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Orbit tumor

Thibaut Cassou-Mounat, Marie Luporsi, Virginie Huchet, Nina Jehanno
Malignant conjunctival melanoma is a rare tumor. A 46-year-old woman with a history of locally recurrent left conjunctival melanoma was followed by F-FDG PET/CT. Four years after the local recurrence treated by orbital exenteration, the follow-up PET/CT scan showed an incidental intense FDG uptake mass infiltrating the gallbladder associated with a low uptake of an infracentimetric pulmonary nodule. The patient was completely asymptomatic with no sign of local recurrence. Laparoscopic cholecystectomy was performed, and histopathologic findings were consistent with gallbladder metastasis of melanoma...
December 3, 2018: Clinical Nuclear Medicine
Carol H Yan, Charles C L Tong, Mrudula Penta, Vishal S Patel, James N Palmer, Nithin D Adappa, Jayakar V Nayak, Peter H Hwang, Zara M Patel
OBJECTIVES/HYPOTHESIS: Inverted papillomas (IPs) are benign tumors of the sinonasal tract with a malignant transformation potential. Predicting the transformation propensity of IPs and corresponding risk factors has long been a challenge. In this study, we aimed to use radiographic findings on magnetic resonance imaging (MRI) and computed tomography (CT) to help differentiate IP from IP-transformed squamous cell carcinomas (IP-SCC). STUDY DESIGN: Retrospective cohort study...
December 4, 2018: Laryngoscope
Awat Yousefiazar, Mohsen Hassanzadazar
Eyelid reconstructions are considered challenging surgical procedures, which are mostly performed due to trauma, tumor resections, and congenital defects. Several techniques can be used to reconstruct the lower eyelid defects. In this study, the authors aimed to introduce a new single-step technique for the reconstruction of medium-sized lower eyelid defects while preventing ectropion. A modified nasojugal flap was designed and harvested after making a complete incision. A dermal extension from the nasolabial area was added to the end of the nasojugal flap...
December 4, 2018: Facial Plastic Surgery: FPS
Roee Birnbaum, Naama Yosha-Orpaz, Miri Yanoov-Sharav, Dvora Kidron, Hila Gur, Keren Yosovich, Tally Lerman-Sagie, Gustavo Malinger, Dorit Lev
Protein arginine methyltransferase 7 (PRMT7) is a member of a family of enzymes that catalyze the transfer of methyl groups from S-adenosyl-l-methionine to nitrogen atoms on arginine residues. Arginine methylation is involved in multiple biological processes, such as signal transduction, mRNA splicing, transcriptional control, DNA repair, and protein translocation. Currently, 10 patients have been described with mutations in PRMT7. The shared findings include: hypotonia, intellectual disability, short stature, brachydactyly, and mild dysmorphic features...
December 4, 2018: American Journal of Medical Genetics. Part A
Sabrina Bergeron, Debra-Meghan Sanft, Pablo Zoroquiain, Evangelina Esposito, Bryan Arthurs, Miguel N Burnier
Purpose: Granuloma annulare (GA) is a rare clinical entity that does not classically arise from the peri-orbital area in adults. The purpose of this case report is to present a 69-year-old female with GA of the orbit. As well, the pathological and immunohistochemical features of these tumors will be discussed. Observations: One case of GA of the orbit was identified from a tertiary ophthalmology referral centre. Clinical and histopathological features of the case were reviewed...
March 2019: American Journal of Ophthalmology Case Reports
Di Chen, Xiaowei Liu, Ying Li, Hui Guan, Fuquan Zhang
Background: Radiotherapy (RT) has widely been used to treat ocular tumors, yet the impact of orbital radiation to the meibomian gland has rarely been studied. Our study aims at evaluating the bilateral meibomian gland structure and function 12 months after unilateral orbital RT in patients with ocular tumors. Methods: An observational case-control study. A total of 10 eyes 12 months after unilateral orbital RT, 10 contralateral eyes, and 10 normal controls were enrolled...
