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https://www.readbyqxmd.com/read/30517273/evaluation-of-the-sensitivity-of-the-psychosocial-scale-of-facial-appearance-in-peripheral-facial-paralysis
#1
Mabile Francine Ferreira Silva, Stela Verzinhasse Peres, Paulo Roberto Lazarini, Maria Claudia Cunha
PURPOSE: To investigate the sensitivity and internal consistency of the Psychosocial Scale of Facial Appearance (PSFA) based on the comparison between its results and those from other facial functional assessment instruments: House-Brackmann scale (HBS) and Facial Grading System - and the psychosocial implications measured by the Hospital Anxiety and Depression Scale (HADS). METHODS: The study was approved by the Research Ethics Committee of the aforementioned Institution under protocols no...
November 29, 2018: CoDAS
https://www.readbyqxmd.com/read/30516411/-leaving-was-a-process-not-an-event-the-lived-experience-of-dating-and-domestic-violence-in-140-characters
#2
Heather L Storer, Maria Rodriguez, Roxanne Franklin
One of the most frequent refrains heard in the public discourse on intimate partner violence (IPV) is why do they stay? The literature has demonstrated that IPV victims face multiple barriers to safely exiting their relationships. Currently, there has been a limited examination of the role social media can play in elucidating the lived experience of IPV. With 25% of the population using Twitter, there are opportunities to examine its utility for deepening understandings of IPV. Using data generated from the #WhyIStayed Twitter campaign, the purpose of this study is to examine Twitter users' reasons for staying in their abusive relationships...
December 5, 2018: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/30516336/attitudes-toward-defendants-with-substance-related-charges-an-analysis-of-a-national-sample-of-criminal-defense-attorneys
#3
Joseph J Avery, Jordan Starck, Yuanda Xu, Jonathan D Avery, Joel Cooper
BACKGROUND AND OBJECTIVES: While a large percentage of criminal offenders suffer from substance use disorders (SUDs), virtually nothing is known about the attitudes criminal defense attorneys possess toward their clients who are facing substance-related charges. This is a serious concern, as the burden of steering individuals with SUDs into treatment often falls to criminal defense attorneys. The goal of this study was to examine the attitudes of criminal defense attorneys toward individuals who have been accused of drug crimes...
December 2018: American Journal on Addictions
https://www.readbyqxmd.com/read/30516320/on-the-role-of-mindfulness-and-compassion-skills-in-students-coping-well-being-and-development-across-the-transition-to-college-a-conceptual-analysis
#4
Kamila Dvořáková, Mark T Greenberg, Robert W Roeser
In this paper, we aim to integrate the current conceptual approaches to stress and coping processes during the college transition with the potential role of mindfulness and compassion skills on students' well-being and development. First, we provide an overview of the issues and challenges emerging adults are facing during the transition to college, drawing on the revised version of the transactional stress model by Lazarus and Folkman (1984). Second, we introduce a conceptual model of adaptive stress and coping processes enhanced by mindfulness and compassion (MC) skills to positively impact the appraisal and coping resources and emerging adults' mental health...
December 5, 2018: Stress and Health: Journal of the International Society for the Investigation of Stress
https://www.readbyqxmd.com/read/30515806/challenges-facing-antiangiogenesis-therapy-the-significant-role-of-hypoxia-inducible-factor-and-met-in-development-of-resistance-to-anti-vascular-endothelial-growth-factor-targeted-therapies
#5
REVIEW
Ali Mahdi, Behrad Darvishi, Keivan Majidzadeh-A, Malihe Salehi, Leila Farahmand
It is now fully recognized that along with multiple physiological functions, angiogenesis is also involved in the fundamental process and pathobiology of several disorders including cancer. Recent studies have fully established the role of angiogenesis in cancer progression as well as invasion and metastasis. Consequently, many therapeutic agents such as monoclonal antibodies targeting angiogenesis pathway have been introduced in clinic with the hope for improving the outcomes of cancer therapy. Bevacizumab (Avastin®) was the first anti-vascular endothelial growth factor (VEGF) targeting monoclonal antibody developed with this purpose and soon received its accelerated US Food and Drug Administration (FDA) approval for treatment of patients with metastatic breast cancer in 2008...
