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https://www.readbyqxmd.com/read/29656886/oscillatory-squeeze-film-analysis-of-soft-contact-lenses
#1
Éanna Mac Donnchadha, Cristina Leal, Harry Esmonde
The complex modulus of a soft contact lens affects the optical performance, fitting, on-eye movement, wettability, physiological impact and overall comfort of the lens. However, despite acknowledgement that the mechanical behaviour of contact lenses is time-dependent, the rheological characteristics of contact lenses remain under-defined. While existing studies have focussed on elasticity to describe lens behaviour, this paper proposes using oscillatory squeeze film analysis to evaluate the complex modulus...
April 13, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29643799/optical-coherence-tomography-examination-of-the-anterior-segment-in-a-case-of-corneal-perforation-and-lens-trauma-by-chestnut-burr
#2
Takashi Ono, Yosai Mori, Ryohei Nejima, Takuya Iwasaki, Shiro Amano, Kazunori Miyata
Chestnut burrs, the thorny encapsulation of chestnut fruit, can sometimes cause corneal injuries and ulceration, with poor prognoses. We report a case of corneal perforation and damaged anterior lens capsule due to a chestnut burr, using anterior segment optical coherence tomography (AS-OCT). A 67-year-old woman with a chestnut burr injury in her right eye was referred to our hospital. Her right best-corrected visual acuity (BCVA) was 0.8. Slit-lamp examination and AS-OCT showed perforation involving the endothelial layer at the center of the cornea...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29643713/modified-conjunctival-flap-as-a-primary-procedure-for-nontraumatic-acute-corneal-perforation
#3
Yi-Chen Sun, Jason P Kam, Tueng T Shen
Objective: Appropriate management of nontraumatic acute corneal perforation is always a challenge even with the many advances in surgical materials and techniques. We reported the outcomes of a case series of acute corneal perforation repair using a newly modified conjunctival flap with amniotic membrane transplant (AMT), fibrin glue, and a bandage soft contact lens (BCL). Materials and Methods: A total of 13 consecutive referral cases with nontraumatic acute corneal perforation at the University of Washington were reviewed...
January 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29611370/influence-of-sodium-hyaluronate-concentration-on-corneal-aberration-in-soft-contact-lens-wearers
#4
Jong Soo Lee, Jong Moon Park, Hyun Kyung Cho, Su Jin Kim, Hyoun Do Huh, Young Min Park
PURPOSE: This study aimed to evaluate the influence of varying concentrations of sodium hyaluronate (SH) eye drops on corneal aberrations in normal individuals wearing silicone hydrogel contact lenses. METHODS: Normal individuals wearing silicone hydrogel contact lenses were enrolled in this study. Subjects were classified into two groups depending on the concentration of the preservative-free SH used (group 1, 0.1% SH; group 2, 0.3% SH). All subjects were asked to blink five times after instillation of the SH eye drop and before the Galilei measurements...
March 13, 2018: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/29580955/intraepithelial-corneal-haemorrhage-in-a-rigid-contact-lens-wearer
#5
James Simpson, Stephen J Vincent
Intracorneal haemorrhage is a rare complication of modern contact lens wear. While a limited number of reports have described intracorneal haemorrhages (typically stromal) associated with the extended wear of soft contact lenses with limited oxygen permeability for the correction of aphakia, this case report documents the management and resolution of a significant intraepithelial corneal haemorrhage associated with long-term rigid contact lens wear for keratoconus and high myopia.
March 23, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29561497/visual-acuity-and-over-refraction-in-myopic-children-fitted-with-soft-multifocal-contact-lenses
#6
Krystal L Schulle, David A Berntsen, Loraine T Sinnott, Katherine M Bickle, Anita T Gostovic, Gilbert E Pierce, Lisa A Jones-Jordan, Donald O Mutti, Jeffrey J Walline
SIGNIFICANCE: Practitioners fitting contact lenses for myopia control frequently question whether a myopic child can achieve good vision with a high-add multifocal. We demonstrate that visual acuity is not different than spectacles with a commercially available, center-distance soft multifocal contact lens (MFCL) (Biofinity Multifocal "D"; +2.50 D add). PURPOSE: To determine the spherical over-refraction (SOR) necessary to obtain best-corrected visual acuity (BCVA) when fitting myopic children with a center-distance soft MFCL...
