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Soft contact lens

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https://www.readbyqxmd.com/read/29899545/soft-transparent-graphene-contact-lens-electrodes-for-conformal-full-cornea-recording-of-electroretinogram
#1
Rongkang Yin, Zheng Xu, Ming Mei, Zhaolong Chen, Kai Wang, Yanlin Liu, Tao Tang, Manish Kr Priydarshi, Xuejuan Meng, Siyuan Zhao, Bing Deng, Hailin Peng, Zhongfan Liu, Xiaojie Duan
Visual electrophysiology measurements are important for ophthalmic diagnostic testing. Electrodes with combined optical transparency and softness are highly desirable, and sometimes indispensable for many ocular electrophysiology measurements. Here we report the fabrication of soft graphene contact lens electrodes (GRACEs) with broad-spectrum optical transparency, and their application in conformal, full-cornea recording of electroretinography (ERG) from cynomolgus monkeys. The GRACEs give higher signal amplitude than conventional ERG electrodes in recordings of various full-field ERG responses...
June 13, 2018: Nature Communications
https://www.readbyqxmd.com/read/29862064/characterization-of-soft-contact-lens-edge-fitting-during-daily-wear-using-ultrahigh-resolution-optical-coherence-tomography
#2
Lele Cui, Sisi Chen, Weihe Zhou, Kaixuan Sheng, Lei Zhang, Meixiao Shen, Ming Li
Purpose: To determine conjunctival overlap over the edge of soft contact lens and to visualize the peripheral postlens tear film (PoLTF) underneath soft contact lenses using ultrahigh-resolution optical coherence tomography (UHR-OCT). Methods: Twenty participants (4 males and 16 females, 23.0 ± 3.7 years) were fitted with two different types of soft contact lenses randomly. The limbus with lens was imaged with the UHR-OCT at the horizontal meridian every two hours up to 6 hours during lens wear...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29851781/acute-exacerbation-of-staphylococcal-catarrhal-infiltration-associated-with-treatment-for-pseudomonas-aeruginosa-keratitis-a-case-report
#3
Seung Pil Bang, Jong Hwa Jun
RATIONALE: Simultaneous presentation of peripheral infiltrates, which can be easily misidentified as satellite lesions, is rarely observed in patients with acute infectious keratitis. PATIENT CONCERNS: A 70-year-old woman was referred to our clinic due to acute mucopurulent keratitis following application of a therapeutic soft contact lens for the treatment of epithelial defects caused by entrance of soil foreign bodies into the eye. The patient was diagnosed with Pseudomonas keratitis, following which she was treated with alternating administration of fourth-generation fluoroquinolone (Vigamox) and 5% fortified ceftazidime eyedrops every 2 hours...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29849773/extended-low-oxygen-transmissibility-contact-lens-use-induces-alterations-in-the-concentration-of-proinflammatory-cytokines-enzymes-and-electrolytes-in-tear-fluid
#4
Luis Fernando Barba Gallardo, Martín Humberto Muñoz Ortega, Javier Ventura Juarez, Liseth Rubí Aldaba Muruato, Esperanza Sánchez Alemán, Eduardo Emmanuel Valdez Morales, Sugela Susana Blancas Zugarazo, Jose Rafael Villafan Bernal
Prolonged and continuous use of contact lenses for as long as 3 or 4 weeks is common in Mexico due to the low socioeconomic status, poor patient education and self-neglect. Furthermore, wearing contact lenses with low oxygen permeability is common due to their low cost. Thus, patients seek ophthalmologic evaluation due to signs and symptoms of overuse such as red eye, discomfort and tearing. In the present study, the effect of wearing soft contact lenses with a low oxygen permeability on the tear fluid composition after 1 day, 1 week and 1 month without removing them was examined...
