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https://www.readbyqxmd.com/read/30342280/risk-factors-for-contralateral-central-lymph-node-metastasis-in-unilateral-cn0-papillary-thyroid-carcinoma-a-meta-analysis
#1
REVIEW
Binbin Yan, Yingchen Hou, Dong Chen, Jianye He, Yu Jiang
BACKGROUND: Central lymph node metastasis(CLNM) is common in papillary thyroid carcinoma(PTC). LNM is related to local recurrence and adverse prognosis. The extent of prophylactic central lymph node dissection(pCLND) is not well defined. We aim to investigate the prevalence and risk factors for contralateral central lymph node metastasis (CCLNM) in unilateral clinical node-negative (cN0) PTC patients to determine the appropriate extent of pCLND. METHODS: A systematic literature search was performed using PubMed and Embase databases until May 2018...
October 17, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/30340617/estrogen-is-involved-in-hemangioma-regression-associated-with-mast-cells
#2
Fang Hou, Yuemeng Dai, Chun-Yang Fan, James Y Suen, Gresham T Richter
BACKGROUND: Estrogen plays a role in infantile hemangioma (IH) development, but the underlying mechanism remains unclear. This study aimed to assess estrogen and estrogen receptor (ER) localization and expression levels in IH. In addition, the unexpected relationship between mast cells (MCs) and estrogen in human IH was discussed. METHODS: IH (n = 29), vascular malformation (VMs, n = 33) and normal skin (n = 15) specimens were assessed. IH was classified into proliferative (n = 9; age, 3...
October 19, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/30340513/spatial-and-temporal-clustering-analysis-of-tuberculosis-in-the-mainland-of-china-at-the-prefecture-level-2005-2015
#3
Meng-Yang Liu, Qi-Huan Li, Ying-Jie Zhang, Yuan Ma, Yue Liu, Wei Feng, Cheng-Bei Hou, Endawoke Amsalu, Xia Li, Wei Wang, Wei-Min Li, Xiu-Hua Guo
BACKGROUND: Tuberculosis (TB) is still one of the most serious infectious diseases in the mainland of China. So it was urgent for the formulation of more effective measures to prevent and control it. METHODS: The data of reported TB cases in 340 prefectures from the mainland of China were extracted from the China Information System for Disease Control and Prevention (CISDCP) during January 2005 to December 2015. The Kulldorff's retrospective space-time scan statistics was used to identify the temporal, spatial and spatio-temporal clusters of reported TB in the mainland of China by using the discrete Poisson probability model...
October 20, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/30340292/mediating-factors-explaining-the-associations-between-polycyclic-aromatic-hydrocarbons-exposure-low-socioeconomic-status-and-diabetes-a-structural-equation-modeling-approach
#4
Lu Wang, Jian Hou, Chen Hu, Yun Zhou, Huizhen Sun, Jiafei Zhang, Tian Li, Erwei Gao, Guiyang Wang, Weihong Chen, Jing Yuan
Exposure to polycyclic aromatic hydrocarbons (PAHs) is linked with increased risk of diabetes, whereas socioeconomic status (SES) may contribute to the development of diabetes. However, the mechanisms underlying the relationships between them are unclear. We used structural equation modeling (SEM) to identify mediating factors in the associations of PAHs exposure, low SES with diabetes risk. Data were collected from 2751 Wuhan participants at baseline from the Wuhan-Zhuhai Cohort Study (n = 3053). They answered the questionnaires regarding socio-demographic, participated physical examinations and provided urine samples for measurements of urinary monohydroxy-polycyclic aromatic hydrocarbons (OH-PAHs) levels...
January 15, 2019: Science of the Total Environment
https://www.readbyqxmd.com/read/30339576/the-effect-of-nsaids-exposure-on-breast-cancer-risk-in-female-patients-with-autoimmune-diseases
#5
Chih-Hsing Hung, Yi-Ching Lin, Yu-Han Chang, Yu-Chih Lin, Hsin-Yi Huang, Wei-Ju Yeh, Ting-Yi Wu, Ming-Feng Hou
Both breast cancer and autoimmune diseases (ADs) are predominant in women. NSAIDs are common medications for AD. Evidence on the association between NSAIDs use and breast cancer risk is controversial. We investigated the association between NSAIDs exposure and breast cancer risk in female patients with AD. AD patients older than 18 years of age were enrolled from Taiwan Longitudinal Health Insurance Database 2005. The NSAID users were defined as AD patients who had ever taken NSAIDs for at least 3 months between 2000 and 2009...