March 21, 2018: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29471697/first-report-of-acanthamoeba-genotype-t8-human-keratitis
#7
Erika Orosz, Nóra Szentmáry, Huba J Kiss, Ágnes Farkas, István Kucsera, Zoltán Zsolt Nagy
Acanthamoeba has a worldwide distribution in the environment and it is capable of causing a painful sight-threatening disease of the cornea designated as Acanthamoeba keratitis (AK). Nowadays, the cases of AK have surged all over the world along with its disease burden due to increasing use of contact lenses used not only for optical correction but also for cosmetic purposes. In our present work, epithelial abrasion of a 27-year-old female soft contact lens wearer with keratitis was examined. Genotype identification was carried out with a real-time fluorescence resonance energy transfer polymerase chain reaction (PCR) assay based on sequence analysis of the 18S rRNA gene...
February 23, 2018: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/29454097/improving-sustained-drug-delivery-from-ophthalmic-lens-materials-through-the-control-of-temperature-and-time-of-loading
#8
Ana Topete, Andreia S Oliveira, A Fernandes, T G Nunes, A P Serro, B Saramago
Although the possibility of using drug-loaded ophthalmic lens to promote sustained drug release has been thoroughly pursued, there are still problems to be solved associated to the different alternatives. In this work, we went back to the traditional method of drug loading by soaking in the drug solution and tried to optimize the release profiles by changing the temperature and the time of loading. Two materials commercially available under the names of CI26Y and Definitive 50 were chosen. CI26Y is used for intraocular lenses (IOLs) and Definitive 50 for soft contact lenses (SCLs)...
February 14, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29401882/optical-design-of-soft-multifocal-contact-lens-with-uniform-optical-power-in-center-distance-zone-with-optimized-nurbs
#9
Lien T Vu, Chao-Chang A Chen, Chia-Wei Yu
This study aims to develop a new optical design method of soft multifocal contact lens (CLs) to obtain uniform optical power in large center-distance zone with optimized Non-Uniform Rational B-spline (NURBS). For the anterior surface profiles of CLs, the NURBS design curves are optimized to match given optical power distributions. Then, the NURBS in the center-distance zones are fitted in the corresponding spherical/aspheric curves for both data points and their centers of curvature to achieve the uniform power...
February 5, 2018: Optics Express
https://www.readbyqxmd.com/read/29398904/a-single-vectored-thermal-pulsation-treatment-for-meibomian-gland-dysfunction-increases-mean-comfortable-contact-lens-wearing-time-by-approximately-4-hours-per-day
#10
Caroline A Blackie, Christy A Coleman, Kelly K Nichols, Lyndon Jones, Peter Q Chen, Ron Melton, David L Kading, Leslie E O'Dell, Sruthi Srinivasan
Purpose: To evaluate the effect of a single vectored thermal pulsation (VTP) treatment in contact lens wearers with meibomian gland dysfunction (MGD) and dry eye symptoms. Methods: The prospective, nonsignificant risk, open-label, randomized, multi-center clinical trial included 55 soft contact lens (SCL) wearers with MGD and evaporative dry eye. Subjects were randomized to the single VTP treatment group or an untreated control. The controls received a crossover VTP treatment at 3 months (crossover treatment group)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29392323/association-between-ocular-surface-temperature-and-tear-film-stability-in-soft-contact-lens-wearers
#11
Takashi Itokawa, Yukinobu Okajima, Takashi Suzuki, Koji Kakisu, Hiroko Iwashita, Yoshitaka Murakami, Yuichi Hori
Purpose: To investigate the correlation between the changes in the ocular surface temperature (OST) and tear film stability over soft contact lenses (SCLs). Methods: We enrolled 20 eyes of 20 normal SCL wearers (20 men; 24.4 ± 4.1 years). We used four different daily disposable SCLs: one silicone hydrogel lens (delefilcon A) and three hydrogel lenses (etafilcon A with polyvinylpyrrolidone [PVP], etafilcon A, and polymacon). OST was measured every second during 10 seconds without blinking...
