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Glaucoma , cataract,

Chungkwon Yoo, Behzad Amoozgar, Kyung-Sook Yang, Ji-Hye Park, Shan C Lin
To investigate the relationship between glaucoma severity and intraocular pressure (IOP) reduction after cataract surgery in patients with medically controlled primary open-angle glaucoma (POAG).Retrospective case series.This study included glaucoma suspects (GS) and POAG patients who underwent cataract surgery and continued to use the same glaucoma medications during the postoperative period of 4 months. The main outcomes were percent and absolute IOP changes calculated using the preoperative IOP and the postoperative IOP at 3 months...
October 2018: Medicine (Baltimore)
Moon Jeong Lee, Jiangxia Wang, David S Friedman, Michael V Boland, Carlos G De Moraes, Pradeep Y Ramulu
OBJECTIVE: To determine the association between physical activity levels and the rate of visual field (VF) loss in glaucoma. DESIGN: Longitudinal, observational study. PARTICIPANTS: Older adults with suspect or manifest glaucoma. METHODS: Participants wore accelerometers for one week to define average steps per day, minutes of moderate-to-vigorous activity (MVPA) and minutes of non-sedentary activity. All available VF measurements before and after physical activity assessment were retrospectively analyzed to measure rates of VF loss...
October 10, 2018: Ophthalmology
Reza Dana, John L Bradley, Annie Guerin, Irina Pivneva, Amber M Evans, Ipek Özer Stillman
PURPOSE: To assess the proportion of comorbidities in patients with dry eye disease (DED) compared with matched patients without DED in a comprehensive US population. DESIGN: Retrospective case-control study METHODS: Health care records for insurance claims data, detailing medical services incurred by military personnel, their families and dependents in military and civilian facilities across the United States from January 1, 2003 to March 31, 2015, were obtained from the Department of Defense (DOD) Military Health System (MHS)...
October 9, 2018: American Journal of Ophthalmology
Raquel Esteves Marques, Nuno Pinto Ferreira, David Cordeiro Sousa, Joana Pinto, André Barata, Paula Sens, Luís Abegão Pinto
PURPOSE: XEN® gel stent is a minimally invasive surgical device aimed at creating a subconjunctival drainage of aqueous humor, thereby reducing intraocular pressure (IOP). Being a novel device, doubts remain regarding the efficacy and safety of its implantation in the early stage of new users. This paper illustrates the XEN® implantation learning curve, assessed through several surgeons of different expertise. METHODS: Retrospective study on the first 6 XEN® implants performed by each of 10 certified ophthalmic surgeons...
October 11, 2018: Journal of Glaucoma
Tamara V Azizova, Nobuyuki Hamada, Evgeniya S Grigoryeva, Evgeny V Bragin
This study is the first to report cataract type specific risks in a cohort of Russian Mayak Production Association workers following chronic occupational exposure to ionizing radiation. In this retrospective cohort study, 22,377 workers (females 25.4%) first employed in 1948-1982 were followed up till the end of 2008. All cataract subtypes were significantly dependent on sex, attained age, diabetes mellitus, myopia and glaucoma. For each of posterior subcapsular (PSC), cortical and nuclear cataracts, the risk of cataract incidence significantly linearly increased with increasing radiation dose...
October 10, 2018: European Journal of Epidemiology
Josianne C Ten Berge, Zainab Fazil, Ingeborgh van den Born, Roger C W Wolfs, Marco W J Schreurs, Wim A Dik, Aniki Rothova
PURPOSE: To analyse intraocular cytokine levels and prevalence of intraocular antiretinal antibodies (ARAs) in patients with retinitis pigmentosa (RP), age-related macular degeneration (AMD), glaucoma and cataract, and correlate the results to clinical manifestations. METHODS: We collected intraocular fluid samples from patients with RP (n = 25), AMD (n = 12), glaucoma (n = 28) and cataract (n = 22), and serum samples paired with the intraocular fluids from patients with RP (N = 7) and cataract (n = 10)...
October 8, 2018: Acta Ophthalmologica
Wei-Ning Ku, Chun-Ju Lin, Yi-Yu Tsai
We report the rescue effects of adalimumab (HUMIRA® ) therapy in a case of refractory pediatric panuveitis complicated with steroid-induced glaucoma. A 13-year-old girl had suffered from blurred vision since January 2013. Bilateral idiopathic panuveitis with macular edema (ME) was diagnosed. She had previously been treated with systemic steroids, methotrexate, cyclosporine, and mycophenolate. All treatments had failed to suppress the ocular inflammation and ME persisted. Intravitreal dexamethasone implant injections were given to both eyes and ME subsided; however, complications with steroid-induced glaucoma and cataract occurred...
