keyword
https://read.qxmd.com/read/38550667/obsessive-compulsive-disorder-a-medical-school-curriculum-and-textbook-review
#21
JOURNAL ARTICLE
Chelsea A Lahey, Emily J Fawcett, Noah Pevie, Rowan B Seim, Jonathan M Fawcett
OBJECTIVES: We conducted a curriculum review of Canadian undergraduate medical programs to identify why aggressive obsessions (among those with obsessive-compulsive disorder [OCD]) are so often misidentified by primary care physicians and professional students. METHODS: This study involved standardized interviews with representatives from Canadian medical schools regarding the content, time, and teaching styles used to deliver curricula related to OCD. Further, we utilized a set of standardized criteria to assess the OCD content of recommended textbooks from these schools...
2024: Journal of Medical Education and Curricular Development
https://read.qxmd.com/read/38538268/deciphering-a-prognostic-signature-based-on-soluble-mediators-defines-the-immune-landscape-and-predicts-prognosis-in-hnscc
#22
JOURNAL ARTICLE
Hao Chi, Gaoge Peng, Guobin Song, Jinhao Zhang, Xixi Xie, Jinyan Yang, Jiayu Xu, Jieying Zhang, Ke Xu, Qibiao Wu, Guanhu Yang
BACKGROUND: The study on Head and Neck Squamous Cell Carcinoma (HNSCC), a prevalent and aggressive form of head and neck cancer, focuses on the often-overlooked role of soluble mediators. The objective is to leverage a transcriptome-based risk analysis utilizing soluble mediator-related genes (SMRGs) to provide novel insights into prognosis and immunotherapy efficacy in HNSCC patients. METHODS: We analyzed the expression and prognostic significance of 10,859 SMRGs using 502 HNSCC and 44 normal samples from the TCGA-HNSC cohort in The Cancer Genome Atlas (TCGA)...
March 22, 2024: Frontiers in Bioscience (Landmark Edition)
https://read.qxmd.com/read/38537154/the-future-of-liver-transplantation
#23
JOURNAL ARTICLE
Sandy Feng, Garrett R Roll, Foad J Rouhani, Alberto Sanchez Fueyo
Over the last 50 years, liver transplantation has evolved into a procedure routinely performed in many countries worldwide. Those able to access this therapy frequently experience a miraculous risk-benefit ratio since, particularly if they face imminently life threatening disease. Over the decades, the success of liver transplantation, with dramatic improvements in early post-transplant survival, has aggressively driven demand. However, in spite of the emergence of living donors to augment deceased donors as a source of organs, supply has lagged far behind demand...
March 27, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://read.qxmd.com/read/38532533/using-delphi-method-to-address-factors-contributing-to-aggressive-behaviour-in-mental-health-settings
#24
JOURNAL ARTICLE
Rasha Eweida, Nashwa Ibrahim
WHAT IS KNOWN ABOUT THE SUBJECT?: Nurses' perspectives and consensus on the possible key factors contributing to aggression at inpatient units can be summarized into patients' related factors, staff related factors and environment related factors. Results of the possible factors contributing to aggression at inpatient units reflect the complicated nature of this problem. WHAT THE PAPER ADDS TO EXISTING KNOWLEDGE: Perspectives of nurses as frontline mental health professionals on factors contributing to aggression as one of the psychiatric emergencies were considered through an iterative process...
March 26, 2024: Journal of Psychiatric and Mental Health Nursing
https://read.qxmd.com/read/38528804/interplay-of-combat-deployment-harassment-testosterone-concentrations-and-post-deployment-suicide-risk-in-male-veterans
#25
JOURNAL ARTICLE
Leo Sher, Linda M Bierer, Janine Flory, Iouri Makotkine, Rachel Yehuda
OBJECTIVE: Many combat veterans exhibit suicidal ideation and behavior, but the relationships among experiences occurring during combat deployment and suicidality are still not fully understood. In this study, we tested the hypothesis that harassment during a combat deployment is associated with post-deployment suicidality and testosterone function. METHODS: Male combat veterans who made post-deployment suicide attempts and demographically matched veterans without a history of suicide attempts were enrolled in the study...
March 26, 2024: Acta Neuropsychiatrica
https://read.qxmd.com/read/38527044/interventions-to-address-mealtime-support-needs-in-dementia-a-scoping-review
#26
JOURNAL ARTICLE
Lígia Passos, João Tavares, Melissa Batchelor, Daniela Figueiredo
The decrease in cognitive and physical ability among people with dementia can significantly affect eating performance, resulting in mealtime support needs that could lead to inadequate oral intake, weight loss, malnutrition, and reduced functionality in activities of daily living. This scoping review aimed to identify and summarize available research literature on mealtime interventions for people with dementia, and their impact on older people with dementia living in a residential care setting, care staff, and care context/environment...