December 4, 2018: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/30515515/developmental-shifts-in-detection-and-attention-for-auditory-visual-and-audiovisual-speech
#6
Susan Jerger, Markus F Damian, Cassandra Karl, Hervé Abdi
Purpose: Successful speech processing depends on our ability to detect and integrate multisensory cues, yet there is minimal research on multisensory speech detection and integration by children. To address this need, we studied the development of speech detection for auditory (A), visual (V), and audiovisual (AV) input. Method: Participants were 115 typically developing children clustered into age groups between 4 and 14 years. Speech detection (quantified by response times [RTs]) was determined for 1 stimulus, /buh/, presented in A, V, and AV modes (articulating vs...
December 3, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/30515196/mutation-based-harmony-search-algorithm-for-hybrid-testing-of-web-service-composition
#7
Eckwijai Maythaisong, Wararat Songpan
Web service composition is a method of developing a new web service from an existing one based on business goals. Web services selected for composition should provide accurate operational results and reliable applications. However, most alternative service providers have not yet fulfilled users' needs in terms of services and processes. Service providers, in fact, have focused on enhancing nonfunctional attributes, such as efficiencies of time, cost, and availability, which still face limitations. Furthermore, it remains advantageous to compose services and suitably plan them around business plans...
2018: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/30515020/police-surgeons-and-victims-of-rape-cultures-of-harm-and-care
#8
Joanna Bourke
Between the late 1960s and the late 1980s, police surgeons found themselves under concerted attack for their treatment of victims of rape and sexual assault. This article explores the tensions they faced between the needs of victims and their legal responsibilities. Should they prioritise care or the collection of evidence? How did they respond to criticism and why were reforms inadequate? I show how institutional structures and ideologies help explain the longevity of cultures of harm within the sub-discipline of police doctors...
November 2018: Social History of Medicine: the Journal of the Society for the Social History of Medicine
https://www.readbyqxmd.com/read/30514747/night-shift-work-and-abnormal-liver-function-is-non-alcohol-fatty-liver-a-necessary-mediator
#9
Feng Wang, Liuzhuo Zhang, Suyang Wu, Wentao Li, Miaomiao Sun, Wenting Feng, Ding Ding, Samuel Yeung-Shan Wong, Peng Zhu, Greg J Evans, Yun Kwok Wing, Jihui Zhang, Jelle J Vlaanderen, Roel C H Vermeulen, Yanfang Zhang, Emily Ying-Yang Chan, Zhimin Li, Lap Ah Tse
OBJECTIVES: Accumulated evidence implies that night shift work may trigger liver dysfunction. Non-alcoholic fatty liver (NAFL) is suggested to be a necessary mediator in this process. This study aimed to examine the relationship between night shift work and elevated level of alanine transaminase (e-ALT) of workers and investigate the potential mediation effect of NAFL. METHODS: This study included all male workers from the baseline survey of a cohort of night shift workers...
December 4, 2018: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/30514531/gaetano-zumbo-s-anatomical-wax-model-from-skull-to-cranium
#10
Rose Marie San Juan
Gaetano Giulio Zumbo's anatomical model of a head, executed in the late seventeenth century and now in Florence's La Specola, is the earliest known life-size wax model for use in study and research. The model conjoins experimental wax techniques with human matter such as hair, teeth and bone, and confronts the observer not only with the interior of the head but also with the face, brutally dissected and in the process of decomposing. By contrast, the back of the head offers an entirely different display, an actual human cranium cut across its upper part and revealing carefully dissected and vibrantly modeled sections of the brain...
