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Ophthalmology. Glaucoma

Parampal S Grewal, Faraz Oloumi, Uriel Rubin, Matthew T S Tennant
Deep learning is an emerging technology with numerous potential applications in Ophthalmology. Deep learning tools have been applied to different diagnostic modalities including digital photographs, optical coherence tomography, and visual fields. These tools have demonstrated utility in assessment of various disease processes including cataracts, glaucoma, age-related macular degeneration, and diabetic retinopathy. Deep learning techniques are evolving rapidly, and will become more integrated into ophthalmic care...
August 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Jae Keun Chung, Jae Min Wi, Kwan Bok Lee, Byung Heon Ahn, Young Hoon Hwang, Mijin Kim, Jong Jin Jung, Young Cheol Yoo
PURPOSE: To compare long-term postoperative refractive outcomes between phacotrabeculectomy and phacoemulsification, both with posterior chamber intraocular lens implantation. SETTING: Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Seoul, South Korea. DESIGN: Retrospective comparative study. METHODS: Postoperative refractive outcomes were compared between patients with cataract and coexisting primary or secondary open-angle glaucoma (OAG) who had phacotrabeculectomy (combined group) and patients with cataract with or without coexisting OAG who had phacoemulsification alone (phaco-only group)...
August 2018: Journal of Cataract and Refractive Surgery
Dania A Bukhari, Sarah K Alessa, Safaa I Beheiri
Background: 5-Fluorouracil (5-FU) is a pyrimidine analogue which selectively inhibits DNA synthesis, RNA synthesis, and VEGF antibodies. 5-FU is widely used in ophthalmology for inhibition of postoperative corneal scarring and scleral bleb fibrosis. Case Presentation: In this case report, we describe an unusual case of a 65-year-old male who presented to the clinic with progressive decrease of vision after he underwent a revision of scleral bleb with the administration of 0...
January 2018: Case Reports in Ophthalmology
Rohit C Khanna, Gudlavalleti V S Murthy, Pyda Giridhar, Srinivas Marmamula, Hira B Pant, Ghanshyam Palamaner Subash Shantha, Subhabrata Chakrabarti, Clare E Gilbert, Gullapalli Nageswara Rao
AIM: To evaluate glaucoma-associated mortality in a rural cohort in India. METHODS: The study cohort comprised individuals aged 40 years and above who took part in the Andhra Pradesh Eye Disease Study (APEDS1) during 1996-2000. All participants underwent detailed comprehensive eye examination. Glaucoma was defined using International Society of Geographic and Epidemiologic Ophthalmology criteria. This cohort was followed up after a decade (June 2009 to January 2010; APEDS2)...
August 12, 2018: British Journal of Ophthalmology
Jost B Jonas, Wen Bin Wei, Liang Xu, Marcella Rietschel, Fabian Streit, Ya Xing Wang
PURPOSE: To assess the prevalence of depression in the general population of Beijing and its association with ocular diseases. METHODS: The population-based Beijing Eye Study was conducted in a rural and an urban region of Greater Beijing. The study participants underwent a detailed ophthalmological examination and an interview including questions on the socioeconomic background. Depressive symptoms were evaluated using a Chinese depression scale adapted from Zung´s self-rated depression scale...
2018: PloS One
Avrey Thau, Maureen Lloyd, Sharon Freedman, Allen Beck, Alana Grajewski, Alex V Levin
PURPOSE OF REVIEW: The Childhood Glaucoma Research Network (CGRN) has created a new classification system for childhood glaucoma that has become the first International Consensus Classification. The purpose of this review is to present this classification system and share its use to date. RECENT FINDINGS: The diagnoses of the classification system include glaucoma and glaucoma suspect. The primary glaucomas include: primary congenital glaucoma and juvenile open-angle glaucoma...
September 2018: Current Opinion in Ophthalmology
Rosanna Dammacco, Pasquale Procaccio, Vito Racanelli, Angelo Vacca, Franco Dammacco
PURPOSE: To assess the prevalence of the ocular manifestations related to the disease and/or ascribable to the administration of potentially toxic drugs in a cohort of 98 patients with systemic lupus erythematosus (SLE). METHODS: Retrospective, observational study reporting the experience of two tertiary referral centers. RESULTS: Overall, an ocular involvement was detected in 29 patients (29.6%), sometimes preceding of months the diagnosis of SLE, more often revealed at diagnosis or throughout its course...
