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Jean O'Brien-Louis
No abstract text is available yet for this article.
November 6, 2018: Transfusion and Apheresis Science
Svetoslav Nanev Slavov, Katia Kaori Otaguiri, Melina Lellis Bianquini, Hellen Tayana Oliveira Bitencourt, Marcia Cristina Munhoz Chagas, Domingos Sávio de Souza Guerreiro, Luiz Tadeu Moraes Figueiredo, Dimas Tadeu Covas, Simone Kashima
Background: Chikungunya virus, an arbovirus that belongs to the Alphavirus genus of the Togaviridae family, causes a febrile illness accompanied by rash and arthralgia. It is estimated that during outbreaks, the prevalence of Chikungunya virus RNA in viremic blood donations varies between 0.4 and 2.1%; therefore, this virus may be transmitted by transfusion. In Brazil, Chikungunya virus has been claimed to cause extensive outbreaks, however, the seroprevalence of anti-Chikungunya virus IgG among Brazilian blood donors is unknown...
October 2018: Hematology, transfusion and cell therapy
Guilherme Rossi Assis-Mendonça, André Henrique Crepaldi, Márcia Torresan Delamain, Adriana Helena Moreira, Felipe D'Almeida Costa, Vladmir Cláudio Cordeiro de Lima, Cármino Antonio de Souza, Fernando Augusto Soares, José Vassallo
Objective: Follicular and mantle cell lymphoma are low-grade B-cell malignancies that lack good responses to chemoimmunotherapy. This study aimed to assess retrospectively clinicopathological features and to determine independent prognostic factors for follicular and mantle cell lymphoma patients treated at two Brazilian medical centers: the Hematology and Hemotherapy Center of the Universidade Estadual de Campinas (Unicamp), a public university hospital, and AC. Camargo Cancer Center, a specialized cancer center...
October 2018: Hematology, transfusion and cell therapy
Marcella Martins de Vasconcelos Vaena, Luiz Anastacio Alves
No abstract text is available yet for this article.
December 1, 2018: Advances in Physiology Education
Caroline Maria Igrejas Lopes, Marília Cabral Cavalcanti, Ana Cláudia Alves E Luna, Kátia Maria Gonçalves Marques, Maria José Rodrigues, Valdenice Aparecida DE Menezes
Sickle cell anemia, a genetic disease caused by a mutation in the beta-globin gene, can present oral manifestations such as delayed tooth eruption and hypomineralized enamel and dentin. The aim of the present study was to evaluate the prevalence and severity of developmental defects of enamel (DDE) and delayed tooth eruption in children with sickle cell anemia. The sample comprised 56 male and female children with sickle cell anemia aged 6 to 12 years and treated at the Hematology and Hemotherapy Center of Pernambuco, Brazil...
August 13, 2018: Brazilian Oral Research
Melissa P Santana, Reinaldo Souza-Santos, Andrea S de Almeida
BACKGROUND: Despite the intensification of Chagas disease control in Brazil, around 1980s and 1990s, the transmission still occurs. The aim of this study was to identify the factors associated with Chagas disease among blood donors in Piaui State, Brazilian Northeast Region from 2004 to 2013. METHODOLOGY: Records of 597 blood donors from Management System in Hemotherapy Services and Laboratory Environment Manager System of Piaui were studied. Sociodemographic variables and serological tests results for Chagas disease's confirmation were analyzed using adjusted multiple logistic regression and odds ratio (OR) evaluation...
November 2018: Journal of Infection and Public Health
Chester Andrzejewski, Lynne O'Hearn, Joan Rock, Kelly Passanisi, Lynn Eaton, Alexander Knee, Susmitha Edappallath, Michael Merola, Darlene Cloutier, Paul Visintainer, Vandita Johari
BACKGROUND: Suspected transfusion reaction (STR) investigations are foundational for biovigilance. Diagnostic evaluations performed by blood banks may prolong turnaround times (TATs) for final STR results reporting. We identified a quality improvement opportunity using diagnostic testing reflex algorithms and our hospital's patient electronic health record to enhance TATs regarding one aspect of STR results reporting. STUDY DESIGN AND METHODS: We conducted a descriptive quality improvement study of reported STR cases investigated by our hospital's blood bank from March 1, 2014, to December 31, 2016, using data obtained from consult reports/quality improvement databases examining the number and types of diagnostic algorithm reflex activations performed and the TATs for an electronic provisional diagnosis reporting (PDXR) related to them...
July 2018: Transfusion
M K B Souza
BACKGROUND AND OBJECTIVES: This article aims to characterize some elements that define the organizational models of healthcare actions in the field of blood and blood products. MATERIALS AND METHODS: This exploratory and qualitative study was carried out based on a documentary survey complemented by interviews with key informants of hemotherapy services from three regional territories in Spain and Brazil. RESULTS: It was evidenced demographic, territorial and organizational characteristics, as well as on instruments, resources and individuals involved in the planning, organization and implementation of services and actions in the area...
May 21, 2018: Vox Sanguinis
Wolfgang Korte, Sacha S Zeerleder
No abstract text is available yet for this article.
April 2018: Transfusion Medicine and Hemotherapy
Fatima Zanin, Maria Stella Moreira, Ana Clara Fagundes Pedroni, Mateus Windlin, Ana Paula Brugnera, Aldo Brugnera Júnior, Marcia Martins Marques
BACKGROUND: Interdental papilla is of major importance to patients' orofacial aesthetics, especially regarding anterior teeth as part of the smile's harmony. Loss of gingival tissue, which constitutes interdental papilla, forms what in odontology is called black spaces. This loss, besides affecting the smile's aesthetics, also provokes phonetic and functional damage. OBJECTIVE: The objective of the authors is to present the result of three clinical cases treated with an innovative technique called hemolasertherapy, which stimulates growth of gingival papilla and thus permanently fills in the black spaces...
