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Lei Zhu, Lun Dong, Yuping Li, Hengzhu Zhang, Xingdong Wang, Xiaoguang Liu, Zhenfei Teng, Boming Xia, Peng Zhang
OBJECTIVE: To evaluate the values of CSF and serum PCT for the diagnosis of intracranial infection after craniotomy and the relationship between them, and explore the PCT value about the application in the clinical antibiotics guidance. METHODS: Reviewing the incidence of intracranial infection in 21 craniotomy patients from the Subei People Hospital of Northern Jiangsu Province. CSF samples and venous blood were collected for the analysis. Diagnostic parameters were calculated via the ROC curves, and inflammatory indicators were analyzed before and after the application of antibiotics in the infection group...
December 11, 2018: World Neurosurgery
H L Haro-Gómez, E Merida-Herrera, B J Torres-Fernández, E Pérez-Hernández, R Torres-González, J M Pérez-Atanasio
BACKGROUND: Rheumatoid arthritis is a chronic inflammatory disease characterized by polyarthritis with progressive articular wear, immunologic abnormalities and increasing physical limitation. Surgical correction with hip replacement comes as a successful solution for patients with advanced articular destruction. Following intervention, surgical site infection (SSI), venous thromboembolism, sepsis, renal and major cardiovascular complications are among the most cited in the literature...
July 2018: Acta Ortopédica Mexicana
Guofeng Gao, Yanyan Zhao, Dong Zhang, Yuan He, Chenxi Song, Chenggang Zhu, Changdong Guan, Bo Xu, Dong Yin, Kefei Dou
OBJECTIVES: This study aimed to assess the risk stratification value of the SYNTAX Score II (SS II) in consecutive PCI patients and to analyze whether the predictive ability of SS II was consistent in patients with complex and non-complex coronary artery disease. BACKGROUND: SS II was designed for patients with complex coronary artery disease and has been validated by a number of studies in such patients. METHODS: The SS II for PCI was assessed in 10,072 consecutive patients who underwent PCI in Fuwai Hospital from January to December 2013...
December 14, 2018: Catheterization and Cardiovascular Interventions
Ariel Finkelstein, Zach Rozenbaum, Sophia Zhitomirsky, Amir Halkin, Shmuel Banai, Samuel Bazan, Israel Barbash, Amit Segev, Victor Guetta, Haim Danenberg, David Planner, Katia Orvin, Hana Vaknin Assa, Abid Assali, Ran Kornowski, Arie Steinvil
OBJECTIVE: To compare procedural outcomes of transcatheter aortic valve implantation (TAVI) patients who were implanted with older versus newer generation valves. BACKGROUND: The current evidence base for improved safety of the newer commercially available TAVI valves is limited. METHODS: A retrospective analysis of the Israeli multicenter TAVI registry was performed. Patients were stratified by valve generation of four commercially available devices: Edwards Sapien (ESX) Edwards Sapien S3 (ES3), Medtronic CoreValve (MCV), and Medtronic Evolut R (MER)...
December 13, 2018: Catheterization and Cardiovascular Interventions
Masami Yamamoto, Rodrigo Latorre, Juan Rojas, Bernardita Walker, Felipe Jordán, Jorge Carrillo, Enrique Paiva, Alvaro Insunza
AIM: Cesarean section rates are increasing worldwide and Robson's classification system allows a practical approach to study this phenomenon. C-section in Chile has been indicated as unexpectedly high, with important variability within the country and payment systems. The aim was to report our data using Robson's system and the evolution of local C-section rate in a public hospital during a 9-year period. METHODS: Retrospective analysis (2005-April 2014), in a metropolitan hospital in Santiago...
December 13, 2018: Journal of Obstetrics and Gynaecology Research
Najia Shahid, Ayesha Iqbal, Amna Jabbar Siddiqui, Muhammad Shoaib, Syed Ghulam Musharraf
BACKGROUND: Cancer of oral cavity is a seriously growing problem in many parts of the world. In Indian subcontinent, most of these cases have been attributed to the use of tobacco-related products. This study is focused on the identification of distinguishing metabolites of oral cancer in comparison with tobacco snuff dippers and healthy controls. METHODS: A total of 234 plasma samples including 62 healthy controls, 81 tobacco snuff dippers, and 91 oral cancer samples were analyzed using mass spectrometry...
December 13, 2018: Head & Neck
Amanual Getnet Mersha
BACKGROUND: One of the essential components of antenatal care (ANC) is birth preparedness and complication readiness (BP/CR). Strengthening BP/CR measures is one of the principal strategies to reduce maternal mortality and morbidity. The current study aimed at determining the level of men's knowledge about obstetric danger signs, and their involvement in BP/CR among community of Northwest Ethiopia. METHOD: A cross-sectional community based survey was conducted in Northwest Ethiopia from May 2016 to July 2016...
