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Risk pregnancies

Stefanie Parks, Matthew K Hoffman, Shivaprasad S Goudar, Archana Patel, Sarah Saleem, Sumera Aziz Ali, Robert L Goldenberg, Patricia L Hibberd, Janet Moore, Dennis Wallace, Elizabeth M McClure, Richard J Derman
OBJECTIVE: To describe the association of maternal anaemia with maternal, foetal and neonatal outcomes. DESIGN: Prospective cohort study. SETTING: Rural India and Pakistan. POPULATION: Pregnant women residing in the study catchment area. METHODS: We performed an analysis of a prospective pregnancy registry wherein haemoglobin is commonly obtained as well as maternal, foetal and neonatal outcomes through 42 days post-delivery...
December 16, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
Bharathi Geetha, Chinnaraju Sukumar, Eswaran Dhivyadeepa, Janardhana Kumar Reddy, Vellingiri Balachandar
Autism spectrum disorder is a neurodevelopmental disorder and the cause of autism is still unclear. The aim of this study was to investigate the association of socioeconomic, environmental, pregnancy and newborn-related risk factors among children with autism spectrum disorders. This was a population-based case-control study. The study included 55 children with autism spectrum disorder and 55 age and sex matched typically developing normal children (TD) between 3 and 12 years. Several socio-economic factors, environmental factors, pregnancy related, natal, post-natal factors and the first noticed signs by the parents were analyzed...
December 15, 2018: Acta Neurologica Belgica
Carla Assaf-Balut, Nuria García de la Torre, Alejandra Duran, Manuel Fuentes, Elena Bordiú, Laura Del Valle, Cristina Familiar, Johanna Valerio, Inés Jiménez, Miguel A Herraiz, Nuria Izquierdo, María J Torrejon, Maria Ángeles Cuadrado, Isabel Ortega, Francisco J Illana, Isabelle Runkle, Paz de Miguel, Inmaculada Moraga, Carmen Montañez, Ana Barabash, Martín Cuesta, Miguel A Rubio, Alfonso L Calle-Pascual
AIMS: The aim of the study was to evaluate the effect of a Mediterranean diet (MedDiet), enhanced with extra virgin olive oil (EVOO) and nuts, on a composite of adverse maternofoetal outcomes of women with normoglycemia during pregnancy. METHODS: This was a sub-analysis of the St Carlos gestational diabetes mellitus Prevention Study. Only normoglycemic women were analysed (697). They were randomized (at 8-12th gestational weeks) to: standard-care control group (337), where fat consumption was limited to 30% of total caloric intake; or intervention group (360), where a MedDiet, enhanced with EVOO and pistachios (40-42% fats of total caloric intake) was recommended...
December 14, 2018: Annals of Nutrition & Metabolism
Aimee Grant, Melanie Morgan, Dunla Gallagher, Dawn Mannay
BACKGROUND: Moral judgements are commonly directed towards mothers through reference to health behaviour in pregnancy, and working-class mothers are particularly subject to this moral gaze. AIM: To gain an in-depth understanding of the health issues affecting 10 low income pregnant women from deprived areas of south Wales, UK. METHODS: Participants completed visual activities (timelines, collaging or thought bubbles and dyad sandboxing) prior to each interview...
December 12, 2018: Women and Birth: Journal of the Australian College of Midwives
Shuichi Suetani, Abdullah Mamun, Gail M Williams, Jake M Najman, John J McGrath, James G Scott
Low physical activity is a major public health concern. There has been extensive research examining the role of physical activity as a potentially modifiable risk factor for the onset of mental illness. However, fewer studies have reported how mental disorders affect future physical activity. Using data from a large birth cohort, the current study explored the association between the longitudinal course of common mental disorders (affective disorders, anxiety disorders, and substance use disorders, as well as any common mental disorder) and subsequent physical activity status among young adults living in Australia...
December 6, 2018: Journal of Psychiatric Research
G Ducarme, A C Pizzoferrato, R de Tayrac, C Schantz, T Thubert, C Le Ray, D Riethmuller, E Verspyck, B Gachon, F Pierre, F Artzner, B Jacquetin, X Fritel
INTRODUCTION: The objective of these clinical practice guidelines was to analyse all of the interventions during pregnancy and childbirth that might prevent obstetric anal sphincter injuries (OASIS) and postnatal pelvic floor symptoms. MATERIAL AND METHODS: These guidelines were developed in accordance with the methods prescribed by the French Health Authority (HAS). RESULTS: A prenatal clinical examination of the perineum is recommended for women with a history of Crohn's disease, OASIS, genital mutilation, or perianal lesions (professional consensus)...
