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National institutes of health stroke scale

Maria José Melo Ramos-Lima, Ismênia de Carvalho Brasileiro, Tamires Layane de Lima, Pedro Braga-Neto
OBJECTIVES: The aim of the study was to analyze the impact of ischemic stroke on health-related quality of life (QoL) and associate this event with individuals' clinical and sociodemographic characteristics. METHODS: We investigated the clinical and demographic aspects of stroke patients. The Modified Rankin Scale, National Institutes of Health Stroke Scale (NIHSS) and the Stroke Specific Quality of Life Scale (SS-QoL) were used for correlation analysis. RESULTS: Among 131 patients with ischemic stroke, 53...
October 8, 2018: Clinics
Ling-Cong, Hong-Zhao, Yu-Wang, Yu-Li, Xin-Sui
OBJECTIVE: The present study aims to investigate whether hyperhomocysteinemia (HHcy) affects the outcomes of the thrombolytic treatment for patients with AIS. METHODS: A sample of 120 AIS patients were recruited and grouped according to their serum homocysteine (Hcy) levels. The National Institute of Health Stroke Scale (NIHSS) was obtained before treatment and 7 days after it to evaluate neurological outcomes; modified Rankin Scale (mRS) was obtained 12 weeks later to assess functional outcomes...
May 2018: Revista da Associação Médica Brasileira
Julia Schubert, Otto W Witte, Utz Settmacher, Thomas E Mayer, Albrecht Günther, Jürgen Zanow, Carsten M Klingner
Ischemic stroke due to an acute occlusion of the extracranial internal carotid artery (eICA) is associated with high morbidity and mortality. The best treatment option remains unclear. This study aims to increase the available therapeutic experience documented for surgical recanalization of acute eICA occlusions. We retrospectively reviewed all hospital records of the University Hospital Jena between 2006 and 2018 to identified patients with acute ischemic stroke due to an occlusion of the eICA who underwent emergent surgical recanalization...
October 9, 2018: Vascular and Endovascular Surgery
Allison Navis, Rocio Garcia-Santibanez, Maryna Skliut
BACKGROUND: Rate of ischemic strokes and transient ischemic attacks (TIAs) increases with age. There is lack of evidence on how age affects treatment strategies and outcomes. Our aim is to compare epidemiology of ischemic strokes and TIAs in adult and geriatric populations including risk factors, treatment delivered, and outcomes. DESIGN: We designed a retrospective cross-sectional review of patients admitted to neurology with diagnosis of stroke or TIA from 2010 to 2015...
October 6, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Yang Wang, Shiyu Hu, Lijie Ren, Zhihao Lei, Tao Lan, Jingjing Cai, Chao Li
INTRODUCTION: Lipoprotein-associated phospholipase A2 (Lp-PLA2 ) is a well-known risk factor of atherosclerotic vascular diseases. Nevertheless, its role in the acute phase of ischemic stroke is still unclear. The aim of this study is to identify the relationship between Lp-PLA2 levels and early neurological deterioration (END) in acute ischemic stroke patients with Trial of Org 10 172 in Acute Stroke Treatment (TOAST) subtype of large arterial atherosclerosis (LAA). METHODS: We enrolled Chinese patients with first ever acute ischemic stroke admitted to Neurology Department of Shenzhen Second People's Hospital within 48 h from onset of symptoms during January - November 2015...
October 8, 2018: Neurological Research
De-Cai Tian, Kaibin Shi, Zilong Zhu, Jia Yao, Xiaoxia Yang, Lei Su, Sheng Zhang, Meixia Zhang, Rayna J Gonzales, Qiang Liu, DeRen Huang, Michael F Waters, Kevin N Sheth, Andrew F Ducruet, Ying Fu, Min Lou, Fu-Dong Shi
OBJECTIVE: The present study was undertaken to determine the efficacy of coadministration of fingolimod with alteplase in acute ischemic stroke patients in a delayed time window. METHODS: This was a prospective, randomized, open-label, blinded endpoint clinical trial, enrolling patients with internal carotid artery or middle cerebral artery proximal occlusion within 4.5 to 6 hours from symptom onset. Patients were randomly assigned to receive alteplase alone or alteplase with fingolimod...
