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https://www.readbyqxmd.com/read/30324791/optical-coherence-tomography-provides-an-optical-biopsy-of-burn-wounds-in-children-a-pilot-study
#1
Judith Lindert, Kianusch Tafazzoli-Lari, Ludger Tüshaus, Beke Larsen, Anna Bacia, Marie Bouteleux, Tina Adler, Valerie Dalicho, Vasileiadis Vasileidos, Tobias Kisch, Felix Stang, Julia Welzel, Lutz Wünsch
Thermic injuries are among the most severe injuries in childhood. Burn depth is the most relevant prognostic factor, and still its assessment is both difficult and controversial. This diagnostic uncertainty results in repeated wound assessments over a 10-day period and carries a relevant risk for over- and undertreatment. Precise wound assessment would thus be a significant step toward improved care. Optical coherence tomography (OCT) is a noninvasive laser-based technique with a penetration depth of ∼2  mm...
October 2018: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/30324059/burn-in-an-irradiated-prepectoral-breast-reconstruction-a-cautionary-tale
#2
Lauren C Nigro, Michael J Feldman, Nadia P Blanchet
Burns to breast reconstructions, both autologous and implant-based, are well described in the plastic surgery literature. The mechanism has often been contact; however, burns secondary to sun exposure have also been reported. With the increasing number of prepectoral breast reconstructions, including irradiated prepectoral reconstructions, we would like to highlight the increased susceptibility of these reconstructions to thermal and ultraviolet injury. We present the case of a patient who underwent prepectoral implant-based breast reconstruction years after irradiation, who subsequently developed full-thickness injury to her mastectomy flap after minor sun exposure...
August 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/30323021/h-2-s-a-bacterial-defense-mechanism-against-the-host-immune-response
#3
Tracy Toliver-Kinsky, Weihua Cui, Gabor Törö, Seung-Jin Lee, Konstantin Shatalin, Evgeny Nudler, Csaba Szabo
The biological mediator hydrogen sulfide (H2 S) is produced by bacteria and has been shown to be cytoprotective against oxidative stress and to increase the sensitivity of various bacteria to a range of antibiotic drugs. Here we evaluated whether bacterial H2 S provides resistance against the immune response, using two bacterial species that are common sources of nosocomial infections, Escherichia coli and Staphylococcus aureus Elevations in H2 S increased the resistance of both species to immune-mediated killing...
October 15, 2018: Infection and Immunity
https://www.readbyqxmd.com/read/30322740/application-of-hydrosurgery-for-burn-wound-debridement-an-8-year-cohort-analysis
#4
C M Legemate, H Goei, O F E Gostelie, T H J Nijhuis, M E van Baar, C H van der Vlies
INTRODUCTION: During the last decade, the Versajet™ hydrosurgery system has become popular as a tool for tangential excision in burn surgery. Although hydrosurgery is thought to be a more precise and controlled manner for burn debridement prior to skin grafting, burn specialists decide individually whether hydrosurgery should be applied in a specific patient or not. The aim of this study was to gain insight in which patients hydrosurgery is used in specialized burn care in the Netherlands...
October 12, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/30322738/management-of-calciphylaxis-in-a-burn-center-a-case-series-and-review-of-the-literature
#5
David N Dado, Benjamin Huang, Daniel V Foster, Jamison S Nielsen, Jennifer M Gurney, Benjamin D Morrow, Kumar Sharma, Kevin K Chung, Craig R Ainsworth
Calciphylaxis is a rare, necrotizing skin disorder usually associated with kidney disease, but also caused by many other systemic illnesses. This disease is associated with mortality rates as high as 80% at 1year. We present the demographic and clinical data of nine patients with calciphylaxis treated at our burn center over a 10year period. We review the literature on the clinical presentation, pathophysiology, diagnosis and treatment of this rare disease. We propose that these patients be treated similar to patients with thermal burn injury; meaning intensive wound care, surgical management, critical care and physical therapy...