December 12, 2018: Journal of Gynecology Obstetrics and Human Reproduction
Rebecca Peters, Mario Stevenson
BACKGROUND: Since its sudden appearance and link to microcephaly in 2015, the number of PubMed references for Zika virus (ZIKV) has risen from 181 to 5,163, as of writing, with a vast proportion focused on the consequences of ZIKV infection during pregnancy. This level of attention underlies increased demand for sensitive and specific diagnostic tools able to assess risk to an unborn child, as well as to understand the dynamics and consequences of viral persistence. AIM: Review the expanding knowledge on ZIKV persistence and diagnostic challenges and summarize current advancements in detection...
December 12, 2018: Clinical Microbiology and Infection
M Vahdaninia, H Mackenzie, T Dean, S Helps
No abstract text is available yet for this article.
December 12, 2018: Annals of Allergy, Asthma & Immunology
Hamideh Bayrampour, Mike Zahradnik, Sarka Lisonkova, Patti Janssen
Cannabis is the most commonly used illicit drug among general and pregnant populations. Despite recommendations to abstain from cannabis use, its use is increasing during the perinatal period. In this integrative review, we aim to understand women's perspectives about the health aspects of perinatal cannabis use. The following databases were searched: MEDLINE, PsycInfo, EMBASE, and CINAHL. We included quantitative and qualitative studies with a primary focus on perinatal cannabis use. The methodological quality of the included studies was appraised using appropriate checklists...
December 12, 2018: Preventive Medicine
Dana E Lowry, Daniel J Corsi, Ruth Rennicks White, Mary Guo, Andrea Lanes, Graeme Smith, Marc Rodger, Shi Wu Wen, Mark Walker, Laura Gaudet
BACKGROUND: Low molecular weight heparin (LMWH), an anticoagulant, is the recommended drug for thromboprophylaxis and treatment of venous thromboembolism (VTE) in pregnancy. During pregnancy, LMWH is routinely prescribed to mothers with an increased risk of VTE or with a history of thrombosis. Although clinical reports of larger offspring born to women administered LMWH have been noted, no studies to date have evaluated or associated the use of LMWH and large for gestational age (LGA) infants...
December 14, 2018: Journal of Thrombosis and Haemostasis: JTH
Ai-Wu Shi, Xiao-Feng Shen, Hong-Juan Ding, Yao-Qiu Liu, Li Meng, Bill Kalionis
BACKGROUND: Gestational diabetes mellitus is strongly related to the risk of pancreatic cancer in pregnant women, but gestational diabetes can precede a diagnosis of pancreatic cancer by many years. Women with a history of gestational diabetes showed a relative risk of pancreatic cancer of 7.1. Pancreatic adenocarcinoma is one of the most common malignancies associated with thromboembolic events. A clinical study showed that thromboembolic events were detected in 36% of patients diagnosed as having pancreatic cancer...
December 15, 2018: Journal of Medical Case Reports
Surani Fernando, Santhosh Kumar, Mahmoud Bakr, David Speicher, Rodney Lea, Paul A Scuffham, Newell W Johnson
OBJECTIVES: This study explored the association of children's salivary characteristics, past caries experience, birth weight, and reported maternal prenatal vitamin and mineral supplementation with the dental untreated decay of the child. METHODS: This cross-sectional study, a sub-study of Griffith University Environments for Healthy Living birth cohort study, was conducted on 174 mother-child dyads. Mother's prenatal usage of vitamin and mineral supplements; child's birthweight; salivary pH, buffering capacity, and levels of salivary MS and LB were explored as risk indicators...
December 14, 2018: Journal of Public Health Dentistry
Madeleine U Shalowitz, Christine Dunkel Schetter, Marianne M Hillemeier, Vernon M Chinchilli, Emma K Adam, Calvin J Hobel, Sharon Landesman Ramey, Maxine Reed Vance, Patricia O'Campo, John M Thorp, Teresa E Seeman, Tonse N K Raju
OBJECTIVE:  Allostatic load (AL) represents multisystem physiological "wear-and-tear" reflecting emerging chronic disease risk. We assessed AL during the first year postpartum in a diverse community sample with known health disparities. METHODS:  The Eunice Kennedy Shriver National Institute for Child Health and Human Development Community Child Health Network enrolled 2,448 predominantly low-income African-American, Latina, and White women immediately after delivery of liveborn infants at ≥20 weeks' gestation, following them over time with interviews, clinical measures, and biomarkers...
December 14, 2018: American Journal of Perinatology
Louopou Rosalie Camara, Tye Elaine Arbuckle, Helen Trottier, William Donald Fraser
BACKGROUND:  Little is known about the association between bisphenol A (BPA) or triclosan (TCS) exposure and hypertension in pregnancy. OBJECTIVE:  To investigate potential associations between maternal urinary concentrations of BPA or TCS and gestational hypertension (GH) and preeclampsia. STUDY DESIGN:  Among 1,909 pregnant women participating in the maternal-infant research on environmental chemicals (MIREC) study, urinary concentrations of BPA and TCS were measured in the first trimester by liquid chromatography-tandem mass spectrometry using isotope dilution...
