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https://www.readbyqxmd.com/read/28410356/water-exposure-is-a-common-risk-behavior-among-soft-and-gas-permeable-contact-lens-wearers
#1
Aaron B Zimmerman, Kathryn Richdale, Gladys Lynn Mitchell, Beth T Kinoshita, Dawn Y Lam, Heidi Wagner, Luigina Sorbara, Robin L Chalmers, Sarah A Collier, Jennifer R Cope, Maya M Rao, Michael J Beach, Jonathan S Yoder
PURPOSE: To understand soft contact lens (SCL) and gas-permeable (GP) lens wearers' behaviors and knowledge regarding exposure of lenses to water. METHODS: The Contact Lens Risk Survey (CLRS) and health behavior questions were completed online by a convenience sample of 1056 SCL and 85 GP lens wearers aged 20 to 76 years. Participants were asked about exposing their lenses to water and their understanding of risks associated with these behaviors. Chi-square analyses examined relationships between patient behaviors and perceptions...
April 13, 2017: Cornea
https://www.readbyqxmd.com/read/28359825/bilateral-simultaneous-infective-keratitis
#2
Lai Hiu On Annie, Manotosh Ray
AIM: To analyze the demographics, risk factors, clinical and microbiological characteristics of cases of bilateral simultaneous infective keratitis. METHODS: In this retrospective case series, patients with clinical evidence of bilateral simultaneous infective keratitis were identified from January 1, 2011 to August 31, 2016. Demographics, risk factors, clinical and microbiological characteristics, and treatment outcomes were analyzed. RESULTS: Five patients (ten eyes) with bilateral simultaneous infective keratitis were identified...
March 27, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28328726/clinical-outcomes-and-contact-lens-case-contamination-using-a-povidone-iodine-disinfection-system
#3
Jacqueline Tan, Ananya Datta, Katherine Wong, Mark D P Willcox, Ajay K Vijay
OBJECTIVE: To assess the incidence of adverse events during the use of a povidone-iodine disinfecting solution (cleadew) and the microbial contamination in contact lens cases. METHODS: A prospective, single-center, open-label, controlled study evaluating the use of cleadew cleaning and disinfecting system in existing daily wear soft contact lens wearers over a 3-month period was conducted. Ocular signs and symptoms during lens wear were assessed at baseline and after 1 and 3 months of using cleadew...
March 21, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28317680/risk-for-microbial-keratitis-comparative-metaanalysis-of-contact-lens-wearers-and-post-laser-in-situ-keratomileusis-patients
#4
Jordan Masters, Mehmet Kocak, Aaron Waite
PURPOSE: To compare the risk for microbial keratitis in contact lens wearers stratified by wear schedule with the risk after laser in situ keratomileusis (LASIK). SETTING: Hamilton Eye Institute and Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, Tennessee, USA. DESIGN: Comparative metaanalysis and literature review. METHODS: An extensive literature search was performed in the PubMed database between December 2014 and July 2015...
January 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28303823/bacterial-and-fungal-biofilm-formation-on-contact-lenses-and-their-susceptibility-to-lens-care-solutions
#5
Siddharth Kackar, Ethel Suman, M Shashidhar Kotian
BACKGROUND: Microbial biofilm formation on contact lenses and lens storage cases may be a risk factor for contact lens-associated corneal infections. Various types of contact lens care solutions are used to reduce microbial growths on lenses. OBJECTIVES: The present study aimed at comparing the growths of biofilms on the different contact lenses and lens cases. The study also aimed at determining the effect of lens care solutions and bacteriophage on these biofilms...
