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Orbit tumor

Swathi Kaliki, Sai Divya Jajapuram, Arpita Maniar, Dilip K Mishra
PURPOSE: To study the incidence, treatment, and outcome of ocular and periocular tumors in patients with xeroderma pigmentosum (XP) DESIGN: Retrospective case series METHODS: Setting: Single-institutional study PATIENTS: 120 patients with XP INTERVENTION: Excisional biopsy, Enucleation, Orbital exenteration; Main outcome measures: Occurrence of eyelid or ocular surface tumor, globe salvage, locoregional and systemic metastasis, and death RESULTS: The mean age at presentation was 19 years...
October 15, 2018: American Journal of Ophthalmology
Kun Wang, Feidan Yu, Keng Chen, Huanjiang Niu, Yirong Wang, Shuxu Yang, Xiujun Cai
RATIONALE: Osteoblastoma is an uncommon primary bone tumor that involves any part of the skeleton. But its occurrence in the skull is extremely rare. PATIENTS CONCERNS: A 30-year-old female was admitted to our hospital, because of the mass in the right frontal region with the history of headache for 3 years without nausea or vomiting. DIAGNOSIS: Initial differential diagnoses included hemangiopericytoma, atypical intraosseous meningioma, calvarial osteosarcoma, fibrous dysplasia, and histiocytosis, based on the results of enhanced CT and MRI...
October 2018: Medicine (Baltimore)
Yuta Murakami, Shinya Jinguji, Yugo Kishida, Masahiro Ichikawa, Taku Sato, Masazumi Fujii, Jun Sakuma, Fumi Murakami, Kiyoshi Saito
We report a case of a young male who received multiple surgical treatments for repeated recurrence of skull base mesenchymal chondrosarcoma (MC). When the patient was 18 years old, we subtotally removed the skull base MC and he was treated with stereotactic radiosurgery for remnant tumors in the left cavernous sinus. After 30 months, we removed residual tumors that had regrown partially, via combined endonasal endoscopic and orbitozygomatic approaches. Over the next 65 months, the patient refused radical resection, and received six salvage surgeries, two stereotactic radiotherapies, and five stereotactic radiosurgeries for repeated recurrence...
October 2018: NMC Case Report Journal
Lindsay A McGrath, Hardeep Singh Mudhar, Sachin M Salvi
Optic nerve hemangioblastoma (ONH) is a rare tumor that is usually unilateral and most commonl occurs in the context of von Hippel-Lindau (VHL) disease. Differential diagnosis is based on clinical history and imaging. Magnetic resonance imaging with gadolinium enhancement is the most useful imaging modality as it can reveal flow voids and an absence of dural attachment, differentiating ONH from other more commonly encountered optic nerve tumors. ONH are usually well-circumscribed vascular lesions composed of stromal cells and vascular endothelial cells...
October 12, 2018: Survey of Ophthalmology
Nickisa M Hodgson, Ashley A Campbell, Jessica R Chang, Adelita Vizcaino, Charles Eberhart, Monica S Pearl, Timothy J McCulley
Orbital invasion of pituitary adenomas has been previously reported. In this report, the authors describe a 71-year-old female with a prolactinoma that presented with invasion of and apoplexy within the orbit. The patient underwent exenteration, followed by rapid tumor recurrence and growth. Given the hemorrhagic nature of the tumor, she subsequently underwent preoperative embolization and surgical resection. This case is notable in that it illustrates both apoplexy of a pituitary tumor within the orbit and the benefit of presurgical embolization...
October 9, 2018: Ophthalmic Plastic and Reconstructive Surgery
Bifica Lyngdoh, Jaya Mishra, Biswajit Dey, Caleb Harris, Arindom Kakati, Zachariah Chowdhury, Rintu Marak, Evarisalin Marbaniang
Orbital location of extraskeletal osteosarcoma is extremely rare with only 4 cases reported so far in the English literature. We present the case of a 32-year-old female who presented with proptosis and complete loss of vision of the left eye. Contrast-enhanced computed tomography scan showed a densely calcified lobulated lesion in the left optic nerve showing strong enhancement. A left fronto-occipito-zygomatic osteotomy was conducted and a greyish brown tumor was identified. Histopathological and immunohistochemical examination of the curetted material revealed it to be extraskeletal osteosarcoma...
