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https://www.readbyqxmd.com/read/28609729/reliability-of-pathogen-control-in-direct-potable-reuse-performance-evaluation-and-qmra-of-a-full-scale-1-mgd-advanced-treatment-train
#1
Brian M Pecson, Sarah C Triolo, Simon Olivieri, Elise C Chen, Aleksey N Pisarenko, Chao-Chun Yang, Adam Olivieri, Charles N Haas, R Shane Trussell, R Rhodes Trussell
To safely progress toward direct potable reuse (DPR), it is essential to ensure that DPR systems can provide public health protection equivalent to or greater than that of conventional drinking water sources. This study collected data over a one-year period from a full-scale DPR demonstration facility, and used both performance distribution functions (PDFs) and quantitative microbial risk assessment (QMRA) to define and evaluate the reliability of the advanced water treatment facility (AWTF). The AWTF's ability to control enterovirus, Giardia, and Cryptosporidium was characterized using online monitoring of surrogates in a treatment train consisting of ozone, biological activated carbon, microfiltration, reverse osmosis, and ultraviolet light with an advanced oxidation process...
June 6, 2017: Water Research
https://www.readbyqxmd.com/read/28593054/meibomian-gland-dysfunction-in-type-2-diabetic-patients
#2
Xiaolei Lin, Binbin Xu, Yuxi Zheng, Terry G Coursey, Yinying Zhao, Junhua Li, Yana Fu, Xuewen Chen, Yun-E Zhao
PURPOSE: To investigate meibomian gland and tear film function in patients with type 2 diabetes. METHODS: This prospective study compared changes in meibomian gland and tear film function in type 2 diabetic patients with nondiabetic patients. Meibomian gland function was evaluated by measuring lipid layer thickness (LLT), grading of meibomian gland loss, lid margin abnormalities, and expression of meibum. Tear film function was assessed by measuring tear breakup time (TBUT), the Schirmer I test, noninvasive breakup time (NIBUT), tear meniscus height (TMH), and corneal fluorescein staining...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28592418/growth-of-meibomian-gland-tissue-after-intraductal-meibomian-gland-probing-in-patients-with-obstructive-meibomian-gland-dysfunction
#3
Steven L Maskin, Whitney R Testa
PURPOSE: To investigate the impact of meibomian gland probing (MGP) on meibomian gland (MG) area from the upper lids of patients with obstructive meibomian gland dysfunction (o-MGD). METHODS: Retrospective study comparing pre-MGP/post-MGP non-contact infrared meibography results in patients with o-MGD, viewing signs of MG growth within total measurement field. RESULTS: Post-MGP meibography of 34 lids (19 patients, ≥4.5 to ≤12 months' follow-up) showed 41...
June 7, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28587370/a-novel-noninvasive-ocular-surface-analyzer-for-the-assessment-of-dry-eye-with-meibomian-gland-dysfunction
#4
Yuanyuan Qi, Chen Zhang, Shaozhen Zhao, Yue Huang, Ruibo Yang
Meibomian gland dysfunction (MGD) is a major cause of dry eye, and the purpose of the present study was to evaluate the differences between dry eye patients with MGD and controls using a novel noninvasive ocular surface analyzer. A total of 33 dry eye patients with MGD and 31 controls were enrolled in the present study. Testing included administration of the Ocular Surface Disease Index (OSDI), followed by Keratogragh 5M (Oculus, Wetzlar, Germany), measurements of the noninvasive tear film break-up times (NITBUTs), the first tear film break-up point and the morphology of meibomian gland...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28533678/effect-of-thermal-pulsation-treatment-on-tear-film-parameters-in-dry-eye-disease-patients
#5
Michelle J Kim, Sandra S Stinnett, Preeya K Gupta
PURPOSE: The goal of this study was to evaluate the effect of thermal pulsation treatment on tear film parameters, specifically osmolarity and matrix metalloproteinase-9 (MMP-9), in patients with meibomian gland dysfunction (MGD) and dry eye disease (DED). METHODS: A single-center review of 189 eyes that underwent thermal pulsation treatment was performed. Data were collected on pre and posttreatment osmolarity, MMP-9, tear break-up time (TBUT), and ocular surface disease index (OSDI) score...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28510629/fibroblast-growth-factor-receptor-2-fgfr2-is-required-for-meibomian-gland-homeostasis-in-the-adult-mouse
#6
Lixing W Reneker, Lanlan Wang, Rebecca T Irlmeier, Andrew J W Huang
Purpose: Little is known about the signaling mechanisms controlling meibomian gland (MG) homeostasis and the pathogenic processes leading to MG atrophy and dysfunction in dry eye disease (DED). We investigated the role of fibroblast growth factor receptor 2 (FGFR2) in the MG homeostasis of adult mice. Methods: A triple transgenic mouse strain (Krt14-rtTA; tetO-Cre; Fgfr2flox/flox), referred to as Fgfr2CKO mice, was generated in which the Fgfr2 gene is ablated by Cre recombinase in keratin 14 (Krt14)-expressing epithelial cells on doxycycline (Dox) induction...
