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Acute renal insufficiency

Steve M D'Souza, Christopher L Stout, Emilia Krol, David J Dexter, Sadaf Sadie Ahanchi, Jean M Panneton
PURPOSE: To compare outcomes of outpatient tibial artery procedures between an office endovascular center and a hospital angiography suite. METHODS: A retrospective review was conducted of 204 outpatient tibial interventions performed on 161 patients (mean age 72±11.5 years; 81 men) in either an office (n=100) or hospital (n=104) angiography suite from April 2011 through September 2013. Patients who had an existing ipsilateral bypass that was completely proximal to the tibial trifurcation were eligible, as were patients with prior proximal endovascular interventions...
October 15, 2018: Journal of Endovascular Therapy
Guoli Sun, Pengyuan Chen, Kun Wang, Hualong Li, Shiqun Chen, Jin Liu, Yibo He, Feier Song, Yong Liu, Ji-Yan Chen
Abnormal hemodynamics is thought to contribute to the increased risk of contrast-induced nephropathy (CIN) and mortality. However, few studies focused on patients without abnormal hemodynamics (defined as hypotension, intra-aortic balloon pump usage) and reduced left ventricular ejection fraction (LVEF < 40%). Our study was to explore the impact of CIN on mortality in patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI) with relative stable hemodynamics. In this observational study, we included 696 patients with AMI undergoing PCI without reduced LVEF and abnormal hemodynamics...
October 15, 2018: Angiology
Hai-Jun Wang, Quan-Jin Si, Yang Shi, Yan Guo, Yan Li, Yu-Tang Wang
Background: The present study aimed to investigate the effects of serum beta-2 microglobulin (B2M) on the risks of major cardiovascular events (MACEs) and all-cause death in Chinese elderly isolated systolic hypertension (ISH) patients without severe renal insufficiency (estimated glomerular filtration rate [eGFR] <30 ml/min/1.73 m2 ). Materials and Methods: Serum B2M concentration, creatinine-eGFR, and blood pressure variability were evaluated in 460 elderly patients (mean age, 82...
2018: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
Jonathan Maurice Chemouny, Aurélie Sannier, Guillaume Hanouna, Laure Champion, Francois Vrtovsnik, Eric Daugas
RATIONALE: Malakoplakia is a rare disease characterized by the presence of nongranulomatous macrophage infiltration. In most cases, it affects the urinary tract. Malakoplakia can cause acute kidney injury when it is localized in the kidneys. PATIENT CONCERNS: Here, we report the case of a 65-year-old female patient with renal malakoplakia responsible for hypercalcemia. During her initial assessment, she was also diagnosed 25-OH vitamin D insufficiency, for which she was prescribed oral cholecalciferol...
October 2018: Medicine (Baltimore)
Irina Benenson, Frederick Andrew Waldron, Shelly A Jones Dillon, Shreni N Zinzuwadia, Nkehci Mbadugha, Natali Vicente, Ela Aris, Adedamola M Adeboye, Christine Makdisi
AIM: The aim of this study was to identify risk factors for hypertensive emergencies in diabetic patients presenting with severely elevated blood pressure. METHODS: Using electronic medical records, this study identified diabetic patients with hypertensive crisis who presented to the emergency department of Newark Beth Israel Medical Center, Newark, NJ from June 2013 to May 2016. Diabetic patients with hypertensive emergencies were compared with non-diabetic patients based on important demographic and clinical characteristics...
October 4, 2018: Clinical and Experimental Hypertension: CHE
Nicholas W Lange, David M Salerno, Chelsea M Sammons, Arun B Jesudian, Elizabeth C Verna, Robert S Brown
BACKGROUND: To investigate the impact of delayed calcineurin inhibitor (CNI) initiation in liver transplant recipients (LTR) with peri-operative renal insufficiency receiving basiliximab induction, we compared renal outcomes of LTR stratified by the degree of achieved post-operative renal recovery (RR) prior to CNI initiation. METHODS: All adult LTR transplanted between 01/2007 and 12/2015 who received basiliximab were included. Patients who received multi-organ transplantations, were repeat transplant recipients, or expired prior to post-operative day (POD) 90 were excluded...
October 1, 2018: Clinical Transplantation
Laura K Young, Shona Z Matthew, J Graeme Houston
OBJECTIVES: Recent safety concerns regarding gadolinium-based contrast agents (GdCAs) concluded with the suspension of some agents from the European market, yet a clinical consequence remains unknown. We used electronic health records to investigate the incidence of potential toxicity to gadoteric acid (Dotarem®) within our local population, including those with renal insufficiency (RI). METHODS: Data for patients who underwent contrast-enhanced MRI were identified, stratified by renal function at time of scan and retrospectively followed using routinely collected health data...