December 14, 2018: BMC Pregnancy and Childbirth
Diana Domanska, Chakravarthi Kanduri, Boris Simovski, Geir Kjetil Sandve
BACKGROUND: The current versions of reference genome assemblies still contain gaps represented by stretches of Ns. Since high throughput sequencing reads cannot be mapped to those gap regions, the regions are depleted of experimental data. Moreover, several technology platforms assay a targeted portion of the genomic sequence, meaning that regions from the unassayed portion of the genomic sequence cannot be detected in those experiments. We here refer to all such regions as inaccessible regions, and hypothesize that ignoring these regions in the null model may increase false findings in statistical testing of colocalization of genomic features...
December 14, 2018: BMC Bioinformatics
Emma Thomas, Mojtaba Lotfaliany, Sherry L Grace, Brian Oldenburg, C Barr Taylor, David L Hare, Wp Thanuja Rangani, Ds Anoja F Dheerasinghe, Dominique A Cadilhac, Adrienne O'Neil
BACKGROUND: Ageing populations and increasing survival following acute coronary syndrome has resulted in large numbers of people living with cardiovascular disease and at high risk of hospitalizations. Rising hospital admissions have a significant financial cost to the healthcare system. AIM: The purpose of this study was to determine whether cardiac rehabilitation is protective against long-term hospital readmission (frequency and length) following acute coronary syndrome...
December 14, 2018: European Journal of Cardiovascular Nursing
A Gilmartin, M Ryan
Aim To evaluate thyroid nodules and to determine the incidence of thyroid cancer. Methods This retrospective cohort study collected data from ten patients who presented with thyroid nodules to Barrington’s Hospital Limerick. Ultrasound/FNA results of thyroid nodules were used to measure the incidence of thyroid cancer. Results The number of thyroid nodules diagnosed as malignant was significantly greater than benign nodules (***p-value <0.0004, 95% confidence interval (-1.109 to -0.399)). This data indicates that females are more likely to develop thyroid cancer than males...
September 10, 2018: Irish Medical Journal
Sardar H Ijaz, Shakeel M Jamal, Rehan Qayyum
Background The hormones of the hypophysis-thyroid axis (HTA), thyroid stimulating hormone (TSH), and thyroid hormones, L-thyroxine (T4) and 3, 3', 5-L-triiodothyronine (T3), modulate the metabolism, differentiation, and proliferation of almost every cell in the body. Several studies have examined the effect of HTA hormones on platelet count and mean platelet volume (MPV), but have reported inconsistent results. Our aim was to examine the association between HTA hormones and platelet count and MPV in a large cohort of the adult population of the United States...
October 8, 2018: Curēus
Woineshet Asrat, Teferi Mekonnen, Melkamu Bedimo
Background: Ethiopia is a Sub Saharan African country with an estimated contraceptive prevalence rate of 36% and 22% unmet need for family planning service among married women. Client satisfaction influences the use of Family Planning and other reproductive health services. There is limited information on satisfaction with family planning service among Family planning users particularly in the northern part of Ethiopia. Hence, this study aimed to provide information on client satisfaction and its determinant among women in Public Health facilities of Northwestern Ethiopia...
2018: Contraception and Reproductive Medicine
Tricia Adjei, Jingwen Xue, Danilo P Mandic
Sex differences in the study of the human physiological response to mental stress are often erroneously ignored. To this end, we set out to show that our understanding of the stress response is fundamentally altered once sex differences are taken into account. This is achieved by comparing the heart rate variability (HRV) signals acquired during mental maths tests from ten females and ten males of similar maths ability; all females were in the follicular phase of their menstrual cycle. For rigor, the HRV signals from this pilot study were analyzed using temporal, spectral and nonlinear signal processing techniques, which all revealed significant statistical differences between the sexes, with the stress-induced increases in the heart rates from the males being significantly larger than those from the females ( p -value = 4...
2018: Frontiers in Physiology
N Santhoshi Revathy, R Kannan, R S Karthik, M S Senthil Kumar, M A I Munshi, R Vijay
Aim: This study was to evaluate and compare the bone regeneration potential of autologous platelet-rich fibrin (PRF) placed in one of the extracted sockets after the surgical removal of bilateral impacted mandibular third molars. Patients and Methods: Twenty-five patients (10 females and 15 males; 18-35 years old) were taken for surgical removal of bilateral impacted mandibular third molar, performed in the same session. The autologous PRF was placed in one of the extracted sockets whereas the opposite side was taken as control side, and primary closure was done...
