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Perforator imaging

Caleb Tsetse, Shazia Rahat Chaudhry, Feraas Jabi, Jennifer Nicole Taylor
Acute diverticulitis is a painful condition of the gastrointestinal tract that results from sudden inflammation of one or more diverticula in the bowel wall. Right-sided acute diverticulitis, such as cecal diverticulitis, is uncommon diagnosis that can be easily misdiagnosed as acute appendicitis as it shares similar clinical presentation. An unusual complication of right-sided acute diverticulitis such as perforated cecal diverticulitis has different management from acute appendicitis. Thus, definitive diagnosis of this clinical condition with imaging is crucial to optimal management...
January 2019: Radiology Case Reports
Ramya Rangarajan
Aim: With the advent of computed tomography (CT)-based brachytherapy, it is possible to view the appropriate placement of the applicator within the uterine canal and detect uterine perforation. In this study, the incidence of suboptimal placement of the intracavitary applicator and the resulting dosimetric impact were analyzed and compared with a similar set of ideal applicator placement. Materials and Methods: CT datasets of 282 (141 patients) high dose rate brachytherapy insertions between January and April 2016 were analyzed...
July 2018: Journal of Medical Physics
Felix Simon Christian Quade, Beate Preitz, Nikola-Michael Prpic
OBJECTIVE: The bleaching, clearing and handling of tiny specimens with soft tissue and cuticular components for confocal laser scanning microscopy is difficult, because after cuticle bleaching and tissue clearing the specimens are virtually invisible. We have adjusted the design of the specimen container described by Smolla et al. (Arthropod Struct Dev 43:175-81, 2014) to handle tiny specimens. RESULTS: We describe a perforated and anodised aluminium slide that was designed to hold the distal tips of the pedipalp appendages of the spider Parasteatoda tepidariorum during clearing, and that can then be used directly for confocal laser scanning microscopy...
October 10, 2018: BMC Research Notes
Jiyoung Hwang, Seong Sook Hong, Hyun-Joo Kim, Yun-Woo Chang, Bo Da Nam, Eunsun Oh, EunJi Lee
Tuberculous peritonitis is one of the most common causes of exudative ascites, especially in the young, and is an important cause of extra-pulmonary disease. However, tuberculous peritonitis is challenging to diagnose because there are no pathognomonic clinical features or imaging findings. Therefore, it is commonly misdiagnosed as another type of peritoneal disease, especially so in elderly patients with malignant disease. In this report, we described two cases of tuberculous peritonitis that were observed after intestinal perforation in elderly patients with malignancies...
May 2018: Revista da Associação Médica Brasileira
Jianhua Peng, Yue Wu, Jinwei Pang, Xiaochuan Sun, Ligang Chen, Yue Chen, Jiping Tang, John H Zhang, Yong Jiang
OBJECTIVE: The endovascular filament-perforation model turned out to become the most popular one for the reproduction of prominent pathophysiological features observed after human subarachnoid haemorrhage (SAH). However, few studies have considered methods that may minimize surgically induced injury. This study described an improved and simplified surgical procedure in which a single clip is placed at the external carotid artery (ECA). METHOD: Male C57BL/6 mice were given either a classic endovascular filament SAH model, improved endovascular filament SAH model or sham injury...
October 8, 2018: Brain Injury: [BI]
Siyuan Liao, Zhezhi Deng, Yuge Wang, Ting Jiang, Zhuang Kang, Sha Tan, Yilong Shan, Yan Zou, Zhengqi Lu
Purpose: Perforating Artery Infarcts (PAIs) can be divided into two subtypes based on their etiologies: branch Atheromatous Disease (BAD) and Lacunar Infarct (LI). Recent studies have shown that while both subtypes can be caused by large artery lesions, the different mechanisms that underlie their development are not clear. This study was designed to use High-Resolution Magnetic Resonance Imaging (HRMRI) to explore the differences that contribute to the occurrence of these two subtypes in large artery lesions in the anterior circulation...
2018: Frontiers in Neurology
Maho Shibata, Eisuke Ishizaki, Ting Zhang, Masanori Fukumoto, Alma Barajas-Espinosa, Tong Li, Donald G Puro
P2X7 receptor/channels in the retinal microvasculature not only regulate vasomotor activity, but can also trigger cells in the capillaries to die. While it is known that this purinergic vasotoxicity is dependent on the transmembrane pores that form during P2X7 activation, events linking pore formation with cell death remain uncertain. To better understand this pathophysiological process, we used YO-PRO-1 uptake, dichlorofluorescein fluorescence, perforated-patch recordings, fura-2 imaging and trypan blue dye exclusion to assess the effects of the P2X7 agonist, benzoylbenzoyl-ATP (BzATP), on pore formation, oxidant production, ion channel activation, [Ca2+ ]i and cell viability...
