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vessel spasm

Zhimin Li, Jun Gao, Tianyu Wang, Yongning Li
To investigate effects of microvascular decompression (MVD) surgical treatment on hemifacial spasm.A retrospective analysis of 320 adult patients (95 male cases, 29.7% and 225 female cases, 70.3%) with hemifacial spasm treated by surgery was conducted between February 2007 to June 2016, with an average age of 49.3 years and average disease course of 4.9 years. All the 320 cases of patients received MVD. After surgery, all patients were followed up for an average of 2.3 years. Surgical effects were evaluated based on the patients' symptoms and signs...
October 2018: Medicine (Baltimore)
Mitsuru Kahata, Masato Otsuka, Shohei Kataoka, Kyoichiro Yazaki, Asako Kumagai, Koji Inoue, Hiroshi Koganei, Kenji Enta, Yasuhiro Ishii
A 39-year-old woman with no coronary risk factors was admitted due to repetitive morning chest pain. Coronary angiography revealed subtotal occlusion of the distal obtuse marginal branch that was not recanalized by intracoronary nitroglycerin administration. Intravascular ultrasound and optical frequency domain imaging showed tandem intramural hematomas in the culprit vessel. We performed cutting balloon angioplasty successfully with dual intracoronary imaging modality guidance. The 4-month follow-up angiography revealed favorable vascular healing and the provocation test induced multiple spasms, including in the culprit vessel, by intracoronary acetylcholine administration...
December 2017: Journal of Cardiology Cases
Asuka Ueno, Atsuhiko Kawabe, Takushi Sugiyama, Mayuko Ishikawa, Atsuko Uema, Masahiro Shimoyama, Yasuto Horie, Toshiyasu Hoshi, Hiroyuki Sugimura, Takanori Yasu
Coronary spastic angina (CSA) is relatively more common in young people than in elderly people. Here, we present three cases of elderly male patients who experienced out-of-hospital cardiac arrest (OHCA) likely due to coronary spasm-induced ventricular fibrillation (Vf) from 2013 to 2016. After defibrillation, emergency coronary arteriography demonstrated severe coronary vasospasm that resolved following intracoronary infusion of nitroglycerin in the right coronary arteries in all three patients, with no organic obstructive lesion in the coronary arteries after nitroglycerin infusion...
November 2017: Journal of Cardiology Cases
Pei Zhang, M Helmy Selim, Haiyan Wang, Wei Kuang, Miaojing Wu, Chenxing Ji, Guowen Hu, Lei Wu, Xingen Zhu, Hua Guo
OBJECT: The compression of the offending vessel upon the facial nerve at root exit zone (REZ) is considered as the leading cause of hemifacial spasm (HFS). However, the correlation between the severity of spasm and the pressure of neurovascular compression (NVC) has not yet been investigated. The aim of this study was to investigate the clinical correlation between the severity of HFS and the pressure of NVC. METHODS: A prospective study was performed, which included 52/151 patients who underwent microvascular decompression (MVD)...
September 24, 2018: World Neurosurgery
Xian Wang, Hongmei Li, Xiaoting Sun, Xiaohang Wang, Gangyin Wang
This study explored drug release from paclitaxel + hirudin-eluting balloons in a healthy pig coronary artery model and objectively evaluated the vascular reactivity after balloon intervention. A total of 12 healthy white pigs were used for the analysis of drug release from the experimental balloon. The observational time-points included immediately following implantation and day 7, 30, and 180 after surgery. At each time-point, two pigs were treated with the paclitaxel + hirudin-eluting balloon and one with the B...
October 2018: Experimental and Therapeutic Medicine
Suraj Kumar Kulkarni, Shivakumar Bhairappa, Abdul Mujeer, Prakash Sadashivappa Surhonne
Coronary artery ectasia (CAE) is defined as a localised or diffuse dilatation of coronary artery lumen more than 1.5 times that of an adjacent normal segment. CAE may present with or without functionally significant stenosis. Such patients may manifest with stable angina or with acute coronary syndrome. Ectasia may serve as a nidus for thrombus formation with likelihood of distal embolisation or it may lead to dissection or spasm. This condition presents a challenge for an interventionist. Should we intervene or manage it medically...
September 14, 2018: BMJ Case Reports
Xiaofeng Jiang, Min Wu, Fang He, Sun Kegui, Zhuang Hongxia, Xianming Fu, Chaoshi Niu
BACKGROUND: Microvascular decompression (MVD) is the most effective treatment for hemifacial spasm (HFS). However, when encountering hemifacial spasm associated with vertebral artery, the procedure is more challenging and requires complicated operation techniques. The authors retrospectively analyzed the clinical characteristics of this group of cases and investigated reasonable transposition procedure for different anatomic classifications. METHODS: We retrospectively analyzed 117 cases underwent their first MVD for HFS between June 2010 and December 2016, which had all associated with vertebral artery compression diagnosed by preoperational radiology examination...