September 2018: Ocular Oncology and Pathology
Akshay G Nair, Swaranjali S Gore, Amol Y Ganvir, Namrata G Adulkar, Indumati Gopinathan, Anuradha K Murthy, Nayana A Potdar, Chhaya A Shinde
Aim: To describe and review the clinical, radiological, and histopathological characteristics of an orbital perivascular epithelioid cell tumor (PEComa). Methods: A systematic review of clinical records, radiological investigations, microscopic features, and immunohistochemical characteristics was done. Results: A 9-year-old female child presented with a year-long history of a large orbital mass associated with painless, progressive proptosis of the right eye...
September 2018: Ocular Oncology and Pathology
Frederick A Jakobiec, Natalie Homer, Fouad R Zakka, Hugh D Curtin, Aaron Fay
Objective: To distinguish between a multifocal orbital lymphoid tumor and a major simulator represented by a diffuse lymphaticovenous malformation. Methods: We performed a comparison of clinical and radiographic (magnetic resonance imaging [MRI]) findings of these two disparate entities and demonstrated how a misdiagnosis can be prevented. Results: Orbital lymphoid tumors develop in adults at around 60 years of age, whereas extensive lymphaticovenous malformations are generally detected in the first decade...
September 2018: Ocular Oncology and Pathology
Paul T Finger, Puneet Jain, Sri Krishna Mukkamala
PURPOSE: Evaluate Super-Thick Amniotic Membrane Graft(ST-AMG) for ocular surface reconstruction. DESIGN: Retrospective, interventional case series. METHODS: SETTING: Single center, clinical practice POPULATION: Selected patients with typically large ocular surface abnormalities that required reconstruction. INTERVENTION: Surgical insertion of ST-AMG for reconstruction or repair of the ocular surface. MAIN OUTCOME MEASURES: Intraoperative handling, graft position at 1 week post-implantation, graft dissolution at 3-weeks, epithelialization of the ocular surface and symblepharon...
October 9, 2018: American Journal of Ophthalmology
Teresa A Ferreira, P Saraiva, S W Genders, M V Buchem, G P M Luyten, J-W Beenakker
PURPOSE: Orbital inflammation can be idiopathic or in the context of a specific disease and it can involve different anatomical orbital structures. On imaging, inflammatory disease is frequently mistaken for infection and malignant tumors, and its underlying cause is often not determined. Through this article we aim to improve orbital inflammation diagnosis and underlying inflammatory diseases recognition. METHODS: The imaging protocols and characteristics of orbital inflammation were reviewed...
October 11, 2018: Neuroradiology
Sally Nguyen, Sylvie Nadeau
Background Osteomas are rare benign and slow-growing osteogenic tumors mainly involving frontal and ethmoid sinuses. Objectives The primary objective of our study is to present the management of cases of giant frontal sinus osteomas. Secondarily, we describe our modified unilateral osteoplastic flap approach without obliteration to remove these osteomas. Methods Retrospective chart review at a tertiary academic center ("Hôpital de l'Enfant-Jésus") from July 2006 to October 2016. Demographics characteristics, tumor characteristics, presenting symptoms, frontal sinus surgery technique (osteoplastic flap, endoscopic surgery, or a combination of both), and outcomes of giant frontal sinus osteomas (≥30 mm) were recorded...
October 11, 2018: American Journal of Rhinology & Allergy
H-J Welkoborsky, S K Plontke
For removal of tumors and foreign bodies from the orbit, for treatment of severe inflammatory diseases, and for repositioning of bone fragments following fractures or during reconstruction of the bony orbit, several different surgical approaches are available. During the past decade, improved understanding of the pathology and pathophysiology of particular orbital diseases, advancements in clinical endoscopy and microscopy, the introduction of modern imaging techniques for preoperative visualization of pathologic findings, modern approaches to orbital reconstruction, as well as developments in adjuvant therapy have led to a reduction in invasiveness and development of the modern minimally invasive surgical approaches to the orbit usually used today...
October 10, 2018: HNO
Jonathan K Ramsey, James L Chen, Lynn Schoenfield, Raymond I Cho
Undifferentiated pleomorphic sarcoma is a malignancy of mesenchymal origin, which was previously known as malignant fibrous histiocytoma. It is known to occur on rare occasion as a primary orbital tumor, but no known cases of metastatic orbital involvement have been reported since 2002, when the reclassification of these tumors took place. The authors report a patient who presented with a metastasis to the left orbit 2 years after undergoing treatment of a high-grade undifferentiated pleomorphic sarcoma of the right thigh...