2024: PloS One
https://read.qxmd.com/read/38514412/perceptions-and-knowledge-of-undergraduate-dental-students-about-artificial-intelligence-in-dental-schools-a-cross-sectional-study
#27
JOURNAL ARTICLE
Omir Aldowah, Abdullah Almakrami, Yazeed Alghuwaynim, Mohammed Alhutaylah, Ali Almansour, Ali Alswedan, Falah Alshahrani, Saad Alqarni, Yahia Alkasi
OBJECTIVE: This study aims to assess the perceptions and knowledge of undergraduate dental students about artificial intelligence (AI) in dental schools through a cross-sectional study. MATERIALS AND METHODS: This was a multicenter, cross-sectional study. Participant recruitment was achieved by sending an online questionnaire to the undergraduate students at the assigned universities. The questionnaire consisted of two parts. The first seven questions record general information about participants and their perceptions of AI...
February 1, 2024: Journal of Contemporary Dental Practice
https://read.qxmd.com/read/38510670/transfer-learning-with-pretrained-convolutional-neural-network-for-automated-gleason-grading-of-prostate-cancer-tissue-microarrays
#28
JOURNAL ARTICLE
Parisa Gifani, Ahmad Shalbaf
BACKGROUND: The Gleason grading system has been the most effective prediction for prostate cancer patients. This grading system provides this possibility to assess prostate cancer's aggressiveness and then constitutes an important factor for stratification and therapeutic decisions. However, determining Gleason grade requires highly-trained pathologists and is time-consuming and tedious, and suffers from inter-pathologist variability. To remedy these limitations, this paper introduces an automatic methodology based on transfer learning with pretrained convolutional neural networks (CNNs) for automatic Gleason grading of prostate cancer tissue microarray (TMA)...
2024: Journal of Medical Signals and Sensors
https://read.qxmd.com/read/38509935/fear-of-violence-and-working-department-influences-physical-aggression-level-among-nurses-in-northwest-ethiopia-government-health-facilities
#29
JOURNAL ARTICLE
Dawit Getachew Yenealem, Avier Mesfin Mengistu
PURPOSE: Violence is recognized as an extreme expression of aggressive behavior and physical violence is most recognized type among victims. Patients always come to the hospitals looking for a cure, remedy, or assurance; however, incompatibility of demand and service often results in violent incidents that become statuesque in health facilities. This study aims to investigate physical violence and associated factors among nurses in health facilities in Gondar town, Ethiopia. METHOD: The study was an institutional-based cross-sectional study among nurses in Gondar town from April to May 2017...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38507859/an-analysis-of-the-effect-of-motor-experience-on-muscle-synergy-in-the-badminton-jump-smash
#30
JOURNAL ARTICLE
Zhengye Pan, Lushuai Liu, Xingman Li, Yunchao Ma
The jump smash is badminton's most aggressive technical manoeuvre, which is often the key to winning a match. This paper aims to explore the neuromuscular control strategies of advanced and beginner players when jumping smash in different ways. Collecting sEMG and kinematic data from 18 subjects with different motor experiences when jumping smash. Nonnegative Matrix Factorization and K-Means clustering were used to extract muscle synergies and exclude irrelevant combined synergies. Uncontrolled manifold analysis was then used to explore the association between synergies and shoulder stability...
March 19, 2024: Human Movement Science
https://read.qxmd.com/read/38504364/a-deep-learning-workflow-to-predict-upper-tract-urothelial-carcinoma-protein-based-subtypes-from-h-e-slides-supporting-the-prioritization-of-patients-for-molecular-testing
#31
JOURNAL ARTICLE
Miriam Angeloni, Thomas van Doeveren, Sebastian Lindner, Patrick Volland, Jorina Schmelmer, Sebastian Foersch, Christian Matek, Robert Stoehr, Carol I Geppert, Hendrik Heers, Sven Wach, Helge Taubert, Danijel Sikic, Bernd Wullich, Geert Jlh van Leenders, Vasily Zaburdaev, Markus Eckstein, Arndt Hartmann, Joost L Boormans, Fulvia Ferrazzi, Veronika Bahlinger
Upper tract urothelial carcinoma (UTUC) is a rare and aggressive, yet understudied, urothelial carcinoma (UC). The more frequent UC of the bladder comprises several molecular subtypes, associated with different targeted therapies and overlapping with protein-based subtypes. However, if and how these findings extend to UTUC remains unclear. Artificial intelligence-based approaches could help elucidate UTUC's biology and extend access to targeted treatments to a wider patient audience. Here, UTUC protein-based subtypes were identified, and a deep-learning (DL) workflow was developed to predict them directly from routine histopathological H&E slides...