July 2018: National Journal of Maxillofacial Surgery
Hai Deng, Pi Guo, Murui Zheng, Jun Huang, Yumei Xue, Xianzhang Zhan, Feng Wang, Yang Liu, Xianhong Fang, Hongtao Liao, Wei Wei, Yuanhong Liang, Fangzhou Liu, Zili Liao, Yijing Feng, Shulin Wu
Precise prevalence of atrial fibrillation (AF) and the associated risk factors in southern China are rarely reported. This large population-based follow-up study, the Guangzhou Heart Study, was conducted from 2015 to 2017 to fill up this gap. Permanent residents aged 35 years and above in Guangzhou city were enrolled and demographic factors of participants were collected by a structured questionnaire. Examinations of physical, electrocardiographic and biochemical indicators were performed following a standard operation procedure designed prior to the field investigation...
December 13, 2018: Scientific Reports
Michael J Burke, Wanda L Salzer, Meenakshi Devidas, Yunfeng Dai, Lia Gore, Joanne M Hilden, Eric Larsen, Karen R Rabin, Patrick A Zweidler-McKay, Michael J Borowitz, Brent Wood, Nyla A Heerema, Andrew J Carroll, Naomi Winick, William L Carroll, Elizabeth A Raetz, Mignon L Loh, Stephen P Hunger
With modern chemotherapy, approximately 90% of patients with pediatric acute lymphoblastic leukemia are now cured. However, subsets of patients can be identified who remain at very high risk of relapse with expected 4-year disease-free survival <80% and are appropriate candidates for intensive therapeutic strategies designed to improve survival. AALL1131 aimed to determine, in a randomized fashion, if the substitution with cyclophosphamide/etoposide (Experimental Arm 1) would improve the 4-year disease-free survival of children, adolescents, and young adults with very high-risk B-cell acute lymphoblastic leukemia compared to a modified Berlin-Frankfurt-Munster regimen (Control Arm)...
December 13, 2018: Haematologica
D Singla, A Parashar, V Pandey, M Mangla
OBJECTIVE: Various pharmacological agents have been tried to attenuate the pressor response in laparoscopic cholecystectomy patients. We have compared single pre-induction intravenous injection of dexmedetomidine with labetalol for attenuation of haemodynamic stress response. METHODS: A total of 160 patients were considered for this prospective, randomized, double blind clinical study done in a single tertiary care institution. Patients were either included in group D, to receive 1...
December 10, 2018: Revista Española de Anestesiología y Reanimación
J Król, U Nawrot, M Bartoszewicz
BACKGROUND: The presence of intron 25S allows to divide the Candida albicans species into three subclasses (A, B, C). Intronless and intron harboring strains were reported to have different susceptibility to some drugs, for example to flucytosine and bleomycin. OBJECTIVES: In this paper we tested the activity of selected antineoplastic agents, bleomycin, mitomycin C, dactinomycin and fluorouracil as well as antifungal drug flucytosine against 49 C. albicans isolates...
December 10, 2018: Journal de Mycologie Médicale
Nima Eftekhary, James E Feng, Afshin A Anoushiravani, Ran Schwarzkopf, Jonathan M Vigdorchik, William J Long
BACKGROUND: The Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) score is a nationally standardized measure of a patient's inpatient experience. This study aims to assess whether HCAHPS scores differ between patients undergoing primary total joint arthroplasty (TJA) and patients undergoing revision TJA. METHODS: Patients who underwent primary or revision total hip or total knee arthroplasty (THA or TKA) and returned a completed HCAHPS survey were included in this study...
November 20, 2018: Journal of Arthroplasty
Teerayut Temtanakitpaisan, Kai-Yun Wu, Chen-Ying Huang, Amruta Jaiswal, Chih-Feng Yen, Chyi-Long Lee
OBJECTIVES: Natural orifice transluminal endoscopic surgery (NOTES) is an emerging technique in the area of minimally invasive procedures. Preliminary reports have confirmed transvaginal NOTES to be a safe and feasible method for performing hysterectomy and adnexal procedures. However, there are limitations regarding the feasibility of performing transvaginal NOTES hysterectomy in various uterine sizes. MATERIALS AND METHODS: Two hundred and seventy-five women who had undergone transvaginal NOTES hysterectomy for benign pelvic lesions were recruited from May 2012 to May 2016...
December 2018: Taiwanese Journal of Obstetrics & Gynecology
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