Yannik Vollmuth, Nicola Jungbäck, Tatiana Mögele, Friederike Schmidt-Graf, Silke Wunderlich, Mareike Schimmel, Camilla Rothe, Leonhard Stark, Jürgen Schlegel, Georg Rieder, Thomas Richter, Tina Schaller, Dennis Tappe, Bruno Märkl, Kaspar Matiasek, Friederike Liesche-Starnecker
Borna disease virus 1 (BoDV-1) was just recently shown to cause predominantly fatal encephalitis in humans. Despite its rarity, bornavirus encephalitis (BVE) can be considered a model disease for encephalitic infections caused by neurotropic viruses and understanding its pathomechanism is of utmost relevance.Aim of this study was to compare the extent and distribution pattern of cerebral inflammation with the clinical course of disease, and individual therapeutic procedures.For this, autoptic brain material from seven patients with fatal BVE was included in this study...
April 30, 2024: Emerging Microbes & Infections