Alena Mazurakova, Zuzana Solarova, Lenka Koklesova, Martin Caprnda, Robert Prosecky, Artur Khakymov, Denis Baranenko, Peter Kubatka, Ladislav Mirossay, Peter Kruzliak, Peter Solar
Heat shock proteins (HSPs) represent cellular chaperones that are classified into several families, including HSP27, HSP40, HSP60, HSP70, and HSP90. The role of HSPs in the cell includes the facilitation of protein folding and maintaining protein structure. Both processes play crucial roles during stress conditions in the cell such as heat shock, degradation, and hypoxia. Moreover, HSPs are important modulators of cellular proliferation and differentiation, and are strongly associated with the molecular orchestration of carcinogenesis...
November 3, 2023: Advances in Medical Sciences