July 2018: Taiwan Journal of Ophthalmology
Katarzyna Tubek, Tomasz Berus, Robert Leszek
INTRODUCTION: We report a case of patient who underwent bilateral eyeball tattoo procedure for cosmetic purpose complicated with intraocular dye injection which led to ocular inflammation, secondary glaucoma, and cataract. CASE DESCRIPTION: A 21-year-old female presented to emergency department with severe right eye pain and photophobia 21 days after conjunctival tattooing procedure. Slit-lamp examination revealed right-sided eyelid edema and black deposits of tattoo ink under the bulbar conjunctiva...
October 4, 2018: European Journal of Ophthalmology
Jost B Jonas, Wen Bin Wei, Liang Xu, Ya Xing Wang
PURPOSE: Systemic inflammation is potentially associated with ocular diseases such as late age-related macular degeneration (AMD). Using the serum concentration of high-sensitive C-reactive protein (hs-CRP) as surrogate of systemic inflammation, we examined potential associations between the serum hs-CRP concentration and the presence and degree of eye diseases. METHODS: The population-based Beijing Eye Study included 3468 Chinese individuals. The study participants underwent a standardized interview and a detailed ophthalmic examination...
2018: PloS One
Maceda Gurabardhi, Heike Häberle, Henning Aurich, Liliana Werner, Duy-Thoai Pham
PURPOSE: To report clinical findings and light microscopic results of 71 opacified hydrophilic acrylic intraocular lenses (IOLs). SETTING: Vivantes Klinikum Neukoelln, Ophthalmology Department, Berlin, Germany. DESIGN: Retrospective case series. METHODS: Sixty-three patients (71 eyes) were referred to the clinic because of vision-impairing IOL opacification between December 2012 and September 2016 after routine cataract surgery elsewhere...
September 29, 2018: Journal of Cataract and Refractive Surgery
Hiromasa Yamashita, Kenkichi Tanioka, Goichiro Miyake, Ichiro Ota, Toru Noda, Kensaku Miyake, Toshio Chiba
Background: We have developed a new compact lightweight 8K ultra-high-definition (UHD; 7,680×4,320 pixels) camera and started medical application with an ophthalmic surgical microscope which is interchangeable with the conventional high-definition (1,920×1,080 pixels)/4K UHD (3,840×2,160 pixels) microscopic camera. Methods: We did a feasibility study to apply our 8K UHD microscope in cataract surgery, glaucoma surgery and vitreous surgery using pig cadaver eyes...
2018: Clinical Ophthalmology
Nichelle Warren, Rupal H Trivedi, M Edward Wilson
PURPOSE: Outcomes and reoperation rates in infants with unilateral persistent fetal vasculature (PFV) with elongated or stretched ciliary processes have not been extensively studied and were excluded from the Infant Aphakia Treatment Study (IATS). The purpose of this study is to analyze the pre-operative measurements, reoperation rates, and complications after surgery in unilateral anterior PFV with stretched processes. DESIGN: Retrospective case series METHODS: Inclusion criteria consisted of unilateral cataract surgery prior to 7 months of age and anterior PFV with elongated ciliary processes...
September 26, 2018: American Journal of Ophthalmology
Sophia Y Wang, Kuldev Singh, Joshua D Stein, Robert T Chang
Importance: The iStent Trabecular Micro-Bypass (Glaukos Corporation) is a minimally invasive glaucoma implant used in conjunction with cataract surgery to lower intraocular pressure. Objective: To determine whether implantation of the iStent concurrent with cataract surgery is associated with reduced use of ocular antihypertensive medications in a US health care claims database. Design, Setting, and Participants: Retrospective, observational longitudinal cohort study of individuals enrolled in a US managed care network who underwent iStent implantation with cataract surgery (iStent/CEIOL) from 2012 to 2016 (n = 1509 bilateral and n = 1462 unilateral surgery)...
September 27, 2018: JAMA Ophthalmology
Anselm G M Jünemann, Bernhard Michalke, Marianna Lucio, Anwar Chaudhri, Ursula Schlötzer-Schrehardt, Robert Rejdak, Marek Rękas, Bettina Hohberger
PURPOSE: Selenium supplementation was seen to be linked to glaucoma disease in a previous study (Lillico A. JE, Reid M et al. (2002) Selenium Supplementation and Risk of Glaucoma in the NPC trial University of Arizona, Tucson, AZ., Arizona Cancer Center). As aqueous humor levels of selenium seemed to be associated with primary open-angle glaucoma (POAG), the aim of this study was to analyze concentrations of selenium in aqueous humor samples of patients with POAG and pseudoexfoliation glaucoma (PEXG) in comparison to normal samples...
