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persistent postural perceptual disorder

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https://www.readbyqxmd.com/read/30113791/-paradigm-shift-in-management-of-patients-with-vertigo-and-imbalance
#1
REVIEW
Andrea Mike, T László Tamás
Dizziness is one of the most common causes of medical visits. Management of the dizzy patient may be challenging both for the general practitioner, in emergency departments, and special clinics, as behind a seemingly homogeneous clinical presentation several very different etiologies may occur. Research of the last two century enriched our knowledge about physiology and pathophysiology of the vestibular system. Much knowledge is now available about the labyrinth being able to sense head motions and gravity, processing of afferent vestibular stimuli, reflectory oculomotor and postural control, or recovery of the vestibular system...
July 30, 2018: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29860587/reduced-cortical-folding-in-multi-modal-vestibular-regions-in-persistent-postural-perceptual-dizziness
#2
Salvatore Nigro, Iole Indovina, Roberta Riccelli, Giuseppe Chiarella, Claudio Petrolo, Francesco Lacquaniti, Jeffrey P Staab, Luca Passamonti
Persistent postural perceptual dizziness (PPPD) is a common functional vestibular disorder that is triggered and sustained by a complex interaction between physiological and psychological factors affecting spatial orientation and postural control. Past functional neuroimaging research and one recent structural (i.e., voxel-based morphometry-VBM) study have identified alterations in vestibular, visuo-spatial, and limbic brain regions in patients with PPPD and anxiety-prone normal individuals. However, no-one thus far has employed surface based morphometry (SBM) to explore whether cortical morphology in patients with PPPD differs from that of healthy people...
June 2, 2018: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29785522/non-invasive-vagus-nerve-stimulation-significantly-improves-quality-of-life-in-patients-with-persistent-postural-perceptual-dizziness
#3
Ozan E Eren, Filipp Filippopulos, Kristina Sönmez, Ken Möhwald, Andreas Straube, Florian Schöberl
Persistent postural-perceptual dizziness (PPPD) is one of the most common causes of chronic vestibular disorders, with a substantial portion of the affected patients showing no significant improvement to standard therapies (i.e., pharmacotherapy, behavioral psychotherapy). Patients with PPPD have been shown to have a significant comorbidity with anxiety disorders and depression. Further, these patients show an activation of the autonomic nervous system resulting in symptoms such as nausea, increase of heart rate, and sweating...
May 21, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29707579/cognitive-behavior-therapy-as-augmentation-for-sertraline-in-treating-patients-with-persistent-postural-perceptual-dizziness
#4
Yi-Chuan Yu, Hui Xue, Ying-Xin Zhang, Jiying Zhou
Background: Persistent postural-perceptual dizziness (PPPD) is a common vestibular disorder. This study was conducted to assess whether the addition of cognitive behavior therapy (CBT) could significantly improve the efficacy and acceptability of sertraline in treating PPPD. Methods: PPPD patients were recruited and randomly assigned to control and experiment groups. Patients in both groups received sertraline 50-200 mg/day, and only patients in the experiment group received CBT (twice a week, one hour per time)...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29208729/persistent-postural-perceptual-dizziness-pppd-a-common-characteristic-and-treatable-cause-of-chronic-dizziness
#5
REVIEW
Stoyan Popkirov, Jeffrey P Staab, Jon Stone
Persistent postural-perceptual dizziness (PPPD) is a newly defined diagnostic syndrome that unifies key features of chronic subjective dizziness, phobic postural vertigo and related disorders. It describes a common chronic dysfunction of the vestibular system and brain that produces persistent dizziness, non-spinning vertigo and/or unsteadiness. The disorder constitutes a long-term maladaptation to a neuro-otological, medical or psychological event that triggered vestibular symptoms, and is usefully considered within the spectrum of other functional neurological disorders...
February 2018: Practical Neurology
https://www.readbyqxmd.com/read/29167054/cerebral-gray-matter-changes-in-persistent-postural-perceptual-dizziness
#6
Sebastian Wurthmann, Steffen Naegel, Benedict Schulte Steinberg, Nina Theysohn, Hans-Christoph Diener, Christoph Kleinschnitz, Mark Obermann, Dagny Holle
BACKGROUND: Persistent postural perceptual dizziness (PPPD) is the most common vestibular syndrome in middle-aged patients. Multisensory maladjustment involving alterations of sensory response pattern including vestibular, visual and motion stimuli is thought to be a key pathophysiological correlate of this disorder. OBJECTIVE: We aimed to identify regional gray matter changes in PPPD patients that might be involved in the underlying pathophysiology of this disorder...
