keyword
https://read.qxmd.com/read/38647041/diagnostic-model-for-proliferative-hcc-using-li-rads-assessing-therapeutic-outcomes-in-hepatectomy-and-tki-ici-combination
#1
JOURNAL ARTICLE
Mengtian Lu, Zuyi Yan, Qi Qu, Guodong Zhu, Lei Xu, Maotong Liu, Jifeng Jiang, Chunyan Gu, Ying Chen, Tao Zhang, Xueqin Zhang
BACKGROUND: Proliferative hepatocellular carcinoma (HCC), aggressive with poor prognosis, and lacks reliable MRI diagnosis. PURPOSE: To develop a diagnostic model for proliferative HCC using liver imaging reporting and data system (LI-RADS) and assess its prognostic value. STUDY TYPE: Retrospective. POPULATION: 241 HCC patients underwent hepatectomy (90 proliferative HCCs: 151 nonproliferative HCCs), divided into the training (N = 167) and validation (N = 74) sets...
April 22, 2024: Journal of Magnetic Resonance Imaging: JMRI
https://read.qxmd.com/read/38646033/intraosseous-access-in-the-resuscitation-of-patients-with-trauma-the-good-the-bad-the-future
#2
REVIEW
Zaffer A Qasim, Bellal Joseph
The timely restoration of lost blood in hemorrhaging patients with trauma, especially those who are hemodynamically unstable, is of utmost importance. While intravenous access has traditionally been considered the primary method for vascular access, intraosseous (IO) access is gaining popularity as an alternative for patients with unsuccessful attempts. Previous studies have highlighted the higher success rate and easier training process associated with IO access compared with peripheral intravenous (PIV) and central intravenous access...
2024: Trauma Surgery & Acute Care Open
https://read.qxmd.com/read/38639614/identification-of-prognostic-markers-of-glioblastoma-through-bioinformatics-analysis
#3
JOURNAL ARTICLE
Jieying Wen, Haojie Zheng, Xi Yuan, Cuilan Huang, Xiaogang Yang, Zhiying Lin, Guanglong Huang
OBJECTIVE: Glioblastoma is the most common and aggressive type of the central nervous system cancers. Although radiotherapy and chemotherapy are used in the treatment of glioblastoma, survival rates remain unsatisfactory. This study aimed to explore differentially expressed genes (DEGs) based on the survival prognosis of patients with glioblastoma and to establish a model for classifying patients into different risk groups for overall survival. METHODS: DEGs from 160 tumor samples from patients with glioblastoma and 5 nontumor samples from other patients in The Cancer Genome Atlas database were identified...
April 18, 2024: Alternative Therapies in Health and Medicine
https://read.qxmd.com/read/38638522/treatment-of-aggression-regulation-problems-with-virtual-reality-study-protocol-for-a-randomized-controlled-trial
#4
JOURNAL ARTICLE
Bas R van Wolffelaar, Joan E van Horn, Larissa M Hoogsteder
BACKGROUND: Aggressive conduct among delinquents presents a pervasive issue, bearing substantial implications for not only society at large but also for the victims and the individuals displaying the aggression. Traditional approaches to treating aggression regulation deficiencies generally employ Cognitive Behavioral Therapy (CBT) in conjunction with analog role-playing exercises. A body of research supports the efficacy of various therapeutic models for aggression regulation, including Responsive Aggression Regulation Therapy (Re-ART)...
2024: Frontiers in Psychology
https://read.qxmd.com/read/38633778/an-atlas-of-causal-and-mechanistic-drivers-of-interpatient-heterogeneity-in-glioma
#5
Serdar Turkarslan, Yu He, Parvinder Hothi, Carl Murie, Abran Nicolas, Kavya Kannan, James H Park, Min Pan, Alaa Awawda, Zachariah D Cole, Mark A Shapiro, Timothy J Stuhlmiller, Hwahyung Lee, Anoop P Patel, Charles Cobbs, Nitin S Baliga
Grade IV glioma, formerly known as glioblastoma multiforme (GBM) is the most aggressive and lethal type of brain tumor, and its treatment remains challenging in part due to extensive interpatient heterogeneity in disease driving mechanisms and lack of prognostic and predictive biomarkers. Using mechanistic inference of node-edge relationship (MINER), we have analyzed multiomics profiles from 516 patients and constructed an atlas of causal and mechanistic drivers of interpatient heterogeneity in GBM (gbmMINER)...