2018: Journal of Ophthalmology
Fairooz P Manjandavida, Shaifali Chahar, Brijal Dave
A 19-year-old female student presented with painless, progressive proptosis in the right eye for the past six months causing significant cosmetic blemish and double vision. Clinical evaluation revealed normal visual acuity, normal pupillary reflex, severe proptosis, and dystopia. Orbital imaging revealed a heterogeneous mass in superior orbit displacing the globe inferiorly and causing extensive bony erosion of frontal bone superiorly and invading the frontal sinus. Excision biopsy was performed with en-bloc removal of the tumor...
November 29, 2018: Orbit
Tsutomu Nomura, Daisuke Maki, Fumihiko Matsumoto, Taisuke Mori, Seichi Yoshimoto
Lacrimal sac tumors are rare and difficult to diagnose. We present a case of coexisting lacrimal sac adenocarcinoma and transitional cell carcinoma in a 73-year-old woman who presented with swelling of the inner canthus. Biopsy identified the growth as an adenocarcinoma. After dissection of the lacrimal carcinoma via a lateral rhinotomy, histopathologic examination confirmed the adenocarcinoma and identified a coexisting transitional cell carcinoma. A recurrence developed, but only of the adenocarcinoma component...
October 2018: Ear, Nose, & Throat Journal
Carolyn L Mulvey, Eleanor P Kiell, Mark D Rizzi, Adva Buzi
OBJECTIVE: The microbiology of pediatric complicated acute rhinosinusitis (ARS) has evolved, and our current understanding of pathogenic organisms is limited. The objectives of this study are to describe the incidence of pathogens causing complicated ARS requiring surgical intervention at our institution over a 10-year period as well as their associated treatment outcomes. STUDY DESIGN: Retrospective cohort study. SETTING: A single tertiary care children's hospital...
November 27, 2018: Otolaryngology—Head and Neck Surgery
John Oommen, Hafiz Mohammed, Shanker Ayyappan Kutty, Abraham Mammen, Kader Kalathingal, Chandrabose Vellani Thamunni, Anand Sivadasan, Santhy Nair
Teratomas are rare congenital neoplasms. Head and neck locations of the tumor are uncommon with combined intracranial and extracranial extensions being even more rare. The authors present a case of teratoma involving the temporal, buccal, maxillary, orbital and extending to the intracranial regions, which was successfully managed by surgical resection.
November 22, 2018: Journal of Craniofacial Surgery
F Banaz, I Edem, I D Moldovan, S Kilty, G Jansen, F Alkherayf
Introduction  Surgical treatment of petrous apex chondrosarcoma is challenging due to the location of the tumor. Using an endoscopic technique for tumor resection is favored since it provides a minimally invasive approach. Case Presentation  A 57 years old female was admitted for acute onset of left abducens nerve palsy and occasional headache mainly on the left side of the retro-orbital area with some radiation to the left occiput. Magnetic resonance imaging (MRI) and computed tomography (CT), at the time of admission, were showed lytic lesion on the left petrous apex and left part of the clivus...
October 2018: Journal of Neurological Surgery Reports
Michael W Ruff, Sani H Kizilbash
We present a case of bilateral synchronous orbital muscle infiltration of extra-neural glioblastoma metastases with evidence of focal treatment response. The orbital infiltration was preceded by evidence of leptomeningeal disease, and followed by further symptomatic perineural spread of tumor along the second and third division of the trigeminal nerve and into the masticator space.
November 21, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Aslam Hentati, Nidhal Matar, Hadhemi Dridi, Soufien Bouali, Hafedh Jemel
Cavernous hemangioma of the orbit (CHO) is a benign slow-growing lesion of intracanal space. Bilateral orbital cavernous hemangiomas are extremely rare, so that only a few cases have been reported in scientific literature. A 54-year-old patient presented a 1-year history of impaired visual acuity of the left eye. Physical examination showed a left axial propotosis. Orbital magnetic resonance imaging showed a 28 mm diameter intraconal space mass of the left orbit, as well as another 11 mm diameter lesion in the right eye, in the superomedial extraconal space...
October 2018: Asian Journal of Neurosurgery
Tao Xu, Yong Yan, Hongxiang Wang, Juxiang Chen
This operative video demonstrates a transclinoid-transcavernous approach for the resection of a cavernous sinus hemangioma. The patient is a 42-yr-old female who presented with headache and blurred vision. Magnetic resonance imaging (MRI) demonstrated an enhancing mass in the right-side cavernous sinus and sella. The patient underwent an orbito-zygomatic craniotomy, extradural anterior clinoidectomy and transcavernous approach for tumor resection. Removal of the orbital roof, lateral orbital wall, zygomatic arch and anterior clinoid process with a high-speed drill was performed...