October 1, 2018: European Radiology
Fabrice Barlesi, Johan Vansteenkiste, David Spigel, Hidenobu Ishii, Marina Garassino, Filippo de Marinis, Mustafa Özgüroğlu, Aleksandra Szczesna, Andreas Polychronis, Ruchan Uslu, Maciej Krzakowski, Jong-Seok Lee, Luana Calabrò, Osvaldo Arén Frontera, Barbara Ellers-Lenz, Marcis Bajars, Mary Ruisi, Keunchil Park
BACKGROUND: Antibodies targeting the immune checkpoint molecules PD-1 or PD-L1 have demonstrated clinical efficacy in patients with metastatic non-small-cell lung cancer (NSCLC). In this trial we investigated the efficacy and safety of avelumab, an anti-PD-L1 antibody, in patients with NSCLC who had already received platinum-based therapy. METHODS: JAVELIN Lung 200 was a multicentre, open-label, randomised, phase 3 trial at 173 hospitals and cancer treatment centres in 31 countries...
September 21, 2018: Lancet Oncology
Jordan Gainey, Brice Blum, Bekah Bowie, Keiko Cooley, Lee Madeline, Ervin Lowther Ervin, Thomas I Nathaniel
BACKGROUND: Clinical risk factors related to not administering thrombolysis to acute ischemic stroke patients with incidence dyslipidemia is not clear. This issue was investigated in telestroke and non-telestroke settings. METHODS: We analyzed retrospective data collected from a stroke registry to compare exclusion risk factors in the telestroke and non-telestroke. We performed multivariate analysis was performed to identify risk factors that may result in exclusion from rtPA...
September 27, 2018: Lipids in Health and Disease
Azeem Tariq Malik, Jeffery Kim, Elizabeth Yu, Safdar N Khan
OBJECTIVE: To assess the impact of fixation to pelvis on 30-day outcomes following posterior spinal fusions in pediatric spine deformities. METHODS: The 2012-2016 American College of Surgeons - National Surgical Quality Improvement Program (ACS-NSQIP) Pediatric database was queried using Current Procedural Terminology codes for patients undergoing posterior spinal fusions (22800, 22802 and 22804). Patients undergoing concurrent anterior fusion/combined fusion and anterior-only fusions were removed from the study...
September 24, 2018: World Neurosurgery
Mary J Kwasny, Adam I Edelstein, David W Manning
BACKGROUND: Elevated body mass index (BMI) is considered a risk factor for complications after THA and TKA. Stakeholders have proposed BMI cutoffs for those seeking arthroplasty. The research that might substantiate BMI cutoffs is sensitive to the statistical methods used, but the impact of the statistical methods used to model BMI has not been defined. QUESTIONS/PURPOSES: (1) How does the estimated postarthroplasty risk of minor and major complications vary as a function of the statistical method used to model BMI? (2) What is the prognostic value of BMI for predicting complications with each statistical method? METHODS: Using the American College of Surgeons National Surgical Quality Improvement Program from 2005 to 2012, we investigated the impact of BMI on major and minor complication risk for THA and TKA...
September 25, 2018: Clinical Orthopaedics and related Research
L Llauger, J Jacob, G Corominas Lasalle, J Puig Martorell, P González Casquet, A Bullo N Chia
No abstract text is available yet for this article.
October 2018: Emergencias: Revista de la Sociedad Española de Medicina de Emergencias
Simella Provatopoulou, Marios Papasotiriou, Evangelos Papachristou, Hariklia Gakiopoulou, Markos Marangos, Dimitrios S Goumenos
Brucellosis is the most common zoonotic disease in Greece, with an endemic distribution and can affect any organ. Infiltration of the renal parenchyma causes acute and chronic interstitial nephritis with granulomas, whereas renal glomeruli are rarely affected. The disease has been sporadically reported, and it causes various histopathologic patterns. Herein, we describe the case of a 39-year-old stock breeder with a history of recurrent episodes of bacteremia caused by Brucella melitensis over a period of 3 years...
September 2018: Kidney Research and Clinical Practice
Jeong Eun Lee, Kyung-Hwa Kwak
RATIONALE: Although the survival period of patients who undergo liver transplantation is improving due to advances in surgical techniques and medical treatment, there is a lack of detailed, sufficient data that compare the choice of anesthetic agent in post-liver transplant surgery to avoid liver injury. PATIENT CONCERNS: The authors describe acute liver injury observed in a 61-year-old man who underwent liver transplantation surgery 13 years previously and who was on immunosuppressive therapy...