October 12, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/30317973/cytotoxic-effect-of-spondias-cytherea-fruit-extract-in-murine-melanoma-model-in-vivo-and-in-vitro
#6
Feudjio Ndemanou Yolande, Bhattacharyya Sayantan, Ghosh Paramita, Sarkar Deblina, Mouokeu Raymond Simplice, Tume B Christopher, Murmu Nabendu
Cancer is a disease resulting from the deregulation of cell growth control, caused by an interaction between dietary, genetic, and environmental risk factors. Melanoma accounts for about 4% of cancers diagnosed; however they represent 75% of skin cancer-related deaths, with the incidence and death rates having increased globally over the past few decades. Spondias cytherea is a plant from the family Anacardiaceae. Its usage in the treatment of wounds, sores, and burns is reported from several countries, but the anticancer effects of the fruit have not yet been studied...
2018: Journal of Environmental Pathology, Toxicology and Oncology
https://www.readbyqxmd.com/read/30312971/diagnosis-and-treatment-of-invasive-aspergillus-fumigatus-wound-infection-following-subtotal-colectomy-for-perforated-toxic-megacolon-in-an-immunosuppressed-patient
#7
Bryce French, Katherine Mandell, Ryan Martinez
INTRODUCTION: Aspergillus is a rare cause of surgical site infection most often seen in immunocompromised patients undergoing cardiac, transplant, ophthalmologic, or burn operations; an unusual case following a colon resection is presented here. CASE REPORT: The authors report a case of an invasive Aspergillus fumigatus infection following a subtotal colectomy for toxic megacolon. The patient was on antibiotics following the operation and chronic immunosuppression with steroids and infliximab...
October 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30311831/electrosurgery-short-circuit-between-education-and-practice
#8
Frédérique Meeuwsen, Annetje Guédon, Jan Klein, Maarten van Der Elst, Jenny Dankelman, John Van Den Dobbelsteen
INTRODUCTION: Electrosurgery is used in 80% of surgical procedures. The technique allows surgeons to skilfully dissect tissues and achieve haemostasis. Since improper use of electrosurgery can lead to serious adverse events, training is required to potentially reduce the number and severity of these events. In this study we evaluate education and training in electrosurgery for surgical residents. MATERIAL AND METHODS: Residents from six surgical subspecialties in the Netherlands were invited to anonymously complete a digital questionnaire about training, supervision and adverse events regarding electrosurgery...
October 12, 2018: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/30310756/epidemiological-characteristics-and-factors-affecting-length-of-hospital-stay-for-children-and-adults-with-burns-in-zunyi-china-a-retrospective-study
#9
Tao Wang, Chan Nie, Hong Zhang, Xueqin Zeng, Huiting Yu, Zairong Wei, Chenglan Yang, Xiuquan Shi
Objective: Burn wounds are a global public health problem, and a large number of casualties are caused by burns each year. In this study, we explored the epidemiological characteristics associated with burns and the factors affecting the length of hospital stay (LOS) in children and adults with burn wounds. Methods: Records of patients with burns in the Affiliated Hospital of Zunyi Medical University from January 1, 2014 to August 31, 2016 were retrieved. Information on demographic characteristics, mechanism of burns, first treatment received, clinical details of burns, and LOS were extracted from hospital medical records...
2018: PeerJ
https://www.readbyqxmd.com/read/30303596/effect-of-collagenase-ointment-versus-mebo-ointment-on-healing-of-full-thickness-burns-in-mice-by-removing-of-necrotic-tissue
#10
Entesar Hussein Ali, Sinan Saad Adnan
The presence of Necrotic tissue is one of the major problems that effect healing of burn wounds. This study was designed to fined the effectiveness of collagenase versus Mebo ointment on removal of necrotic tissue of burns .Twenty mice randomly assigned and divided into four groups. For group 1 burn wounds were treated with Collagenase ointment only, group 2 burn wounds were treated with Mebo ointment, group 3 burn wounds were treated with white Vaseline alone, group 4 burn wounds were considered as control and left without treatment...