November 15, 2018: World Neurosurgery
Sungsoon Hwang, Yoon-Duck Kim, Debrelle Lou Siapno, Yeon-Lim Suh, Kyung In Woo
Fibromyxomas are rare tumors that are not commonly seen in the orbit. The authors present a case of orbital fibromyxoma. A 42-year-old male presented with proptosis of the right eye that began 1 month prior. Magnetic resonance imaging revealed the presence of an orbital mass in the right eye, with low signal intensity on T1-weighted images and heterogeneous high-signal intensity on T2-weighted images. The patient underwent excisional biopsy of the orbital tumor through a Krönlein approach. The tumor originated from the inferior rectus muscle...
November 15, 2018: Journal of Craniofacial Surgery
J Halička, T Haličková, L Vargončíková, M Fedorová, K Kapitánová, M Sičák, A Kališ, P Žiak
A seventysix-year-old female was acutely admitted to the Eye Clinic of the University Hospital in Martin with a 1 month history of impaired central and peripheral vision on the right eye. At the admission patient`s right eye VA was fingers at 20 cm, the left eye had a central vision preserved. Magnetic resonance of the brain and orbits demonstrated cystic tumor expansion in the sellar region with compression of optic chiasm and optic nerves (more on the right side), in diff. dg. as cystic macroadenoma of the pituitary gland...
2018: Ceská a Slovenská Oftalmologie
Z Y Wang, W L Yang, D J Li, W Chen, Q Zhao, Y F Li, R Cui, L Shen, W B Wei
Objective: To analyze the ultrasound diagnosis and differential diagnosis of medium and small choroidal melanomas. Methods: It was a retrospective case series study. Thirty-six cases (36 eyes) with medium or small choroidal melanoma were collected between January 2016 and January 2017 in Beijing Tongren Hospital, including 16 males and 20 females aged (50±12) years old. All tumors' apical heights were within 5 mm and the largest basal diameter was within 15 mm. Sixty-nine cases (69 eyes) with choroidal hemangioma, including 45 males and 24 females aged (45±11) years old, and 16 cases (19 eyes) with choroidal metastasis, including 4 males and 12 females aged (50±11) years old, of equal size were also analyzed as differential diagnosis...
November 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
Tawfiq Khoury, David Jang, Ricardo Carrau, Neal Ready, Ian Barak, Ralph Abi Hachem
BACKGROUND: Cancers of the paranasal sinuses are rare tumors that tend to be aggressive and usually are diagnosed at an advanced stage. Despite being rare, these tumors include a wide spectrum of histological subtypes with different biological behaviors. Choosing the optimal treatment modalities and analyzing the different oncological outcomes is therefore challenging. This study aims to evaluate the role of induction chemotherapy prior to definitive local therapy for sinonasal malignancies...
November 9, 2018: International Forum of Allergy & Rhinology
Nawal Habib, Kimberly Lessard
Superior ophthalmic vein thrombosis is extremely rare and is often associated with orbital inflammation/infection, systemic/local tumors, hypercoagulable states, autoimmune conditions, and rarely carotid cavernous fistula. Clinical features include abrupt onset of painful proptosis, chemosis, ophthalmoplegia, and diminished visual acuity. Prompt diagnosis and treatment are essential to prevent permanent blindness. Management options for this medical emergency include antibiotics, steroids, and/or anticoagulation...
2018: Case Reports in Oncological Medicine
Akihide Kondo, Osamu Akiyama, Mario Suzuki, Hajime Arai
Although orbital tumors involving the optic nerve are rare, it is well-known that they are very likely to cause serious visual impairment in a patient. Unfortunately, at present, there are no effective interventions that can reliably preserve visual function while controlling tumor growth into intracranial spaces. To ensure visual function of the non-affected side, transection of the optic nerve together with the tumors involved is necessary in some cases. For this procedure large craniotomy and orbital unroofing are commonly utilized...
November 5, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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