May 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29787322/short-term-deposition-of-pm-2-5-particles-on-contact-lens-surfaces-effect-on-oxygen-permeability-and-refractive-index
#5
Zhizhang Dong, Xiaoyan Ding, Yong Li, Yifeng Gan, Yanhui Wang, Libin Xu, Yahong Wang, Zhou Ying, Juan Li
PURPOSES: To identify the deposition of fine (≤2.5 μm diameter) particulate matter (PM) particles (PM2.5 ), on contact lens surfaces and investigate the effects of such deposition on the oxygen permeability (OP) and refractive index (RI) of contact lenses. METHODS: A total of 36 contact lenses, including rigid gas permeable (RGP) and soft (SCL) lenses, was investigated. RGP (n=12) and SCL (n=12) (experimental group) lenses were incubated in a PM2.5 solution for 24 h, after which PM2...
May 22, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29739665/clinical-comparison-of-optimum-and-large-diameter-soft-contact-lenses
#6
James Wolffsohn, Lee Hall, Graeme Young
PURPOSE: To compare the clinical performance of large diameter lenses with optimally fit lenses in the same material and monocurve back surface design. METHOD: In a four-visit, randomised, bilateral, crossover, study, 25 myopic subjects wore optimum diameter lenses (control) and large diameter lenses (test) in random succession for 1 week each. Both study lenses were made of methafilcon A and of an identical design. Trial fittings with Frequency 55 (Coopervision) lenses modified with a design algorithm were used to determine the appropriate custom-made study lenses...
May 5, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29714326/compensating-additional-optical-power-in-the-central-zone-of-a-multifocal-contact-lens-forminimization-of-the-shrinkage-error-of-the-shell-mold-in-the-injection-molding-process
#7
Lien T Vu, Chao-Chang A Chen, Chia-Cheng Lee, Chia-Wei Yu
This study aims to develop a compensating method to minimize the shrinkage error of the shell mold (SM) in the injection molding (IM) process to obtain uniform optical power in the central optical zone of soft axial symmetric multifocal contact lenses (CL). The Z-shrinkage error along the Z axis or axial axis of the anterior SM corresponding to the anterior surface of a dry contact lens in the IM process can be minimized by optimizing IM process parameters and then by compensating for additional (Add) powers in the central zone of the original lens design...
April 20, 2018: Applied Optics
https://www.readbyqxmd.com/read/29691930/through-focus-optical-characteristics-of-monofocal-and-bifocal-soft-contact-lenses-across-the-peripheral-visual-field
#8
Qiuzhi Ji, Young-Sik Yoo, Hira Alam, Geunyoung Yoon
PURPOSE: To characterise the impact of monofocal soft contact lens (SCL) and bifocal SCLs on refractive error, depth of focus (DoF) and orientation of blur in the peripheral visual field. METHODS: Monofocal and two bifocal SCLs, Acuvue Bifocal (AVB, Johnson & Johnson) and Misight Dual Focus (DF, CooperVision) with +2.0 D add power were modelled using a ray tracing program (ZEMAX) based on their power maps. These SCLs were placed onto the anterior corneal surface of the simulated Atchison myopic eye model to correct for -3...
May 2018: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/29691927/safety-and-efficacy-following-10-years-of-overnight-orthokeratology-for-myopia-control
#9
Takahiro Hiraoka, Yasuo Sekine, Fumiki Okamoto, Toshifumi Mihashi, Tetsuro Oshika
PURPOSE: To compare rates of myopia progression and adverse events between orthokeratology (OK) and soft contact lens (SCL) wearers over a 10-year period in schoolchildren. METHODS: Medical records of consecutive patients (≤16 years of age at baseline) who started OK for myopia correction and continued the treatment for 10 years were retrospectively reviewed. For the control group, patients who started using soft contact lenses (SCLs) for myopia correction and continued to use them for 10 years were also reviewed...
May 2018: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/29656886/oscillatory-squeeze-film-analysis-of-soft-contact-lenses
#10
Éanna Mac Donnchadha, Cristina Leal, Harry Esmonde
The complex modulus of a soft contact lens affects the optical performance, fitting, on-eye movement, wettability, physiological impact and overall comfort of the lens. However, despite acknowledgement that the mechanical behaviour of contact lenses is time-dependent, the rheological characteristics of contact lenses remain under-defined. While existing studies have focussed on elasticity to describe lens behaviour, this paper proposes using oscillatory squeeze film analysis to evaluate the complex modulus...
