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Vision Syndrome

Soazig Le Lay, M Carmen Martinez, Ramaroson Andriantsitohaina
Extracellular vesicles (EVs) are emerging as a novel way of cell-to-cell communication and represent an attractive way to convey fundamental information between cells. EVs, released in the extracellular space, circulate via the various body fluids and modulate locally or remotely the cellular responses following their interaction with the target cells. Clinical and experimental data support their role as biomarkers and bioeffectors in diseases related to the metabolic syndrome. EVs thus hustle the traditional vision of intercellular communication, via an alternative and versatile mode of communication, and open the door to new concepts and opportunities from a therapeutic and biological point of view...
November 2018: Médecine Sciences: M/S
Ulaş Aday, Abdullah Böyük, Barış Gültürk, Mehmet Buğra Bozan
The median arcuate ligament syndrome is a rare clinical condition with no standardized method of laparoscopic treatment. Exposure of the aorto-celiac axis might be considered as the most challenging part of the surgical procedure. It is important to secure total release while enabling adequate vision as the compressing musculofibrous ligament is located in the deepest part of the aorto-celiac hiatus. A 29-year-old male patient presenting with recurrent abdominal pain and diagnosed with the median arcuate ligament syndrome underwent laparoscopic surgery...
December 2018: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
Joanna M Jefferis, Revelle Littlewood, Irene M Pepper, Simon J Hickman
We describe here a case series of six patients referred to the Neuro-ophthalmology service in Sheffield, UK with possible acute unilateral optic neuritis. Each patient had a triad of unilateral photophobia, ipsilateral retro-ocular pain, and ipsilateral loss of vision. All patients had normal ocular examinations and investigation findings with no objective structural or functional abnormalities identified. Patients were treated by weaning-off regular analgesia and, where appropriate, commencing migraine prophylaxis...
December 2018: Neuro-ophthalmology
Meredith L Greene, Judy Y Tan, Sheri D Weiser, Katerina Christopoulos, Mary Shiels, Allison O'Hollaren, Eva Mureithi, Loren Meissner, Diane Havlir, Monica Gandhi
OBJECTIVE: People living with HIV (PLWH) are living longer and developing comorbidities and aging-related syndromes. New care models are needed to address the combined burden and complexity of HIV and its comorbidities in this group. The goal of this study is to describe qualitative data from patients and providers that informed the development of a comprehensive care model for older PLWH. METHODS: Patient and provider perspectives on the clinical care and service needs of patients living and aging with HIV were explored via surveys and focus groups at a safety net HIV clinic in San Francisco...
2018: PloS One
S N Svetozarskiy, A N Andreev
Intracameral injection of cefuroxime during phacoemulsification is considered effective in preventing endophthalmitis. Its widespread usage has led to the accumulation of data on local and systemic adverse reactions. The analysis of complications of cataract surgery with cefuroxime injections described in literature has allowed identifying a few different clusters of toxic and allergic reactions to intracameral cefuroxime for the first time. These clusters included toxic anterior segment syndrome, serous retinal detachment with macular edema, retinal hemorrhagic infarction and anaphylactic reaction...
2018: Vestnik Oftalmologii
Michele Colaci, Lorenzo Malatino, Alessandro Antonelli, Poupak Fallahi, Dilia Giuggioli, Clodoveo Ferri
The term "HCV syndrome" encompasses several organ- and systemic pathophysiological states, which often recognize autoimmunity or neoplastic evolution in their pathophysiology, as well as chronic HCV infection as trigger. The clinical features of HCV patients are heterogenous, and may include endocrine or metabolic disorders, namely autoimmune thyroiditis, type 2 diabetes mellitus, and erectile/sexual dysfunctions. In this review, we summarize current knowledge on the endocrine/metabolic diseases associated with chronic HCV infection, focusing on the main concepts emerged in the recent literature in this field...
November 29, 2018: Reviews in Endocrine & Metabolic Disorders
Hernán Anlló, Jérôme Sackur
To test the specific effects of hypnosis on the attentional components of visual awareness, we developed a posthypnotic suggestion for peripheral visual inattention inspired on the "tunnel vision" symptom of the Balint Syndrome. We constructed a dual-target visibility and discrimination paradigm, in which single-digit numerical targets were placed both on the hypnotically affected peripheral space and on the remaining undisturbed central area. Results were 3-fold: (i) when compared to participants of Low hypnotic susceptibility (Lows), highly susceptible participants (Highs) presented decreased subjective visibility; (ii) Highs did not show dual-task interference from peripheral targets (an effect of unconscious processing) during hypnotic suggestion to not attend them, but Lows did; (iii) nevertheless, when asked to execute a discrimination task over these same targets, Highs performed with the same accuracy as Lows...
