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Clinical embryology

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https://www.readbyqxmd.com/read/30528839/elective-single-embryo-transfer-in-the-setting-of-funded-in-vitro-fertilization-two-years-experience-in-an-ontario-hospital-based-fertility-clinic
#1
Sara Ilnitsky, Lynda Hughes, Francis Tekpetey, Basim Abu Rafea, George Vilos, Angelos Vilos
OBJECTIVE: The objective of this study was to assess data from a fertility clinic and identify differences in patient and cycle characteristics, clinical pregnancy rates, and multiple gestation rates before and after fertility treatment funding and a policy of elective single embryo transfer were instituted by the Ontario government to reduce multiple gestations arising from fertility treatment. METHODS: This study was a retrospective database review of clinic and embryology laboratory data for all patients undergoing IVF and ICSI cycles over a 4-year period...
December 6, 2018: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/30522492/open-versus-closed-vitrification-system-of-human-oocytes-and-embryos-a-systematic-review-and-meta-analysis-of-embryologic-and-clinical-outcomes
#2
REVIEW
Hongcai Cai, Jean Damascene Niringiyumukiza, Yamin Li, Qiaohong Lai, Yinzhao Jia, Ping Su, Wenpei Xiang
BACKGROUND: The objective of this study was to carry out a systematic review and meta-analysis of embryologic and clinical outcomes following open versus closed vitrification of human oocytes and embryos. METHODS: An electronic literature search was conducted in main electronic databases up to June 30, 2018 using the following key terms: 'oocyte', 'embryo', 'blastocyst', 'vitrification', 'cryopreservation', 'device', 'survival rate', 'pregnancy rate', etc. A meta-analysis was performed using a random effect model to estimate the value of risk ratios (RRs) and 95% confidence interval (CI)...
December 6, 2018: Reproductive Biology and Endocrinology: RB&E
https://www.readbyqxmd.com/read/30517659/tracking-quality-can-embryology-key-performance-indicators-be-used-to-identify-clinically-relevant-shifts-in-pregnancy-rate
#3
Elizabeth R Hammond, Dean E Morbeck
STUDY QUESTION: Can embryology key performance indicators (KPIs) detect shifts in laboratory performance that precede changes in clinical outcomes? SUMMARY ANSWER: Day 5 usable blastocyst rate (D5BUR) is an important embryology KPI that complements total usable blastocyst rate (TBUR) in its ability to rapidly identify adverse embryology outcomes, prior to changes in clinical outcomes. WHAT IS KNOWN ALREADY: The hypothesis that monitoring performance of an IVF laboratory using statistical process controls (SPCs) can act as an early warning signal of shifts in laboratory conditions is a hypothesis that requires validation...
December 4, 2018: Human Reproduction
https://www.readbyqxmd.com/read/30510876/henle-s-ligament-a-comprehensive-review-of-its-anatomy-and-terminology-over-almost-one-and-a-half-centuries
#4
REVIEW
Raja Gnanadev, Joe Iwanaga, Rod J Oskouian, Marios Loukas, R Shane Tubbs
Henle's ligament was first described by German physician and anatomist, Friedrich Henle, in 1871. This review article will cover Henle's original description of the ligament, historical changes in terminology, embryological studies of the ligament, and the clinical significance of Henle's ligament. This article has a particular focus on the variation in the terminology of this structure and the implications of this.
September 26, 2018: Curēus
https://www.readbyqxmd.com/read/30503291/meningiomas-display-a-specific-immunoexpression-pattern-in-a-rostrocaudal-gradient-an-analysis-of-366-patients
#5
Ege Ülgen, Pınar Kuru Bektaşoğlu, M Aydın Sav, Özge Can, Ayça Erşen Danyeli, Deniz Baycın Hızal, M Necmettin Pamir, Koray Özduman
BACKGROUND: Meningiomas are heterogenous with differences in anatomical, histopathological and clinical characteristics. Such spatial variability in meningioma biology is thought to be due to differences in expression
of critical developmental regulators. We hypothesized that variability in meningioma biology follows gradients as in embryology and tested a cohort of 366 meningiomas for histopathological and immunohistochemical gradients. METHODS: Medical records of 366 patients operated for meningiomas between 2003 and 2016 were retrospectively analyzed for age, gender, anatomical localization, recurrence-free survival, overall survival, histopathological diagnosis and immunohistochemistry findings for six markers: epithelial membrane antigen (EMA), progesterone receptor (PR), CD34, S100, P53 and Ki-67 labeling index (Ki-67)...