2018: Progress in Brain Research
https://www.readbyqxmd.com/read/30514385/oncolytic-virus-immunotherapy-future-prospects-for-oncology
#11
REVIEW
Junaid Raja, Johannes M Ludwig, Scott N Gettinger, Kurt A Schalper, Hyun S Kim
BACKGROUND: Immunotherapy is at the forefront of modern oncologic care. Various novel therapies have targeted all three layers of tumor biology: tumor, niche, and immune system with a range of promising results. One emerging class in both primary and salvage therapy is oncolytic viruses. This therapy offers a multimodal approach to specifically and effectively target and destroy malignant cells, though a barrier oncoviral therapies have faced is a limited therapeutic response to currently delivery techniques...
December 4, 2018: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/30514297/sox30-specially-prevents-wnt-signaling-to-suppress-metastasis-and-improve-prognosis-of-lung-adenocarcinoma-patients
#12
Fei Han, Ming-Qian Zhang, Wen-Bin Liu, Lei Sun, Xiang-Lin Hao, Li Yin, Xiao Jiang, Jia Cao, Jin-Yi Liu
BACKGROUND: Different histological subtypes of non-small cell lung cancer (NSCLC) show different molecular characteristics and responses to therapeutic strategy. Identification of specific gene, clarification of its special roles and molecular mechanisms are crucial for developing new therapeutic approach for particular subtype patients. METHODS: Surgical specimens of 540 NSCLC patients were recruited. Immunohistochemistry was used to detect SOX30 expression, and correlations with clinical parameters were analyzed...
December 4, 2018: Respiratory Research
https://www.readbyqxmd.com/read/30513898/face-recognition-using-the-sr-cnn-model
#13
Yu-Xin Yang, Chang Wen, Kai Xie, Fang-Qing Wen, Guan-Qun Sheng, Xin-Gong Tang
In order to solve the problem of face recognition in complex environments being vulnerable to illumination change, object rotation, occlusion, and so on, which leads to the imprecision of target position, a face recognition algorithm with multi-feature fusion is proposed. This study presents a new robust face-matching method named SR-CNN, combining the rotation-invariant texture feature (RITF) vector, the scale-invariant feature transform (SIFT) vector, and the convolution neural network (CNN). Furthermore, a graphics processing unit (GPU) is used to parallelize the model for an optimal computational performance...
December 3, 2018: Sensors
https://www.readbyqxmd.com/read/30513633/community-views-on-what-i-want-before-i-die
#14
Deb Rawlings, Lauren Miller-Lewis, Jennifer Tieman
Few previous studies have formally examined people's wishes regarding what they want to do before they die. This study aimed to describe responses to an activity within a Massive Open Online Course (MOOC) where people considered what was important when faced with their own mortality. We asked participants to complete the following: "Before I Die, I want to…". The content of participants' responses ( n = 633) was analysed qualitatively with a coding schema developed and then applied. All authors independently coded the first 100 "Before I Die" statements, followed by a second round of coding where themes were verified and confirmed...
November 30, 2018: Behavioral Sciences
https://www.readbyqxmd.com/read/30513448/adult-student-nurses-experiences-of-encountering-perceived-child-abuse-or-neglect-during-their-community-placement-implications-for-nurse-education
#15
Julie Tweedlie, Sharon Vincent
INTRODUCTION: While child nursing students may expect to encounter child abuse and neglect and assume a safeguarding role when they qualify, those undertaking adult nursing courses may not expect to come into contact with children and may be even less likely to expect to encounter child abuse or neglect. This paper presents the findings of an interpretative phenomenological analysis (IPA) study. Students learn through experience and reflection and Mezirow's Transformational Learning Theory (TLT) was used to explain the various ways in which nine adult nursing students attempted to make sense of and learn from their experiences of encountering perceived child abuse and neglect during their community placement...
