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Ophthalmology. Glaucoma

Teresa C Chen, Ambika Hoguet, Anna K Junk, Kouros Nouri-Mahdavi, Sunita Radhakrishnan, Hana L Takusagawa, Philip P Chen
PURPOSE: To review the current published literature on the use of spectral domain (SD) OCT to help detect changes associated with the diagnosis of glaucoma. METHODS: Searches of the peer-reviewed literature were conducted on June 11, 2014, November 7, 2016, August 8, 2017, and April 19, 2018, in the PubMed and Cochrane Library databases and included only articles published since the last glaucoma imaging Ophthalmic Technology Assessment, which included articles up until February 2006...
November 2018: Ophthalmology
Ayisha Kausar, Nadia Akhtar, Farooq Afzal, Khalid Ali
OBJECTIVE: To evaluate the effect of refractive error and axial length on peripapillary retinal nerve fibre layer thickness in myopic, hypermetropic and emmetropic eyes by Topcon spectral domain optical coherence tomography. METHODS: This cross-sectional study was conducted at the ophthalmology clinic of Shifa Foundation Falahee Clinic, Islamabad, Pakistan, from January to December 2016, and comprised eye patients including emmetropes, hypermetropes and myopes. All participants underwent detailed ophthalmic examination including axial lengths measurements, auto refraction andretinal nerve fibre layer thickness analysis...
July 2018: JPMA. the Journal of the Pakistan Medical Association
Jean-Claude Mwanza, Samantha E Tulenko, Keith Barton, Leon W Herndon, Elizabeth Mathenge, Alyson Hall, Hanna Y Kim, Graham Hay-Smith, Donald L Budenz
PURPOSE: To determine the incidence of open-angle glaucoma (OAG) and its risk factors in the Tema Eye Survey, a population-based eye survey in Ghana, West Africa. DESIGN: Longitudinal observational population-based study. PARTICIPANTS: One thousand two hundred and five out of 1500 subjects aged 40 years or older, randomly selected from 5603 subjects originally drawn from the population and who had undergone a baseline examination. METHOD: All participants underwent baseline and follow-up ophthalmologic examinations 8 years apart...
October 11, 2018: Ophthalmology
Stéphanie Romeo Villadóniga, Elena Rodríguez García, Olatz Sagastagoia Epelde, M Dolores Álvarez Díaz, Joan Carles Domingo Pedrol
Purpose: To assess the effects of antioxidant oral supplementation based on docosahexaenoic acid (DHA) in pseudoexfoliative (PEX) glaucoma. Patients and Methods: A prospective 6-month open-label randomized controlled trial was conducted in patients with PEX glaucoma and adequate intraocular pressure (IOP) control. Patients in the DHA group received a high-rich DHA (1 g) nutraceutical formulation. Ophthalmological examination, DHA erythrocyte membrane content (% total fatty acids), plasma total antioxidant capacity (TAC), plasma malondialdehyde (MDA), and plasma IL-6 levels were assessed...
2018: Journal of Ophthalmology
Jae Yeun Lee, Joon Mo Kim, Seong Ho Kim, In Tae Kim, Hyun Tae Kim, Pil-Wook Chung, Jeong Hun Bae, Yu Sam Won, Mi Yeon Lee, Ki Ho Park
PURPOSE: To investigate the association between factors associated with parturition and open-angle glaucoma (OAG) in Korean females. METHODS: A population-based, cross-sectional survey was performed from the Korean National Health and Nutrition Examination Survey from 2010-2011 and enrolled postmenopausal female participants (n=1798). We obtained information on demographics, comorbidities, and health-related behaviors and performed comprehensive ophthalmic examinations...
October 8, 2018: Journal of Glaucoma
Brendon Wong, Clare L Fraser
BACKGROUND: Obstructive sleep apnea (OSA) is a common pulmonary disorder with many systemic sequelae. Its association with diseases seen in neuro-ophthalmology is being increasingly recognized. Treatment of OSA with continuous positive airway pressure (CPAP) may reverse the pathology in some eye diseases. EVIDENCE ACQUISITION: We conducted a search of the literature using the Ovid Medline database and Google Scholar, focusing on articles that explored the association between OSA and ophthalmic conditions...
October 8, 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
Andreia Soares, Nuno Lopes, Gabriel Morgado, Josefina Serino, Teresa Painhas, Cristina Almeida, Fernando Vaz
PURPOSE: The aim of this study is to analyze the lamina cribrosa depth and to study the optic nerve in patients with spontaneous intracranial hypotension. METHODS: A total of 10 eyes of the patients with spontaneous intracranial hypotension with unknown etiology (study group) and 10 eyes of healthy patients without any ophthalmological or neurological pathologies (control group) were included. The subjects were submitted to ophthalmological examination with the evaluation of visual acuity, spherical equivalent, applanation tonometry, pachymetry, axial length, retinography, computerized static perimetry (Humphrey 30-2 SITA-Standard), and OCT Spectralis with enhanced depth image, to calculate the depth of the anterior surface of the lamina cribrosa and to measure the nerve fiber layer thickness of the optic nerve...