August 10, 2018: Ocular Immunology and Inflammation
Cristobal Loezar, Eva Madrid, Catalina Jahr, Antonio Daviu, Herman Ahumada, Hector Pardo-Hernandez, Eva Keller, Xavier Bonfill
PURPOSE: Properly conducted controlled clinical trials (CCTs) provide the highest level of evidence for optimising decision-making in healthcare. Electronic search strategies do not exhaustively retrieve them, because of issues related to indexing, exclusion of journals in languages other than English, among others. A handsearch approach is therefore warranted. We aimed to identify all CCTs published in Ophthalmology journals in Spain, to describe their main features, and to submit them to the Cochrane Register of CCTs (CENTRAL)...
August 6, 2018: Ophthalmic Epidemiology
Kuryati Kipli, Mohammed Enamul Hoque, Lik Thai Lim, Muhammad Hamdi Mahmood, Siti Kudnie Sahari, Rohana Sapawi, Nordiana Rajaee, Annie Joseph
Digital image processing is one of the most widely used computer vision technologies in biomedical engineering. In the present modern ophthalmological practice, biomarkers analysis through digital fundus image processing analysis greatly contributes to vision science. This further facilitates developments in medical imaging, enabling this robust technology to attain extensive scopes in biomedical engineering platform. Various diagnostic techniques are used to analyze retinal microvasculature image to enable geometric features measurements such as vessel tortuosity, branching angles, branching coefficient, vessel diameter, and fractal dimension...
2018: Computational and Mathematical Methods in Medicine
Kyoung-Nam Kim, Il-Hwan Shin, Baek-Soo Kwak, Jae-Yun Sung, Hyung-Bin Lim, Young-Joon Jo, Jung-Yeul Kim
SIGNIFICANCE: Our authors studied the effects of measurement center shift on ganglion cell-inner plexiform layer (GCIPL) thickness measurements in Cirrus spectral-domain optical coherence tomography (SD-OCT). The measurement center shift affects the GCIPL thickness measurement depending on the distance of shift. PURPOSE: The purpose of this study was to explore changes in macular GCIPL thicknesses measurements after manual shifting of the measurement center using SD-OCT...
August 2018: Optometry and Vision Science: Official Publication of the American Academy of Optometry
Robert S Ackerman, Jonathan B Cohen, Rosemarie E Garcia Getting, Sephalie Y Patel
With the increasing popularity, frequency, and acceptance of the robotic-assisted laparoscopic radical prostatectomy procedure, an awareness of unique intra- and postoperative complications is heightened, including that of increases in intraocular pressure. The steep Trendelenburg positioning required for operative exposure has been shown to increase this value. While the literature is infrequent and undeveloped, certain anesthetic parameters including deep neuromuscular blockade, modified positioning, and the use of dexmedetomidine have been shown to have mild-to-modest decreases in intraocular pressure for baseline...
July 25, 2018: Journal of Robotic Surgery
Dan Călugăru, Mihai Călugăru, Ştefan Ţălu
AIM: To prospectively evaluate the cumulative prevalence and the management of ocular hypertension (OH) in patients with unilateral acute central/hemicentral retinal vein occlusions (C/HCRVOs) over the course of 3y. METHODS: The study included 57 patients with unilateral acute C/HCRVOs. All patients underwent a comprehensive ophthalmological examination of both eyes. OH associated with C/HCRVO in patients showing a score >5% for the risk of conversion to primary open angle glaucoma (POAG) was treated with OH medication...
2018: International Journal of Ophthalmology
Isabelle Francisca Petronella Maria Kappen, Duy Thuan Nguyen, Albert Vos, Hermanus Wilhelmus Hendricus Joseph van Tits
Blepharoplasty is one of the most commonly performed aesthetic procedures. Surgical complications are rare, but can have severe consequences, such as permanent vision loss. In this report, we describe a patient who developed primary angle-closure glaucoma (ACG) with associated vision loss after a oculoplastic procedure using local anesthesia. So far, six similar cases have been described in the literature. It is believed that acute ACG is triggered by the surgical procedure in patients with predisposing risk factors such as a cataract...
July 2018: Archives of Plastic Surgery
Yong Un Shin, Eun Hee Hong, Min Ho Kang, Heeyoon Cho, Mincheol Seong
Purpose: We investigated associations between female reproductive factors and open-angle glaucoma (OAG) in Korean females using the Korea National Health and Nutrition Examination Survey (KNHANES). Methods: A nationwide, population-based, cross-sectional study was conducted. We enrolled 23,376 participants from the KNHANES who had undergone ophthalmologic exams from 2010 through 2012. Associations between undiagnosed OAG and female reproductive factors such as age at menarche and menopause, parity, history of lactation, and administration of oral contraceptives (OC) or hormone replacement therapy (HRT) were determined using stepwise logistic regression analyses...