August 22, 2018: World Neurosurgery
Ben A Strickland, Joshua Bakhsheshian, Robert C Rennert, Vance L Fredrickson, Jordan Lam, Arun Amar, William Mack, Joseph Carey, Jonathan J Russin
BACKGROUND: Posterior inferior cerebellar artery (PICA) revascularization can be achieved with relative ease when a contralateral PICA is present. However, without a contralateral PICA, identification of a suitable vessel alternative can be challenging due to a size mismatch. OBJECTIVE: To propose the descending branch of the lateral circumflex femoral artery (DLCFA) to be an acceptable, if not preferred, arterial graft for PICA revascularization. METHODS: Data from patients who underwent PICA revascularization with DLCFA grafts were obtained from an institutional review board-approved prospectively maintained database with informed consent from the patients...
September 1, 2018: Operative Neurosurgery (Hagerstown, Md.)
Yan-Qiang Zhou, Yin-Tao Zhao, Xiao-Yan Zhao, Cui Liang, Ya-Wei Xu, Ling Li, Yuan Liu, Hai-Bo Yang
Finding the novel drug from the effective components of traditional Chinese herbal medicine is a hotspot of the modern pharmacological research. Hyperoside (HYP) belongs to flavonoid glycosides, and it has various properties, such as anti-inflammation, anti-spasm, anti-diuretic, antitussive, lowering blood pressure, and lowering cholesterol effects as well as protective effects for the cardiac and cerebral blood vessels. The purpose of this study was to investigate the effects of HYP on inflammatory and apoptotic responses in vascular endothelial cells stimulated by lipopolysaccharide (LPS) and further to identify the possible mechanisms underlying these effects...
April 2018: Current medical science
Nicholas Sellke, Alex Kuczmarski, Isabella Lawandy, Victoria L Cole, Afshin Ehsan, Arun K Singh, Yuhong Liu, Frank W Sellke, Jun Feng
OBJECTIVE: Cardioplegic arrest (CP) and cardiopulmonary bypass (CPB) are associated with vasomotor dysfunction of coronary arterioles in patients with diabetes (DM) undergoing cardiac surgery. We hypothesized that DM may up-regulate vasopressin receptor expression and alter the contractile response of coronary arterioles to vasopressin in the setting of CP/CPB. METHODS: Right atrial tissue samples of patients with DM and without (ND) (n = 8 in each group) undergoing cardiac surgery were harvested before and after CP/CPB...
June 8, 2018: Journal of Thoracic and Cardiovascular Surgery
Rebecca Knackstedt, James Gatherwright, Raffi Gurunluoglu
INTRODUCTION: There is a hesitancy to utilize vasopressors in microsurgical reconstruction due to fear of vessel spasm and subsequent flap compromise. Although there are large literature reviews analyzing vasopressor usage in head and neck reconstruction, this has not been extrapolated to all regions of the body. The goal of this study was to perform a meta-analysis examining vasopressor usage and risk of complications in microsurgical reconstruction for all recipient sites. MATERIALS AND METHODS: A meta-analysis was conducted for articles discussing the utilization of vasopressors in microsurgical reconstruction...
July 29, 2018: Microsurgery
Christopher R Honey, Murray D Morrison, Manraj K S Heran, Baljinder S Dhaliwal
Inducible laryngeal obstruction has been described under at least 40 different monikers, including vocal cord dysfunction, paroxysmal vocal fold motion, and irritable larynx. The etiology of this condition is believed to be laryngeal hyperactivity in response to psychological issues or acid reflux. Most patients are treated with some combination of proton pump inhibitors, speech therapy, and psychotherapy. However, a small cohort of patients remains refractory to all medical interventions. The authors describe a novel condition, hemi-laryngopharyngeal spasm (HELPS), which can cause severe episodic stridor leading to unconsciousness in association with cough...
July 20, 2018: Journal of Neurosurgery
Aryadi Arsyad, Elke Sokoya, Geoffrey P Dobson
New pharmacotherapies are required to improve vessel graft protection and prevent vasoconstriction and spasm in CABG surgery. Previously we have studied adenosine (A) and lidocaine (L) relaxation in rat aortic rings, and reported a possible crosstalk between L relaxation and adenosine A2a receptor inhibition. The aim of the present study was to examine the effect of AL combination compared to A and L alone on relaxation in intact and denuded rat aortic rings and in guinea-pig pressurized mesenteric arterial segments...
