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https://www.readbyqxmd.com/read/30419724/clinical-outcomes-of-a-redo-for-a-failed-colorectal-or-coloanal-anastomosis
#1
In Teak Woo, Jun Seok Park, Gyu-Seog Choi, Soo Yeun Park, Hye Jin Kim, In Kyu Park
PURPOSE: Redo surgery in patients with a persistent anastomotic failure (PAF) is a rare procedure, and data about this procedure are lacking. This study aimed to evaluate the surgical outcomes of redo surgery in such patients. METHODS: Patients who underwent a redo anastomosis for PAF from January 2004 to November 2016 were retrospectively evaluated. Data from a prospective colorectal database were analyzed. Success was defined as the combined absence of any anastomosis-related complications and a stoma at the last follow-up...
October 2018: Annals of Coloproctology
https://www.readbyqxmd.com/read/30407464/-clasificaci%C3%A3-n-molecular-del-carcinoma-de-colon-y-recto-una-revisi%C3%A3-n-corta
#2
Leonardo Saúl Lino-Silva, Alberto León-Takahashi, Horacio López-Basave, Alejandro Padilla-Rosciano, Gerardo Miranda-Dévora, Martín Granados-García, Rosa Salcedo-Hernández
Traditionally, carcinoma classifications have been based on clinical or pathological features. However, with the development of molecular biology in recent decades, more tumors are increasingly being genetically studied and, in several of them, molecular classifications have been created (the most widely studied and used is that for breast cancer). Colon and rectum cancer are no exception. In this short review, the evolution of colon and rectum cancer molecular classification is explained and the consensus conclusions on the subject are addressed...
2018: Gaceta Médica de México
https://www.readbyqxmd.com/read/30236076/endometriosis-associated-recto-sigmoid-cancer-a-case-report
#3
Ningning Li, Weixun Zhou, Lin Zhao, Jiaolin Zhou
BACKGROUND: Endometriosis is a relatively common condition in women of reproductive age. Malignant transformation of intestinal endometriosis is a very rare event. We report a case in which a patient with a history of endometriosis underwent surgery for malignant intestinal endometriosis. CASE PRESENTATION: A 55-year-old woman complained of rectorrhagia and intermittent abdominal pain. A neoplasm was revealed by colonoscopy, CT scan and F18-FDG PET/CT of the recto-sigmoidal colon...
September 20, 2018: BMC Cancer
https://www.readbyqxmd.com/read/30213561/mid-term-functional-results-following-surgical-treatment-of-recto-urinary-fistulas-postprostate-cancer-treatment
#4
P-E Theveniaud, N Zafar, A El Hajj, A Germain, L Brunaud, P Eschwege, J Hubert, L Bresler
INTRODUCTION: To evaluate the mid term functional results of patients treated for RUF and to determine an optimal treatment strategy to improve their quality of life. Recto-urinary Fistula (RUF) is a rare complication following prostate cancer treatment, and can have a major impact on patients' quality of life. There is a lack of consensus concerning the best approach and different techniques have been proposed: endoscopic, transrectal, perineal and transperitoneal (open, laparoscopic or robotic)...
September 10, 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29950743/-prevalencia-y-factores-de-riesgo-para-lesiones-premalignas-en-pacientes-menores-de-55-a%C3%A3-os-sometidos-a-colonoscopia-en-un-hospital-de-tercer-nivel
#5
Maricela Jiménez-López, César A García-Romero, Moisés F Rojas-Illanes, José L Martínez-Ordaz
Antecedentes: El cáncer colorrectal es causa importante de mortalidad y la colonoscopia es efectiva para reducir su incidencia y mejorar la supervivencia con la resección de las lesiones precursoras. Objetivo: Determinar la prevalencia, las características y la histología de las lesiones en pacientes < 55 años en un hospital de tercer nivel. Método: Se realizó un estudio retrospectivo y observacional de enero de 2010 a diciembre de 2014 en el Hospital de Especialidades del Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, con el reporte de 555 colonoscopias y los datos clínicos de las historias hospitalarias de los pacientes incluidos en el estudio...