2018: Journal of Ophthalmology
José Luis Treviño González, German A Soto-Galindo, Rafael Moreno Sales, Josefina A Morales Del Ángel
The Cogan's syndrome (CS) is a very uncommon inflammatory condition that appears in young adults without a gender predisposition. It can be presented as typical, with interstitial non-syphilitic keratitis and Ménière-like audiovestibular manifestations. An atypical form of CS involves uveitis, scleritis, episcleritis, and systemic vascuitis symptoms. This is a case of a 41-year old male who reported eye redness, photophobia, and gait instability. His condition progressed to a sudden sensorineural hearing loss, tinnitus, and constant vertigo accompanied by cephalea...
June 2018: Annals of Medicine and Surgery
Geetha Srinivasan, Gudlavalleti Venkata Satyanarayana Murthy, Shalini Mohan, Kalaivani Mani, Praveen Vashist, Nina John, Viney Gupta, Ramanjit Sihota
PURPOSE: To study optic nerve head (ONH) characteristics using scanning laser ophthalmoscopy, Heidelberg retina tomograph (HRT), in an elderly population. METHODS: A population-based, cross-sectional study included 1460 eyes of 1460 consecutive, subjects >60 years, in North India. All subjects underwent a detailed ophthalmic evaluation and imaged on HRT. Stereometric parameters, Moorfields regression analysis (MRA) and discriminant function analysis were analyzed...
July 17, 2018: Ophthalmic Epidemiology
McKayla J Riggs, Naikeya H Coston, Nicholas R Teneyuque, Erin A Keyser
Subconjunctival hemorrhages are common in trauma and with increased intra-abdominal pressure. Despite the sustained pressure endured while pushing, they are rarely observed postpartum and can be an indicator of underlying ophthalmic disease. We present a case of a postpartum patient who developed bilateral subconjunctival hemorrhages with a retro-orbital hematoma. The patient is a 29-year-old gravida-1-para-0 at 41 weeks gestation who underwent an uncomplicated induction and delivery. She developed diplopia and orbital pain postpartum...
July 12, 2018: Military Medicine
Yoon Pyo Lee, Young-Su Ju, Dong Gyu Choi
The purpose of this study was to identify the normative values of ganglion cell-inner plexiform layer (GCIPL) thickness in healthy Korean children using swept-source optical coherence tomography (SS-OCT) and to investigate the correlations of age, refractive error, axial length (AL), retinal nerve fiber layer (RNFL) thickness and cup-to-disc (C/D) ratio with GCIPL thickness. Children aged between 3 and 17 who had visited our pediatric ophthalmology clinic were enrolled. Each subject underwent full ophthalmic examinations including RNFL thickness, C/D ratio and GCIPL thickness measurement by SS-OCT as well as AL measurement by partial-coherence interferometry...
July 13, 2018: Scientific Reports
Matthew Yu Heng Wong, Nicholas Y Q Tan, Charumathi Sabanayagam
We analysed the 100 top cited articles in ophthalmology to identify and characterise the most influential articles of the past four decades. Two independent investigators searched the Scopus database to determine the 100 most frequently cited articles in ophthalmology (T100-Eye) and general non-ophthalmology journals (T100-Gen) published from 1975 to December 2017. The T100-Eye list consisted of 83 original articles and 17 reviews, and the number of citations ranged from 582 to 2833. Seventy-eight of these articles were published in three journals alone (impact factor (IF): 5...
July 12, 2018: British Journal of Ophthalmology
Nara Lidia V Lopes, Carolina P B Gracitelli, Christiane Rolim de Moura
PURPOSE: The aim is creation of a database to register patients diagnosed with childhood glaucoma. Information collection and storage will utilize a digital platform that permits multiple centers to register patients. This registry will be an important tool to evaluate and group patient profiles, thus allowing identification of risk factors, estimating prevalence, and recruiting participants in future studies. METHODS: An online form was designed at the Department of Ophthalmology and Visual Sciences of the Federal University of São Paulo to create a registry of patients diagnosed with congenital glaucoma...
July 2018: Arquivos Brasileiros de Oftalmologia
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