October 8, 2018: Annals of Neurology
Hala A Shaheen, Lamiaa I Daker, Mohammed M Abbass, Asmaa A Abd El Fattah
Background: Stroke is the third leading cause of death and leading cause of adult disability worldwide. Long-term disability is a significant problem among survivors; post-stroke inflammation is well known to contribute to the expansion of the ischemic lesion resulting in significant morbidity and disability. To study the impact of serum level of IL-8 on severity of disability in patients with acute ischemic stroke in the first 48 h post stroke. Methods: A cross-sectional case control study was conducted on 44 patients with acute ischemic stroke (in the first 48 h)...
2018: The Egyptian journal of neurology, psychiatry and neurosurgery
Yitzchok S Lederman, Clotilde Balucani, Leah R Steinberg, Charles Philip, Jason M Lazar, Jeremy Weedon, Gautam Mirchandani, Sarah Z Weingast, Giovanna Viticchi, Lorenzo Falsetti, Mauro Silvestrini, James J Gugger, David Aharonoff, Pirouz Piran, Zachary Adler, Steven R Levine
BACKGROUND: QT dispersion, maximal interlead difference in QT interval on 12-lead electrocardiogram (ECG), measures cardiac repolarization abnormalities. Data are conflicting whether QT dispersion predicts adverse outcome in acute ischemic stroke (AIS) patients. Our objective is to determine if QT dispersion predicts: (1) short-term clinical outcome in AIS, and (2) stroke location (insular versus noninsular cortex). METHODS: Admission ECGs from 412 consecutive patients with acute stroke symptoms from 2 university-based stroke centers were reviewed...
October 2, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Pierre De Marini, Sanjeev Nayak, François Zhu, Serge Bracard, René Anxionnat, Romain Tonnelet, Liang Liao, Sébastien Richard, Lisa Humbertjean, Gioia Mione, Jean-Christophe Lacour, Anne-Laure Derelle, Benjamin Gory
Background and purpose A direct aspiration first pass technique involves first-line aspiration to remove the thrombus through a large-bore aspiration catheter in large vessel strokes. The aim of this study was to assess safety and clinical outcomes with a direct aspiration first pass technique using the new ARC catheter. Methods A retrospective analysis of prospectively collected data from three university hospitals was performed between June 2016 and May 2018. The following parameters of all acute ischemic stroke interventions using the ARC catheter were analyzed: use of intravenous thrombolysis, National Institutes of Health Stroke Scale scores at presentation and discharge, successful reperfusion (modified Thrombolysis in Cerebral Infarction 2b-3), procedure duration, procedure-related complications and 90-day clinical outcome (modified Rankin Scale score)...
October 5, 2018: Interventional Neuroradiology
Zainab Magdon-Ismail, Tatiana Ledneva, Mingzeng Sun, Lee H Schwamm, Barry Sherman, Feng Qian, Janet Prvu Bettger, Ying Xian, Joel Stein
OBJECTIVE: To evaluate factors associated with 1-year mortality after discharge for acute stroke. METHODS: In this retrospective cohort study, we studied 305 patients with ischemic stroke or intracerebral hemorrhage discharged in 2010/2011. We linked Get With The Guidelines®-Stroke clinical data with New York State administrative data and used multivariate regression models to examine variables related to 1-year all-cause mortality poststroke. RESULTS: The mean age was 68...
October 3, 2018: Topics in Stroke Rehabilitation
Dolores Cocho, Sulema Yarleque, Anuncia Boltes, Jordi Espinosa, Jordi Ciurans, Claustre Pont-Sunyer, Jordi Pons
BACKGROUND: It is unclear whether very old patients benefit from stroke unit. The aim of our work was to compare the clinical outcome of patients with ischemic stroke aged either 70 or 80 (G 1) versus oldest-old greater than or equal to 81years (G 2). METHODS: Of 1187 patients admitted with stroke during 5 years in our stroke unit, we included 252 patients with independent functional status (modified Rankin scale, [mRS] ≤ 2) before the stroke. All patients underwent clinical examination, blood test, electrocardiography, brain imaging, and cerebrovascular ultrasound...
