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https://www.readbyqxmd.com/read/29401882/optical-design-of-soft-multifocal-contact-lens-with-uniform-optical-power-in-center-distance-zone-with-optimized-nurbs
#1
Lien T Vu, Chao-Chang A Chen, Chia-Wei Yu
This study aims to develop a new optical design method of soft multifocal contact lens (CLs) to obtain uniform optical power in large center-distance zone with optimized Non-Uniform Rational B-spline (NURBS). For the anterior surface profiles of CLs, the NURBS design curves are optimized to match given optical power distributions. Then, the NURBS in the center-distance zones are fitted in the corresponding spherical/aspheric curves for both data points and their centers of curvature to achieve the uniform power...
February 5, 2018: Optics Express
https://www.readbyqxmd.com/read/29398904/a-single-vectored-thermal-pulsation-treatment-for-meibomian-gland-dysfunction-increases-mean-comfortable-contact-lens-wearing-time-by-approximately-4-hours-per-day
#2
Caroline A Blackie, Christy A Coleman, Kelly K Nichols, Lyndon Jones, Peter Q Chen, Ron Melton, David L Kading, Leslie E O'Dell, Sruthi Srinivasan
Purpose: To evaluate the effect of a single vectored thermal pulsation (VTP) treatment in contact lens wearers with meibomian gland dysfunction (MGD) and dry eye symptoms. Methods: The prospective, nonsignificant risk, open-label, randomized, multi-center clinical trial included 55 soft contact lens (SCL) wearers with MGD and evaporative dry eye. Subjects were randomized to the single VTP treatment group or an untreated control. The controls received a crossover VTP treatment at 3 months (crossover treatment group)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29392323/association-between-ocular-surface-temperature-and-tear-film-stability-in-soft-contact-lens-wearers
#3
Takashi Itokawa, Yukinobu Okajima, Takashi Suzuki, Koji Kakisu, Hiroko Iwashita, Yoshitaka Murakami, Yuichi Hori
Purpose: To investigate the correlation between the changes in the ocular surface temperature (OST) and tear film stability over soft contact lenses (SCLs). Methods: We enrolled 20 eyes of 20 normal SCL wearers (20 men; 24.4 ± 4.1 years). We used four different daily disposable SCLs: one silicone hydrogel lens (delefilcon A) and three hydrogel lenses (etafilcon A with polyvinylpyrrolidone [PVP], etafilcon A, and polymacon). OST was measured every second during 10 seconds without blinking...
February 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29391575/the-effect-of-the-timing-of-the-cessation-of-contact-lens-use-on-the-results-of-biometry
#4
Colin Goudie, Andrew Tatham, Rhys Davies, Alison Sifton, Mark Wright
BACKGROUND: Current guidelines vary regarding when to remove contact lenses prior to performing biometry, and there is no clear evidence behind these guidelines. This study aimed to determine the effect of soft contact lens wear on biometric measurements by examining the change in predicted lens power for emmetropia at several time points following removal of soft contact lenses. METHODS: A prospective, controlled study of healthy soft contact lens wearers. Biometry was performed immediately after removing contact lenses and then after 2, 4 and 7 days of no contact lens use...
February 2, 2018: Eye
https://www.readbyqxmd.com/read/29387797/soft-smart-contact-lenses-with-integrations-of-wireless-circuits-glucose-sensors-and-displays
#5
Jihun Park, Joohee Kim, So-Yun Kim, Woon Hyung Cheong, Jiuk Jang, Young-Geun Park, Kyungmin Na, Yun-Tae Kim, Jun Hyuk Heo, Chang Young Lee, Jung Heon Lee, Franklin Bien, Jang-Ung Park
Recent advances in wearable electronics combined with wireless communications are essential to the realization of medical applications through health monitoring technologies. For example, a smart contact lens, which is capable of monitoring the physiological information of the eye and tear fluid, could provide real-time, noninvasive medical diagnostics. However, previous reports concerning the smart contact lens have indicated that opaque and brittle components have been used to enable the operation of the electronic device, and this could block the user's vision and potentially damage the eye...