September 2018: Vision
S Kauppinen, S S Karhula, J Thevenot, T Ylitalo, L Rieppo, I Kestilä, M Haapea, I Hadjab, M A Finnilä, E Quenneville, M Garon, H K Gahunia, K P H Pritzker, M D Buschmann, S Saarakkala, H J Nieminen
OBJECTIVE: Our aim is to establish methods for quantifying morphometric properties of calcified cartilage (CC) from micro-computed tomography (μCT). Furthermore, we evaluated the feasibility of these methods in investigating relationships between osteoarthritis (OA), tidemark surface morphology and open subchondral channels (OSCCs). METHOD: Samples (n = 15) used in this study were harvested from human lateral tibial plateau (n = 8). Conventional roughness and parameters assessing local 3-dimensional (3D) surface variations were used to quantify the surface morphology of the CC...
October 1, 2018: Osteoarthritis and Cartilage
Konstantinos Ekmektzoglou, Efstathios Nikou, Periklis Apostolopoulos, Despina Grigoraki, Konstantinos Manesis, Georgios Alexandrakis
Duodenal perforations due to biliary stenting migration, although rare, can occur. We report a unique case of duodenal perforation due to a large in length plastic stent with no (or marginal) migration, which ended up in the root of the mesentery, explaining the normal laboratory values and minimal imaging findings observed. Any clinical symptom during the postprocedural period should raise the suspicion of a major complication and prompt quick management decisions.
October 3, 2018: Clinical Journal of Gastroenterology
Mohannad Essam Elgamal, Essam A Elgamal, Anwar Ahmad, Adham Aly Elsayed, Basel Younes, Mohammad Khalid Aljaraki, Tamer Ibrahim Elholiby
Although ventriculoperitoneal shunt (VPS) is the most common procedure performed by pediatric neurosurgeons, it is still associated with frustrating complications, most common of which are obstruction and infection. Traumatic occipital artery pseudoaneurysm is a very rare complication of VPS procedure. To the best of our knowledge, there is no similar case reported in the English language literature. A 12-month-old patient suffered posthemorrhagic hydrocephalus of prematurity, and multiple other complications due to extreme prematurity, including immature lung disease, retinopathy of prematurity, necrotizing enterocolitis, bowel perforation, short bowel syndrome resulting in total parenteral nutrition-dependence, and hydrocephalus which was treated by insertion of VPS...
July 2018: Asian Journal of Neurosurgery
Hidetoshi Matsukawa, Hiroyasu Kamiyama, Takanori Miyazaki, Yu Kinoshita, Nakao Ota, Kosumo Noda, Norihiro Saito, Takaharu Shonai, Osamu Takahashi, Sadahisa Tokuda, Rokuya Tanikawa
The risk associated with surgical treatment for small-to-moderate size unruptured intracranial aneurysms (SMUIAs, defined as <15 mm) has not been well characterized. Authors aimed to investigate risk factors for poor outcome in surgical treatment of SMUIAs. The data of prospectively collected 801 consecutive patients harboring 971 surgically treated SMUIAs was evaluated. Neurological worsening (NW) was defined as an increase in 1 or more modified Rankin Scale at 12-month. Clinical and radiological characteristics were compared...
September 29, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
Zhongjie Wang, Xiaoping Yi, Jiqiang He, Liming Qing, Zhengbing Zhou, Youming Zhang, Zhiming Zhu, Chunhui Zhou, Hui Xie, Xuejun Li, Chishing Zee, Bihong T Chen
BACKGROUND:  During reconstructive surgery, anterolateral thigh (ALT) flap harvest is challenging due to variation and uncertainty in perforator distribution. We performed a pilot study to identify the predictive value of catheter-based computed tomography angiography (C-CTA) and traditional CTA (T-CTA) in ALT perforator mapping for patients whose ALT perforators were difficult to identify. METHODS:  Thirty-four consecutive T-CTA/C-CTA-mapped ALT flaps were evaluated for extremity reconstruction...
October 2, 2018: Journal of Reconstructive Microsurgery
Yue Cai, Ru Deng, Huabin Hu, Jianwei Zhang, Jiayu Ling, Zehua Wu, Liu Yang, Jianxia Li, Yanhong Deng
OBJECTIVE: To evaluate the safety and preliminary efficacy of dose-modified regimen of 5-fluorouracil plus oxaliplatin and irinotecan (mFOLFOXIRI) for patients with advanced colorectal cancer (CRC). METHODS: Data of 312 CRC patients confirmed by pathology receiving triplet drug alone or combined with target therapy between October 2012 and December 2016 at the Sixth Affiliated Hospital of Sun Yat-sen University were retrospectively analyzed. CRC patients who had previously completed adjuvant therapy (or neoadjuvant therapy) within 6 months or palliative chemotherapy were excluded, meanwhile those with poor general condition (ECOG score > 2) or grade 2 neuropathy and allergy to oxaliplatin were excluded as well...