April 13, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29643799/optical-coherence-tomography-examination-of-the-anterior-segment-in-a-case-of-corneal-perforation-and-lens-trauma-by-chestnut-burr
#11
Takashi Ono, Yosai Mori, Ryohei Nejima, Takuya Iwasaki, Shiro Amano, Kazunori Miyata
Chestnut burrs, the thorny encapsulation of chestnut fruit, can sometimes cause corneal injuries and ulceration, with poor prognoses. We report a case of corneal perforation and damaged anterior lens capsule due to a chestnut burr, using anterior segment optical coherence tomography (AS-OCT). A 67-year-old woman with a chestnut burr injury in her right eye was referred to our hospital. Her right best-corrected visual acuity (BCVA) was 0.8. Slit-lamp examination and AS-OCT showed perforation involving the endothelial layer at the center of the cornea...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29643713/modified-conjunctival-flap-as-a-primary-procedure-for-nontraumatic-acute-corneal-perforation
#12
Yi-Chen Sun, Jason P Kam, Tueng T Shen
Objective: Appropriate management of nontraumatic acute corneal perforation is always a challenge even with the many advances in surgical materials and techniques. We reported the outcomes of a case series of acute corneal perforation repair using a newly modified conjunctival flap with amniotic membrane transplant (AMT), fibrin glue, and a bandage soft contact lens (BCL). Materials and Methods: A total of 13 consecutive referral cases with nontraumatic acute corneal perforation at the University of Washington were reviewed...
January 2018: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/29611370/influence-of-sodium-hyaluronate-concentration-on-corneal-aberrations-in-soft-contact-lens-wearers
#13
Jong Soo Lee, Jong Moon Park, Hyun Kyung Cho, Su Jin Kim, Hyoun Do Huh, Young Min Park
PURPOSE: This study aimed to evaluate the influence of varying concentrations of sodium hyaluronate (SH) eye drops on corneal aberrations in normal individuals wearing silicone hydrogel contact lenses. METHODS: Normal individuals wearing silicone hydrogel contact lenses were enrolled in this study. Subjects were classified into two groups depending on the concentration of the preservative-free SH used (group 1, 0.1% SH; group 2, 0.3% SH). All subjects were asked to blink five times after instillation of the SH eye drop and before the Galilei measurements...
April 2018: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/29580955/intraepithelial-corneal-haemorrhage-in-a-rigid-contact-lens-wearer
#14
James Simpson, Stephen J Vincent
Intracorneal haemorrhage is a rare complication of modern contact lens wear. While a limited number of reports have described intracorneal haemorrhages (typically stromal) associated with the extended wear of soft contact lenses with limited oxygen permeability for the correction of aphakia, this case report documents the management and resolution of a significant intraepithelial corneal haemorrhage associated with long-term rigid contact lens wear for keratoconus and high myopia.
March 23, 2018: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29561497/visual-acuity-and-over-refraction-in-myopic-children-fitted-with-soft-multifocal-contact-lenses
#15
Krystal L Schulle, David A Berntsen, Loraine T Sinnott, Katherine M Bickle, Anita T Gostovic, Gilbert E Pierce, Lisa A Jones-Jordan, Donald O Mutti, Jeffrey J Walline
SIGNIFICANCE: Practitioners fitting contact lenses for myopia control frequently question whether a myopic child can achieve good vision with a high-add multifocal. We demonstrate that visual acuity is not different than spectacles with a commercially available, center-distance soft multifocal contact lens (MFCL) (Biofinity Multifocal "D"; +2.50 D add). PURPOSE: To determine the spherical over-refraction (SOR) necessary to obtain best-corrected visual acuity (BCVA) when fitting myopic children with a center-distance soft MFCL...