January 2018: Science Advances
https://www.readbyqxmd.com/read/29369227/silicone-hydrogel-and-rigid-gas-permeable-scleral-lens-tear-exchange
#6
Jerry R Paugh, Elaine Chen, Colton Heinrich, Heidi Miller, Tiffany Gates, Andrew Loc Nguyen, Timothy Edrington, Barry A Weissman
OBJECTIVES: To quantify tear elimination rate (ER) underneath silicone hydrogel (Si-Hy) and scleral gas permeable (GP) contact lenses (CLs). METHODS: Subjects successfully using either well-fitting soft Si-Hy CLs or scleral GP CLs were recruited. Most scleral GP CL wearers had irregular corneas (e.g., keratoconus). An objective fluorometer measured decay of fluorescein isothiocyanate dextran dye signal (70 kD MW) from which the tear ER in %/min was calculated. For GP scleral lenses, the ER was determined for both the initial settling period and the 30- to 60-min period, and without lenses...
January 22, 2018: Eye & Contact Lens
https://www.readbyqxmd.com/read/29364947/the-berkeley-dry-eye-flow-chart-a-fast-functional-screening-instrument-for-contact-lens-induced-dryness
#7
Andrew D Graham, Erika L Lundgrin, Meng C Lin
PURPOSE: In this article, we introduce a novel flow chart-based screening tool for the categorization of contact lens-induced dryness (CLIDE) and its impact on daily visual activities: the Berkeley Dry Eye Flow Chart (DEFC). METHODS: One hundred thirty (130) experienced soft contact lens wearers discontinued lens wear for 24 hrs, passed a baseline screening and eye health examination, completed the Ocular Surface Disease Index (OSDI) then were dispensed fresh pairs of their habitual lenses...
2018: PloS One
https://www.readbyqxmd.com/read/29332157/acanthamoeba-keratitis-in-porto-alegre-southern-brazil-28-cases-and-risk-factors
#8
Denise Leal Dos Santos, Sergio Kwitko, Diane Ruschel Marinho, Bruno Schneider de Araújo, Claudete Inês Locatelli, Marilise Brittes Rott
The increasing use of contact lenses worldwide has led to an increase in cases of Acanthamoeba keratitis, which are often associated with inappropriate cleaning of contact lenses and lens cases. This study aimed to retrospectively review 28 cases of Acanthamoeba keratitis in Porto Alegre (southern Brazil) and identify the risk factors and clinical outcomes of affected patients. Most patients had higher education (66.6%), all were users of contact lenses, mostly women (67.9%). Most patients were soft contact lens wearers (66...
January 14, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29286836/are-contact-lens-discomfort-or-soft-contact-lens-material-properties-associated-with-alterations-in-the-corneal-sub-basal-nerve-plexus
#9
Alberto López-De La Rosa, Cristina Arroyo-Del Arroyo, Pilar Cañadas, Alberto López-Miguel, Margarita Calonge, Amalia Enríquez-De-Salamanca, María J González-García
PURPOSE: To study whether contact lens (CL) discomfort and some properties of soft CL materials are associated with alterations in the nerve fibers morphology and density of dendritic cells of the corneal sub-basal nerve plexus. MATERIALS AND METHODS: Forty soft CL wearers and 20 non-CL wearers were included. The Contact Lens Dry Eye Questionnaire-short form was administered to divide CL wearers based on their symptoms (20 symptomatic and 20 asymptomatic CL wearers were included)...
December 29, 2017: Current Eye Research
https://www.readbyqxmd.com/read/29258836/fitting-success-for-three-multifocal-designs-multicentre-randomised-trial
#10
Emilia Novillo-Díaz, César Villa-Collar, Mónica Narváez-Peña, José Luis R Martín
PURPOSE: To determine if the discontinuation of commercially-available simultaneous vision Multifocal Soft Contact Lenses is independent from the multifocal design. To determine causes for discontinuation and psychosocial factors involved. METHODS: Multicentre single-blinded randomised controlled trial with external blinded evaluation for a three months follow-up period for three intervention groups. 150 single-vision soft wearers were randomly assigned a spherical near centred lens (S-CN), distance centred lens (CD) or aspherical near centred lens (A-CN)...