December 14, 2018: American Journal of Perinatology
Diesa Oliveira Pinheiro, Bruna Boff Varisco, Marcelo Brandão da Silva, Rafaela Silva Duarte, Graciele Dequi Deliberali, Carlos Roberto Maia, Mirela Foresti Jiménez, Patrícia El Beitune
OBJECTIVE:  To evaluate the accuracy of the diagnosis of fetal heart diseases obtained through ultrasound examinations performed during the prenatal period compared with the postnatal evaluation. METHODS:  A retrospective cohort study with 96 pregnant women who were attended at the Echocardiography Service and whose deliveries occurred at the Complexo Hospitalar Santa Casa de Porto Alegre, in the state of Rio Grande do Sul, Brazil. Risk factor assessment plus sensitivity and specificity analysis were used, comparing the accuracy of the screening for congenital heart disease by means of obstetrical ultrasound and morphological evaluation and fetal echocardiography, considering p  < 0...
December 14, 2018: Revista Brasileira de Ginecologia e Obstetrícia
Emmanuel Bassily, Cameron Bell, Sean Verma, Nidhi Patel, Aarti Patel
The maternal cardiovascular system undergoes profound changes to support the increasing demands of fetal growth during pregnancy. An accumulating body of evidence has shown that common pregnancy complications, including gestational diabetes mellitus, preeclampsia, low birth weight, and preterm delivery, can be associated with future cardiovascular adverse events in mothers. Factors such as glucose metabolism, hyperlipidemia, inflammatory markers, large and small vessel stiffness/functionality have been linked with these pregnancy conditions...
December 11, 2018: American Journal of Medicine
Hyun Sun Ko, Jeong Ha Wie, Sae Kyung Choi, In Yang Park, Yong-Gyu Park, Jong Chul Shin
PURPOSE: To examine the competing risks of stillbirth versus infant death and to evaluate the optimal time of delivery in the population of small for gestational age (SGA) and non-SGA late preterm and term fetuses. METHODS: This was a retrospective national cohort study of all singleton births between 34 0/7 and 42 6/7 weeks of gestation using the Korean vital statistics (n = 2,106,159). We compared the risk of infant mortality with a composite of fetal-infant mortality risk that would occur after expectant management for one additional week and evaluated the optimal time of delivery, in SGA and non-SGA pregnancies...
2018: PloS One
Christina C Lawson, Candice Y Johnson, Feiby L Nassan, Thomas H Connor, James M Boiano, Carissa M Rocheleau, Jorge E Chavarro, Janet W Rich-Edwards
Findings from this cross-sectional study indicate a need for expanded training in safe handling practices. ABSTRACT: Background: Many antineoplastic (chemotherapeutic) drugs are known or probable human carcinogens, and many have been shown to be reproductive toxicants in cancer patients. Evidence from occupational exposure studies suggests that health care workers who have long-term, low-level occupational exposure to antineoplastic drugs have an increased risk of adverse reproductive outcomes...
December 12, 2018: American Journal of Nursing
Raigam J Martinez-Portilla, Montse Pauta, Ameth Hawkins-Villarreal, Marta Rial-Crestelo, Fernanda Paz Y Miño, Irene Madrigal, Francesc Figueras, Antoni Borrell
OBJECTIVE: To establish the added value of chromosomal microarray analysis (CMA) above normal karyotyping to assess the genetic causes of stillbirth. METHODS: A systematic search was performed to identify relevant studies published in English and Spanish using PubMed, SCOPUS and ISI Web of Knowledge databases, The Cochrane Library and PROSPERO database for meta-analysis, without publication time restrictions. Case-series of fetal losses ≥ 20 weeks of gestation, assessed by CMA with at least 5 subjects analyzed...
December 14, 2018: Ultrasound in Obstetrics & Gynecology
Gianluca Tolva, Rosamaria Silipigni, Aida Quarenghi, Patrizia Vergani, Silvana Guerneri, Donatella Milani
Circulating cell-free DNA, having no procedural risk of miscarriage, is the most suitable sample for a noninvasive prenatal testing (NIPT). Here we report on a boy, who came to our attention for hypotonia and psychomotor delay when he was 16 months old. During the pregnancy his mother performed a NIPT that resulted compatible with the presence of trisomy 18. A confirmatory invasive procedure has been proposed, but not performed, because the family preferred to follow a conservative line. A series of ultrasound excluded the presence of any major malformations...
December 13, 2018: Journal of Obstetrics and Gynaecology Research
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