January 2017: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28280635/influence-of-tear-protein-deposition-on-the-oxygen-permeability-of-soft-contact-lenses
#6
Se Eun Lee, So Ra Kim, Mijung Park
Purpose. To investigate the effect of tear protein deposition on the change in oxygen permeability (Dk) of soft contact lenses (SCL). Methods. Three hydrogel lenses (polymacon, nelfilcon A, and etafilcon A) and two silicon hydrogel lenses (lotrafilcon A and balafilcon A) were investigated. Etafilcon A lenses were incubated in artificial tear solution for 1, 6, 12, and 48 h, whereas the other SCL were incubated for 1, 3, 7, and 14 days. Oxygen permeability was measured using the polarographic method, and lenses were stacked in four layers to correct the boundary effect...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28279746/a-link-between-tear-breakup-and-symptoms-of-ocular-irritation
#7
Jun Zhang, Carolyn G Begley, Ping Situ, Trefford Simpson, Haixia Liu
PURPOSE: We used the presence or absence of a soft contact lens (CL) as a barrier to test the hypothesis that tear breakup (TBU) presents a direct noxious stimulus to the ocular surface. METHODS: Ten subjects kept one eye open as long as possible, termed sustained tear exposure (STARE), for 10 consecutive trials while discomfort was monitored with and without a CL in place. The area of TBU was quantified in each frame. Discomfort was measured during and after each STARE trial and symptoms of ocular irritation were assessed before and after all testing...
March 6, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28251809/novel-anti-biofouling-soft-contact-lens-l-cysteine-conjugated-amphiphilic-conetworks-via-raft-and-thiol-ene-click-chemistry
#8
Chengfeng Zhang, Ziyuan Liu, Haiye Wang, Xiaofeng Feng, Chunju He
A unique l-cysteine conjugated antifouling amphiphilic conetwork (APCN) is synthesized through end-crosslinking of well-defined triblock copolymers poly(allyl methacrylate)-b-poly(ethylene glycol)-b-poly(allyl methacrylate) via a combination of reversible addition-fragmentation chain transfer (RAFT) polymerization and thiol-ene "click" chemistry. The synthesized poly(ethylene glycol) macro-RAFT agent initiates the polymerization of allyl methacrylate in a controlled manner. The vinyl pendant groups of the precursor partially conjugate with l-cysteine and the rest fully crosslink with mercaptopropyl-containing siloxane via thiol-ene click chemistry under UV irradiation into APCNs, which show distinguished properties, that is, excellent biocompatibility, more than 39...
March 2, 2017: Macromolecular Bioscience
https://www.readbyqxmd.com/read/28241309/a-rabbit-model-of-acanthamoeba-keratitis-use-of-infected-soft-contact-lenses-after-corneal-epithelium-debridement-with-a-diamond-burr
#9
Ángel Ortillés, Pilar Goñi, Encarnación Rubio, Marta Sierra, Ekaterina Gámez, María T Fernández, María Benito, José Á Cristóbal, Begoña Calvo
Purpose: To develop a rabbit model of Acanthamoeba keratitis (AK) as the best method to reproduce the natural course of this disease. Methods: To induce AK, infected contact lenses (1000 amoebae/mm2, 90% trophozoites) were placed over the previously debrided corneal surface, in combination with a temporary tarsorrhaphy. Environmental and clinical strains of Acanthamoeba spp. (genotype T4) were used. Three groups (1L, n = 32; 2L-21d, n = 5; 2L-3d, n = 23) were established according to the number of contact lenses used (1L, 1 lens; 2L-21d and 2L-3d, 2 lenses) and the placement day of these (1L, day 1; 2L-21d, days 1 and 21; 2L-3d, days 1 and 3)...
February 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28225372/spherical-soft-contact-lens-designs-and-peripheral-defocus-in-myopic-eyes
#10
Kelly E Moore, Julia S Benoit, David A Berntsen
PURPOSE: Peripheral retinal defocus has been implicated in myopia progression. The effect of commercially available spherical soft contact lenses (SCLs) on peripheral defocus of adult myopic eyes was investigated. METHODS: Twenty-five young adults with spherical equivalent (SE) refractions between -0.50D and -6.00D were enrolled. Cycloplegic autorefraction (right eye) was measured centrally and ±20°, ±30°, and ±40° from the line of sight along the horizontal meridian using an autorefractor...