April 7, 2024: medRxiv
https://read.qxmd.com/read/38625419/prediction-of-prostate-cancer-aggressiveness-using-magnetic-resonance-imaging-radiomics-a-dual-center-study
#6
JOURNAL ARTICLE
Nini Pan, Liuyan Shi, Diliang He, Jianxin Zhao, Lianqiu Xiong, Lili Ma, Jing Li, Kai Ai, Lianping Zhao, Gang Huang
PURPOSE: The Gleason score (GS) and positive needles are crucial aggressive indicators of prostate cancer (PCa). This study aimed to investigate the usefulness of magnetic resonance imaging (MRI) radiomics models in predicting GS and positive needles of systematic biopsy in PCa. MATERIAL AND METHODS: A total of 218 patients with pathologically proven PCa were retrospectively recruited from 2 centers. Small-field-of-view high-resolution T2-weighted imaging and post-contrast delayed sequences were selected to extract radiomics features...
April 16, 2024: Discover. Oncology
https://read.qxmd.com/read/38613399/influence-of-emotions-on-the-aggressive-driving-behavior-of-online-car-hailing-drivers-based-on-association-rule-mining
#7
JOURNAL ARTICLE
Yongfeng Ma, Yaqian Xing, Ying Wu, Shuyan Chen
Emotion is an important factor that can lead to the occurrence of aggressive driving. This paper proposes an association rule mining-based method for analysing contributing factors associated with aggressive driving behaviour among online car-hailing drivers. We collected drivers' emotion data in real time in a natural driving setting. The findings show that 29 of the top 50 association rules for aggressive driving are related to emotions, revealing a strong relationship between driver emotions and aggressive driving behaviour...
April 13, 2024: Ergonomics
https://read.qxmd.com/read/38612705/label-free-sers-of-urine-components-a-powerful-tool-for-discriminating-renal-cell-carcinoma-through-multivariate-analysis-and-machine-learning-techniques
#8
JOURNAL ARTICLE
Bogdan Adrian Buhas, Valentin Toma, Jean-Baptiste Beauval, Iulia Andras, Răzvan Couți, Lucia Ana-Maria Muntean, Radu-Tudor Coman, Teodor Andrei Maghiar, Rareș-Ionuț Știufiuc, Constantin Mihai Lucaciu, Nicolae Crisan
The advent of Surface-Enhanced Raman Scattering (SERS) has enabled the exploration and detection of small molecules, particularly in biological fluids such as serum, blood plasma, urine, saliva, and tears. SERS has been proposed as a simple diagnostic technique for various diseases, including cancer. Renal cell carcinoma (RCC) ranks as the sixth most commonly diagnosed cancer in men and is often asymptomatic, with detection occurring incidentally. The onset of symptoms typically aligns with advanced disease, aggressive histology, and unfavorable prognosis, and therefore new methods for an early diagnosis are needed...
March 31, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38608097/the-effect-of-joint-position-sense-therapy-on-chronic-shoulder-pain-with-central-sensitization
#9
JOURNAL ARTICLE
Xin Chen, Lisi Cha, Zhi Xuan, Weiming Zhang
BACKGROUND: Chronic shoulder pain is a common musculoskeletal problem associated with unreleased pain and functional dysfunction that can evolve into central sensitization. Some forms of manual therapy may exacerbate pain and central sensitization. This study investigated the impact of joint position sense therapy (JPST), a moderate joint proprioception training technique, on central sensitization, shoulder functional dysfunction, and pain in patients with chronic shoulder pain compared with more intense exercises or aggressive manual therapies...
April 12, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38606731/prognostic-factors-and-predictive-models-for-patients-with-lung-large-cell-neuroendocrine-carcinoma-based-on-seer-database
#10
JOURNAL ARTICLE
Wenqiang Li, Qian Huang, Xiaoyu He, Qian He, Qun Lai, Quan Yuan, Zhiping Deng
BACKGROUND: Lung Large cell neuroendocrine carcinoma (LCNEC) is a rare, aggressive, high-grade neuroendocrine carcinoma with a poor prognosis, mainly seen in elderly men. To date, we have found no studies on predictive models for LCNEC. METHODS: We extracted data from the Surveillance, Epidemiology, and End Results (SEER) database of confirmed LCNEC from 2010 to 2018. Univariate and multivariate Cox proportional risk regression analyses were used to identify independent risk factors, and then we constructed a novel nomogram and assessed the predictive effectiveness by receiver operating characteristic (ROC) curves, calibration curves, and decision curve analysis (DCA)...