December 16, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29248314/the-effect-of-rebamipide-ophthalmic-suspension-on-ocular-surface-mucins-in-soft-contact-lens-wearers
#11
Chika Shigeyasu, Masakazu Yamada, Yoko Akune, Masaki Fukui
PURPOSE: To evaluate the changes in ocular surface mucins with 2%rebamipide ophthalmic suspension treatment in soft contact lens (SCL) wearers. Rebamipide suspension is a mucin secretagogue approved for the treatment of dry eye syndrome in Japan. In this study, the fluorescence intensity of wheat germ agglutinin conjugate of fluorescein (F-WGA) was used as a marker of membrane-associated mucins, and sialic acid concentration in tear fluids as a marker of secreted mucins. METHODS: Thirty-two eyes of 16 SCL wearers with discomfort were treated with rebamipide suspension at a dose of one drop in each eye four times daily for two weeks...
December 13, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29221708/daily-versus-monthly-disposable-contact-lens-which-is-better-for-ocular-surface-physiology-and-comfort
#12
Kishor Sapkota, Sandra Franco, Madalena Lira
PURPOSE: To investigate the effect of soft contact lenses (SCL) wearing modality and lens materials on the changes in conjunctival bulbar and limbal redness and conjunctival and corneal staining after two months of SCL wear. Comfort level was also analyzed. METHODS: In this longitudinal clinical trial, forty-seven neophyte myopic subjects were fitted with a monthly disposable lens (lotrafilcon-B or comfilcon-A or balafilcon-A) in one eye and a daily disposable lens (nelfilcon-A or stenofilcon-A or nesofilcon-A) in the other eye, randomly selected...
December 5, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29219898/orthokeratology-and-contact-lens-quality-of-life-questionnaire-ocl-qol
#13
Colm McAlinden, Michael Lipson
OBJECTIVES: To develop a quality of life (QoL) instrument for patients fitted with Orthokeratology (OrthoK) and other modalities of contact lenses. METHODS: A 45-item pilot questionnaire was developed from an extensive literature review, focus groups, and interviews. Subsequently, 234 participants fitted with contact lenses (OrthoK, soft lenses, and gas permeable lenses) or spectacles completed the pilot questionnaire. Rasch analysis was used to assess the psychometric properties in terms of person separation, item fit statistics, category threshold ordering, differential item functioning (DIF), and targeting...
December 5, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29217022/focal-limbal-stem-cell-deficiency-associated-with-soft-contact-lens-wear
#14
Karolien Termote, Steven Schendel, Gregory Moloney, Simon P Holland, Alex P Lange
OBJECTIVE: The aim of this study is to summarize the clinical characteristics of patients with contact lens-associated focal limbal stem cell deficiency (FLSCD) from a tertiary corneal referral centre. DESIGN: Retrospective, observational case series in a tertiary care centre. METHODS: Patients with contact lens-associated FLCSD were identified in our database. Clinical data were retrieved by chart review. A questionnaire asking for contact lens brand, type, cleaning solution, and duration of contact lens wear was sent to the patients with telephone follow-up...