March 2024: Journal of Pathology. Clinical Research
https://read.qxmd.com/read/38501040/socioeconomic-status-and-intimate-partner-aggression-a-serial-mediation-of-impulsivity-and-anger
#32
JOURNAL ARTICLE
Julia Friederike Hammett, Kelly Cue Davis
Understanding the mechanisms underlying the association between lower socioeconomic status (SES) and Intimate Partner Aggression (IPA) is necessary for decreasing risk for IPA among lower-SES individuals. As limited control over one's external environment impacts individuals' ability to internally control their emotional states, the present study examined impulsivity and anger as serial mediators in the association from SES to IPA perpetration. Structural equation modeling analyses ( N = 430 men, M age = 24...
November 2023: Current Psychology
https://read.qxmd.com/read/38493072/performance-of-a-region-of-interest-based-algorithm-in-diagnosing-international-society-of-urological-pathology-grade-group-%C3%A2-2-prostate-cancer-on-the-mri-first-database-cad-first-study
#33
JOURNAL ARTICLE
Thibaut Couchoux, Tristan Jaouen, Christelle Melodelima-Gonindard, Pierre Baseilhac, Arthur Branchu, Nicolas Arfi, Richard Aziza, Nicolas Barry Delongchamps, Franck Bladou, Flavie Bratan, Serge Brunelle, Pierre Colin, Jean-Michel Correas, François Cornud, Jean-Luc Descotes, Pascal Eschwege, Gaelle Fiard, Bénédicte Guillaume, Rémi Grange, Nicolas Grenier, Hervé Lang, Frédéric Lefèvre, Bernard Malavaud, Clément Marcelin, Paul C Moldovan, Nicolas Mottet, Pierre Mozer, Eric Potiron, Daniel Portalez, Philippe Puech, Raphaele Renard-Penna, Matthieu Roumiguié, Catherine Roy, Marc-Olivier Timsit, Thibault Tricard, Arnauld Villers, Jochen Walz, Sabine Debeer, Adeline Mansuy, Florence Mège-Lechevallier, Myriam Decaussin-Petrucci, Lionel Badet, Marc Colombel, Alain Ruffion, Sébastien Crouzet, Muriel Rabilloud, Rémi Souchon, Olivier Rouvière
BACKGROUND AND OBJECTIVE: Prostate multiparametric magnetic resonance imaging (MRI) shows high sensitivity for International Society of Urological Pathology grade group (GG) ≥2 cancers. Many artificial intelligence algorithms have shown promising results in diagnosing clinically significant prostate cancer on MRI. To assess a region-of-interest-based machine-learning algorithm aimed at characterising GG ≥2 prostate cancer on multiparametric MRI. METHODS: The lesions targeted at biopsy in the MRI-FIRST dataset were retrospectively delineated and assessed using a previously developed algorithm...
March 15, 2024: European Urology Oncology
https://read.qxmd.com/read/38492045/predicting-event-free-survival-after-induction-of-remission-in-high-risk-pediatric-neuroblastoma-combining-123-i-mibg-spect-ct-radiomics-and-clinical-factors
#34
JOURNAL ARTICLE
Lijuan Feng, Xu Yang, Chao Wang, Hui Zhang, Wei Wang, Jigang Yang
BACKGROUND: Accurately quantifying event-free survival after induction of remission in high-risk neuroblastoma can lead to better subsequent treatment decisions, including whether more aggressive therapy or milder treatment is needed to reduce unnecessary treatment side effects, thereby improving patient survival. OBJECTIVE: To develop and validate a 123 I-metaiodobenzylguanidine (MIBG) single-photon emission computed tomography-computed tomography (SPECT-CT)-based radiomics nomogram and evaluate its value in predicting event-free survival after induction of remission in high-risk neuroblastoma...
March 16, 2024: Pediatric Radiology
https://read.qxmd.com/read/38481457/barriers-experienced-by-nurses-in-communication-for-sexual-health-education-for-children-with-intellectual-disability-a-qualitative-study
#35
JOURNAL ARTICLE
Aylin Kurt, Ebru Cirban Ekrem, Betül Akkoç, Fatma Dinç
Nurses have important responsibilities in the development of health and care services for children with intellectual disabilities. This is because it is usually the nurse who first encounters the child in all kinds of care and treatment services. Barriers to the provision of sexual healthcare by nurses have not yet been clearly discovered. This study aimed to identify the barriers experienced by nurses regarding communication for sexual health education for children with intellectual disabilities. This study was carried out with 19 nurses through in-depth interviews...