October 7, 2018: European Journal of Ophthalmology
Koen Willekens, Luìs Abegão Pinto, Sophie Lemmens, Sophie Bataillie, Alix Somers, Evelien Vandewalle, Peter Stalmans, Ingeborg Stalmans
PURPOSE: To investigate the vitreopapillary interface (VPI) in health and glaucoma according to the different stages of posterior vitreous detachment (PVD) formation. METHODS: Prospective single centre study including healthy subjects and glaucoma patients. PVD staging was performed with spectral domain optical coherence tomography. Gender, age, lens status and refractive error were assessed in both groups. Glaucoma patients additionally had a comprehensive ophthalmological investigation including intraocular pressure measurement, visual field testing and confocal imaging of the optic nerve head...
October 2, 2018: Acta Ophthalmologica
Naoto Shibata, Masaki Tanito, Keita Mitsuhashi, Yuri Fujino, Masato Matsuura, Hiroshi Murata, Ryo Asaoka
The Purpose of the study was to develop a deep residual learning algorithm to screen for glaucoma from fundus photography and measure its diagnostic performance compared to Residents in Ophthalmology. A training dataset consisted of 1,364 color fundus photographs with glaucomatous indications and 1,768 color fundus photographs without glaucomatous features. A testing dataset consisted of 60 eyes of 60 glaucoma patients and 50 eyes of 50 normal subjects. Using the training dataset, a deep learning algorithm known as Deep Residual Learning for Image Recognition (ResNet) was developed to discriminate glaucoma, and its diagnostic accuracy was validated in the testing dataset, using the area under the receiver operating characteristic curve (AROC)...
October 2, 2018: Scientific Reports
Maceda Gurabardhi, Heike Häberle, Henning Aurich, Liliana Werner, Duy-Thoai Pham
PURPOSE: To report clinical findings and light microscopic results of 71 opacified hydrophilic acrylic intraocular lenses (IOLs). SETTING: Vivantes Klinikum Neukoelln, Ophthalmology Department, Berlin, Germany. DESIGN: Retrospective case series. METHODS: Sixty-three patients (71 eyes) were referred to the clinic because of vision-impairing IOL opacification between December 2012 and September 2016 after routine cataract surgery elsewhere...
September 29, 2018: Journal of Cataract and Refractive Surgery
Haihan Jiao, Lisa J Hill, Laura E Downie, Holly R Chinnery
Optical coherence tomography (OCT) provides non-invasive, high-resolution in vivo imaging of the ocular surface and anterior segment. Over the years, it has become an essential tool for evaluating the anterior segment of the eye to monitor ocular development and ocular pathologies in both the clinical and research fields of ophthalmology and optometry. In this review, the clinical applications relating to the use of anterior segment OCT for imaging and quantifying normal and pathological features of the ocular surface, cornea, anterior chamber, and aqueous outflow system are summarised in a range of human ocular diseases...
October 1, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Chunlan Yang, Min Lu, Yanhua Duan, Bing Liu
BACKGROUND: Optic cup is an important structure in ophthalmologic diagnosis such as glaucoma. Automatic optic cup segmentation is also a key issue in computer aided diagnosis based on digital fundus image. However, current methods didn't effectively solve the problem of edge blurring caused by blood vessels around the optic cup. METHODS: In this study, an improved Bertalmio-Sapiro-Caselles-Ballester (BSCB) model was proposed to eliminate the noising induced by blood vessel...
September 26, 2018: Biomedical Engineering Online
Abdel-Razzak M Al-Hinnawi, Arqam M Alqasem, Bassam O Al-Naami
PURPOSE: To propose an innovative three-dimensional surface presentation of the optic nerve head (ONH) from the SPECTRALIS optical coherence tomography (OCT) device. METHOD: A dataset of OCT ONH files from eight glaucoma follow-up patients was obtained. The set consisted of OCT ONH images for 20 right eyes (OD) and 17 left eyes (OS). Preprocessing steps followed with OCT reconstruction procedures were designed. The three-dimensional (3D) surface rendering was generated for all OCT ONH images...