September 29, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Zhen Yan, Baosheng Fu, Dan He, Yudi Zhang, Juanjuan Liu, Xiangjian Zhang
This study aimed to study the value of oxidized low-density lipoprotein (OX-LDL) and related ratio in the diagnosis of acute cerebral infarction and the classification of acute cerebral infarction.Of the 129 patients enrolled in this study, 94 patients with acute cerebral infarction were assigned to the case group, and 35 healthy subjects were enrolled as control group (n = 35). And then the case group were divided into large-artery atherosclerosis (LAA) group (n = 61) and small-artery occlusion (SAO) group (n = 33) according to the TOAST classification standard...
September 2018: Medicine (Baltimore)
Xiao-Jing Zhao, Qun-Xi Li, Tie-Jun Liu, Da-Li Wang, Ya-Chen An, Jiang Zhang, Yan-Bo Peng, Rui-Ying Chen, Li-Sha Chang, Yan Wang, Li Zhang, Hai-Yan Fan, Xiu-Jie Wang, Fu-Xia Zheng
This study aims to investigate the predictive values of the Chinese Stroke Scale (CSS) and National Institutes of Health Stroke Scale (NIHSS) in the prognosis of patients with acute cerebral infarction.A total of 399 patients with acute cerebral infarction were assessed using CSS and NIHSS within 1 day after admission. Then, the receiver operating characteristic (ROC) curves were established, and the area under the curves of these 2 scoring systems was compared.The area under the curve of CSS and NIHSS was 0...
September 2018: Medicine (Baltimore)
Julius Griauzde, Lynda D Lisabeth, Chengwei Li, Brisa N Sanchez, Erin Case, Nelda M Garcia, Lewis B Morgenstern, Darin B Zahuranec
BACKGROUND: We evaluated 3-month neurologic, functional, cognitive, and quality of life (QOL) outcomes in intracerebral hemorrhage (ICH) overall, and by sex and ethnicity in a population-based study. METHODS: Spontaneous ICH patients were identified from the Brain Attack Surveillance in Corpus Christi project (November 2008 to December 2013). Outcomes included neurologic (National Institutes of Health Stroke Scale: range 0-42), functional (activities of daily living/instrumental activities of daily living score: range 1-4, higher worse), cognitive (Modified Mini-Mental State Examination [3MSE]: range 0-100), and QOL (short-form stroke-specific QOL scale: range 0-5, higher better)...
September 28, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Wei Chen, Ao Lin, Yalan Yu, Lei Zhang, Gui Yang, Hanning Hu, Yi Luo
BACKGROUND: Soluble ST2 (sST2) receptor is secreted and detectable in human serum, which acts as a decoy receptor for interleukin (IL)-33 to prevent IL-33-mediated Th2 immune responses. Recently, elevated serum sST2 has been found to be a novel biomarker in cardiovascular diseases such as heart failure and atherosclerosis. Here, we studied the role of sST2 in acute ischemic stroke (AIS) and its relationship with several inflammatory markers. METHODS: The study included 112 patients with first-ever acute ischemic stroke, who were admitted within 48 hours after stroke onset...
September 1, 2018: Clinical Laboratory
Ehsan Sarbazi, Parvin Sarbakhsh, Daryoush Savadi Oskooei, Mohammad Yazdchi, Saber Ghaffari-Fam, Seyed Morteza Shamshirgaran
BACKGROUND AND OBJECTIVE: Stroke is the second leading cause of death worldwide and the number of stroke cases has increased remarkably over the last 20 years. This study aimed at identifying predictors of with 6-month mortality of first-ever stroke patients and the factors contributing to it in East Azerbaijan province. MATERIALS AND METHODS: A closed cohort study was carried out from April 2014 to December 2014. All cases of first-ever diagnosed stroke were included in the study...
