancellous/periosteal cellular bone matrix with mesenchymal stem cells and angiogenic growth factors...
November 28, 2018: Foot & Ankle Specialist
L H Chen, X X Ran
No abstract text is available yet for this article.
December 1, 2018: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
Faaiz Ul Hassan, Muhammad Suhaib Qudus, Sheikh Arslan Sehgal, Jawad Ahmed, Momin Khan, Khayam Ul Haq, Shahina Mumtaz, Muhammad Arshad, Sami Siraj
BACKGROUND: Pseudomonas aeruginosa is one of the major pathogen associated with acute tissue damage in patients with diabetic foot ulcer (DFU). Antibiotic resistance in P. aeruginosa often bodes unpredictable and unfavourable clinical outcomes, owing to a variety of intrinsic and acquired molecular mechanisms. The study aimed to determine the frequency of ESBLs in Multi-drug resistant P. aeruginosa from diabetic foot patients. METHOD: Present study's duration was one year and 100 patients with DFU were enrolled...
November 27, 2018: Endocrine, Metabolic & Immune Disorders Drug Targets
Priya Bhusari, Jyotsna Bhatt, Apurva Sood, Ruchikapreet Kaur, Rakhee Vatsa, Ashu Rastogi, Archana Mukherjee, Ashutosh Dash, Bhagwant Rai Mittal, Jaya Shukla
OBJECTIVE: The aim was to evaluate the diagnostic potential of Ga-ubiquicidin positron-emission tomography/computed tomography (PET/CT) in imaging patients with infection. MATERIALS AND METHODS: Ga-NOTA-ubiquicidin (Ga-UBI) was prepared by addition of freshly eluted Ga-chloride from Ge/Ga generator into the NOTA-ubiquicidin vial and incubated at room for 15 min at 90°C. After compounding of the radiopharmaceutical, quality control using instant thin-layer chromatography, culture and endotoxin estimation was performed...
November 21, 2018: Nuclear Medicine Communications
A Searle MOsteo, M J Spink, V H Chuter
Background: Accurate measurement of ankle joint dorsiflexion is clinically important as a restriction has been linked to many foot and ankle pathologies, as well as increased ulcer risk and delayed ulcer healing in people with diabetes. Use of the reliable weight bearing (WB) Lunge test is limited as normal and restricted ranges for WB ankle joint dorsiflexion are not identified. Additionally the extent of WB dorsiflexion restriction that results in clinically adverse outcomes is unclear...
2018: Journal of Foot and Ankle Research
Ilaria Teobaldi, Vincenzo Stoico, Fabrizia Perrone, Massimiliano Bruti, Enzo Bonora, Alessandro Mantovani
Honey has been used as a wound dressing for hundreds of years by ancient civilizations, but only recently it has acquired scientific interest because of its relevant biological properties. In the last decade, indeed, several trials and observational studies have reported that, compared to conventional treatment (e.g. antiseptics, polyurethane film, paraffin gauze, soframycin-impregnated gauze), honey dressings seem to be better in healing time of different types of wounds, including diabetic foot ulcers. However, to date, information about a potential favorable biological effect of honey dressings on diabetic ulcers with exposed tendon are still scarce...
November 16, 2018: Endocrinology, Diabetes & Metabolism Case Reports
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