April 2024: Clinical Respiratory Journal
https://read.qxmd.com/read/38606483/improving-employee-safety-through-a-comprehensive-patient-behavioral-program
#11
JOURNAL ARTICLE
Amanda Laprime, Rebecca Kanaley, Amy Keller, Steve J Stephen, Jan Schriefer, Anne Fallon, Tina Sosa
BACKGROUND: Health care workers in the United States are facing increasing rates of exposure to aggressive behavior, resulting in an increase in employee injuries related specifically to patient behavioral events. By leveraging interprofessional collaboration and system-level innovation, we aimed to reduce the rate of employee injuries related to patient behavioral events at a children's hospital by 50% over a 3-year period. METHODS: An interdisciplinary quality improvement team comprising physicians, behavior analysts, nursing, and other key stakeholders developed a comprehensive behavior program in our children's hospital...
April 12, 2024: Hospital Pediatrics
https://read.qxmd.com/read/38603975/impact-of-statutory-revisions-to-family-petitioned-civil-commitment-in-south-korea
#12
JOURNAL ARTICLE
Hyunsung Oh, Yunhwa Cho, Jinyeong Bae, Lynn C Holley, Michael Shafer, Kyejung Kim, Yongpyo Lee
INTRODUCTION: This study examined the impact of statutory revisions in 2016 which aimed to enhance procedural justice within the process of civil commitment for persons diagnosed with mental illnesses (PDMI) in South Korea. These changes included requiring that PDMI pose a threat of danger to self or others and the need for treatment simultaneously as criteria for petitioning civil commitment. Additionally, the revision established a public entity to oversee the legitimacy of petitions to involuntarily commit PDMI to inpatient treatment...
April 10, 2024: International Journal of Law and Psychiatry
https://read.qxmd.com/read/38601436/development-of-a-haematological-indices-based-nomogram-for-prognostic-prediction-and-immunotherapy-response-assessment-in-primary-pulmonary-lymphoepithelioma-like-carcinoma-patients
#13
JOURNAL ARTICLE
Hui Sheng, Xin He, Zhiqiang Chen, Kewei Huang, Jingjing Yang, Xiaoli Wei, Minjie Mao
BACKGROUND: Primary pulmonary lymphoepithelioma-like carcinoma (PPLELC) is a rare yet aggressive malignancy. This study aims to investigate a deep learning model based on hematological indices, referred to as haematological indices-based signature (HIBS), and propose multivariable predictive models for accurate prognosis prediction and assessment of therapeutic response to immunotherapy in PPLELC. METHODS: This retrospective study included 117 patients with PPLELC who received immunotherapy and were randomly divided into a training (n=82) and a validation (n=35) cohort...
March 29, 2024: Translational Lung Cancer Research
https://read.qxmd.com/read/38600482/barriers-and-facilitators-to-care-for-agitation-and-or-aggression-among-persons-living-with-dementia-in-long-term-care
#14
JOURNAL ARTICLE
Britney Wong, Zahinoor Ismail, Jennifer Watt, Jayna Holroyd-Leduc, Zahra Goodarzi
BACKGROUND: Agitation and/or aggression affect up to 60% of persons living with dementia in long-term care (LTC). It can be treated via non-pharmacological and pharmacological interventions, but the former are underused in clinical practice. In the literature, there is currently a lack of understanding of the challenges to caring for agitation and/or aggression among persons living with dementia in LTC. This study assesses what barriers and facilitators across the spectrum of care exist for agitation and/or aggression among people with dementia in LTC across stakeholder groups...
April 11, 2024: BMC Geriatrics
https://read.qxmd.com/read/38599293/development-and-evaluation-of-a-prediction-model-for-peripheral-artery-disease-related-major-adverse-limb-events-using-novel-biomarker-data
#15
JOURNAL ARTICLE
Ben Li, Rakan Nassereldine, Abdelrahman Zamzam, Muzammil H Syed, Muhammad Mamdani, Mohammed Al-Omran, Rawand Abdin, Mohammad Qadura
BACKGROUND: Prognostic tools for individuals with peripheral artery disease (PAD) remain limited. We developed prediction models for 3-year PAD related major adverse limb events (MALE) using demographic, clinical, and biomarker data previously validated by our group. METHODS: We performed a prognostic study using a prospectively recruited cohort of PAD patients (n = 569). Demographic/clinical data were recorded including sex, age, comorbidities, previous procedures, and medications...