March 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28218002/biofilm-formation-of-achromobacter-xylosoxidans-on-contact-lens
#11
Neda Konstantinović, Ivana Ćirković, Slobodanka Đukić, Vesna Marić, Dragana D Božić
Achromobacter spp. may contaminate lenses, lens cases, and contact lens solutions and cause ocular infections. The aim of this study was to investigate the possibility of isolated strain of Achromobacter xylosoxidans to form biofilm on the surface of soft contact lenses (CL), to quantify the production of the formed biofilm, and compare it with the reference strains (Pseudomonas aeruginosa, Staphylococcus aureus, and Haemophilus influenzae). Bacterial strain isolated from one contact lens case was identified as A...
February 20, 2017: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/28215499/near-binocular-visual-function-in-young-adult-orthokeratology-versus-soft-contact-lens-wearers
#12
Kate Gifford, Paul Gifford, Peter L Hendicott, Katrina L Schmid
PURPOSE: To compare near point binocular vision function of young adult myopes wearing orthokeratology (OK) lenses to matched single vision soft disposable contact lens (SCL) wearers. METHODS: A retrospective clinical record analysis of all OK wearers (18-30 years) presenting over an 18 month period was undertaken. Data was extracted for 17 OK wearers, with 17 SCL wearers matched for age, refractive error and duration of contact lens wear. Binocular vision data included horizontal phoria (phoria), horizontal base-in (BIFR) and base-out fusional reserves (BOFR) and accommodation accuracy (AA)...
February 15, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28198731/a-review-of-techniques-to-measure-protein-sorption-to-soft-contact-lenses
#13
Brad Hall, James A Forrest, Lyndon Jones
PURPOSE: To compare and critically evaluate a variety of techniques to measure the quantity and biological activity of protein sorption to contact lenses over short time periods. METHODS: A literature review was undertaken investigating the major techniques to measure protein sorption to soft contact lens materials, with specific reference to measuring protein directly on lenses using in situ, ex situ, protein structural, and biological activity techniques. RESULTS: The use of in situ techniques to measure protein quantity provides excellent sensitivity, but many are not directly applicable to contact lenses...
February 14, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28114568/conjunctival-microbiome-changes-associated-with-soft-contact-lens-and-orthokeratology-lens-wearing
#14
Haikun Zhang, Fuxin Zhao, Diane S Hutchinson, Wenfeng Sun, Nadim J Ajami, Shujuan Lai, Matthew C Wong, Joseph F Petrosino, Jianhuo Fang, Jun Jiang, Wei Chen, Peter S Reinach, Jia Qu, Changqing Zeng, Dake Zhang, Xiangtian Zhou
Purpose: Usage of different types of contact lenses is associated with increased risk of sight-threatening complications. Changes in the ocular microbiome caused by contact lens wear are suggested to affect infection development in those individuals. To address this question, this study compares conjunctival microbial communities in contact lens wearers with those in noncontact lens wearers. Methods: Paired-end sequencing of the V3 region of the 16S rRNA gene was used to characterize the bacterial communities on the conjunctival surfaces of contact lens wearers and nonwearers...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28099282/risk-factors-for-acanthamoeba-keratitis-a-multistate-case-control-study-2008-2011
#15
Allison C Brown, Jonathan Ross, Daniel B Jones, Sarah A Collier, Tracy L Ayers, Robert M Hoekstra, Bryon Backensen, Sharon L Roy, Michael J Beach, Jonathan S Yoder
OBJECTIVE: To identify modifiable risk factors contributing to Acanthamoeba keratitis (AK) infection. METHODS: A case-control investigation was conducted. Case patients were soft contact lens wearers with laboratory-confirmed AK. Control were soft contact lens wearers ≥12 years of age, with no history of AK. Case patients were recruited from 14 ophthalmology referral centers and a clinical laboratory. Control were matched on state of residence and type of primary eye care provider (ophthalmologist or optometrist)...