2018: Cirugia y Cirujanos
https://www.readbyqxmd.com/read/29910004/comparative-effectiveness-of-neoadjuvant-chemoradiation-versus-upfront-surgery-in-the-management-of-recto-sigmoid-junction-cancer
#6
Sriram Venigalla, Amit K Chowdhry, Andrzej P Wojcieszynski, John Nicholas Lukens, John P Plastaras, James M Metz, Edgar Ben-Josef, Najjia N Mahmoud, Kim A Reiss, Jacob E Shabason
INTRODUCTION: The optimal management of locally advanced recto-sigmoid cancer is unclear. Although some experts advocate for upfront surgery, others recommend neoadjuvant chemoradiation followed by surgery. We used the National Cancer Database to characterize patterns-of-care and overall survival (OS) associated with these treatment strategies. PATIENTS AND METHODS: Patients with clinical stage II or III recto-sigmoid cancer who underwent surgery with or without adjunctive chemotherapy and/or radiotherapy from 2006 to 2014 were identified, and dichotomized into: (1) upfront surgery, and (2) neoadjuvant chemoradiation cohorts...
September 2018: Clinical Colorectal Cancer
https://www.readbyqxmd.com/read/29800634/robotic-management-of-rectourethral-fistulas-after-focal-treatment-for-prostate-cancer
#7
Luis G Medina, Giovanni E Cacciamani, Angelica Hernandez, Hannah Landsberger, Leo Doumanian, Akbar N Ashrafi, Matthew Winter, Inderbir Gill, Rene Sotelo
OBJECTIVE: To describe our management strategy for rectourethral fistula (RUF) after focal treatment for prostate cancer (PCa) using 2 cases as an example. Almost 50% of RUFs are associated with energy treatment modalities for PCa. The adjacent damage to healthy tissue along with limited pliability of it makes the success of the repair troublesome. There is no standardized approach for these scenarios. MATERIALS AND METHODS: For case 1, an 83-year-old man underwent cryotherapy for PCa...
August 2018: Urology
https://www.readbyqxmd.com/read/29682704/-anastomotic-leakage-after-rectal-cancer-surgery-classification-and-management
#8
Pan Chi, Shenghui Huang
Many studies have focused on the identification of risk factors and prevention of anastomotic leakage following rectal cancer surgery. However, there is little knowledge regarding classification and management of anastomotic leakage in clinic. Herein, we reviewed and summarized the classification and management of anastomotic leakage after rectal cancer surgery. The relevant treatments of anastomotic leakage should be chosen based on patient's manifestation, including general and local reactions, anatomical location, and nature of the leakage (contained or free, controlled or uncontrolled leakage)...
2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29661719/rectal-ulcer-and-pseudomalignant-epithelial-changes-after-prostate-seed-brachytherapy-a-rare-complication-with-a-diagnostic-pitfall
#9
Hwajeong Lee, Natallia Sheuka, Osama El-Kadi, Brian P Murray, Hugh A Fisher, Bhaskar V S Kallakury, Edward C Lee, Ann Boguniewicz, Timothy A Jennings
BACKGROUND: Implant brachytherapy (IBT) is a well-recognized treatment modality for early stage prostate cancer. Rectal ulcer and rectourethral fistula complicating IBT may cause an alteration of the normal anatomic landmarks. In this context, pseudomalignant radiation-induced changes within prostatic epithelium may be misinterpreted as a primary rectal malignancy. Such challenging and misleading findings have not been described, and may not be recognized as such. MATERIALS AND METHODS: We present the clinical and pathologic aspects of two patients who underwent IBT for low stage prostate cancer that was complicated by deep rectal ulcer...
June 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29594584/genital-marginal-failures-after-intensity-modulated-radiation-therapy-imrt-in-squamous-cell-anal-cancer-no-higher-risk-with-imrt-when-compared-to-3dcrt
#10
V Dell'Acqua, J Kobiela, F Kraja, M C Leonardi, A Surgo, M A Zerella, S Arculeo, C Fodor, R Ricotti, M G Zampino, S Ravenda, G Spinoglio, R Biffi, A Bazani, R Luraschi, S Vigorito, P Spychalski, R Orecchia, R Glynne-Jones, B A Jereczek-Fossa
Intensity-modulated radiotherapy (IMRT) is considered the preferred option in squamous cell canal cancer (SCAC), delivering high doses to tumor volumes while minimizing dose to surrounding normal tissues. IMRT has steep dose gradients, but the technique is more demanding as deep understanding of target structures is required. To evaluate genital marginal failure in a cohort of patients with non-metastatic SCAC treated either with IMRT or 3DCRT and concurrent chemotherapy, 117 patients with SCAC were evaluated: 64 and 53 patients were treated with IMRT and 3DCRT techniques, respectively...
