Matthew K Hoffman, Rebecca G Clifton, Joseph R Biggio, George R Saade, Lynda G Ugwu, Monica Longo, Sabine Z Bousleiman, Kelly Clark, William A Grobman, Heather A Frey, Suneet P Chauhan, Lorraine Dugoff, Tracy A Manuck, Edward K Chien, Dwight J Rouse, Hyagriv N Simhan, M Sean Esplin, George A Macones
IMPORTANCE: A short cervix as assessed by transvaginal ultrasound is an established risk factor for preterm birth. Study findings for a cervical pessary to prevent preterm delivery in singleton pregnancies with transvaginal ultrasound evidence of a short cervix have been conflicting. OBJECTIVE: To determine if cervical pessary placement decreases the risk of preterm birth or fetal death prior to 37 weeks among individuals with a short cervix. DESIGN, SETTING, AND PARTICIPANTS: We performed a multicenter, randomized, unmasked trial comparing a cervical pessary vs usual care from February 2017 through November 5, 2021, at 12 centers in the US...
July 25, 2023: JAMA