May 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28502422/preimplantation-genetic-diagnosis-for-monogenic-diseases
#7
REVIEW
Vivian Chi Yan Lee, Judy F C Chow, William Shu Biu Yeung, Pak Chung Ho
Preimplantation genetic diagnosis (PGD) was first reported in 1990. Thereafter, more and more indications for PGD, including monogenic diseases (MGD) and translocations, are presently available, and the list of indications of PGD is expanding from early-onset and serious conditions to late-onset diseases. Polymerase chain reaction has been used for PGD of MGD, while newer techniques, including karyomapping and next-generation sequencing, emerge in recent decade. The limitations of various methods for PGD are discussed in this review...
April 15, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28501443/meibomian-gland-dysfunction-and-its-determinants-in-iranian-adults-a-population-based-study
#8
Hassan Hashemi, Hadith Rastad, Mohammad Hassan Emamian, Akbar Fotouhi
PURPOSE: To estimate the prevalence of Meibomian gland dysfunction (MGD) and determine the associated factors in the general population in Iran. METHODS: This cross-sectional study is based on the data from the second phase of the Shahroud Eye Cohort Study conducted in 2014. Of the 4737 participants of the second phase, data was available for 4700 people; their mean age was 55.9±6.2 years and 2768 (58.9%) were women. Diagnosis of MGD was made based on the classification of the International Workshop on MGD as judged by the examining ophthalmologist...
May 10, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28496300/prospective-evaluation-of-intense-pulsed-light-and-meibomian-gland-expression-efficacy-on-relieving-signs-and-symptoms-of-dry-eye-disease-due-to-meibomian-gland-dysfunction
#9
Steven J Dell, Ronald N Gaster, Sheila C Barbarino, Derek N Cunningham
PURPOSE: The aim of this study was to estimate the efficacy of intense pulsed light (IPL), followed by meibomian gland expression (MGX), for reducing the number and severity of signs and symptoms of dry eye disease (DED) secondary to meibomian gland dysfunction (MGD). PATIENTS AND METHODS: In a prospective study conducted in two sites, 40 subjects (80 eyes) with moderate to severe MGD were enrolled. Major inclusion criteria consisted of at least two of the following measures being compatible with DED in both eyes: tear breakup time (TBUT), meibomian gland score (MGS), corneal fluorescein staining (CFS), Standard Patient Evaluation of Eye Dryness (SPEED) questionnaire, and tear film osmolarity (TFO)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28486197/on-site-cellulase-production-and-efficient-saccharification-of-corn-stover-employing-cbh2-overexpressing-trichoderma-reesei-with-novel-induction-system
#10
Yonghao Li, Xiaoyue Zhang, Liang Xiong, Muhammad Aamer Mehmood, Xinqing Zhao, Fengwu Bai
Although on-site cellulase production offers cost-effective saccharification of lignocellulosic biomass, low enzyme titer is still a barrier for achieving robustness. In the present study, a strain of T. reesei was developed for enhanced production of cellulase via overexpression of Cellobiohydrolase II. Furthermore, optimum enzyme production was achieved using a novel inducer mixture containing synthesized glucose-sophorose (MGD) and alkali pre-treated corn stover (APCS). Within 60h, a remarkably higher cellulase productivity and activity were achieved in the fed-batch fermentation using the optimized ratio of MGD and APCS in the inducer mixture, compared to those reported using cellulosic biomass as the sole inducer...