April 2018: Photomedicine and Laser Surgery
Federico J Kaufer, Liliana A Carral, Matías T Messina, María Vanessa Schneider, Miriam Méndez, Lourdes Herrera, Cristina B Freuler, Ricardo A Durlach
A prevalence study of antibodies anti Toxoplasma gondii in voluntary blood donors who attended the hemotherapy service at the Hospital Alemán during the first four months of the years 1997, 2007 and 2017 was carried out and the results were compared to the study carried out in 1967. The sera where processed with the Sabin Feldman Dye Test. The global average seroprevalence in 1967 was 67.0% (CI95%, 64.4%-69.6%); in 1997, 35.0% (CI95%, 33.3%-38.3%); in 2007, 31.9% (CI95%, 29.6%-34.2%) and in 2017, 21.2% (CI95%, 19...
2017: Medicina
I Pekrul, G Wittmann, P Möhnle
Based on the German Transfusion Law, the periodically updated guidelines "Richtlinien zur Gewinnung von Blut und Blutbestandteilen und zur Anwendung von Blutprodukten" ("Hämotherapierichtlinien") are intended to provide the current knowledge and state of the art of blood transfusion practice in Germany. The novel update 2017 contains relevant changes for blood donation, especially the extension of the exclusion period of persons at risk for sexually transmitted HBV, HCV and HIV diseases to 12 months...
January 2018: Der Anaesthesist
Thomas Frietsch, Daffyd Thomas, Michael Schöler, Birgit Fleiter, Martin Schipplick, Michael Spannagl, Ralf Knels, Xuan Nguyen
BACKGROUND: Compared to blood component safety, the administration of blood may not be as safe as intended. The German Interdisciplinary Task Force for Clinical Hemotherapy (IAKH) specialized registry for administration errors of blood products was chosen for a detailed analysis of reports. METHODS: Voluntarily submitted critical incident reports (n = 138) from 2009 to 2013 were analyzed. RESULTS: Incidents occurred in the operation room (34...
August 2017: Transfusion Medicine and Hemotherapy
Kathy Khoy, Minh Vu Chuong Nguyen, Dominique Masson, Béatrice Bardy, Christian Drouet, Marie-Hélène Paclet
BACKGROUND: Transfusion-related acute lung injury (TRALI) is a major complication of hemotherapy that may occur after the transfusion of any blood type component. Several clinical reports have suggested the presence of anti-HLA antibodies in the blood product. This study sought to examine the role of anti-HLA-A2 antibodies in polymorphonuclear neutrophil (PMN) activation and thus in endothelial permeability. STUDY DESIGN AND METHODS: PMN activation was assessed by both nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase) activity and reactive oxygen species (ROS) production...
July 2017: Transfusion
Wolfgang Korte, Marco Cattaneo
No abstract text is available yet for this article.
April 2017: Transfusion Medicine and Hemotherapy
Y Fomenko, V Sirota, I Omarova, N Kabildina, A Amanov
93 patients with LABC (T2N1-2M0, T3N0-2M0) at the age from 35 to 75 years were included in the trial. With 2 stage - 60 patients, with the third stage - 33 patients. All patients were randomized into 3 groups: The I control group (n=36) received 4 courses of neoadjuvant chemotherapy according to AC-protocol (doxorubicin 50 mg/m2, cyclophosphan-500 mg/m2 on day 1, repeated every three weeks) followed by radical mastectomy, 4 courses of adjuvant chemotherapy (АС), radiotherapy and hormone therapy if indicated...
March 2017: Georgian Medical News
Sakurao Hiraki, Kou Kanesada, Toshio Harada, Kousuke Tada, Shintaro Fukuda
A 76-year-old woman was referred to our hospital because of an abdominal tumor in September 2009. An irregularly shaped large tumor was detected in the right subcostal abdominal cavity on computed tomography, and was diagnosed as advanced gallbladder cancer without distant metastasis following further examination. We then performed a laparotomy. The tumor had invaded directly into the descending portion of the duodenum and transverse colon. We performed a curative resection of the tumor macroscopically. Pathological findings were moderately differentiated tubular adenocarcinoma derived from gallbladder cancer(T3N0M0, Stage III )...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
Olivier Garraud
No abstract text is available yet for this article.
February 2017: Transfusion and Apheresis Science
Marc Maegele, Giuseppe Nardi, Herbert Schöchl
PURPOSE OF REVIEW: This review presents a synopsis of best current knowledge with reference to the updated German and European guidelines and recommendations on the management of severe trauma hemorrhage and trauma-induced coagulopathy as well as a viscoelastic-based treatment algorithm based upon international expert consensus to trigger the administration of hemostatic agents and blood products. RECENT FINDINGS: Uncontrolled hemorrhage and trauma-induced coagulopathy are the major causes for preventable death after trauma and early detection and aggressive management have been associated with improved outcomes...
April 2017: Current Opinion in Anaesthesiology
Aline G Monich, Tiago W Dantas, Karla B Fávero, Paulo T R Almeida, Eliane C Maluf, Carolina De M Capeletto, Renato M Nisihara
INTRODUCTION: Development of technologies to reduce transfusion risks of infectious diseases is a major characteristic of hemotherapy. Thus, each donation undergoes clinical and serological screening tests to ensure the donated blood do not offer risks to the receiver. OBJECTIVE: Evaluate the prevalence of positive serology in blood donations rejected by Hemobanco (Curitiba - PR) in the period ranging from January 2003 to December 2012. METHODOLOGY: During the period studied, we observed the total number of donations and its division according to gender...
April 2017: Transfusion and Apheresis Science
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