October 18, 2018: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/30339442/search-for-pair-produced-resonances-each-decaying-into-at-least-four-quarks-in-proton-proton-collisions-at-sqrt-s-13-tev
#6
A M Sirunyan, A Tumasyan, W Adam, F Ambrogi, E Asilar, T Bergauer, J Brandstetter, M Dragicevic, J Erö, A Escalante Del Valle, M Flechl, R Frühwirth, V M Ghete, J Hrubec, M Jeitler, N Krammer, I Krätschmer, D Liko, T Madlener, I Mikulec, N Rad, H Rohringer, J Schieck, R Schöfbeck, M Spanring, D Spitzbart, A Taurok, W Waltenberger, J Wittmann, C-E Wulz, M Zarucki, V Chekhovsky, V Mossolov, J Suarez Gonzalez, E A De Wolf, D Di Croce, X Janssen, J Lauwers, M Pieters, M Van De Klundert, H Van Haevermaet, P Van Mechelen, N Van Remortel, S Abu Zeid, F Blekman, J D'Hondt, I De Bruyn, J De Clercq, K Deroover, G Flouris, D Lontkovskyi, S Lowette, I Marchesini, S Moortgat, L Moreels, Q Python, K Skovpen, S Tavernier, W Van Doninck, P Van Mulders, I Van Parijs, D Beghin, B Bilin, H Brun, B Clerbaux, G De Lentdecker, H Delannoy, B Dorney, G Fasanella, L Favart, R Goldouzian, A Grebenyuk, A K Kalsi, T Lenzi, J Luetic, N Postiau, E Starling, L Thomas, C Vander Velde, P Vanlaer, D Vannerom, Q Wang, T Cornelis, D Dobur, A Fagot, M Gul, I Khvastunov, D Poyraz, C Roskas, D Trocino, M Tytgat, W Verbeke, B Vermassen, M Vit, N Zaganidis, H Bakhshiansohi, O Bondu, S Brochet, G Bruno, C Caputo, P David, C Delaere, M Delcourt, B Francois, A Giammanco, G Krintiras, V Lemaitre, A Magitteri, A Mertens, M Musich, K Piotrzkowski, A Saggio, M Vidal Marono, S Wertz, J Zobec, F L Alves, G A Alves, L Brito, M Correa Martins Junior, G Correia Silva, C Hensel, A Moraes, M E Pol, P Rebello Teles, E Belchior Batista Das Chagas, W Carvalho, J Chinellato, E Coelho, E M Da Costa, G G Da Silveira, D De Jesus Damiao, C De Oliveira Martins, S Fonseca De Souza, H Malbouisson, D Matos Figueiredo, M Melo De Almeida, C Mora Herrera, L Mundim, H Nogima, W L Prado Da Silva, L J Sanchez Rosas, A Santoro, A Sznajder, M Thiel, E J Tonelli Manganote, F Torres Da Silva De Araujo, A Vilela Pereira, S Ahuja, C A Bernardes, L Calligaris, T R Fernandez Perez Tomei, E M Gregores, P G Mercadante, S F Novaes, Sandra S Padula, D Romero Abad, A Aleksandrov, R Hadjiiska, P Iaydjiev, A Marinov, M Misheva, M Rodozov, M Shopova, G Sultanov, A Dimitrov, L Litov, B Pavlov, P Petkov, W Fang, X Gao, L Yuan, M Ahmad, J G Bian, G M Chen, H S Chen, M Chen, Y Chen, C H Jiang, D Leggat, H Liao, Z Liu, F Romeo, S M Shaheen, A Spiezia, J Tao, C Wang, Z Wang, E Yazgan, H Zhang, J Zhao, Y Ban, G Chen, A Levin, J Li, L Li, Q Li, Y Mao, S J Qian, D Wang, Z Xu, Y Wang, C Avila, A Cabrera, C A Carrillo Montoya, L F Chaparro Sierra, C Florez, C F González Hernández, M A Segura Delgado, B Courbon, N Godinovic, D Lelas, I Puljak, T Sculac, Z Antunovic, M Kovac, V Brigljevic, D Ferencek, K Kadija, B Mesic, A Starodumov, T Susa, M W Ather, A Attikis, M Kolosova, G Mavromanolakis, J Mousa, C Nicolaou, F Ptochos, P A Razis, H Rykaczewski, M Finger, M Finger, E Ayala, E Carrera Jarrin, Y Assran, S Elgammal, Y Mohammed, S Bhowmik, A Carvalho Antunes De Oliveira, R K Dewanjee, K Ehataht, M Kadastik, M Raidal, C Veelken, P Eerola, H Kirschenmann, J Pekkanen, M Voutilainen, J Havukainen, J K Heikkilä, T Järvinen, V Karimäki, R Kinnunen, T Lampén, K Lassila-Perini, S Laurila, S Lehti, T Lindén, P Luukka, T Mäenpää, H Siikonen, E Tuominen, J Tuominiemi, T Tuuva, M Besancon, F Couderc, M Dejardin, D Denegri, J L Faure, F Ferri, S Ganjour, A Givernaud, P Gras, G Hamel de Monchenault, P Jarry, C Leloup, E Locci, J Malcles, G Negro, J Rander, A Rosowsky, M Ö Sahin, M Titov, A Abdulsalam, C Amendola, I Antropov, F Beaudette, P Busson, C Charlot, R Granier de Cassagnac, I Kucher, S Lisniak, A Lobanov, J Martin Blanco, M Nguyen, C Ochando, G Ortona, P Pigard, R Salerno, J B Sauvan, Y Sirois, A G Stahl Leiton, A Zabi, A Zghiche, J-L Agram, J Andrea, D Bloch, J-M Brom, E C Chabert, V Cherepanov, C Collard, E Conte, J-C Fontaine, D Gelé, U Goerlach, M Jansová, A-C Le Bihan, N Tonon, P Van Hove, S Gadrat, S Beauceron, C Bernet, G Boudoul, N Chanon, R Chierici, D Contardo, P Depasse, H El Mamouni, J Fay, L Finco, S Gascon, M Gouzevitch, G Grenier, B Ille, F Lagarde, I B Laktineh, H Lattaud, M Lethuillier, L Mirabito, A L Pequegnot, S Perries, A Popov, V Sordini, M Vander Donckt, S Viret, S Zhang, T Toriashvili, Z Tsamalaidze, C Autermann, L Feld, M K