January 17, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28099240/inter-relationship-of-soft-contact-lens-diameter-base-curve-radius-and-fit
#16
Graeme Young, Lee Hall, Anna Sulley, Kathrine Osborn-Lorenz, James S Wolffsohn
PURPOSE: To evaluate the inter-relationship of soft contact lens base curve radius (BC), diameter, and lens fit using a mathematical model. METHODS: A spreadsheet mathematical model was used to evaluate theoretical fitting characteristics for various combinations of soft lens BC and diameter. The designs were evaluated using ocular topography data collected from 163 UK subjects. The model evaluated lens tightness (edge strain) and on-eye diameter (horizontal corneal overlap) and assumed that acceptable values fell within the range 0 to 6% and 0...
January 18, 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28073689/corneo-scleral-contact-lens-in-a-piggyback-system-for-keratoconus-a-case-report
#17
Esteban Porcar, Juan Carlos Montalt, Enrique España-Gregori, Cristina Peris-Martínez
PURPOSE: We describe a case of fitting a corneo-scleral contact lens with a multi-aspheric geometry design (MAGD CScL) on top of a daily silicone hydrogel lens (piggyback system) for keratoconus management. METHODS: A 48-year-old man using soft toric contact lenses required an improvement in the unsatisfactory quality of his vision. He presented with bilateral asymmetric keratoconus with high myopia in the right eye (RE) and severe myopia in the left eye (LE). In addition, he had low vision in his LE because of a maculopathy...
January 7, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28067859/a-wirelessly-powered-smart-contact-lens-with-reconfigurable-wide-range-and-tunable-sensitivity-sensor-readout-circuitry
#18
Jin-Chern Chiou, Shun-Hsi Hsu, Yu-Chieh Huang, Guan-Ting Yeh, Wei-Ting Liou, Cheng-Kai Kuei
This study presented a wireless smart contact lens system that was composed of a reconfigurable capacitive sensor interface circuitry and wirelessly powered radio-frequency identification (RFID) addressable system for sensor control and data communication. In order to improve compliance and reduce user discomfort, a capacitive sensor was embedded on a soft contact lens of 200 μm thickness using commercially available bio-compatible lens material and a standard manufacturing process. The results indicated that the reconfigurable sensor interface achieved sensitivity and baseline tuning up to 120 pF while consuming only 110 μW power...
January 7, 2017: Sensors
https://www.readbyqxmd.com/read/28060146/combined-effect-of-ocular-and-multifocal-contact-lens-induced-aberrations-on-visual-performance-center-distance-versus-center-near-design
#19
Daniela Lopes-Ferreira, Paulo Fernandes, António Queirós, José M González-Meijome
PURPOSE: To evaluate the combined effects of inherent ocular aberrations and induced aberrations with a multifocal soft contact lens (MFCL) after 15 days of lens wear in presbyopic participants and their influence on visual performance at distance and near under high and low contrast conditions. METHODS: Forty presbyopic participants (mean age, 48.7±3.4) presenting a mean addition of 1.53±0.58 D were fitted with Biofinity Multifocal (CooperVision) and included in the study...
January 4, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28059368/measurement-of-thickness-and-profile-of-a-transparent-material-using-fluorescent-stereo-microscopy
#20
Zhenxing Hu, Tingge Xu, Huiyang Luo, Rong Z Gan, Hongbing Lu
Full-field thickness measurement for a thin transparent film is of interest for biological, medical, electronic, and packaging materials. It is a challenging task when the film is curvy, delicate and its thickness varies with location. We report herein a method to measure the thickness of a transparent (flat or curved) material and its topography using a stereo fluorescent profilometry technique. In this technique, two different types of fluorescent particles are deposited to both sides of the transparent film...
December 26, 2016: Optics Express
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