August 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28475965/how-could-discharge-management-affect-florida-spring-fish-assemblage-structure
#11
Kirsten Work, Keneil Codner, Melissa Gibbs
Freshwater bodies are increasingly affected by reductions in water quantity and quality and by invasions of exotic species. To protect water quantity and maintain the ecological integrity of many water bodies in central Florida, a program of adopting Minimum Flows and Levels (MFLs) has begun for both lentic and lotic waters. The purpose of this study was to determine whether there were relationships between discharge and stage, water quality, and biological parameters for Volusia Blue Spring, a first magnitude spring (discharge > 380,000 m(3) day(-1) or 100 mgd) for which an MFL program was adopted in 2006...
May 2, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28458508/meibomian-gland-dysfunction-patients-with-novel-sj%C3%A3-gren-s-syndrome-biomarkers-benefit-significantly-from-a-single-vectored-thermal-pulsation-procedure-a-retrospective-analysis
#12
Alice T Epitropoulos, Krysta Goslin, Raman Bedi, Caroline A Blackie
PURPOSE: To measure the effects from a single vectored thermal pulsation treatment of the meibomian glands on dry eye signs and symptoms in patients who tested positively versus negatively for novel Sjögren's syndrome (SS) biomarkers. METHODS: The retrospective study included the deidentified data of 102 eyes of 59 patients with dry eye and meibomian gland dysfunction (MGD), who were also tested for novel biomarkers for SS and underwent a single 12-minute LipiFlow thermal pulsation procedure...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28444247/exposure-parameters-of-mammograms-with-and-without-mass-lesions-from-a-south-african-breast-care-centre
#13
Sussan N Acho, Willem P E Boonzaier, Ina F Nel
In South African breast care centres, full-field digital mammography units provide breast imaging services to symptomatic and asymptomatic women simultaneously. This study evaluated the technical exposure parameters of 800 mammograms of which 100 mammograms had obvious mass lesions in the fibroglandular tissue. The average breast compression force of mammograms with mass lesions in the fibroglandular tissue was 18.4% less than the average breast compression force of mammograms without mass lesions. The average mean glandular dose (MGD), tube potential (kVp) and compressed breast thickness (CBT) values were 2...
April 24, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28432828/quantitative-contrast-enhanced-spectral-mammography-based-on-photon-counting-detectors-a-feasibility-study
#14
Huanjun Ding, Sabee Molloi
PURPOSE: To investigate the feasibility of accurate quantification of iodine mass thickness in contrast-enhanced spectral mammography. MATERIALS AND METHODS: A computer simulation model was developed to evaluate the performance of a photon-counting spectral mammography system in the application of contrast-enhanced spectral mammography. A figure-of-merit (FOM), which was defined as the decomposed iodine signal-to-noise ratio (SNR) with respect to the square root of the mean glandular dose (MGD), was chosen to optimize the imaging parameters, in terms of beam energy, splitting energy, and pre-filtrations for breasts of various thicknesses and densities...
April 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/28424712/a-functional-approach-towards-understanding-the-role-of-the-mitochondrial-respiratory-chain-in-an-endomycorrhizal-symbiosis
#15
Louis Mercy, Eva Lucic-Mercy, Amaia Nogales, Areg Poghosyan, Carolin Schneider, Birgit Arnholdt-Schmitt
Arbuscular mycorrhizal fungi (AMF) are crucial components of fertile soils, able to provide several ecosystem services for crop production. Current economic, social and legislative contexts should drive the so-called "second green revolution" by better exploiting these beneficial microorganisms. Many challenges still need to be overcome to better understand the mycorrhizal symbiosis, among which (i) the biotrophic nature of AMF, constraining their production, while (ii) phosphate acts as a limiting factor for the optimal mycorrhizal inoculum application and effectiveness...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28419125/mammographic-compression-in-asian-women
#16
Susie Lau, Yang Faridah Abdul Aziz, Kwan Hoong Ng
OBJECTIVES: To investigate: (1) the variability of mammographic compression parameters amongst Asian women; and (2) the effects of reducing compression force on image quality and mean glandular dose (MGD) in Asian women based on phantom study. METHODS: We retrospectively collected 15818 raw digital mammograms from 3772 Asian women aged 35-80 years who underwent screening or diagnostic mammography between Jan 2012 and Dec 2014 at our center. The mammograms were processed using a volumetric breast density (VBD) measurement software (Volpara) to assess compression force, compression pressure, compressed breast thickness (CBT), breast volume, VBD and MGD against breast contact area...