Kiesel, K Klein, M Lipinski, M Preuten, M P Rauch, C Schomakers, J Schulz, M Teroerde, B Wittmer, V Zhukov, A Albert, D Duchardt, M Endres, M Erdmann, T Esch, R Fischer, S Ghosh, A Güth, T Hebbeker, C Heidemann, K Hoepfner, H Keller, S Knutzen, L Mastrolorenzo, M Merschmeyer, A Meyer, P Millet, S Mukherjee, T Pook, M Radziej, H Reithler, M Rieger, F Scheuch, A Schmidt, D Teyssier, G Flügge, O Hlushchenko, B Kargoll, T Kress, A Künsken, T Müller, A Nehrkorn, A Nowack, C Pistone, O Pooth, H Sert, A Stahl, M Aldaya Martin, T Arndt, C Asawatangtrakuldee, I Babounikau, K Beernaert, O Behnke, U Behrens, A Bermúdez Martínez, D Bertsche, A A Bin Anuar, K Borras, V Botta, A Campbell, P Connor, C Contreras-Campana, F Costanza, V Danilov, A De Wit, M M Defranchis, C Diez Pardos, D Domínguez Damiani, G Eckerlin, T Eichhorn, A Elwood, E Eren, E Gallo, A Geiser, J M Grados Luyando, A Grohsjean, P Gunnellini, M Guthoff, M Haranko, A Harb, J Hauk, H Jung, M Kasemann, J Keaveney, C Kleinwort, J Knolle, D Krücker, W Lange, A Lelek, T Lenz, K Lipka, W Lohmann, R Mankel, I-A Melzer-Pellmann, A B Meyer, M Meyer, M Missiroli, G Mittag, J Mnich, V Myronenko, S K Pflitsch, D Pitzl, A Raspereza, M Savitskyi, P Saxena, P Schütze, C Schwanenberger, R Shevchenko, A Singh, N Stefaniuk, H Tholen, O Turkot, A Vagnerini, G P Van Onsem, R Walsh, Y Wen, K Wichmann, C Wissing, O Zenaiev, R Aggleton, S Bein, L Benato, A Benecke, V Blobel, M Centis Vignali, T Dreyer, E Garutti, D Gonzalez, J Haller, A Hinzmann, A Karavdina, G Kasieczka, R Klanner, R Kogler, N Kovalchuk, S Kurz, V Kutzner, J Lange, D Marconi, J Multhaup, M Niedziela, D Nowatschin, A Perieanu, A Reimers, O Rieger, C Scharf, P Schleper, S Schumann, J Schwandt, J Sonneveld, H Stadie, G Steinbrück, F M Stober, M Stöver, D Troendle, A Vanhoefer, B Vormwald, M Akbiyik, C Barth, M Baselga, S Baur, E Butz, R Caspart, T Chwalek, F Colombo, W De Boer, A Dierlamm, N Faltermann, B Freund, M Giffels, M A Harrendorf, F Hartmann, S M Heindl, U Husemann, F Kassel, I Katkov, S Kudella, H Mildner, S Mitra, M U Mozer, Th Müller, M Plagge, G Quast, K Rabbertz, M Schröder, I Shvetsov, G Sieber, H J Simonis, R Ulrich, S Wayand, M Weber, T Weiler, S Williamson, C Wöhrmann, R Wolf, G Anagnostou, G Daskalakis, T Geralis, A Kyriakis, D Loukas, G Paspalaki, I Topsis-Giotis, G Karathanasis, S Kesisoglou, P Kontaxakis, A Panagiotou, N Saoulidou, E Tziaferi, K Vellidis, K Kousouris, I Papakrivopoulos, G Tsipolitis, I Evangelou, C Foudas, P Gianneios, P Katsoulis, P Kokkas, S Mallios, N Manthos, I Papadopoulos, E Paradas, J Strologas, F A Triantis, D Tsitsonis, M Bartók, M Csanad, N Filipovic, P Major, M I Nagy, G Pasztor, O Surányi, G I Veres, G Bencze, C Hajdu, D Horvath, Á Hunyadi, F Sikler, T Á Vámi, V Veszpremi, G Vesztergombi, N Beni, S Czellar, J Karancsi, A Makovec, J Molnar, Z Szillasi, P Raics, Z L Trocsanyi, B Ujvari, S Choudhury, J R Komaragiri, P C Tiwari, S Bahinipati, C Kar, P Mal, K Mandal, A Nayak, D K Sahoo, S K Swain, S Bansal, S B Beri, V Bhatnagar, S Chauhan, R Chawla, N Dhingra, R Gupta, A Kaur, A Kaur, M Kaur, S Kaur, R Kumar, P Kumari, M Lohan, A Mehta, K Sandeep, S Sharma, J B Singh, G Walia, A Bhardwaj, B C Choudhary, R B Garg, M Gola, S Keshri, Ashok Kumar, S Malhotra, M Naimuddin, P Priyanka, K Ranjan, Aashaq Shah, R Sharma, R Bhardwaj, M Bharti, R Bhattacharya, S Bhattacharya, U Bhawandeep, D Bhowmik, S Dey, S Dutt, S Dutta, S Ghosh, K Mondal, S Nandan, A Purohit, P K Rout, A Roy, S Roy Chowdhury, S Sarkar, M Sharan, B Singh, S Thakur, P K Behera, R Chudasama, D Dutta, V Jha, V Kumar, P K Netrakanti, L M Pant, P Shukla, T Aziz, M A Bhat, S Dugad, G B Mohanty, N Sur, B Sutar, R Kumar Verma, S Banerjee, S Bhattacharya, S Chatterjee, P Das, M Guchait, Sa Jain, S Karmakar, S Kumar, M Maity, G Majumder, K Mazumdar, N Sahoo, T Sarkar, S Chauhan, S Dube, V Hegde, A Kapoor, K Kothekar, S Pandey, A Rane, S Sharma, S Chenarani, E Eskandari Tadavani, S M Etesami, M Khakzad, M Mohammadi Najafabadi, M Naseri, F Rezaei Hosseinabadi, B Safarzadeh, M Zeinali, M Felcini, M Grunewald, M Abbrescia, C Calabria, A Colaleo, D Creanza, L Cristella, N De Filippis, M De Palma, A Di Florio, F Errico, L Fiore, A Gelmi, G Iaselli, M Ince, S Lezki, G Maggi, M Maggi, G Miniello, S My, S Nuzzo, A Pompili, G Pugliese, R Radogna, A Ranieri, G Selvaggi, A Sharma, L Silvestris, R Venditti, P Verwilligen, G Zito, G Abbiendi, C Battilana, D Bonacorsi, L