2018: American Journal of Translational Research
Hua Zhao, Jin Zhu, Xin Zhang, Yin-da Tang, Ping Zhou, Xu-Hui Wang, Shiting Li
BACKGROUND: Microvascular decompression (MVD) has become widely accepted as first-line therapy for hemifacial spasm. However, not all patients are candidates for the procedure, and some surgeons ignore arterioles that represent the actual underlying cause of the condition. The aim of this study was to address the role of involved arterioles in management of MVD in patients with hemifacial spasm. METHODS: Data were collected from 765 consecutive patients who underwent MVD from January 2009 to August 2010 in our hospital...
October 2018: World Neurosurgery
Jun-Hyok Oh, Seunghwan Song, Changhoon Kim, Jinhee Ahn, Jin Sup Park, Hye Won Lee, Jung Hyun Choi, Han Cheol Lee, Kwang Soo Cha, Taek Jong Hong
BACKGROUND: This study aimed to evaluate the effect of adenosine on epicardial coronary artery diameter during ergonovine provocation testing. METHODS: A total of 158 patients who underwent an ergonovine provocation test with intracoronary adenosine injection between 2011 and 2014 were selected. Patients were divided into four groups based on the severity of percent diameter stenosis following intracoronary ergonovine administration: Group 1, induced spasm < 50%; Group 2, 50-89%; Group 3, 90-99%; and Group 4, total occlusion...
July 16, 2018: Cardiology Journal
Lun-Xin Liu, Yan-Ming Ren, Peng-Wei Ren, Mei-Mei Yang, Jiang-Zhou You, Liang-Xue Zhou, Heng Zhang
OBJECTIVE: The aim of this study was to identify potential prognostic factors of hemifacial spasm (HFS) after microvascular decompression (MVD), to establish the appropriate way to tackle postprocedure symptoms and complications (PPSCs), and to find the incidence and duration of PPSCs. METHODS: Two hundred and forty-eight patients with HFS were monitored between December 2009 and December 2014. The mean follow-up duration was 24 months (range, 6-67 months). We divided patients based on their PPSC status and investigated the following factors: age, sex, spasm side, facial nerve block before MVD (botulinum toxin treatment), acupuncture before MVD, duration of HFS, hypertension, diabetes, hepatitis B virus (HBV) infection status, herpes simplex virus infection status, smoking status and alcohol use, offending vessels, Chiari malformation, electrophysiologic monitoring results, and postoperative HFS...
October 2018: World Neurosurgery
Toru Satoh, Takanobu Yagi, Keisuke Onoda, Masahiro Kameda, Tatsuya Sasaki, Tomotsugu Ichikawa, Isao Date
OBJECTIVE Offending vessels at the site of neurovascular contact (NVC) in patients with trigeminal neuralgia (TN) and hemifacial spasm (HFS) may have specific hemodynamic features. The purpose of this study was to investigate the wall shear stress (WSS) of offending vessels at NVCs by conducting a computational fluid dynamics (CFD) analysis. METHODS The authors retrospectively analyzed the cases of 20 patients (10 with TN and 10 with HFS) evaluated by 3D CT angiography and used the imaging findings for analysis of the hemodynamic parameters...
July 6, 2018: Journal of Neurosurgery
Jiang Liu, Peng Liu, Ying Zuo, Xiaoli Xu, Hongju Liu, Rose Du, Yanbing Yu, Yue Yuan
OBJECTIVE: Although classical hemifacial spasm (HFS) has been attributed to an atraumatic pulsatile vascular compression around the root exit zone (REZ) of the facial nerve, rare tumor-related HFS associated with meningiomas, epidermoid tumors, lipomas, and schwannomas in the cerebellopontine angle have been reported. The exact mechanism and the necessity of microvascular decompression for tumor-induced HFS is not clear, especially for vestibular schwannomas. METHODS: We retrospectively analyzed 10 patients with vestibular schwannomas out of 5218 cases of hemifacial spasm between 2004 and 2014...
August 2018: World Neurosurgery
M Sindou, P Mercier
Primary hemifacial spasm with few exceptions is due to the vascular compression of the facial nerve that can be evidenced with high resolution MRI. Microvascular decompression is the only curative treatment for this pathology. According to literature review detailed in chapter "conflicting vessels", the compression is located at the facial Root Exit Zone (REZ) in 95% of the cases, and in 5% distally at the cisternal or the intrameatal portion of the root as the sole conflict or in addition to one at brainstem/REZ...
May 2018: Neuro-Chirurgie
Kazuma Tashiro, Hiroyoshi Mori, Hiromoto Sone, Yousuke Takei, Masahiro Sasai, Atsuo Maeda, Tokutada Sato, Hiroshi Suzuki
No abstract text is available yet for this article.
November 2018: Coronary Artery Disease
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