2017: PloS One
https://www.readbyqxmd.com/read/28410360/estimation-of-prevalence-of-meibomian-gland-dysfunction-in-japan
#17
Shiro Amano, Kenji Inoue
PURPOSE: To estimate the prevalence of meibomian gland dysfunction (MGD) in the Japanese population using new diagnostic criteria, including lid margin abnormalities and signs of occlusion of the meibomian gland orifices as essential signs. METHODS: The participants were consecutive patients scheduled for cataract surgery at Inouye Eye Hospital. All participants were aged 50 years or older. The participants completed a symptoms questionnaire and underwent a comprehensive slit-lamp examination...
June 2017: Cornea
https://www.readbyqxmd.com/read/28384900/efficacy-of-green-tea-extract-for-treatment-of-dry-eye-and-meibomian-gland-dysfunction-a-double-blind-randomized-controlled-clinical-trial-study
#18
Mahmood Nejabat, Salehi Ali Reza, Mehdi Zadmehr, Masoud Yasemi, Zahra Sobhani
INTRODUCTION: With an incidence rate of 9%, dry eye is a common problem of the ocular surface, especially in patients more than 40-year-old. Green tea extract has anti-oxidative, anti-bacterial, anti-androgen, and immunomodulatory properties. AIM: To evaluate the efficacy of green tea extract for treatment of patients with dry eye and Meibomian Gland Dysfunction (MGD). MATERIALS AND METHODS: In a double-blind randomized controlled clinical trial, 60 patients were selected within the age range of 30 to 70 years, and divided into two groups by blocked randomization method...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28368991/ocular-surface-parameters-predicting-patient-satisfaction-after-a-single-vectored-thermal-pulsation-procedure-for-management-of-symptomatic-meibomian-gland-dysfunction
#19
Allister Gibbons, Daniel Waren, Nilufer Yesilirmak, Kendra Davis, Felipe Valenzuela, Juan C Murillo, Victor L Perez
PURPOSE: To evaluate the ocular surface parameters that could predict patient satisfaction after single application of vectored thermal pulsation (VTP). METHODS: This is a retrospective interventional case series; it included consecutive patients who underwent bilateral VTP for management of symptomatic meibomian gland dysfunction (MGD). Patients received a full ocular surface evaluation. The outcome was patient subjective improvement during the first 3-4 months after 3 follow-up visits...
June 2017: Cornea
https://www.readbyqxmd.com/read/28365118/effect-of-increasing-the-proportion-of-dietary-concentrate-on-gastrointestinal-tract-measurements-and-brush-border-enzyme-activity-in-holstein-steers
#20
P Górka, B L Schurmann, M E Walpole, A Błońska, S Li, J C Plaizier, Z M Kowalski, G B Penner
The aim of this study was to determine the time course for adaptation of the reticulo-rumen, omasum, abomasum, and small intestine in response to an abrupt increase in the proportion of grain in the diet. Adaptive responses include tissue and digesta mass, small intestinal length, and brush border enzyme activity in the duodenum, proximal jejunum, and ileum. Twenty-five Holstein steers (213 ± 23 kg; 5 to 7 mo of age) were blocked by body weight, and within block were randomly assigned to 1 of 5 treatments: the control diet (CTRL; 92% chopped grass hay and 8% mineral and vitamin supplement on a dry matter basis) or a moderate grain diet (MGD; 50% chopped grass hay, 42% rolled barley grain, and 8% mineral and vitamin supplement) that was fed for 3 (MGD3), 7 (MGD7), 14 (MGD14), or 21 d (MGD21)...
March 29, 2017: Journal of Dairy Science
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