September 27, 2018: Ophthalmic Plastic and Reconstructive Surgery
Albert Sii-Hieng Wong, Vincent Boon-Hean Chen
Introduction: This study describes a technique using gravity for guidance in stereotactic brain biopsy. This will be especially useful in hospitals where the stereotactic equipment is unavailable. Objectives: The aim of this study is to describe the technique, develop a formula to define its limits of accuracy, and report on its clinical application. Methods: Using the positioning laser grid lines on the computed tomography scanner, a small metallic marker is placed on the scalp at the intended biopsy site...
July 2018: Asian Journal of Neurosurgery
Bommie Florence Seo, Kyo Joon Kang, Sung-No Jung, Jun Hee Byeon
Skeletal cavernous hemangiomas are rare, benign tumors that may involve the supraorbital rim and orbital roof. However, such involvement is extremely rare. We report a case of skeletal cavernous hemangioma of the frontal bone involving the orbital roof and rim. En bloc excision and reconstruction, using a calvarial bone graft for the orbital roof and rim defect, was performed. It is important not only to perform total excision of skeletal cavernous hemangiomas, but to properly reconstruct the defects after the total excision since several complications can arise from an orbital roof and rim defect...
September 2018: Archives of Craniofacial Surgery
Abbas Bagheri, Kourosh Shahraki, Mehdi Tavakoli
Cavernous hemangioma (CH) is the most common benign tumor of the orbit which can expand the bony orbit by gradual growth of a large tumor. In this article, the authors report a 28-year-old man presented with a longstanding unilateral proptosis secondary to a huge orbital CH which also caused optic disc deformation and bone erosions in the adjacent orbital walls. The optic disc deformities resolved after the tumor removal.
October 1, 2018: Journal of Craniofacial Surgery
Inês Coutinho, Marco Marques, Rui Almeida, Sofia Custódio, Teresa Simões Silva, Fernanda Águas
Orbital metastasis is a rare event, and metastatic disease affecting the extraocular muscles is an even less frequent complication of solid tumors. Herein, we report an unusual case of ptosis as the initial presentation of an invasive breast cancer. A 68-year-old woman presented with III and VI partial nerve paresis, secondary to a compressive retrobulbar mass. Magnetic resonance imaging revealed an infiltrative lesion involving the extraocular muscles. Tissue biopsy yielded a result compatible with metastasis to the orbit, with immunohistochemistry analysis suggesting breast as the primary organ...
September 2018: Journal of Breast Cancer
João Pedro Perez Gomes, José de Ribamar Castro Veloso, Albina Messias de Almeida M Altemani, Carlos Takahiro Chone, João Mauricio Carrasco Altemani, Claudio Fróes de Freitas, Carmen Silvia Passos Lima, Paulo Henrique Braz-Silva, Andre Luiz Ferreira Costa
BACKGROUND The clivus is a depression in the anterior occipital bone of the skull base, posterior to the dorsum sellae, at the junction with the sphenoid bone. Chordoma is a rare tumor arising from embryonic remnants of the notochord and can be locally aggressive with a tendency to recur. The optimal management of this rare tumor remains controversial. A report of a case of recurrent chordoma of the clivus is presented to illustrate the value of volumetric three-dimensional (3-D) reconstruction with computed tomography (CT) and magnetic resonance imaging (MRI) to determine optimal surgical management...
October 2, 2018: American Journal of Case Reports
Timothy C Blood, Fausto J Rodriguez, Norris Nolan, Murugappan Ramanathan, Shaun C Desai
Calcifying pseudoneoplasms of the neuroaxis (CAPNON) are rare, benign tumors of unknown histogenesis. CAPNON generally are found intracranially or within the spinal column in symptomatic patients. We present the case of an asymptomatic patient with an incidentally discovered right anterior cranial fossa mass with extension through the posterior and anterior table of the right frontal sinus and right superior orbital roof. Open biopsy was performed via a transblepharoplasty incision with pathological diagnosis of CAPNON...
July 2018: Journal of Neurological Surgery Reports
Samantha Seitter, Zachary D Goodman, Theodore M Friedman, Timothy R Shaver, George Younan
Introduction: Reactive lymphoid hyperplasia (RLH) is a rare and benign lesion found in organs of the gastrointestinal tract, skin, lung, orbit, and more rarely in the liver. Due to its similar appearance on imaging, it is hard to differentiate from primary liver malignancies. The following is a case report of a patient presenting with a suspicious liver lesion found to be RLH associated with primary biliary cirrhosis (PBC), after surgical resection. Presentation of Case: A 54-year-old woman presented with nonspecific abdominal pain, and her workup included axial imaging of the abdomen that showed a suspicious lesion in her liver...
2018: Case Reports in Surgery
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