2024: International Journal of Developmental Disabilities
https://read.qxmd.com/read/38475768/the-short-and-longer-term-effects-of-brief-behavioral-parent-training-versus-care-as-usual-in-children-with-behavioral-difficulties-study-protocol-for-a-randomized-controlled-trial
#36
JOURNAL ARTICLE
Roos S van Doornik, Saskia van der Oord, Joli Luijckx, Annabeth P Groenman, Patty Leijten, Marjolein Luman, Pieter J Hoekstra, Barbara J van den Hoofdakker, Tycho J Dekkers
BACKGROUND: The access to and uptake of evidence-based behavioral parent training for children with behavioral difficulties (i.e., oppositional, defiant, aggressive, hyperactive, impulsive, and inattentive behavior) are currently limited because of a scarcity of certified therapists and long waiting lists. These problems are in part due to the long and sometimes perceived as rigid nature of most evidence-based programs and result in few families starting behavioral parent training and high dropout rates...
March 12, 2024: BMC Psychiatry
https://read.qxmd.com/read/38463363/risk-stratification-in-gastric-cancer-lung-metastasis-utilizing-an-overall-survival-nomogram-and-comparing-it-with-previous-staging
#37
JOURNAL ARTICLE
Zhi-Ren Chen, Mei-Fang Yang, Zhi-Yuan Xie, Pei-An Wang, Liang Zhang, Ze-Hua Huang, Yao Luo
BACKGROUND: Gastric cancer (GC) is prevalent and aggressive, especially when patients have distant lung metastases, which often places patients into advanced stages. By identifying prognostic variables for lung metastasis in GC patients, it may be possible to construct a good prediction model for both overall survival (OS) and the cumulative incidence prediction (CIP) plot of the tumour. AIM: To investigate the predictors of GC with lung metastasis (GCLM) to produce nomograms for OS and generate CIP by using cancer-specific survival (CSS) data...
February 27, 2024: World Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38458561/safer-bars-a-cluster-randomized-effectiveness-evaluation-of-alcohol-related-sexual-violence-prevention-through-bar-staff-bystander-training
#38
JOURNAL ARTICLE
Kelly Cue Davis, Mary P Koss, Elise C Lopez, Karyn Roberts
BACKGROUND: Sexual assault is consistently associated with social contexts that support high levels of alcohol consumption such as alcohol-serving establishments (i.e., bars). The significant rates of alcohol-involved sexual assault among college students demonstrate the critical need for evidence-based efforts to reduce alcohol-involved sexual assault in this population. Although bystander approaches have demonstrated some promise for reducing alcohol-involved sexual assault, to date no published studies have examined the effectiveness of implementing bystander prevention approaches with bar staff...
March 6, 2024: Contemporary Clinical Trials
https://read.qxmd.com/read/38457597/nomogram-model-for-predicting-early-recurrence-for-resectable-pancreatic-cancer-a-multicenter-study
#39
MULTICENTER STUDY
Quan Man, Huifang Pang, Yuexiang Liang, Shaofei Chang, Junjin Wang, Song Gao
Pancreatic cancer is a highly aggressive malignancy that is characterized by early metastasis, high recurrence, and therapy resistance. Early recurrence after surgery is one of the important reasons affecting the prognosis of pancreatic cancer. This study aimed to establish an accurate preoperative nomogram model for predicting early recurrence (ER) for resectable pancreatic adenocarcinoma. We retrospectively analyzed patients who underwent pancreatectomy for pancreatic ductal adenocarcinoma between January 2011 and December 2020...
March 8, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38456749/pendah-program-for-parents-with-children-with-attention-deficit-hyperactivity-disorder-french-adaptation-of-a-behavioral-parent-training-group-pilot-study
#40
JOURNAL ARTICLE
Jerome Marquet-Doleac, Maelle Biotteau, Marie Tardy, Marion Broquere, Emmanuelle Marizy, Nathalie Faure-Marie, Noemie Lafin, Sebastien Dejean, Yves Chaix
Behavioral parent training (BPT) is recognized as an effective part of the care offered to children with attention deficit hyperactivity disorder (ADHD). The aim of this pilot study was to objectively examine the effect that this intervention may have on motor activity, in addition to the measures classically found in this type of study. Parents of 24 school-aged children (6-12 year) with ADHD who met eligibility criteria were enrolled in the study. Before, after and five months after the intervention, we used three-dimensional accelerometers over one-week periods to measure the children's motor activity, and questionnaires for parental stress, quality of life, ADHD symptoms, anxiety and sensory disorders...
March 8, 2024: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
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