Borgonovi, S Braibant-Giacomelli, R Campanini, P Capiluppi, A Castro, F R Cavallo, S S Chhibra, C Ciocca, G Codispoti, M Cuffiani, G M Dallavalle, F Fabbri, A Fanfani, P Giacomelli, C Grandi, L Guiducci, F Iemmi, S Marcellini, G Masetti, A Montanari, F L Navarria, A Perrotta, F Primavera, A M Rossi, T Rovelli, G P Siroli, N Tosi, S Albergo, A Di Mattia, R Potenza, A Tricomi, C Tuve, G Barbagli, K Chatterjee, V Ciulli, C Civinini, R D'Alessandro, E Focardi, G Latino, P Lenzi, M Meschini, S Paoletti, L Russo, G Sguazzoni, D Strom, L Viliani, L Benussi, S Bianco, F Fabbri, D Piccolo, F Ferro, F Ravera, E Robutti, S Tosi, A Benaglia, A Beschi, L Brianza, F Brivio, V Ciriolo, S Di Guida, M E Dinardo, S Fiorendi, S Gennai, A Ghezzi, P Govoni, M Malberti, S Malvezzi, A Massironi, D Menasce, L Moroni, M Paganoni, D Pedrini, S Ragazzi, T Tabarelli de Fatis, S Buontempo, N Cavallo, A Di Crescenzo, F Fabozzi, F Fienga, G Galati, A O M Iorio, W A Khan, L Lista, S Meola, P Paolucci, C Sciacca, E Voevodina, P Azzi, N Bacchetta, D Bisello, A Boletti, A Bragagnolo, R Carlin, P Checchia, M Dall'Osso, P De Castro Manzano, T Dorigo, U Dosselli, F Gasparini, F Gonella, A Gozzelino, S Lacaprara, P Lujan, M Margoni, A T Meneguzzo, J Pazzini, N Pozzobon, P Ronchese, R Rossin, A Tiko, E Torassa, M Zanetti, P Zotto, G Zumerle, A Braghieri, A Magnani, P Montagna, S P Ratti, V Re, M Ressegotti, C Riccardi, P Salvini, I Vai, P Vitulo, L Alunni Solestizi, M Biasini, G M Bilei, C Cecchi, D Ciangottini, L Fanò, P Lariccia, R Leonardi, E Manoni, G Mantovani, V Mariani, M Menichelli, A Rossi, A Santocchia, D Spiga, K Androsov, P Azzurri, G Bagliesi, L Bianchini, T Boccali, L Borrello, R Castaldi, M A Ciocci, R Dell'Orso, G Fedi, F Fiori, L Giannini, A Giassi, M T Grippo, F Ligabue, E Manca, G Mandorli, A Messineo, F Palla, A Rizzi, P Spagnolo, R Tenchini, G Tonelli, A Venturi, P G Verdini, L Barone, F Cavallari, M Cipriani, N Daci, D Del Re, E Di Marco, M Diemoz, S Gelli, E Longo, B Marzocchi, P Meridiani, G Organtini, F Pandolfi, R Paramatti, F Preiato, S Rahatlou, C Rovelli, F Santanastasio, N Amapane, R Arcidiacono, S Argiro, M Arneodo, N Bartosik, R Bellan, C Biino, N Cartiglia, F Cenna, S Cometti, M Costa, R Covarelli, N Demaria, B Kiani, C Mariotti, S Maselli, E Migliore, V Monaco, E Monteil, M Monteno, M M Obertino, L Pacher, N Pastrone, M Pelliccioni, G L Pinna Angioni, A Romero, M Ruspa, R Sacchi, K Shchelina, V Sola, A Solano, D Soldi, A Staiano, S Belforte, V Candelise, M Casarsa, F Cossutti, G Della Ricca, F Vazzoler, A Zanetti, D H Kim, G N Kim, M S Kim, J Lee, S Lee, S W Lee, C S Moon, Y D Oh, S Sekmen, D C Son, Y C Yang, H Kim, D H Moon, G Oh, J Goh, T J Kim, S Cho, S Choi, Y Go, D Gyun, S Ha, B Hong, Y Jo, K Lee, K S Lee, S Lee, J Lim, S K Park, Y Roh, H S Kim, J Almond, J Kim, J S Kim, H Lee, K Lee, K Nam, S B Oh, B C Radburn-Smith, S H Seo, U K Yang, H D Yoo, G B Yu, D Jeon, H Kim, J H Kim, J S H Lee, I C Park, Y Choi, C Hwang, J Lee, I Yu, V Dudenas, A Juodagalvis, J Vaitkus, I Ahmed, Z A Ibrahim, M A B Md Ali, F Mohamad Idris, W A T Wan Abdullah, M N Yusli, Z Zolkapli, A Castaneda Hernandez, J A Murillo Quijada, M C Duran-Osuna, H Castilla-Valdez, E De La Cruz-Burelo, G Ramirez-Sanchez, I Heredia-De La Cruz, R I Rabadan-Trejo, R Lopez-Fernandez, J Mejia Guisao, R Reyes-Almanza, M Ramirez-Garcia, A Sanchez-Hernandez, S Carrillo Moreno, C Oropeza Barrera, F Vazquez Valencia, J Eysermans, I Pedraza, H A Salazar Ibarguen, C Uribe Estrada, A Morelos Pineda, D Krofcheck, S Bheesette, P H Butler, A Ahmad, M Ahmad, M I Asghar, Q Hassan, H R Hoorani, A Saddique, M A Shah, M Shoaib, M Waqas, H Bialkowska, M Bluj, B Boimska, T Frueboes, M Górski, M Kazana, K Nawrocki, M Szleper, P Traczyk, P Zalewski, K Bunkowski, A Byszuk, K Doroba, A Kalinowski, M Konecki, J Krolikowski, M Misiura, M Olszewski, A Pyskir, M Walczak, P Bargassa, C Beirão Da Cruz E Silva, A Di Francesco, P Faccioli, B Galinhas, M Gallinaro, J Hollar, N Leonardo, L Lloret Iglesias, M V Nemallapudi, J Seixas, G Strong, O Toldaiev, D Vadruccio, J Varela, V Alexakhin, A Golunov, I Golutvin, N Gorbounov, I Gorbunov, A Kamenev, V Karjavin, A Lanev, A Malakhov, V Matveev, P Moisenz, V Palichik, V Perelygin, M Savina, S Shmatov, S Shulha, N Skatchkov, V Smirnov, A Zarubin, V Golovtsov, Y Ivanov, V Kim, E Kuznetsova, P Levchenko, V Murzin, V Oreshkin, I Smirnov, D Sosnov, V Sulimov, L Uvarov, S Vavilov, A Vorobyev, Yu