September 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Yangyang Ji, Tao Peng, Guoqiang Wang, Yu Zhang, Mingfu Cao, Qiang Gao, Shuguang Li
OBJECTIVE: To evaluate the short-term efficacy and safety of neoadjuvant synchronous chemoradiotherapy (paclitaxel plus carboplatin regimen) in stage III adenocarcinoma of esophagogastric junction (AEG). METHODS: Forty cases clinically diagnosed as stage III AEG were prospectively enrolled at the Department of Gastrointestinal Oncology Surgery, the First Affiliated Hospital of Hebei North University from December 2014 to November 2017 and then were randomly divided into paclitaxel plus carboplatin combined with synchronous radiotherapy group(neoadjuvant group) and direct operation group...
September 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
Brendan M Case, Kyle K Jensen, Gene Bakis, Brintha K Enestvedt, Akram M Shaaban, Bryan R Foster
Endoscopic interventions play an important role in the modern management of pancreatic fluid collections. Successful management of pancreatitis is dependent on proper classification of the disease and its local complications. The 2012 revised Atlanta classification divides acute pancreatitis into subtypes of necrotizing pancreatitis and interstitial edematous pancreatitis (IEP) on the basis of the radiologic presence or absence of necrosis, respectively. Local complications of IEP include acute pancreatic fluid collections and pseudocysts, which contain fluid only and are differentiated by the time elapsed since the onset of symptoms...
September 28, 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
M Barone, A Cogliandro, E Tsangaris, R Salzillo, M Morelli Coppola, S Ciarrocchi, B Brunetti, S Tenna, V Tambone, P Persichetti
INTRODUCTION: The objectives of this study are: (1) comparison of long-term outcomes after correction of severe gynecomastia using different techniques; (2) apply the Italian version of the BODY-Q; (3) present the role of intercostal perforator flap (ICAP) after massive weight loss for correction of severe gynecomastia. MATERIALS AND METHODS: Between January 2008 and March 2016, we performed surgical correction of bilateral severe gynecomastia in 80 men (160 breasts) following massive weight loss...
September 26, 2018: Aesthetic Plastic Surgery
Brenton Keller, Mark Draelos, Gao Tang, Sina Farsiu, Anthony N Kuo, Kris Hauser, Joseph A Izatt
Ophthalmic procedures demand precise surgical instrument control in depth, yet standard operating microscopes supply limited depth perception. Current commercial microscope-integrated optical coherence tomography partially meets this need with manually-positioned cross-sectional images that offer qualitative estimates of depth. In this work, we present methods for automatic quantitative depth measurement using real-time, two-surface corneal segmentation and needle tracking in OCT volumes. We then demonstrate these methods for guidance of ex vivo deep anterior lamellar keratoplasty (DALK) needle insertions...
June 1, 2018: Biomedical Optics Express
Keiya Iijima, Yuki Tajika, Yukitaka Tanaka, Hiroshi Yorifuji, Yuhei Yoshimoto
BACKGROUND: Microvascular decompression for hemifacial spasm is performed at the root exit zone. More proximal segments of the facial nerve, defined as the root emerging zone (REmZ), may also be susceptible to neurovascular compression. Consequently, detailed knowledge of the microanatomy around facial nerve fibers at the pontomedullary junction is essential for consistent success of microvascular decompression. METHODS: Five human brainstems obtained from cadavers were investigated using correlative light microscopy and block-face imaging, which obtains arbitrary two-dimensional light microscopic and three-dimensional volume data from a single specimen...
October 2018: World Neurosurgery
Robert C Rennert, Ben A Strickland, Kristine Ravina, Joshua Bakhsheshian, Joseph Carey, Jonathan J Russin
BACKGROUND: Minimally invasive skull base approaches, including the cosmetically optimal transblepharo-preseptal modified orbitozygomatic (TBMOZ) technique, have been described to treat proximal anterior circulation aneurysms. The use of minimally invasive techniques for previously ruptured aneurysms is rare because of perceived technical challenges in controlling intraoperative ruptures. Herein, we determine the utility of the minimally invasive TBMOZ approach for the treatment of ruptured proximal anterior circulation aneurysms...
October 2018: World Neurosurgery
Mohamed Alaraby, Alba Hernández, Ricard Marcos
High aspect ratio nanomaterials (NM) have a promising future in medicine and industry as a unique category of NM. Consequently, it is important to evaluate their potential biological side-effects before crediting their use. To understand the mechanisms of degradation, internalisation, and interaction with different biological targets, we used the in vivo model Drosophila melanogaster to obtain a systematic and complete study on high aspect ratio Ni nanowires (NiNW), compared with low aspect ratio Ni nanospheres (NiNS), and NiSO4 as a model of agent releasing nickel ions...
September 25, 2018: Nanotoxicology
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