2018: Neuroscience of Consciousness
Chie Sotozono, Mayumi Ueta, Norihiko Yokoi
Stevens-Johnson syndrome (SJS), and its more severe variant, toxic epidermal necrolysis (TEN), are life-threatening diseases of the skin and mucous membranes. After the acute-stage damage subsides, serious visual impairment and severe dry eye remains as ocular sequelae. At the acute stage, ocular complications occur in 77% of SJS/TEN patients. In cases with pseudomembranous formation and/or epithelial defects, the risk of ocular sequelae increases. Among 13 slit-lamp microscopy images that we obtained of SJS/TEN patients at the chronic stage, the loss of corneal epithelial stem cells and severe meibomian gland involvement were found to be the most common disorders...
November 1, 2018: Investigative Ophthalmology & Visual Science
Fukutaro Mano, Stephen A LoBue, Kuo-Chung Chang, Tomiya Mano
Background: To report the multimodal imaging and histology of a case of metastatic esophageal cancer with vitreoretinal involvement resembling acute retinal necrosis (ARN) in a patient receiving systemic chemotherapy. Case presentation: A 69-year-old Japanese man with a history of stage 4 esophageal carcinoma, treated with three cycles of 5-fluorouracil (5-FU) and cisplatin (CDDP) chemotherapy as well as 30 sessions of radiation therapy, presented with new onset of blurry vision in the right eye (OD)...
2018: International Journal of Retina and Vitreous
Machteld M Oud, Brooke L Latour, Zeineb Bakey, Stef J Letteboer, Dorien Lugtenberg, Ka Man Wu, Elisabeth A M Cornelissen, Helger G Yntema, Miriam Schmidts, Ronald Roepman, Ernie M H F Bongers
Background: Mainzer-Saldino syndrome (MZSDS) is a skeletal ciliopathy and part of the short-rib thoracic dysplasia (SRTD) group of ciliary disorders. The main characteristics of MZSDS are short limbs, mild narrow thorax, blindness, and renal failure. Thus far, variants in two genes are associated with MZSDS: IFT140, and IFT172 . In this study, we describe a 1-year-old girl presenting with mild skeletal abnormalities, Leber congenital amaurosis, and bilateral hearing difficulties. For establishing an accurate diagnosis, we combined clinical, molecular, and functional analyses...
2018: Cilia
Layan Al Tawil, Sara Aldokhayel, Leena Zeitouni, Tala Qadoumi, Siham Hussein, Shaik Shaffi Ahamed
PURPOSE: To determine the prevalence of symptoms of computer vision syndrome and to identify its associated factors. The secondary objective was to assess knowledge and practices related to preventing computer vision syndrome symptoms. METHODS: The data for this cross-sectional study were collected through a self-administered questionnaire distributed to 713 female undergraduates studying business and medicine in Saudi Arabia. The questionnaire included computer vision syndrome validated symptoms and factors associated with computer vision syndrome development...
November 26, 2018: European Journal of Ophthalmology
Genevieve F Oliver, Jillian M Carr, Justine R Smith
Recently recognised forms of uveitis include intraocular inflammations that occur during or following one of several emerging infectious diseases: chikungunya fever, dengue, Zika virus disease and Ebola virus disease. Anterior, intermediate, posterior and pan- uveitis have been described in individuals infected with chikungunya virus. Persons who contract dengue or Zika viruses also may develop different types of uveitis in the course of the infection: maculopathy is a common manifestation of dengue eye disease, and Zika eye disease may cause hypertensive anterior uveitis or mimic a white dot syndrome...
November 25, 2018: Clinical & Experimental Ophthalmology
Kirti Singh, Sonal Dangda, Ankush Mutreja, Mainak Bhattacharyya, Kirti Jaisingh
Aim: To report a case of bilateral phacomatosis pigmentovascularis (PPV), in a young male,presenting with developmental glaucoma and high myopia along with systemic features of klippel trenanauy weber (KTW) syndrome. Background: The co-existence of oculodermal melanocytosis (ODM)and port-wine stain was termed PPV by Ota. Port-wine stain presents as part of Sturge-Weber syndrome (SWS). KTW presents with varicose veins and tissue hypertrophy alongwith port-wine stain...