Andreev, A Dermenev, S Gninenko, N Golubev, A Karneyeu, M Kirsanov, N Krasnikov, A Pashenkov, D Tlisov, A Toropin, V Epshteyn, V Gavrilov, N Lychkovskaya, V Popov, I Pozdnyakov, G Safronov, A Spiridonov, A Stepennov, V Stolin, M Toms, E Vlasov, A Zhokin, T Aushev, R Chistov, M Danilov, P Parygin, D Philippov, S Polikarpov, E Tarkovskii, V Andreev, M Azarkin, I Dremin, M Kirakosyan, S V Rusakov, A Terkulov, A Baskakov, A Belyaev, E Boos, V Bunichev, M Dubinin, L Dudko, A Ershov, A Gribushin, V Klyukhin, O Kodolova, I Lokhtin, I Miagkov, S Obraztsov, S Petrushanko, V Savrin, V Blinov, T Dimova, L Kardapoltsev, D Shtol, Y Skovpen, I Azhgirey, I Bayshev, S Bitioukov, D Elumakhov, A Godizov, V Kachanov, A Kalinin, D Konstantinov, P Mandrik, V Petrov, R Ryutin, S Slabospitskii, A Sobol, S Troshin, N Tyurin, A Uzunian, A Volkov, A Babaev, S Baidali, P Adzic, P Cirkovic, D 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Arenton, P Barria, B Cox, R Hirosky, M Joyce, A Ledovskoy, H Li, C Neu, T Sinthuprasith, Y Wang, E Wolfe, F Xia, R Harr, P E Karchin, N Poudyal, J Sturdy, P Thapa, S Zaleski, M Brodski, J Buchanan, C Caillol, D Carlsmith, S Dasu, L Dodd, B Gomber, M Grothe, M Herndon, A Hervé, U Hussain, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, T Ruggles, A Savin, N Smith, W H Smith, N Woods
This Letter presents the results of a search for pair-produced particles of masses above 100 GeV that each decay into at least four quarks. Using data collected by the CMS experiment at the LHC in 2015-2016, corresponding to an integrated luminosity of 38.2  fb^{-1}, reconstructed particles are clustered into two large jets of similar mass, each consistent with four-parton substructure. No statistically significant excess of data over the background prediction is observed in the distribution of average jet mass...
October 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/30339440/observation-of-the-z%C3%A2-%C3%AF-%C3%A2-%C3%A2-decay-in-pp-collisions-at-sqrt-s-13-tev
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Pena, O Prokofyev, G Rakness, L Ristori, A Savoy-Navarro, B Schneider, E Sexton-Kennedy, A Soha, W J Spalding, L Spiegel, S Stoynev, J Strait, N Strobbe, L Taylor, S Tkaczyk, N V Tran, L Uplegger, E W Vaandering, C Vernieri, M Verzocchi, R Vidal, M Wang, H A Weber, A Whitbeck, D Acosta, P Avery, P Bortignon, D Bourilkov, A Brinkerhoff, L Cadamuro, A Carnes, M Carver, D Curry, R D Field, S V Gleyzer, B M Joshi, J Konigsberg, A Korytov, P Ma, K Matchev, H Mei, G Mitselmakher, K Shi, D Sperka, J Wang, S Wang, Y R Joshi, S Linn, A Ackert, T Adams, A Askew, S Hagopian, V Hagopian, K F Johnson, T Kolberg, G Martinez, T Perry, H Prosper, A Saha, A Santra, V Sharma, R Yohay, M M Baarmand, V Bhopatkar, S Colafranceschi, M Hohlmann, D Noonan, M Rahmani, T Roy, F Yumiceva, M R Adams, L Apanasevich, D Berry, R R Betts, R Cavanaugh, X Chen, S Dittmer, O Evdokimov, C E Gerber, D A Hangal, D J Hofman, K Jung, J Kamin, C Mills, I D Sandoval Gonzalez, M B Tonjes, N Varelas, H Wang, X Wang, Z Wu, J Zhang, M Alhusseini, B Bilki, W Clarida, K Dilsiz, S Durgut, R P Gandrajula, M Haytmyradov, V Khristenko, J-P Merlo, A Mestvirishvili, A Moeller, J Nachtman, H Ogul, Y Onel, F Ozok, A Penzo, C Snyder, E Tiras, J Wetzel, B Blumenfeld, A Cocoros, N Eminizer, D Fehling, L Feng, A V Gritsan, W T Hung, P Maksimovic, J Roskes, U Sarica, M Swartz, M Xiao, C You, A Al-Bataineh, P Baringer, A Bean, S Boren, J Bowen, A Bylinkin, J Castle, S Khalil, A Kropivnitskaya, D Majumder, W Mcbrayer, M Murray, C Rogan, S Sanders, E Schmitz, J D Tapia Takaki, Q Wang, A Ivanov, K Kaadze, D Kim, Y Maravin, D R Mendis, T Mitchell, A Modak, A Mohammadi, L K Saini, N Skhirtladze, F Rebassoo, D Wright, A Baden, O Baron, A Belloni, S C Eno, Y Feng, C Ferraioli, N J Hadley, S Jabeen, G Y Jeng, R G Kellogg, J Kunkle, A C Mignerey, F Ricci-Tam, Y H Shin, A Skuja, S C Tonwar, K Wong, D Abercrombie, B Allen, V Azzolini, A Baty, G Bauer, R Bi, S Brandt, W Busza, I A Cali, M D'Alfonso, Z Demiragli, G Gomez Ceballos, M Goncharov, P Harris, D Hsu, M Hu, Y Iiyama, G M Innocenti, M Klute, D Kovalskyi, Y-J Lee, P D Luckey, B Maier, A C Marini, C Mcginn, C Mironov, S Narayanan, X Niu, C Paus, C Roland, G Roland, G S F Stephans, K Sumorok, K Tatar, D Velicanu, J Wang, T W Wang, B Wyslouch, S Zhaozhong, A C Benvenuti, R M Chatterjee, A Evans, P Hansen, S Kalafut, Y Kubota, Z Lesko, J Mans, S Nourbakhsh, N