December 2018: Journal of Trace Elements in Medicine and Biology
Kritika Nayak, Manju Misra
Eye is the unique sense organ with complex and sophisticated anatomy and physiology. Being most instrumental for vision, it is secured by varied protective barriers; ranging from static (membranous) to dynamic (vascular) barrier. Although these barriers are very efficient to protect eye from exogenous substances and external stress, it is caught by various irreversible vision impairing ailments like cataract, conjunctivitis, glaucoma, uveitis, diabetic retinopathy (DR), diabetic macular edema (DME), age related macular degeneration (AMD), cytomegalovirus (CMV) retinitis, retinitis pigmentosa (RP), retinal vein occlusion (RVO), endophthalmitis affecting both anterior and posterior segment of eye...
November 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Rachida Bouhenni, Mirela Krasniqi, Jeffrey Dunmire, Evan Lagouros, Todd Woodruff, James Bates, Deepak P Edward
PURPOSE: To determine the five-year success rate for Baerveldt glaucoma implant (BGI) in patients who received the implant as a primary (primary BGI, used as the initial surgical procedure) or secondary (secondary BGI, used after trabeculectomy) by a single surgeon between year 1994 and 2010. PATIENTS AND METHODS: A total of 117 eyes from patients who underwent BGI placement as a primary or secondary procedure were included in this study. Demographics, previous history, type of glaucoma, intraocular pressure (IOP), visual acuity (VA), glaucoma medication use, and early and late postoperative complications were collected...
September 25, 2018: Journal of Glaucoma
Alastair Porteous, Laura Crawley
BACKGROUND: This case highlights the important sequelae that can occur following the inadvertent implantation of a single-piece intraocular lens into the ciliary sulcus during cataract surgery; secondary pigment dispersion glaucoma, recurrent anterior uveitis and macular oedema. CASE PRESENTATION: A 67-year-old lady underwent routine left cataract surgery in a separate unit but subsequently attended our eye casualty with recurrent hypertensive anterior uveitis. She was found to have secondary pigment dispersion glaucoma as the intraocular lens had been inadvertently placed into the ciliary sulcus...
September 14, 2018: BMC Ophthalmology
Ibrahim Masri, Jonathan M Smith, Nicholas K Wride, Saurabh Ghosh
BACKGROUND: Suprachoroidal haemorrhage is a rare complication of either medical anticoagulation treatment or intraocular surgical procedures. Suprachoroidal haemorrhages often have devastating visual outcome despite conservative and/or surgical intervention. CASE PRESENTATION: A patient with known Open Angle Glaucoma and Atrial Fibrillation on warfarin presents symptoms and signs suggestive acute angle closure. Examination reveals the underlying cause is a large, macula involving, spontaneous suprachoroidal haemorrhage secondary to loss of anti-coagulation control...
September 14, 2018: BMC Ophthalmology
Naoki Tojo, Mitsuya Otsuka, Atsushi Hayashi
PURPOSE: Cataract surgeries have been shown to reduce intraocular pressure. We used a Sensimed Triggerfish® contact lens sensor to compare intraocular pressure levels and their fluctuation between before and after cataract surgeries in patients with normal-tension glaucoma. METHODS: This was a prospective open-label study. Thirteen patients with normal-tension glaucoma were included. All patients underwent a 1-month washout and discontinued glaucoma medications during this study...
September 26, 2018: European Journal of Ophthalmology
Dennis Lam, Jacky Lee, Enne Leung, Shirley Liu, Julianna Yuan, Vineet Ratra
Phacoemulsification (phaco) for cataract extraction is 1 of the most commonly performed ophthalmic surgeries. With increasing evidence of significant intraocular pressure (IOP) reduction after phaco, the paradigm for glaucoma treatment has been shifting toward more cataract extraction instead of glaucoma surgery; thus, the population of glaucoma patients undergoing phaco is likely to continue to increase in the coming years. Although the safety of surgery has improved over the years with newer technologies and machines, postoperative IOP spike remains an important condition even after an uneventful operation...
September 26, 2018: Asia-Pacific Journal of Ophthalmology
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