October 10, 2018: Dermatologic Therapy
https://www.readbyqxmd.com/read/30301173/photo-crosslinked-polymeric-matrix-with-antimicrobial-functions-for-excisional-wound-healing-in-mice
#11
Ming-Hsiang Chang, Yu-Ping Hsiao, Chia-Yen Hsu, Ping-Shan Lai
Wound infection extends the duration of wound healing and also causes systemic infections such as sepsis, and, in severe cases, may lead to death. Early prevention of wound infection and its appropriate treatment are important. A photoreactive modified gelatin (GE-BTHE) was synthesized by gelatin and a conjugate formed from the 3,3',4,4'-benzophenone tetracarboxylic dianhydride (BTDA) and the 2-hydroxyethyl methacrylate (HEMA). Herein, we investigated the photocurable polymer solution (GE-BTHE mixture) containing GE-BTHE, poly(ethylene glycol) diacrylate (PEGDA), chitosan, and methylene blue (MB), with antimicrobial functions and photodynamic antimicrobial chemotherapy for wound dressing...
October 5, 2018: Nanomaterials
https://www.readbyqxmd.com/read/30299266/outcomes-in-fournier-s-gangrene-using-skin-and-soft-tissue-sparing-flap-preservation-surgery-for-wound-closure-an-alternative-approach-to-wide-radical-debridement
#12
Travis L Perry, Lindsay M Kranker, Erin E Mobley, Eileen E Curry, R Michael Johnson
INTRODUCTION: Fournier's gangrene (FG) remains a forbidding necrotizing soft tissue infection (NSTI) that necessitates early recognition, prompt surgical excision, and goal-directed antibiotic therapy. Traditionally, surgical management has included wide radical excision for sepsis control, but this management often leaves large, morbid wounds that require complex wound coverage, prolonged hospitalizations, and/or delayed healing. OBJECTIVE: The purpose of this case series is to report the outcomes of FG using a surrogate approach of concurrent debridement of spared skin and soft tissue, negative pressure wound therapy (NPWT), and serial delayed primary closure (DPC)...
October 2018: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/30296361/preparation-of-self-regulating-anti-adhesive-hydrogels-and-their-ability-to-promote-healing-in-burn-wounds
#13
Min Liang, Zhongmin Chen, Fuping Wang, Lan Liu, Runan Wei, Mei Zhang
Few burn dressings can self-regulate the optimal humidity levels that are required for wound healing, while also providing good anti-adhesive properties to prevent damage that can occur when wound dressings are changed. Consequently, a water-soluble carboxymethylcellulose sodium/sodium alginate/chitosan (CMC-Na/SA/CS) composite hydrogel has been developed as a potential burn wound dressing, with orthogonal testing revealing an optimal ratio of CMC-Na, SA, and CS as 2, 3, and 1 wt % for hydrogel preparation, respectively...
October 8, 2018: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/30294349/effect-of-extracorporeal-shock-wave-therapy-on-improving-burn-scar-in-patients-with-burnt-extremities-in-isfahan-iran
#14
Parisa Taheri, Saeid Khosrawi, Mahsa Mazaheri, Mehrdad Adib Parsa, Arghavan Mokhtarian
Background: Pathologic scarring is a common problem after burn injury that has functional and esthetic limitations. Conservative and surgical treatments available for these scars are not always satisfactory. Extracorporeal shock wave therapy (ESWT) is a noninvasive modality that has proven positive effects on burn scars and wound healing in few studies. This study was conducted to evaluate the effects of ESWT on improving burn scar in extremities. Materials and Methods: This study was a prospective quasi-experimental on burn patients with burn scar in their extremities that underwent ESWT sessions once a week for 6 weeks...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/30293363/-clinical-comparative-study-of-pulsed-dye-laser-and-ultra-pulsed-fractional-carbon-dioxide-laser-in-the-treatment-of-hypertrophic-scars-after-burns
#15
N Li, L Yang, J Cheng, J T Han, D H Hu
Objective: To compare the efficacy and safety of pulsed dye laser (PDL) and ultra-pulsed fractional carbon dioxide laser (UFCL) in treating hypertrophic scars after burns. Methods: Two hundred and twenty one patients with hypertrophic scar after burns conforming to the study criteria were admitted to our unit from February 2015 to October 2017, and their data were retrospectively analyzed. Patients were divided into group PDL ( n =122) and group UFCL ( n =99) according to the treatment method. Patients in group PDL were treated with PDL once every 3-4 weeks...