Ruckstuhl, R Rusack, J Turkewitz, M A Wadud, J G Acosta, S Oliveros, E Avdeeva, K Bloom, D R Claes, C Fangmeier, F Golf, R Gonzalez Suarez, R Kamalieddin, I Kravchenko, J Monroy, J E Siado, G R Snow, B Stieger, A Godshalk, C Harrington, I Iashvili, A Kharchilava, D Nguyen, A Parker, S Rappoccio, B Roozbahani, G Alverson, E Barberis, C Freer, A Hortiangtham, D M Morse, T Orimoto, R Teixeira De Lima, T Wamorkar, B Wang, A Wisecarver, D Wood, S Bhattacharya, O Charaf, K A Hahn, N Mucia, N Odell, M H Schmitt, K Sung, M Trovato, M Velasco, R Bucci, N Dev, M Hildreth, K Hurtado Anampa, C Jessop, D J Karmgard, N Kellams, K Lannon, W Li, N Loukas, N Marinelli, F Meng, C Mueller, Y Musienko, M Planer, A Reinsvold, R Ruchti, P Siddireddy, G Smith, S Taroni, M Wayne, A Wightman, M Wolf, A Woodard, J Alimena, L Antonelli, B Bylsma, L S Durkin, S Flowers, B Francis, A Hart, C Hill, W Ji, T Y Ling, W Luo, B L Winer, H W Wulsin, S Cooperstein, P Elmer, J Hardenbrook, P Hebda, S Higginbotham, A Kalogeropoulos, D Lange, M T Lucchini, J Luo, D Marlow, K Mei, I Ojalvo, J Olsen, C Palmer, P Piroué, J Salfeld-Nebgen, D Stickland, C Tully, S Malik, S Norberg, A Barker, V E Barnes, S Das, L Gutay, M Jones, A W Jung, A Khatiwada, B Mahakud, D H Miller, N Neumeister, C C Peng, H Qiu, J F Schulte, J Sun, F Wang, R Xiao, W Xie, T Cheng, J Dolen, N Parashar, Z Chen, K M Ecklund, S Freed, F J M Geurts, M Kilpatrick, W Li, B Michlin, B P Padley, J Roberts, J Rorie, W Shi, Z Tu, J Zabel, A Zhang, A Bodek, P de Barbaro, R Demina, Y T Duh, J L Dulemba, C Fallon, T Ferbel, M Galanti, A Garcia-Bellido, J Han, O Hindrichs, A Khukhunaishvili, K H Lo, P Tan, R Taus, M Verzetti, A Agapitos, J P Chou, Y Gershtein, T A Gómez Espinosa, E Halkiadakis, M Heindl, E Hughes, S Kaplan, R Kunnawalkam Elayavalli, S Kyriacou, A Lath, R Montalvo, K Nash, M Osherson, H Saka, S Salur, S Schnetzer, D Sheffield, S Somalwar, R Stone, S Thomas, P Thomassen, M Walker, A G Delannoy, J Heideman, G Riley, K Rose, S Spanier, K Thapa, O Bouhali, A Castaneda Hernandez, A Celik, M Dalchenko, M De Mattia, A Delgado, S Dildick, R Eusebi, J Gilmore, T Huang, T Kamon, S Luo, R Mueller, Y Pakhotin, R Patel, A Perloff, L Perniè, D Rathjens, A Safonov, A Tatarinov, N Akchurin, J Damgov, F De Guio, P R Dudero, S Kunori, K Lamichhane, S W Lee, T Mengke, S Muthumuni, T Peltola, S Undleeb, I Volobouev, Z Wang, S Greene, A Gurrola, R Janjam, W Johns, C Maguire, A Melo, H Ni, K Padeken, J D Ruiz Alvarez, P Sheldon, S Tuo, J Velkovska, M Verweij, Q Xu, M W Arenton, P Barria, B Cox, R Hirosky, M Joyce, A Ledovskoy, H Li, C Neu, T Sinthuprasith, Y Wang, E Wolfe, F Xia, R Harr, P E Karchin, N Poudyal, J Sturdy, P Thapa, S Zaleski, M Brodski, J Buchanan, C Caillol, D Carlsmith, S Dasu, L Dodd, S Duric, B Gomber, M Grothe, M Herndon, A Hervé, U Hussain, P Klabbers, A Lanaro, A Levine, K Long, R Loveless, T Ruggles, A Savin, N Smith, W H Smith, N Woods
This Letter presents the observation of the rare Z boson decay Z→ψℓ^{+}ℓ^{-}. Here, ψ represents contributions from direct J/ψ and ψ(2S)→J/ψX, ℓ^{+}ℓ^{-} is a pair of electrons or muons, and the J/ψ meson is detected via its decay to μ^{+}μ^{-}. The sample of proton-proton collision data, collected by the CMS experiment at the LHC at a center-of-mass energy of 13 TeV, corresponds to an integrated luminosity of 35.9  fb^{-1}. The signal is observed with a significance in excess of 5 standard deviations...
October 5, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/30339387/6-benzhydryl-4-amino-quinolin-2-ones-as-potent-cannabinoid-type-1-cb1-receptor-inverse-agonists-and-chemical-modifications-for-peripheral-selectivity
#8
Yuemei Zhang, Michael Greco, Mark J Macielag, Christopher A Teleha, Renee DesJarlais, YuTing Tang, George Ho, Cuifen Hou, Cailin Chen, Shuyuan Zhao, Jack Kauffman, Raul Camacho, Jenson Qi, William Murray, Keith Demarest, James Leonard
A novel series of 6-benzhydryl-4-amino-quinolin-2-ones was discovered as cannabinoid type 1 receptor (CB1R) inverse agonists based on the high-throughput screening hit, compound 1a. Structure-activity relationships were studied to improve in vitro/in vivo pharmacology and restrict distribution to the peripheral circulation. We adopted several strategies such as increasing topological polar surface area, incorporating discrete polyethylene glycol side chains and targeting P-glycoprotein (P-gp) to minimize access to the brain...