September 24, 2018: International Ophthalmology
Judith Ungewiss, Thomas Kübler, Katrin Sippel, Kathrin Aehling, Martin Heister, Wolfgang Rosenstiel, Enkelejda Kasneci, Eleni Papageorgiou
PURPOSE: On-road testing is considered the standard for assessment of driving performance; however, it lacks standardization. In contrast, driving simulators provide controlled experimental settings in a virtual reality environment. This study compares both testing conditions in patients with binocular visual field defects due to bilateral glaucomatous optic neuropathy or due to retro-chiasmal visual pathway lesions. METHODS: Ten glaucoma patients (PG), ten patients with homonymous visual field defects (PH), and 20 age- and gender-matched ophthalmologically normal control subjects (CG and CH, respectively) participated in a 40-min on-road driving task using a dual brake vehicle...
September 24, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Lidia Kun, Andrea Szigeti, Maria Bausz, Zoltan Zsolt Nagy, Erika Maka
PURPOSE: To investigate the differences in biometry data of eyes with unilateral congenital cataract and the contralateral normal eyes in pediatric patients. SETTING: Pediatric Ophthalmology Division, Ophthalmology Department, Semmelweis University in Budapest, Hungary. DESIGN: Retrospective case series. METHODS: Data of visually significant unilateral congenital cataract patients who had cataract surgery in the ophthalmology department at Semmelweis University between 2013 and 2016 were collected...
October 2018: Journal of Cataract and Refractive Surgery
Bekir Selim Bagli, Sadik Görkem Çevik, Mediha Tok Çevik
Background: Central retinal artery occlusion (CRAO) is a rare and serious ophthalmologic emergency with a bad prognosis. Hyperbaric oxygen (HBO2) treatment has been reported to improve visual acuity of CRAO patients. However, there are unknown variables for HBO2 treatment such as initiation period, number of sessions and efficacy. In this study, we aimed to investigate efficacy of HBO2 treatment in CRAO patients. Methods: Patients who had been diagnosed with CRAO and referred to our Hyperbaric Oxygen Treatment Unit with the indication of HBO2 treatment were included in the study...
July 2018: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
Akef El-Maghraby, Amin elMaghraby, Mutasim Alireza, Daniel E Etya'ale, William C Felch, Tamer Makary, Henry E Nkumbe, David E I Pyott, Serge Resnikoff, Alfred Sommer, Bruce E Spivey, Bradley R Straatsma, Hugh R Taylor
PURPOSE: To report establishment of the Magrabi ICO Cameroon Eye Institute at Yaoundé, Cameroon, as an ophthalmology subspecialty patient care and training center in Central Africa. DESIGN: Perspective METHODS: Assessment of unpublished and published material. RESULTS: To improve, preserve and restore eye health and vision in a region with world-high prevalence of functional vision impairment and blindness, the Africa Eye Foundation established the Magrabi ICO Cameroon Eye Institute as an ophthalmology subspecialty patient care center for all in need and a training center for ophthalmologists, ophthalmology subspecialists and allied personnel...
September 18, 2018: American Journal of Ophthalmology
Ke Xu, Lingling Wu, Zhizhong Ma, Yuling Liu, Fang Qian
PURPOSE: To investigate the frequency of primary angle closure (PAC) and primary angle closure glaucoma (PACG) in patients with retinal vein occlusion (RVO) based on a hospital population. METHODS: A total of 375 consecutive cases newly diagnosed with RVO by fluorescein fundus angiography at a single eye centre in Peking were reviewed. Gonioscopy was performed in all patients. Glaucoma was diagnosed according to the criteria of the International Society of Geographical and Epidemiological Ophthalmology...
September 21, 2018: Acta Ophthalmologica
Jordan Stanley, Carrie E Huisingh, Thomas A Swain, Gerald McGwin, Cynthia Owsley, Christopher A Girkin, Lindsay A Rhodes
PURPOSE: To determine the level of adherence to the American Academy of Ophthalmology (AAO) preferred practice pattern (PPP) guidelines for quality primary open angle glaucoma (POAG) and POAG suspect (POAGS) care among retail-based optometrists. METHODS: Patients with a diagnosis of POAG or POAGS who participated in a telemedicine pilot project were included. Patients' charts were evaluated for 15 elements of PPP guidelines for glaucoma care. Results were further stratified by number of follow-up visits and diagnosis...
September 18, 2018: Journal of Glaucoma
Xue-Li Du, Wen-Bo Li, Bo-Jie Hu
Artificial intelligence is a general term that means to accomplish a task mainly by a computer, with the least human beings participation, and it is widely accepted as the invention of robots. With the development of this new technology, artificial intelligence has been one of the most influential information technology revolutions. We searched these English-language studies relative to ophthalmology published on PubMed and Springer databases. The application of artificial intelligence in ophthalmology mainly concentrates on the diseases with a high incidence, such as diabetic retinopathy, age-related macular degeneration, glaucoma, retinopathy of prematurity, age-related or congenital cataract and few with retinal vein occlusion...
2018: International Journal of Ophthalmology
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