November 29, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/30474018/immunohistochemistry-sole-tool-in-diagnosing-a-rare-case-of-primary-vaginal-amelanotic-melanoma
#6
Rashi Garg, Neelam Gupta
We report a rare case of vaginal amelanotic melanoma. Malignant melanomas are cutaneous and extracutaneous tumors that arise from embryological remnants of neural crest cells/melanocytes. Amelanotic melanomas at such rare locations can be misdiagnosed both clinically and radiologically. Therefore, histopathological examination and immunohistochemistry are mandatory for the diagnosis of these tumors. We diagnosed this case using histopathology and confirmed the diagnosis based on the presence of immunohistochemical markers human melanoma black 45 (HMB45) and S-100...
November 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/30472824/segmental-spinal-dysgenesis-redefined
#7
Amarnath Chellathurai, Balaji Ayyamperumal, Rajakumari Thirumaran, Gopinathan Kathirvelu, Priya Muthaiyan, Sivakumar Kannappan
Study Design: Retrospective single institutional observational study. Purpose: Segmental spinal dysgenesis (SSD), a complex spinal dysraphic state caused by notochord malformation disorders, is named after its morphological presentation where a spine segment is dysgenetic, malformed or absent. This study's objective was to examine and reassess SSD imaging findings and correlate them with an embryological explanation. Overview of Literature: Scott and his colleagues defined SSD as segmental agenesis or dysgenesis of the lumbar or thoracolumbar vertebrae and underlying spinal cord...
November 27, 2018: Asian Spine Journal
https://www.readbyqxmd.com/read/30466646/arterial-anomalies-of-the-middle-ear-a-pictorial-review-with-clinical-embryologic-and-imaging-correlation
#8
REVIEW
Anne Marie Sullivan, Hugh D Curtin, Gul Moonis
The differential diagnosis of a red and/or pulsatile retrotympanic mass includes aberrant internal carotid artery, persistent stapedial artery (PSA), glomus tympanicum, and dehiscent jugular bulb. By recognizing the features of aberrant internal carotid artery and PSA on high-resolution computed tomography, these entities can be assessed by the radiologist. PSA is further classified by type because each type demonstrates a unique set of imaging features in addition to features common to all types. Although rarely encountered, it is important to reliably and consistently detect these anomalies because failure to do so can lead to disastrous surgical outcomes...
February 2019: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/30454807/congenital-thoracic-aortic-disease
#9
REVIEW
Luis A Landeras, Jonathan H Chung
Congenital abnormalities of the thoracic aorta encompass a variety of disorders with variable clinical manifestations ranging from asymptomatic to life threatening. A variety of imaging modalities are available for the evaluation of these anomalies with computed tomography (CT) commonly preferred due to its excellent spatial resolution and rapid acquisitions, avoiding the need of general anesthesia or even sedation. We review the embryology, imaging findings, and associations of multiple congenital thoracic aorta malformations with emphasis in the role of CT angiography in the evaluation of these pathologies...
January 2019: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/30445440/anatomical-variations-of-the-aortic-arch-branches-in-a-sample-of-chinese-cadavers-embryological-basis-and-literature-review
#10
Yumin Qiu, Xiaoxin Wu, Zhuokai Zhuang, Xiaozhi Li, Lei Zhu, Cijun Huang, Hongjie Zhuang, Mingjian Ma, Feng Ye, Jing Chen, Zhiying Wu, Xiaopei Yu, Mingjie An, Rui Chen, Junyu Chen, Lizhi Guan, Hanyi Sang, Yuyang Ye, Yueyin Han, Zhuokai Chen, Han Qin, Haoshuai Zhu, Yingying Zhou, Prince L M Zilundu, Dazheng Xu, Lihua Zhou
OBJECTIVES: The aim of this study is to determine the incidence and explore the types of aortic arch branch variations found in our cadavers. METHODS: The types and incidence of aortic branch variations in 120 cadavers were analysed after careful dissection. RESULTS: One hundred and six of 120 cadavers had normal aortic arch branches and gave rise to usual branches, namely the brachiocephalic trunk, the left common carotid artery and the left subclavian artery...