March 28, 2018: Medical Oncology
https://www.readbyqxmd.com/read/29551263/-salvage-cryotherapy-of-prostate-cancer-after-failed-external-radiotherapy-and-brachytherapy-morbidity-and-mid-term-oncological-results
#11
MULTICENTER STUDY
A Gevorgyan, J-F Hétet, M Robert, V Duchattelle-Dussaule, L Corno, I Boulay, H Baumert
OBJECTIVE: To study the oncologic and functional results of salvage cryotherapy after failure of external radiotherapy and brachytherapy. MATERIALS AND METHODS: Patients treated by total salvage cryotherapy (3rd generation) in 2 centers (Groupe Hospitalier Saint-Joseph in Paris and Clinique Jule-Verne Nantes) in between January 2008 and April 2016 were included. The biochemical recurrence-free survival (BRFS) was calculated using the Phoenix criteria (PSA>nadir+2ng/mL)...
April 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29540335/-definition-description-clinicopathological-features-pathogenesis-and-natural-history-of-endometriosis-cngof-has-endometriosis-guidelines
#12
REVIEW
B Borghese, P Santulli, L Marcellin, C Chapron
Endometriosis and adenomyosis are histologically defined. The frequency of endometriosis cannot be precisely estimated in the general population. Endometriosis is considered a disease when it causes pain and/or infertility. Endometriosis is a heterogeneous disease with three well-recognized subtypes that are often associated with each other: superficial endometriosis (SUP), ovarian endometrioma (OMA), and deep infiltrating endometriosis (DIE). DIE is frequently multifocal and mainly affects the following structures: the uterosacral ligaments, the posterior vaginal cul-de-sac, the bladder, the ureters, and the digestive tract (rectum, recto-sigmoid junction, appendix)...
March 2018: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/29467549/glucose-transporter-expression-in-the-human-colon
#13
Flavia Merigo, Alessandro Brandolese, Sonia Facchin, Silvia Missaggia, Paolo Bernardi, Federico Boschi, Renata D'Incà, Edoardo Vincenzo Savarino, Andrea Sbarbati, Giacomo Carlo Sturniolo
AIM: To investigate by immunostaining glucose transporter expression in human colorectal mucosa in controls and patients with inflammatory bowel disease (IBD). METHODS: Colorectal samples were obtained from patients undergoing lower endoscopic colonoscopy or recto-sigmoidoscopy. Patients diagnosed with ulcerative colitis ( n = 18) or Crohn's disease ( n = 10) and scheduled for diagnostic colonoscopy were enrolled. Patients who underwent colonoscopy for prevention screening of colorectal cancer or were followed-up after polypectomy or had a history of lower gastrointestinal symptoms were designated as the control group (CTRL, n = 16)...
February 21, 2018: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29394733/-surgical-treatment-for-extremely-elderly-patients-over-90-years-of-age-with-stage-iv-colorectal-cancer-a-report-of-four-cases
#14
Tetsunori Yoshimura, Eisuke Yamamoto, Sakiko Yabe, Taiki Masuda, Hitoshi Sugimoto, Haruya Koshiishi
We report 4 cases ofStage IV colorectal cancer patients over 90 years ofage who received surgical treatment. All of 4 cases were right-sided advanced colon cancer(1 case had also recto-sigmoid advanced cancer)and were received emergency operation. Two cases received resection ofprimary tumors and anastomosis, the other 2 cases received only ileostomy or colostomy. Three cases were able to be discharged from hospital successfully, but unfortunately, we lost one case because of cerebrovascular complication after surgery...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394646/-two-cases-of-non-occlusive-mesenteric-ischemia-that-developed-after-chemotherapy
#15
Takahiro Wada, Kenji Katsumata, Hiroshi Kuwahara, Takaaki Matsudo, Yusuke Murakoshi, Masatoshi Shigoka, Masanobu Enomoto, Tetsuo Ishizaki, Kazuhiko Kasuya, Akihiko Tsuchida
Non-occlusive mesenteric ischemia(NOMI)causes intestinal necrosis due to irreversible ischemia of the intestinal tract despite the absence of organic obstruction in the mesenteric blood vessels. The disease has extremely poor prognosis. We encountered 2 cases of NOMI hypothesized to have developed after chemotherapy; thus, we report these cases considering the available literature. Case 1: A7 9-year-old man. The patient complained of abdominal pain during the first week after introducing docetaxel for local recurrence of prostate cancer...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394605/-a-long-term-disease-free-survival-case-of-synchronous-pulmonary-and-liver-metastasis-of-rectal-cancer-with-systemic-chemotherapy-and-radiofrequency-ablation-therapy-for-liver-metastasis