April 2018: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29471697/first-report-of-acanthamoeba-genotype-t8-human-keratitis
#16
Erika Orosz, Nóra Szentmáry, Huba J Kiss, Ágnes Farkas, István Kucsera, Zoltán Zsolt Nagy
Acanthamoeba has a worldwide distribution in the environment and it is capable of causing a painful sight-threatening disease of the cornea designated as Acanthamoeba keratitis (AK). Nowadays, the cases of AK have surged all over the world along with its disease burden due to increasing use of contact lenses used not only for optical correction but also for cosmetic purposes. In our present work, epithelial abrasion of a 27-year-old female soft contact lens wearer with keratitis was examined. Genotype identification was carried out with a real-time fluorescence resonance energy transfer polymerase chain reaction (PCR) assay based on sequence analysis of the 18S rRNA gene...
March 1, 2018: Acta Microbiologica et Immunologica Hungarica
https://www.readbyqxmd.com/read/29454097/improving-sustained-drug-delivery-from-ophthalmic-lens-materials-through-the-control-of-temperature-and-time-of-loading
#17
Ana Topete, Andreia S Oliveira, A Fernandes, T G Nunes, A P Serro, B Saramago
Although the possibility of using drug-loaded ophthalmic lens to promote sustained drug release has been thoroughly pursued, there are still problems to be solved associated to the different alternatives. In this work, we went back to the traditional method of drug loading by soaking in the drug solution and tried to optimize the release profiles by changing the temperature and the time of loading. Two materials commercially available under the names of CI26Y and Definitive 50 were chosen. CI26Y is used for intraocular lenses (IOLs) and Definitive 50 for soft contact lenses (SCLs)...
May 30, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29401882/optical-design-of-soft-multifocal-contact-lens-with-uniform-optical-power-in-center-distance-zone-with-optimized-nurbs
#18
Lien T Vu, Chao-Chang A Chen, Chia-Wei Yu
This study aims to develop a new optical design method of soft multifocal contact lens (CLs) to obtain uniform optical power in large center-distance zone with optimized Non-Uniform Rational B-spline (NURBS). For the anterior surface profiles of CLs, the NURBS design curves are optimized to match given optical power distributions. Then, the NURBS in the center-distance zones are fitted in the corresponding spherical/aspheric curves for both data points and their centers of curvature to achieve the uniform power...
February 5, 2018: Optics Express
https://www.readbyqxmd.com/read/29398904/a-single-vectored-thermal-pulsation-treatment-for-meibomian-gland-dysfunction-increases-mean-comfortable-contact-lens-wearing-time-by-approximately-4-hours-per-day
#19
Caroline A Blackie, Christy A Coleman, Kelly K Nichols, Lyndon Jones, Peter Q Chen, Ron Melton, David L Kading, Leslie E O'Dell, Sruthi Srinivasan
Purpose: To evaluate the effect of a single vectored thermal pulsation (VTP) treatment in contact lens wearers with meibomian gland dysfunction (MGD) and dry eye symptoms. Methods: The prospective, nonsignificant risk, open-label, randomized, multi-center clinical trial included 55 soft contact lens (SCL) wearers with MGD and evaporative dry eye. Subjects were randomized to the single VTP treatment group or an untreated control. The controls received a crossover VTP treatment at 3 months (crossover treatment group)...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29392323/association-between-ocular-surface-temperature-and-tear-film-stability-in-soft-contact-lens-wearers
#20
Takashi Itokawa, Yukinobu Okajima, Takashi Suzuki, Koji Kakisu, Hiroko Iwashita, Yoshitaka Murakami, Yuichi Hori
Purpose: To investigate the correlation between the changes in the ocular surface temperature (OST) and tear film stability over soft contact lenses (SCLs). Methods: We enrolled 20 eyes of 20 normal SCL wearers (20 men; 24.4 ± 4.1 years). We used four different daily disposable SCLs: one silicone hydrogel lens (delefilcon A) and three hydrogel lenses (etafilcon A with polyvinylpyrrolidone [PVP], etafilcon A, and polymacon). OST was measured every second during 10 seconds without blinking...
February 1, 2018: Investigative Ophthalmology & Visual Science
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