November 15, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/30423868/the-memory-of-the-heart
#11
REVIEW
Marco Cirillo
The embryological development of the heart is one of the most fascinating phenomena in nature and so is its final structure and function. The various ontogenetic passages form the evolutive basis of the final configuration of the heart. Each key step can be recognized in the final features, as the heart maintains a kind of "memory" of these passages. We can identify the major lines of development of the heart and trace these lines up to the mature organ. The aim of this review is to identify these key parameters of cardiac structure and function as essential elements of the heart's proper functioning and bases for its treatment...
November 11, 2018: Journal of Cardiovascular Development and Disease
https://www.readbyqxmd.com/read/30391938/ependyma-lined-canal-with-surrounding-neuroglial-tissues-in-lumbosacral-lipomatous-malformations-relationship-with-retained-medullary-cord
#12
Nobuya Murakami, Takato Morioka, Takafumi Shimogawa, Nobutaka Mukae, Satoshi Inoha, Takakazu Sasaguri, Satoshi O Suzuki, Koji Iihara
BACKGROUND: An ependyma-lined canal with surrounding neuroglial tissues can be present in lumbosacral lipomatous malformations; however, the precise embryological significance is still unclear. METHOD: Six out of 50 patients with lipomatous malformations had ependymal structures. We retrospectively analyzed the clinical, neuroradiological, and histological findings of these patients to demonstrate the relationship with the embryological background of the retained medullary cord (RMC), which normally regresses, but was retained here because of late arrest of secondary neurulation...
November 2, 2018: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/30391270/-congenital-cysts-and-fistulas-on-the-neck-in-adults
#13
Stanislas Ballivet de Régloix, Olga Maurin, Anna Crambert, Louise Genestier, Gratien Bonfort, Yoann Pons
Cervical congenital malformations are relatively common in children. They can also be found in adults. The embryological development of the cervical region is closely related to the branchial clefts. This must be a diagnosis made by elimination; a cervical tumor must evoke the diagnosis of cancer. A cutaneous fistula or a cervical tumor, chronic or recent appearance in an inflammatory context, are the clinical signs. The thyroglossal duct cysts and the second branchial clefts cysts are the most common causes of median and lateral cervical cysts, respectively...
October 31, 2018: La Presse Médicale
https://www.readbyqxmd.com/read/30387331/towards-a-multidimensional-scientific-approach-to-improve-clinical-practices-for-infertility-treatment
#14
Yu-Hang Zhu, Fan Qu
Polycystic ovary syndrome (PCOS) is the most common metabolic and endocrine disorder in women, leading to infertility. However, there is no general agreement concerning how to diagnose and treat PCOS. The Rotterdam consensus statement from the European Society of Human Reproduction and Embryology/American Society for Reproductive Medicine, the Chinese diagnostic criteria and consensus statement, and the clinical practice guideline from the Endocrine Society in the USA are widely recognized. Guidance has been provided for clinical practice based on a comparative analysis of the above three practice guidelines or consensus statements (Wang et al...
2018: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/30373582/outcome-after-hepatic-resection-for-isolated-non-colorectal-non-neuroendocrine-liver-metastases-in-100-patients-the-role-of-the-embryologic-origin-of-the-primary-tumor
#15
Philipp Anton Holzner, Frank Makowiec, Andrea Klock, Torben Glatz, Stefan Fichtner-Feigl, Sven Arke Lang, Hannes Philipp Neeff
BACKGROUND: The indication for hepatic resection (HR) in patients suffering from liver metastases (LM) other than colorectal and neuroendocrine tumors is one focus of current multidisciplinary, oncologic considerations. This study retrospectively analyzes outcome after HR for non-colorectal, non-neuroendocrine (NCNNE) LM in the absence of distant or extrahepatic metastases. METHODS: We included 100 consecutive patients undergoing HR for isolated NCNNE LM from a prospective database in our institution, including postoperative follow-up...