September 2018: Medicine (Baltimore)
B Nagaraju Naik, Ashish Bhalla, Navneet Sharma, Jitender Mokta, Surjit Singh, Prakamya Gupta, Ashutosh Rai, Sridhar Subbiah, Anil Bhansali, Pinaki Dutta
Purpose: Endocrinal insufficiency caused by vasculotoxic snake envenomation is under-recognized and is mostly confined to a specific geographic area. We conducted a prospective study to determine the prevalence and pattern of pituitary-target gland insufficiencies caused by snake envenomation. Materials and Methods: The hormonal evaluation of patients who had suffered from vasculotoxic snake envenomation was done at baseline and at 6 months of follow-up. Those patients with a documented hormonal insufficiency underwent magnetic resonance imaging (MRI) of the hypothalamo-pituitary area...
September 2018: Neurology India
Siu-Hin Wan, Joshua P Slusser, David O Hodge, Horng H Chen
Objective: To determine the risks of acute kidney injury development and long-term clinical outcomes of patients with hypertensive crisis. Patients and Methods: This was a population study of Olmsted County residents with hypertensive crisis between January 1, 2000, and December 31, 2008, with follow-up until June 30, 2016. Results: The results demonstrated that those with underlying chronic kidney disease upon admission for hypertensive crisis, defined as a systolic blood pressure above 180 mm Hg or diastolic blood pressure above 120 mm Hg, were more likely to develop acute kidney injury during hospitalization (odds ratio, 6...
June 2018: Mayo Clinic proceedings. Innovations, quality & outcomes
Chun Zhang, Ting Lin, Jingyao Zhang, Huan Liang, Ying Di, Na Li, Jie Gao, Wenjing Wang, Sinan Liu, Zheng Wang, Hongli Jiang, Chang Liu
OBJECTIVE: To evaluate the clinical effect and safety of regional citrate anticoagulation (RCA) in continuous renal replacement therapy (CRRT) for acute kidney injury (AKI) after hepatectomy. METHODS: A retrospective analysis of the clinical data of all patients with AKI after hepatectomy for CRRT admitted to surgical intensive care unit (ICU) of the First Affiliated Hospital of Xi'an Jiaotong University from January 19th, 2013 to January 19th, 2018 was performed...
August 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Huijie Yu, Lingfang Zhang, Songao Xu, Jun Xu, Hui Sun, Xiangyun Zhu, Xiaoqin Xu, Weizhong Cao
OBJECTIVE: To observe the effects of insulin caliper for blood glucose control on glycemic central tendency, fluctuation and incidence of hypoglycemia, etc., in emergent and critical patients to evaluate its application value. METHODS: A prospective single-blinded randomized parallel controlled intervention study was conducted. One hundred patients with severe hyperglycemia requiring treatment with insulin infusion admitted to emergency department and intensive care unit (ICU) of the First Hospital of Jiaxing from November 2015 to November 2017 were enrolled, and they were divided into the caliper group (used patented product insulin calipers for blood glucose control to adjust insulin dose for blood glucose control) and the conventional group (used paper-based insulin dose modification scheme to adjust insulin dose for blood glucose control) on average by random number table, 50 in each group...
August 2018: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
Laura Mauri, Ajay J Kirtane, Stephan Windecker, Robert W Yeh, Harold L Dauerman, Matthew J Price, Thomas Christen, Dominic J Allocco, Ian T Meredith, Dean J Kereiakes
BACKGROUND: While extended dual antiplatelet therapy (DAPT) with aspirin and a platelet (P2Y12 ) inhibitor after percutaneous coronary intervention (PCI) reduces the risk of stent thrombosis (ST) and myocardial infarction (MI), it also increases bleeding. Newer generation drug-eluting stents with bioabsorbable polymer coatings may reduce thrombotic events and allow abbreviated DAPT in selected patients. The EVOLVE Short DAPT study is designed to evaluate the safety of 3-month DAPT in high bleeding risk subjects treated with the SYNERGY bioabsorbable polymer everolimus-eluting stent...
August 17, 2018: American Heart Journal
Rachel S Bronheim, Eric K Oermann, David S Bronheim, John M Caridi
BACKGROUND: The Revised Cardiac Risk Index (RCRI) was designed to predict risk for cardiac events following non-cardiac surgery. However, there is a paucity of literature that directly addresses the relationship between RCRI and non-cardiac outcomes following posterior lumbar decompression (PLD). The objective of this study is to determine the ability of RCRI to predict non-cardiac adverse events following PLD. METHODS: ACS-NSQIP was utilized to identify patients undergoing PLD from 2006-2014...
September 12, 2018: World Neurosurgery
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