February 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29391575/the-effect-of-the-timing-of-the-cessation-of-contact-lens-use-on-the-results-of-biometry
#12
Colin Goudie, Andrew Tatham, Rhys Davies, Alison Sifton, Mark Wright
BACKGROUND: Current guidelines vary regarding when to remove contact lenses prior to performing biometry, and there is no clear evidence behind these guidelines. This study aimed to determine the effect of soft contact lens wear on biometric measurements by examining the change in predicted lens power for emmetropia at several time points following removal of soft contact lenses. METHODS: A prospective, controlled study of healthy soft contact lens wearers. Biometry was performed immediately after removing contact lenses and then after 2, 4 and 7 days of no contact lens use...
February 2, 2018: Eye
https://www.readbyqxmd.com/read/29387797/soft-smart-contact-lenses-with-integrations-of-wireless-circuits-glucose-sensors-and-displays
#13
Jihun Park, Joohee Kim, So-Yun Kim, Woon Hyung Cheong, Jiuk Jang, Young-Geun Park, Kyungmin Na, Yun-Tae Kim, Jun Hyuk Heo, Chang Young Lee, Jung Heon Lee, Franklin Bien, Jang-Ung Park
Recent advances in wearable electronics combined with wireless communications are essential to the realization of medical applications through health monitoring technologies. For example, a smart contact lens, which is capable of monitoring the physiological information of the eye and tear fluid, could provide real-time, noninvasive medical diagnostics. However, previous reports concerning the smart contact lens have indicated that opaque and brittle components have been used to enable the operation of the electronic device, and this could block the user's vision and potentially damage the eye...
January 2018: Science Advances
https://www.readbyqxmd.com/read/29369227/silicone-hydrogel-and-rigid-gas-permeable-scleral-lens-tear-exchange
#14
Jerry R Paugh, Elaine Chen, Colton Heinrich, Heidi Miller, Tiffany Gates, Andrew Loc Nguyen, Timothy Edrington, Barry A Weissman
OBJECTIVES: To quantify tear elimination rate (ER) underneath silicone hydrogel (Si-Hy) and scleral gas permeable (GP) contact lenses (CLs). METHODS: Subjects successfully using either well-fitting soft Si-Hy CLs or scleral GP CLs were recruited. Most scleral GP CL wearers had irregular corneas (e.g., keratoconus). An objective fluorometer measured decay of fluorescein isothiocyanate dextran dye signal (70 kD MW) from which the tear ER in %/min was calculated. For GP scleral lenses, the ER was determined for both the initial settling period and the 30- to 60-min period, and without lenses...
January 22, 2018: Eye & Contact Lens
https://www.readbyqxmd.com/read/29364947/the-berkeley-dry-eye-flow-chart-a-fast-functional-screening-instrument-for-contact-lens-induced-dryness
#15
Andrew D Graham, Erika L Lundgrin, Meng C Lin
PURPOSE: In this article, we introduce a novel flow chart-based screening tool for the categorization of contact lens-induced dryness (CLIDE) and its impact on daily visual activities: the Berkeley Dry Eye Flow Chart (DEFC). METHODS: One hundred thirty (130) experienced soft contact lens wearers discontinued lens wear for 24 hrs, passed a baseline screening and eye health examination, completed the Ocular Surface Disease Index (OSDI) then were dispensed fresh pairs of their habitual lenses...