November 14, 2018: Nurse Education Today
https://www.readbyqxmd.com/read/30513084/neurobiology-of-social-reward-valuation-in-adults-with-a-history-of-anorexia-nervosa
#16
Maggie M Sweitzer, Karli K Watson, Savannah R Erwin, Amy A Winecoff, Nandini Datta, Scott Huettel, Michael L Platt, Nancy L Zucker
OBJECTIVE: Anorexia nervosa (AN) is a disorder characterized by atypical patterns of reward valuation (e.g. positive valuation of hunger). Atypical reward processing may extend into social domains. If so, such findings would be of prognostic significance as impaired social functioning predicts worse outcome. We explore neural circuits implicated in social reward processing in individuals with a history of AN who are weight-restored relative to controls and examine the effects of illness course on the experience of social value...
2018: PloS One
https://www.readbyqxmd.com/read/30513042/recognition-memory-in-marmoset-and-macaque-monkeys-a-comparison-of-active-vision
#17
Samuel U Nummela, Michael J Jutras, John T Wixted, Elizabeth A Buffalo, Cory T Miller
The core functional organization of the primate brain is remarkably conserved across the Order, but behavioral differences evident between species likely reflect derived modifications in the underlying neural processes. Here, we performed the first study to directly compare visual recognition memory in two primate species-rhesus macaques and marmoset monkeys-on the same visual preferential looking task as a first step toward identifying similarities and differences in this cognitive process across the primate phylogeny...
December 4, 2018: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/30513011/label-free-plasmonic-biosensors-for-point-of-care-diagnostics-a-review
#18
Maria Soler, Cesar S Huertas, Laura M Lechuga
Optical biosensors and particularly those based on nanoplasmonics technology have emerged in recent decades as a potential solution for disease diagnostics and therapy follow-up at the point-of-care. These biosensor platforms could overcome some of the challenges faced in conventional diagnosis techniques offering label-free assays with immediate results and employing small and user-friendly devices. Areas covered: In this review, we will provide a critical overview of the recent advances in the development of nanoplasmonic biosensors for point-of-care diagnostics...
December 4, 2018: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/30512938/mixed-valence-iron-dumortierite-fe-13-5-2-22-as-5-o-4-x-8-oh-6-and-its-intricate-topotactic-exsolution-at-mild-temperatures
#19
Olivier Mentre, Ignacio Blazquez-Alcover, Susana Garcia-Martin, Mathieu Duttine, Alain Wattiaux, Pardis Simon, Marielle Huve, Sylvie Daviero-Minaud
The mixed-valent iron arsenate hydroxide Fe13.5 2.22+ (AsO4- x )8 (OH)6 , x = 0.25, was prepared using the reaction of iron metal with arsenate in aqueous solution and autogenous pressure. Its crystal structure reveals a dumortierite-like framework with mixed-valent Fe2+/ Fe3+ in double chains creating channel walls. Remarkably, hexagonal channels consist of chains of face-sharing Fe2+ O6 octahedra, 3/4th occupied, whereas AsO4 tetrahedra occupy triangular ones with a single " up" orientation according to the polar P63 mc symmetry...
December 4, 2018: Inorganic Chemistry
https://www.readbyqxmd.com/read/30512934/design-and-enantioresolution-of-homochiral-fe-ii-pd-ii-coordination-cages-from-stereolabile-metalloligands-stereochemical-stability-and-enantioselective-separation
#20
Ya-Jun Hou, Kai Wu, Zhang-Wen Wei, Kang Li, Yu-Lin Lu, Cheng-Yi Zhu, Jing-Si Wang, Mei Pan, Ji-Jun Jiang, Guangqin Li, Cheng-Yong Su
The stereochemistry of chiral-at-metal complexes is much more abundant, albeit complicated, than chiral-at-carbon compounds, but how to make use of stereolabile metal-centers remains a formidable challenge due to highly versatile coordination geometry of metal ions and racemization/epimerization problem. We demonstrate herein a stepwise assembly of configurationally stable [Pd6 (FeL3 )8 ]28 + ( Δ/ Λ-MOCs-42) homochiral octahedral cages from unstable D3 -symmetry tris-chelate-Fe type metalloligands via strong face-directed stereochemical coupling and facile chiral-induced resolution processes based on stereodifferentiating host-guest dynamics...
December 4, 2018: Journal of the American Chemical Society
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