October 29, 2018: BMC Surgery
https://www.readbyqxmd.com/read/30366459/postponing-pregnancy-through-oocyte-cryopreservation-for-social-reasons-considerations-regarding-clinical-practice-and-the-socio-psychological-and-bioethical-issues-involved
#16
REVIEW
Mara Simopoulou, Konstantinos Sfakianoudis, Panagiotis Bakas, Polina Giannelou, Christina Papapetrou, Theodoros Kalampokas, Anna Rapani, Ekaterini Chatzaki, Maria Lambropoulou, Chrysoula Lourida, Efthymios Deligeoroglou, Konstantinos Pantos, Michael Koutsilieris
Oocyte freezing for 'social reasons' refers to women of reproductive age who are aiming to prolong, protect and secure their fertility. The term emerged to describe application of the highly promising technique, namely vitrification on oocytes retrieved through controlled ovarian stimulation (COS) from women intending to preserve their fertility for social reasons. These women opt to cryopreserve their oocytes at a point in their life when they need to postpone childbearing on the grounds of so called 'social' reasons...
October 25, 2018: Medicina
https://www.readbyqxmd.com/read/30366174/small-bowel-obstruction-secondary-to-left-paraduodenal-hernia-a-case-report-and-literature-review
#17
Youssef Sleiman, Alaa El-Kheir, Melody El-Khoury, Omar Hamdach, Layla Ismail, Mustafa Allouch
INTRODUCTION: Internal hernias are uncommon and are defined by the protrusion of a viscus through intraperitoneal defects. Left paraduodenal hernias (LPDH) are the most common type of congenital internal hernia (CIH). We report a clinical case of a patient with a small bowel obstruction (SBO) due to a LPDH. CASE PRESENTATION: An elderly patient, with negative surgical history, presented to the emergency room with abdominal pain and vomiting. Clinical and radiologic investigations were consistent with SBO due to an internal hernia...
October 12, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/30341015/the-styloglossus-muscle-a-critical-landmark-in-onclogy-and-mandibular-preservation-surgery-for-squamous-cell-carcinoma-of-the-lateral-oropharynx
#18
O Laccourreye, R K Orosco, F Rubin, F C Holsinger
GOAL: To document the role of the styloglossus muscle (SG) in the oncologic staging and mandibular preservation surgery for squamous cell carcinoma of the lateral oropharynx (SCCLO). METHOD: Based on a search conducted within the Pubmed, Embase, and Cochrane databases, using the key words SG muscle, parapharyngeal space and oropharynx, the authors discuss the embryology, physiology, anatomy and radiology of this muscle as well as its role in the oncologic staging and mandibular preservation surgery of SCCLO...
October 16, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/30338176/tendinous-inscriptions-of-the-rectus-abdominis-a-comprehensive-review
#19
REVIEW
Rabjot Rai, Lilian C Azih, Joe Iwanaga, Marios Loukas, Martin Mortazavi, Rod J Oskouian, R Shane Tubbs
The rectus abdominis muscles are interrupted by tendinous inscriptions, which typically appear as fibrous bands crossing the muscle. The current literature on tendinous inscriptions is scarce; hence, this review will provide a detailed overview of their anatomical description, including their variation, embryology, comparative anatomy, and clinical application. Understanding the anatomy and function of the tendinous inscription assists in providing clinical relevance and in guiding reconstructive surgeons in their surgical planning and design...
August 4, 2018: Curēus
https://www.readbyqxmd.com/read/30332331/neuroscience-and-greek-mythology
#20
Ioannis Karakis
This article highlights the major reflections of ancient Greek mythology in modern neuroscience. An analysis of ancient Greek texts and medical literature using the MeSH term mythology was performed to identify mythological references pertaining to neuroscience. The findings are discussed in relation to etymology, early conceptualization of the nervous system structure and function, incipient characterization of neuropsychiatric disease, and philosophical stance to the practice of medicine in ancient Greece...
October 17, 2018: Journal of the History of the Neurosciences
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