September 20, 2018: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/30293359/-retrospect-of-development-and-progress-over-the-past-60-years-and-going-further-while-carrying-out-practice
#16
P F Liang, P H Zhang
This article briefly describes the establishment and development of Department of Burns and Reconstructive Surgery of Xiangya Hospital of Central South University. Over the past 60 years, our department has achieved great achievements in the treatment of burns by the combination of traditional Chinese medicine with western medicine, treatment of severe burns, and burn wounds repaired by flaps, and established Hunan burn rescue medical collaboration network. With the development of society and the change of disease spectrum, the future development direction of our department mainly focuses on treatment of severe burns, scar prevention, and treatment of acute and chronic wounds...
September 20, 2018: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/30293358/-review-of-sixty-years-of-burn-discipline-in-shanghai-ruijin-hospital
#17
P Y Fang, Q Zhang, Y Liu
Department of Burns and Plastic Surgery of Ruijin Hospital Affiliated to the Medical School of Shanghai Jiao Tong University is derived from the group of severe burn treatment in Surgical Department of Kuang-Ci Hospital in Shanghai in 1958. In three score years, they created and developed distinctive technologies in treatment of massive deep burns, including early eschar excision on deep burn wound by stages and batches, taking the scalp as a donor site, wound covering with the large sheet of allo- or xeno-skin graft with small holes covered by small pieces of autoskin, the Ruijin formula for fluid resuscitation in early stage post burn and the " hibernation remedy" , which achieved actual effects in clinic, and they summed up academically the experiences of their clinical practice and researches...
September 20, 2018: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/30292481/efficacy-and-tolerability-of-a-cocktail-of-bacteriophages-to-treat-burn-wounds-infected-by-pseudomonas-aeruginosa-phagoburn-a-randomised-controlled-double-blind-phase-1-2-trial
#18
Patrick Jault, Thomas Leclerc, Serge Jennes, Jean Paul Pirnay, Yok-Ai Que, Gregory Resch, Anne Françoise Rousseau, François Ravat, Hervé Carsin, Ronan Le Floch, Jean Vivien Schaal, Charles Soler, Cindy Fevre, Isabelle Arnaud, Laurent Bretaudeau, Jérôme Gabard
BACKGROUND: Wound infections are the main cause of sepsis in patients with burns and increase burn-related morbidity and mortality. Bacteriophages, natural bacterial viruses, are being considered as an alternative therapy to treat infections caused by multidrug-resistant bacteria. We aimed to compare the efficacy and tolerability of a cocktail of lytic anti-Pseudomonas aeruginosa bacteriophages with standard of care for patients with burns. METHODS: In this randomised phase 1/2 trial, patients with a confirmed burn wound infection were recruited from nine burn centres in hospitals in France and Belgium...
October 3, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30285752/investigation-of-methicillin-resistant-staphylococcus-aureus-among-clinical-isolates-from-humans-and-animals-by-culture-methods-and-multiplex-pcr
#19
M M Rahman, K B Amin, S M M Rahman, A Khair, M Rahman, A Hossain, A K M A Rahman, M S Parvez, N Miura, M M Alam
BACKGROUND: Staphylococcus aureus is responsible for large numbers of hospital-related and community-acquired infections. In this study, we investigated the presence of S. aureus and methicillin-resistant S. aureus (MRSA) in 100 samples from animals (55 cattle, 36 dogs, and 9 cats) and 150 samples from hospitalized human patients. The samples were collected from healthy and diseased animals and from diseased humans and included milk, wound swab, pus, exudates, nasal swab and diabetic ulcer...
October 3, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/30280840/antimicrobial-susceptibility-profile-of-enterococcus-species-isolated-from-companion-birds-and-poultry-in-the-northeast-of-iran
#20
J Soodmand, T Zeinali, G Kalidari, G Hashemitabar, J Razmyar
Enterococci are Gram-positive facultative anaerobic bacteria commonly found in the gastrointestinal tract of the mammals and birds. These cocci are isolated from urinary tract infections, bacteremia, endocarditis, and burn wounds in humans. The evolution of antibiotic-resistant enterococci raised a problem due to the possibility of the transmission of these organisms between poultry and human. Regarding this, the present study was conducted to evaluate the prevalence of Enterococcus species among companion birds and poultry in the Northeastern of Iran and determine the antibiotic susceptibility profile of enterococci...
September 2018: Archives of Razi Institute
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