October 19, 2018: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/30338262/higher-dispersion-measures-of-conduction-and-repolarization-in-type-1-compared-to-non-type-1-brugada-syndrome-patients-an-electrocardiographic-study-from-a-single-center
#9
Gary Tse, Ka Hou Christien Li, Guangping Li, Tong Liu, George Bazoukis, Wing Tak Wong, Matthew T V Chan, Martin C S Wong, Yunlong Xia, Konstantinos P Letsas, Gary Chin Pang Chan, Yat Sun Chan, William K K Wu
Background: Brugada syndrome (BrS) is a cardiac ion channelopathy that predisposes affected individuals to sudden cardiac death (SCD). Type 1 BrS is thought to take a more malignant clinical course than non-type 1 BrS. We hypothesized that the degrees of abnormal repolarization and conduction are greater in type 1 subjects and these differences can be detected by electrocardiography (ECG). Methods: Electrocardiographic data from spontaneous type 1 and non-type 1 BrS patients were analyzed. ECG parameters were measured from leads V1 to V3...
2018: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/30337752/-effect-of-autoclave-on-surface-microstructure-and-cyclic-fatigue-resistance-of-r-phase-rotary-instruments
#10
Y J Yang, B X Hou, X M Hou
OBJECTIVE: To compare the effects of autoclave on surface microstructure and cyclic fatigue resistance of K3XF and K3. METHODS: Forty-eight size 25, 0.06 taper 25 mm-long K3XF or K3 were randomly divided into 4 groups (n=12). The instruments from group 1 were not autoclaved, and the groups 2 to 4 underwent autoclave for 10 cycles, 20 cycles, and 30 cycles, respectively. The surface microstructure of two instruments randomly selected from each group was observed using scanning electron microscope (SEM)...
October 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/30337751/-surface-microstructure-and-cyclic-fatigue-resistance-of-electro-discharged-machining-nickel-titanium-endodontic-instrument
#11
F F Wang, Y J Yang, X M Hou
OBJECTIVE: To compare the surface microstructures and cyclic fatigue resistance of HyFlex EDM with HyFlex CM and HyFlex NT. METHODS: Twelve 25 mm-long 25#/- HyFlex EDM and twelve 25 mm-long 25#/0.06 taper HyFlex CM or HyFlex NT were selected. The surface microstructure of the 2 instruments which were randomly selected from each group was observed by using scanning electron microscope (SEM). The remaining 10 instruments from each group were submitted to the cyclic fatigue test by using a simulated stainless steel root canal with 60° angle of curvature and curvature radius of 3...
October 18, 2018: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/30335886/ebf1-gene-promotes-the-proliferation-and-inhibits-the-apoptosis-of-bone-marrow-cd34-cells-in-patients-with-myelodysplastic-syndrome-through-negative-regulation-of-mitogen-activated-protein-kinase-axis
#12
Shuang Hou, Jie Hao, Yan-Yu Wang, Bing-Bing Zhao, Gong-Wei Xiao, Yan-Qing Li, Xi Liu, Zhi-Lan Zou, Ye Yao, Hong Xiong
The transcription factor, early B cell factor 1 (EBF1), plays a vital role in the lineage specification involving early B cell development and the onset of myelodysplastic syndrome (MDS). Therefore, to investigate whether or not EBF1 affects MDS as well as the transcription factor's underlying mechanism, we used CD34+ hematopoietic stem cells in bone marrow from patients with MDS. The extracted cells were then transfected with a series of EBF1, short hairpin RNA against EBF1 (shEBF1), and SB203580 (a specific mitogen-activated protein kinase [MAPK] axis inhibitor)...
October 18, 2018: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/30335029/sevoflurane-is-an-effective-adjuvant-to-propofol-based-total-intravenous-anesthesia-for-attenuating-cough-reflex-in-nonintubated-video-assisted-thoracoscopic-surgery
#13
Hou-Chuan Lai, Tsai-Wang Huang, Wei-Cheng Tseng, Wei-Lin Lin, Hung Chang, Zhi-Fu Wu
BACKGROUND: Nonintubated video-assisted thoracic surgery (VATS) has been widely developed during the recent years. Cough reflex is an inevitably encountered problem while approaching lung lesions, and it may induce major bleeding. Sevoflurane anesthesia may attenuate cough reflex by inhibiting the pulmonary irritant receptors. However, the incidence of postoperative nausea and vomiting (PONV) in inhalational anesthesia is higher than in the propofol-based total intravenous anesthesia (TIVA)...
October 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30333742/non-vitamin-k-antagonist-oral-anticoagulants-and-cognitive-impairment-in-atrial-fibrillation-insights-from-the-meta-analysis-of-over-90-000-patients-of-randomized-controlled-trials-and-real-world-studies
#14
Chi Zhang, Zhi-Chun Gu, Long Shen, Mang-Mang Pan, Yi-Dan Yan, Jun Pu, Xiao-Yan Liu, Hou-Wen Lin
Background: The relationship between the use of non-vitamin K antagonist oral anticoagulants (NOACs) and the impairment of cognition in atrial fibrillation (AF) remains unknown. Methods: A comprehensive database search of Medline, Embase, Cochrane Library databases, and ClinicalTrials.gov Website was performed for randomized controlled trials (RCTs) reporting cognitive impairment events and observational nationwide database studies reporting adjusted hazard ratio (HR) in AF patients with NOACs. The primacy outcome was a composite of any cognitive impairment...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/30328377/beneficial-effects-of-electroacupuncture-on-neuropathic-pain-evoked-by-spinal-cord-injury-and-involvement-of-pi3k-mtor-mechanisms
#15
Yujie Wang, Yu Zhao, Xiaohui Ma, Jing Li, Junling Hou, Xiaohong Lv
The purpose of this study was to examine the beneficial effects of electroacupuncture (EA) on neuropathic pain evoked by spinal cord injury (SCI) and determine the underlying molecular mechanisms of these effects. SCI was induced in rats. Behavioral tests were performed to examine pain responses induced by mechanical and thermal stimulation. Western blot analysis was used to measure the protein expression of phosphorylated mammalian target of rapamycin (p-mTOR), mTOR-mediated phosphorylated ribosomal protein S6 kinase beta-1 (p-S6K1), and phosphorylated eukaryotic translation initiation factor 4E-binding protein 1 (p-4E-BP1) in the superficial dorsal horn of the spinal cord...