#16
Masaya Enomoto, Kenji Katsumata, Kenta Kasahara, Hiroshi Kuwabara, Takaaki Matsudo, Masatoshi Shigoka, Masanobu Enomoto, Tetsuo Ishizaki, Akihiko Tsuchida
A 55-year-old woman underwent laparoscopic anterior resection and D2 lymph node dissection for recto-sigmoid colon cancer in November 2014, which was diagnosed as T3N1M1(H3, PUL2), stage IV , for the purpose of preserving the ileus. FOLFOX therapy with panitumumab(Pmab)was started in January 2015.A t the end of 11 courses, pulmonary metastasis changed to CR, and liver metastasis was down-graded to H2 on the CT.Because of the risk of hepatic dysfunction with advanced fatty liver due to chemotherapy and extrahepatic lesions, we chose radiofrequency ablation(RFA)therapy for liver metastasis...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29390545/rare-upper-gastrointestinal-hemorrhage-of-cetuximab-a-case-report
#17
Shi-Jie Duan, Zi-Ming Gao, Peng-Liang Wang, Bao-Cheng Gong, Han-Wei Huang, Lei Luo, Xin Wang, Ya-Nan Xing, Hui-Mian Xu, Fu-Nan Liu
RATIONALE: cetuximab, an epidermal growth factor receptor inhibitor, is a targeted therapeutic regimen of colorectal cancers. Several common adverse effects have been found, such as cutaneous or gastrointestinal toxicity. However, according to the articles had been published, upper gastrointestinal bleeding (UGIB) is considered to be rare and its mechanism remains unclear. PATIENT CONCERNS: In this report, we presented a 42-year-old male patient with advanced recto-sigmoid cancer...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29201511/robot-assisted-radical-perineal-prostatectomy-first-experience-of-15-cases
#18
Volkan Tuğcu, Oktay Akça, Abdulmuttalip Şimşek, İsmail Yiğitbaşı, Selçuk Şahin, Ali İhsan Taşçı
Objective: Minimally invasive techniques are increasingly evolving and preferred to reduce surgical induced morbidity and mortality and minimize the challenges of surgical techniques. Especially radical perineal prostatectomy (RPP) includes some challenges like working in a deep and narrow space and challenging ergonomics for the surgeons. Because of these issues open RPP is still performed in experienced centers. In order to reduce these difficulties, robot- assisted radical perineal prostatectomy (r-RPP) is developed...
December 2017: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29189539/effect-of-continuous-systemic-administration-of-esmolol-on-intraocular-pressure-during-surgery-in-a-sustained-steep-trendelenburg-position
#19
RANDOMIZED CONTROLLED TRIAL
Jin Joo, Jiyoung Kim, Jaemin Lee
PURPOSE: To investigate the effects of continuous systemic administration of esmolol on intraocular pressure (IOP) during laparoscopic and robotic surgeries for recto-sigmoid cancer in a steep Trendelenburg position. MATERIALS AND METHODS: A total of 50 patients undergoing laparoscopic surgery in a steep Trendelenburg position were included. Patients in the esmolol (E) group received a 0.25 mg/kg IV loading dose of esmolol before anesthesia, followed by an infusion of 15 μg/kg/min throughout the operation...
December 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29037748/oncological-results-of-the-educational-rectal-cancer-project-in-spain-10-years-after-its-implementation
#20
MULTICENTER STUDY
Antonio Codina Cazador, Sebastiano Biondo, Eloy Espin Basany, Jose Maria Enriquez-Navascues, Eduardo Garcia-Granero, Jose Vicente Roig Vila, Maria Buxó
INTRODUCTION: The objective of this observational, prospective, multicenter and multilevel study was to evaluate the oncological outcomes (local recurrence, metastasis and overall survival) of the Rectal Cancer Project of the Spanish Association of Surgeons (AEC) 10 years after its initiation, comparing the results with Scandinavian registries. METHODS: The AEC teaching project database includes 17,620 patients to date, of which 4,508 were operated on with a potentially curative resection between March 2006 and December 2010...
December 2017: Cirugía Española
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