May 2018: Journal of Current Glaucoma Practice
Jia Yin, Deborah S Jacobs
PURPOSE: To report the long-term outcome of Prosthetic Replacement of the Ocular Surface Ecosystem (PROSE) for delivery of bevacizumab in the treatment of corneal neovascularization (KNV). METHODS: Retrospective, non-comparative, interventional case series of 13 sequential patients treated for KNV at the BostonSight between 2006 and 2017. In all cases, PROSE treatment was initiated for management of ocular surface disease and patients wore PROSE consistently on a daily wear basis prior to bevacizumab treatment...
November 20, 2018: Ocular Surface
Asres Bedaso, Ephrem Geja, Mohammed Ayalew, Zewdie Oltaye, Bereket Duko
INTRODUCTION: Post-concussion syndrome (PCS) is defined as the presence of 3 or more of the following signs and symptoms after experiencing head injury such as headache, dizziness, fatigue, irritability, insomnia, difficulty of concentration or memory difficulty. In Ethiopia, even though there was no research conducted on post-concussion syndrome, it is common health problems after experiencing head trauma that affect the productive age group, which directly or indirectly influences the development of the country...
November 21, 2018: Journal of Headache and Pain
Ranju Kharel Sitaula, Anadi Khatri
BACKGROUND: Computer vision syndrome is a common global problem among millions of computer users including medical students. Medical students are preferring soft copies rather than textbooks. The aim of this study was to assess the knowledge, attitude, and practice of MBBS students about Computer vision syndrome, and to identify its ocular morbidity among them. METHODS: A descriptive cross-sectional survey based on the questionnaire was conducted among 1st- 4th year MBBS students of the Institute of Medicine and 80 students underwent detailed ocular evaluation...
October 30, 2018: Journal of Nepal Health Research Council
Bhanu P S Pangtey, Piyush Kohli, Kim Ramasamy
Wyburn-Mason syndrome is associated with unilateral retinal racemose hemangioma. Rarely, it presents with bilateral and symmetrical grade of malformation. We describe a 37-year old male, who presented with Wyburn-Mason syndrome presenting with bilateral but asymmetrical retinal hemangioma. The eye with advanced grade of hemangioma was complicated with exudation, intraretinal fluid, neurosensory detachment, and reduced vision. He was treated with one intravitreal injection of bevacizumab, after which both the intraretinal fluid and neurosensory detachment resolved...
December 2018: Indian Journal of Ophthalmology
Anton M Kolomeyer, Christopher K Hwang, Benjamin J Kim
BACKGROUND: Ibrutinib is a tyrosine kinase inhibitor commonly used in patients with chronic lymphocytic leukemia. Based on the published literature, it has a very sound ophthalmologic safety profile. In the following, we describe a case of anterior chamber fibrinoid syndrome in a patient on ibrutinib for B-cell chronic lymphocytic leukemia after uncomplicated cataract extraction. CASE PRESENTATION: A 75-year-old white man with B-cell chronic lymphocytic leukemia on ibrutinib therapy and without significant past ocular history presented 1 day after uncomplicated phacoemulsification with in-the-bag intraocular lens implantation with multiple, discrete, pigmented cords in the anterior chamber...
November 16, 2018: Journal of Medical Case Reports
S Čermáková, T Fait
OBJECTIVE: To describe unusual cause of diplopia in early puerperal period. DESIGN: Case report. SETTING: Department of Obstetrics and Gynecology, 2nd Faculty of Medicine and Faculty Hospital Motol. CASE REPORT: 34-year-old patient at 39 weeks of gestation complaining fever, headache and blurring of vision was referred to our medical center. She underwent caesarean section for tachycardia of fetus. Symptoms remained during early puerperium...
2018: Ceská Gynekologie
Patrizia Moretti, Massimo C Bachetti, Tiziana Sciarma, Alfonso Tortorella
BACKGROUND: We currently define dysphoria as a complex and disorganized emotional state with proteiform phenomenology, characterized by a multitude of symptoms. Among them prevail irritability, discontent, interpersonal resentment and surrender. Dysphoria, in line with the most recent Interpersonal Dysphoria Model, could represent a "psychopathological organizer" of the Borderline Personality Disorder. We would like to extend this theoretical concept to other psychiatric disorders in order to consider dysphoria as a possible psychopathological nucleus, a syndrome on its own...
November 2018: Psychiatria Danubina
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