April 8, 2024: Journal of Vascular Surgery
https://read.qxmd.com/read/38598816/designing-implementation-strategies-for-the-inclusion-of-lgbtqia-and-key-populations-content-in-undergraduate-nursing-curricula-in-kwazulu-natal-south-africa-protocol-for-a-multi-methods-research-project
#16
JOURNAL ARTICLE
Celenkosini Nxumalo, Zamasomi Prudence Busisiwe Luvuno, Hlolisile Wilbroda Chiya, Silingene Joyce Ngcobo, Deshini Naidoo, Sophia Zamudio-Haas, Orlando Harris
BACKGROUND: Literature suggests that Lesbian, Gay, Bisexual, Transgender, Intersex, Queer and Allied (LGBTQIA+) individuals encounter challenges with access and engagement with health services. Studies have reported that LGBTQIA+ individuals' experiences stigma, discrimination and health workers' micro aggression when accessing healthcare. There is compelling evidence to suggest that the LGBTQIA+ community are faced with disproportionate rates of HIV infection, mental health disorders, substance abuse and other non-communicable diseases...
January 24, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38596829/employing-machine-learning-to-enhance-fracture-recovery-insights-through-gait-analysis
#17
JOURNAL ARTICLE
Mostafa Rezapour, Rachel B Seymour, Stephen H Sims, Madhav A Karunakar, Nahir Habet, Metin Nafi Gurcan
This study aimed to explore the potential of gait analysis coupled with supervised machine learning models as a predictive tool for assessing post-injury complications such as infection, malunion, or hardware irritation among individuals with lower extremity fractures. We prospectively identified participants with lower extremity fractures at a tertiary academic center. These participants underwent gait analysis with a chest-mounted inertial measurement unit device. Using customized software, the raw gait data were preprocessed, emphasizing 12 essential gait variables...
April 10, 2024: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://read.qxmd.com/read/38584372/discrimination-between-benign-and-malignant-gallbladder-lesions-on-enhanced-ct-imaging-using-radiomics
#18
JOURNAL ARTICLE
Ying-Ying Zhuang, Yun Feng, Dan Kong, Li-Li Guo
BACKGROUND: Gallbladder cancer is a rare but aggressive malignancy that is often diagnosed at an advanced stage and is associated with poor outcomes. PURPOSE: To develop a radiomics model to discriminate between benign and malignant gallbladder lesions using enhanced computed tomography (CT) imaging. MATERIAL AND METHODS: All patients had a preoperative contrast-enhanced CT scan, which was independently analyzed by two radiologists. Regions of interest were manually delineated on portal venous phase images, and radiomics features were extracted...
April 7, 2024: Acta Radiologica
https://read.qxmd.com/read/38575888/a-multisite-feasibility-randomized-clinical-trial-of-mindfulness-based-resilience-training-for-aggression-stress-and-health-in-law-enforcement-officers
#19
JOURNAL ARTICLE
Michael Christopher, Sarah Bowen, Katie Witkiewitz, Daniel Grupe, Richard Goerling, Matthew Hunsinger, Barry Oken, Tyrus Korecki, Nils Rosenbaum
BACKGROUND: Law enforcement officers (LEOs) are exposed to significant stressors that can impact their mental health, increasing risk of posttraumatic stress disorder, burnout, at-risk alcohol use, depression, and suicidality. Compromised LEO health can subsequently lead to aggression and excessive use of force. Mindfulness training is a promising approach for high-stress populations and has been shown to be effective in increasing resilience and improving mental health issues common among LEOs...
April 4, 2024: BMC complementary medicine and therapies
https://read.qxmd.com/read/38571454/development-and-validation-of-an-imageless-machine-learning-algorithm-for-the-initial-screening-of-prostate-cancer
#20
JOURNAL ARTICLE
Nicolas Martelin, Brian De Witt, Benjamin Chen, Pascal Eschwège
PURPOSE: Prostate specific antigen (PSA) testing is a low-cost screening method for prostate cancer (PCa). However, its accuracy is limited. While progress is being made using medical imaging for PCa screening, PSA testing can still be improved as an easily accessible first step in the screening process. We aimed to develop and validate a new model by further personalizing the analysis of PSA with demographic, medical history, lifestyle parameters, and digital rectal examination (DRE) results...
April 4, 2024: Prostate
keyword
keyword
158996
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.