2018: Journal of Education and Health Promotion
Yang Liu, Xue Liang, Xiaomin Xu, Meixue Dong, Shiyu Jia, Changqi Lu, Youdong Wei
BACKGROUND: Stroke is one of the most common causes of disability and death. Higher alkaline phosphatase (ALP) levels have been associated with poor functional outcomes and mortality in previous studies. We investigated alterations in serum ALP concentrations and functional outcomes in patients with acute ischemic stroke (AIS). METHODS: Patients with first-ever AIS were recruited to participate in the study. Serum ALP levels were measured using a Cobas Integra 400 Plus automatic biochemical analyzer, and severity of stroke was evaluated using the National Institutes of Health Stroke Scale (NIHSS) score on admission...
September 26, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Luis San Román, Bijoy K Menon, Jordi Blasco, María Hernández-Pérez, Antoni Dávalos, Charles B L M Majoie, Bruce C V Campbell, Francis Guillemin, Hester Lingsma, René Anxionnat, Jonathan Epstein, Jeffrey L Saver, Henk Marquering, John H Wong, Demetrius Lopes, Gernot Reimann, Hubert Desal, Diederik W J Dippel, Shelagh Coutts, Richard du Mesnil de Rochemont, Dileep Yavagal, Jean Christophe Ferre, Yvo B W E M Roos, David S Liebeskind, Robert Lenthall, Carlos Molina, Fahad S Al Ajlan, Vivek Reddy, Dar Dowlatshahi, Sourour Nader-Antoine, Catherine Oppenheim, Alim P Mitha, Stephen M Davis, Christian Weimar, Robert J van Oostenbrugge, Erik Cobo, Timothy J Kleinig, Geoffrey A Donnan, Aad van der Lugt, Andrew M Demchuk, Olvert A Berkhemer, Anna M M Boers, Gary A Ford, Keith W Muir, B Scott Brown, Tudor Jovin, Wim H van Zwam, Peter J Mitchell, Michael D Hill, Phil White, Serge Bracard, Mayank Goyal
BACKGROUND: Evidence regarding whether imaging can be used effectively to select patients for endovascular thrombectomy (EVT) is scarce. We aimed to investigate the association between baseline imaging features and safety and efficacy of EVT in acute ischaemic stroke caused by anterior large-vessel occlusion. METHODS: In this meta-analysis of individual patient-level data, the HERMES collaboration identified in PubMed seven randomised trials in endovascular stroke that compared EVT with standard medical therapy, published between Jan 1, 2010, and Oct 31, 2017...
October 2018: Lancet Neurology
Nobuyuki Sakai, Hirotoshi Imamura, Hidemitsu Adachi, Shoichi Tani, So Tokunaga, Takayuki Funatsu, Keita Suzuki, Hiromasa Adachi, Natsuhi Sasaki, Shuhei Kawabata, Ryo Akiyama, Kazufumi Horiuchi, Nobuyuki Ohara, Tomoyuki Kono, Satoru Fujiwara, Naoki Kaneko, Satoshi Tateshima
OBJECTIVE: To describe our initial experience with the Versi Retriever for mechanical thrombectomy in patients with acute ischemic stroke. METHODS: This study is a single-center, single-arm, first-in-man registry under institutional review board control to evaluate the efficacy and safety of the new stent retriever, the Versi Retriever. Patients with acute ischemic stroke were consecutively enrolled between September and November 2017. The clinical and procedural data were retrospectively analyzed...
September 27, 2018: Journal of Neurointerventional Surgery
Batuhan Kara, Hatem Hakan Selcuk, Aysun Erbahceci Salik, Hasanagha Zalov, Omer Yildiz, Gunay Gul, Bedih Balkan
BACKGROUND: Tigertriever (Rapid Medical, Yoqneam, Israel) is a new design of stent retriever. PURPOSE: To evaluate the feasibility, safety, and efficacy of the Tigertriever in patients with acute ischemic stroke who have undergone mechanical thrombectomy. MATERIALS AND METHODS: Two different techniques-namely, standard unsheathing (SUT) and repetitive inflation-deflation (RID) techniques, were used. Modified Thrombolysis in Cerebral Infarction (mTICI) scores of 2b and 3 were considered as successful recanalization...
September 27, 2018: Journal of Neurointerventional Surgery
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