October 17, 2018: Biological Research for Nursing
https://www.readbyqxmd.com/read/30328323/effects-of-antioxidant-tempol-on-systematic-inflammation-and-endothelial-apoptosis-in-emphysematous-rats-exposed-to-intermittent-hypoxia
#16
Haiyan Zhao, Yaping Zhao, Xin Li, Leiqian Xu, Fangxin Jiang, Wanju Hou, Lixia Dong, Jie Cao
PURPOSE: Obstructive sleep apnea and chronic obstructive pulmonary disease are independent risk factors of cardiovascular disease (CVD), and their coexistence is known as overlap syndrome (OS). Endothelial dysfunction is the initial stage of CVD; however, underlying mechanisms linking OS and CVD are not well understood. The aim of this study was to explore whether OS can lead to more severe inflammation and endothelial apoptosis by promoting endothelial dysfunction, and to assess the intervention effects of antioxidant tempol...
November 2018: Yonsei Medical Journal
https://www.readbyqxmd.com/read/30327840/deficiency-of-lrp4-in-zebrafish-and-human-lrp4-mutation-induce-aberrant-activation-of-jagged-notch-signaling-in-fin-and-limb-development
#17
Jing Tian, Jinhui Shao, Cong Liu, Hsin-Yu Hou, Chih-Wei Chou, Mohammad Shboul, Guo-Qing Li, Mohammad El-Khateeb, Omar Q Samarah, Yao Kou, Yu-Hsuan Chen, Mei-Jen Chen, Zhaojie Lyu, Wei-Leng Chen, Yu-Fu Chen, Yong-Hua Sun, Yi-Wen Liu
Low-density lipoprotein receptor-related protein 4 (LRP4) is a multi-functional protein implicated in bone, kidney and neurological diseases including Cenani-Lenz syndactyly (CLS), sclerosteosis, osteoporosis, congenital myasthenic syndrome and myasthenia gravis. Why different LRP4 mutation alleles cause distinct and even contrasting disease phenotypes remain unclear. Herein, we utilized the zebrafish model to search for pathways affected by a deficiency of LRP4. The lrp4 knockdown in zebrafish embryos exhibits cyst formations at fin structures and the caudal vein plexus, malformed pectoral fins, defective bone formation and compromised kidney morphogenesis; which partially phenocopied the human LRP4 mutations and were reminiscent of phenotypes resulting form a perturbed Notch signaling pathway...
October 16, 2018: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/30326632/the-glucose-lowering-effect-of-foxtail-millet-in-subjects-with-impaired-glucose-tolerance-a-self-controlled-clinical-trial
#18
Xin Ren, Ruiyang Yin, Dianzhi Hou, Yong Xue, Min Zhang, Xianmin Diao, Yumei Zhang, Jihong Wu, Jinrong Hu, Xiaosong Hu, Qun Shen
Foxtail millet has relatively low starch digestibility and moderate glycemic index compared to other grains. Since there are still no clinical researches regarding its long-term effect on blood glucose, this self-controlled study was conducted to investigate the glucose-lowering effect of foxtail millet in free-living subjects with impaired glucose tolerance (IGT). Fifty g/day of foxtail millet was provided to enrolled subjects throughout 12 weeks and the related clinical parameters were investigated at week 0, 6 and 12, respectively...
October 15, 2018: Nutrients
https://www.readbyqxmd.com/read/30326062/effects-of-lentivirus-mediated-c3-expression-on-trabecular-meshwork-cells-and-intraocular-pressure
#19
Junkai Tan, Ning Fan, Ningli Wang, BingKai Feng, Ming Yang, Guo Liu, Yun Wang, Xianjun Zhu, Paul L Kaufman, Iok-Hou Pang, Xuyang Liu
Purpose: We evaluated the effects of lentivirus-mediated exoenzyme C3 transferase (C3) expression on cultured primary human trabecular meshwork (HTM) cells in vitro, and on rat intraocular pressure (IOP). Methods: HTM cells were cultured and treated with lentivirus vectors expressing either green fluorescent protein (GFP) only (LV-GFP) or GFP and C3 together (LV-C3-GFP). Changes in cell morphology and actin stress fibers were assessed. The vectors were also injected into the anterior chamber of rats, and GFP expression was visualized by a Micron III Retinal Imaging Microscope in vivo and a fluorescence microscope ex vivo...
October 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/30325739/inflammation-markers-are-associated-with-frailty-in-elderly-patients-with-coronary-heart-disease
#20
Ping Hou, Hui-Ping Xue, Xin-E Mao, Yong-Nan Li, Lin-Feng Wu, Yong-Bing Liu
The neutrophil-to-lymphocyte ratio (NLR) and red blood cell distribution width (RDW) are important indicators of adverse outcomes and have predictive value for many diseases; however, the relationships between frailty, and the NLR and RDW in patients with coronary heart disease (CHD) have not been determined. In this cross-sectional study, we investigated the association between frailty, and the NLR and RDW in elderly CHD patients ≥ 60 years of age. Frailty was defined according to frailty phenotype. Of 345 patients enrolled in the study, 22...
October 16, 2018: Aging
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