2018: PloS One
https://www.readbyqxmd.com/read/29332157/acanthamoeba-keratitis-in-porto-alegre-southern-brazil-28-cases-and-risk-factors
#16
Denise Leal Dos Santos, Sergio Kwitko, Diane Ruschel Marinho, Bruno Schneider de Araújo, Claudete Inês Locatelli, Marilise Brittes Rott
The increasing use of contact lenses worldwide has led to an increase in cases of Acanthamoeba keratitis, which are often associated with inappropriate cleaning of contact lenses and lens cases. This study aimed to retrospectively review 28 cases of Acanthamoeba keratitis in Porto Alegre (southern Brazil) and identify the risk factors and clinical outcomes of affected patients. Most patients had higher education (66.6%), all were users of contact lenses, mostly women (67.9%). Most patients were soft contact lens wearers (66...
March 2018: Parasitology Research
https://www.readbyqxmd.com/read/29286836/are-contact-lens-discomfort-or-soft-contact-lens-material-properties-associated-with-alterations-in-the-corneal-sub-basal-nerve-plexus
#17
Alberto López-De La Rosa, Cristina Arroyo-Del Arroyo, Pilar Cañadas, Alberto López-Miguel, Margarita Calonge, Amalia Enríquez-De-Salamanca, María J González-García
PURPOSE: To study whether contact lens (CL) discomfort and some properties of soft CL materials are associated with alterations in the nerve fibers morphology and density of dendritic cells of the corneal sub-basal nerve plexus. MATERIALS AND METHODS: Forty soft CL wearers and 20 non-CL wearers were included. The Contact Lens Dry Eye Questionnaire-short form was administered to divide CL wearers based on their symptoms (20 symptomatic and 20 asymptomatic CL wearers were included)...
April 2018: Current Eye Research
https://www.readbyqxmd.com/read/29258836/fitting-success-for-three-multifocal-designs-multicentre-randomised-trial
#18
Emilia Novillo-Díaz, César Villa-Collar, Mónica Narváez-Peña, José Luis R Martín
PURPOSE: To determine if the discontinuation of commercially-available simultaneous vision Multifocal Soft Contact Lenses is independent from the multifocal design. To determine causes for discontinuation and psychosocial factors involved. METHODS: Multicentre single-blinded randomised controlled trial with external blinded evaluation for a three months follow-up period for three intervention groups. 150 single-vision soft wearers were randomly assigned a spherical near centred lens (S-CN), distance centred lens (CD) or aspherical near centred lens (A-CN)...
December 16, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29248314/the-effect-of-rebamipide-ophthalmic-suspension-on-ocular-surface-mucins-in-soft-contact-lens-wearers
#19
Chika Shigeyasu, Masakazu Yamada, Yoko Akune, Masaki Fukui
PURPOSE: To evaluate the changes in ocular surface mucins with 2%rebamipide ophthalmic suspension treatment in soft contact lens (SCL) wearers. Rebamipide suspension is a mucin secretagogue approved for the treatment of dry eye syndrome in Japan. In this study, the fluorescence intensity of wheat germ agglutinin conjugate of fluorescein (F-WGA) was used as a marker of membrane-associated mucins, and sialic acid concentration in tear fluids as a marker of secreted mucins. METHODS: Thirty-two eyes of 16 SCL wearers with discomfort were treated with rebamipide suspension at a dose of one drop in each eye four times daily for two weeks...
December 13, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29221708/daily-versus-monthly-disposable-contact-lens-which-is-better-for-ocular-surface-physiology-and-comfort
#20
Kishor Sapkota, Sandra Franco, Madalena Lira
PURPOSE: To investigate the effect of soft contact lenses (SCL) wearing modality and lens materials on the changes in conjunctival bulbar and limbal redness and conjunctival and corneal staining after two months of SCL wear. Comfort level was also analyzed. METHODS: In this longitudinal clinical trial, forty-seven neophyte myopic subjects were fitted with a monthly disposable lens (lotrafilcon-B or comfilcon-A or balafilcon-A) in one eye and a daily disposable lens (nelfilcon-A or stenofilcon-A or nesofilcon-A) in the other eye, randomly selected...
December 5, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
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