December 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/29213204/in-vitro-release-of-two-anti-muscarinic-drugs-from-soft-contact-lenses
#15
Alex Hui, Magdalena Bajgrowicz-Cieslak, Chau-Minh Phan, Lyndon Jones
The purpose of this study was to investigate the release of the anti-myopia drugs atropine sulfate and pirenzepine dihydrochloride from commercially available soft contact lenses. Standard ultraviolet (UV) absorbance-concentration curves were generated for atropine and pirenzepine. Ten commercially available contact lenses, including four multifocal lenses, were loaded by soaking in atropine or pirenzepine solutions at two different concentrations (10 mg/mL and 1 mg/mL). The release of the drugs into phosphate-buffered saline was determined over the course of 24 hours at 34°C using UV absorbance...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29204707/ocular-surface-and-tear-film-status-among-contact-lens-wearers-and-non-wearers-who-use-vdt-at-work-comparing-three-different-lens-types
#16
Ana Tauste, Elena Ronda, Valborg Baste, Magne Bråtveit, Bente E Moen, María-Del-Mar Seguí Crespo
PURPOSE: To analyze differences in the ocular surface appearance and tear film status of contact lens wearers and non-wearers in a group of visual display terminals (VDT) workers and additionally to assess differences between lens materials. METHODS: Cross-sectional study of 236 office workers, of whom 92 were contact lens wearers. Workers provided information on their contact lenses (conventional hydrogel, silicone hydrogel or rigid gas permeable lenses) and exposure to VDT at work...
December 4, 2017: International Archives of Occupational and Environmental Health
https://www.readbyqxmd.com/read/29162075/the-antibiofilm-efficacy-of-nitric-oxide-on-soft-contact-lenses
#17
Dong Ju Kim, Joo-Hee Park, Marth Kim, Choul Yong Park
BACKGROUND: To investigate the antibiofilm efficacy of nitric oxide (NO) on soft contact lenses. METHODS: Nitrite (NO precursor) release from various concentrations (0-1000 μM) of sodium nitrite (NaNO2, NO donor) was measured by Griess Assay. Cell viability assay was performed using human corneal epithelial cell under various concentration (0-1000 μM) of NaNO2. Biofilm formation on soft contact lenses was achieved by adding Staphylococcus aureus or Pseudomonas aeruginosa to the culture media...
November 21, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29135738/efficacy-of-rebamipide-instillation-for-contact-lens-discomfort-with-dry-eye
#18
Tsutomu Igarashi, Maika Kobayashi, Chiemi Yaguchi, Chiaki Fujimoto, Hisaharu Suzuki, Hiroshi Takahashi
OBJECTIVE: To examine the effects of rebamipide ophthalmic solution on the symptoms, signs, and cytokine concentrations in tear fluid among soft contact lens (SCL) wearers with Dry eye disease (DED). METHODS: From November 2015 to June 2017, this open-label, single-arm study examined 40 eyes of 20 SCL wearers with DED who had been using daily disposable SCLs for >3 months (mean age, 30.0±8.33 years; range, 20-47 years). Signs, symptoms, and cytokine concentrations were assessed before and 4 weeks after starting 2% rebamipide ophthalmic solution 4 times/day...
November 10, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29119310/on-the-regional-variability-of-averaged-cell-area-estimates-for-the-human-corneal-endothelium-in-relation-to-the-extent-of-polymegethism
#19
M J Doughty
PURPOSE: To assess variability in the coefficient of variation (COV) in cell area estimates when using different numbers of cells for endothelial morphometry. METHODS: Using non-contact specular microscopy images of the corneal endothelium, 4 sets of 20 cases were selected that included 200 cells and had overall (global) COV values of less than 30 (group 1), 31-40 (group 2), 41-50 (group 3) and over 50% (group 4). Subjects could be normal, or had ophthalmic disease (such as diabetes), a history of rigid or soft contact lens wear or were assessed after cataract surgery...
November 7, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/29116965/mechanical-properties-of-contact-lens-materials
#20
Eon Kim, Mou Saha, Klaus Ehrmann
OBJECTIVES: To evaluate the mechanical properties of commonly available soft contact lens materials and compare results using custom-built MicroTensometer. METHODS: The Young modulus, parameters for stress relaxation, and toughness of 18 types of single vision soft contact lenses were measured using custom-built MicroTensometer. Five lenses of each type were soaked in standard phosphate buffered saline and measured at a temperature of 35°C. Each lens was flattened and sliced into a rectangular strip sample using two parallel blades...
November 7, 2017: Eye & Contact Lens
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