December 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29089920/altered-insular-and-occipital-responses-to-simulated-vertical-self-motion-in-patients-with-persistent-postural-perceptual-dizziness
#7
Roberta Riccelli, Luca Passamonti, Nicola Toschi, Salvatore Nigro, Giuseppe Chiarella, Claudio Petrolo, Francesco Lacquaniti, Jeffrey P Staab, Iole Indovina
BACKGROUND: Persistent postural-perceptual dizziness (PPPD) is a common functional vestibular disorder characterized by persistent symptoms of non-vertiginous dizziness and unsteadiness that are exacerbated by upright posture, self-motion, and exposure to complex or moving visual stimuli. Recent physiologic and neuroimaging data suggest that greater reliance on visual cues for postural control (as opposed to vestibular cues-a phenomenon termed visual dependence) and dysfunction in central visuo-vestibular networks may be important pathophysiologic mechanisms underlying PPPD...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29036855/diagnostic-criteria-for-persistent-postural-perceptual-dizziness-pppd-consensus-document-of-the-committee-for-the-classification-of-vestibular-disorders-of-the-b%C3%A3-r%C3%A3-ny-society
#8
Jeffrey P Staab, Annegret Eckhardt-Henn, Arata Horii, Rolf Jacob, Michael Strupp, Thomas Brandt, Adolfo Bronstein
This paper presents diagnostic criteria for persistent postural-perceptual dizziness (PPPD) to be included in the International Classification of Vestibular Disorders (ICVD). The term PPPD is new, but the disorder is not. Its diagnostic criteria were derived by expert consensus from an exhaustive review of 30 years of research on phobic postural vertigo, space-motion discomfort, visual vertigo, and chronic subjective dizziness. PPPD manifests with one or more symptoms of dizziness, unsteadiness, or non-spinning vertigo that are present on most days for three months or more and are exacerbated by upright posture, active or passive movement, and exposure to moving or complex visual stimuli...
2017: Journal of Vestibular Research: Equilibrium & Orientation
https://www.readbyqxmd.com/read/28002135/functional-dizziness-from-phobic-postural-vertigo-and-chronic-subjective-dizziness-to-persistent-postural-perceptual-dizziness
#9
Marianne Dieterich, Jeffrey P Staab
PURPOSE OF REVIEW: Functional dizziness is the new term for somatoform or psychogenic dizziness. The aim of this study is to review arguments for the new nomenclature, clinical features, possible pathomechanisms, and comorbidities of functional dizziness. RECENT FINDINGS: The prevalence of functional dizziness as a primary cause of vestibular symptoms amounts to 10% in neuro-otology centers. Rates of psychiatric comorbidity in patients with structural vestibular syndromes are much higher with nearly 50% and with highest rates in patients with vestibular migraine, vestibular paroxysmia, and Ménière's disease...
December 20, 2016: Current Opinion in Neurology
https://www.readbyqxmd.com/read/28002123/functional-dizziness-from-phobic-postural-vertigo-and-chronic-subjective-dizziness-to-persistent-postural-perceptual-dizziness
#10
REVIEW
Marianne Dieterich, Jeffrey P Staab
PURPOSE OF REVIEW: Functional dizziness is the new term for somatoform or psychogenic dizziness. The aim of this study is to review arguments for the new nomenclature, clinical features, possible pathomechanisms, and comorbidities of functional dizziness. RECENT FINDINGS: The prevalence of functional dizziness as a primary cause of vestibular symptoms amounts to 10% in neuro-otology centers. Rates of psychiatric comorbidity in patients with structural vestibular syndromes are much higher with nearly 50% and with highest rates in patients with vestibular migraine, vestibular paroxysmia, and Ménière's disease...
February 2017: Current Opinion in Neurology
https://www.readbyqxmd.com/read/27719862/functional-psychogenic-dizziness
#11
REVIEW
M Dieterich, J P Staab, T Brandt
Functional and psychiatric disorders that cause vestibular symptoms (i.e., vertigo, unsteadiness, and dizziness) are common. In fact, they are more common than many well-known structural vestibular disorders. Neurologists and otologists are more likely to encounter patients with vestibular symptoms due to persistent postural-perceptual dizziness or panic disorder than Ménière's disease or bilateral vestibular loss. Successful approaches to identifying functional and psychiatric causes of vestibular symptoms can be incorporated into existing practices without much difficulty...
2016: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/27686369/analysis-of-the-characteristics-of-persistent-postural-perceptual-dizziness-a-clinical-based-study-in-china
#12
Zhihui Yan, Liping Cui, Tianxia Yu, Hui Liang, Ying Wang, Chunfu Chen
OBJECTIVE: Persistent postural-perceptual dizziness (PPPD) is a common cause of chronic dizziness, but only a few studies have reported its clinical characteristics, and no related research has been performed in China. Therefore, the purpose of this study was to analyze the characteristics of PPPD for the first time in China. DESIGN: Data was collected from all patients during standard clinical practice, and further to evaluate the characteristics of PPPD comparing with the control group...
January 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/27638082/functional-and-psychiatric-vestibular-disorders
#13
REVIEW
J P Staab
Behavioral factors have long been recognized as affecting spatial orientation and balance function. Neuroanatomic and neurophysiologic studies conducted worldwide over the last 30 years have substantially advanced our knowledge about the inherently strong connectivity among threat/anxiety, vestibular, visual, and somatosensory systems in the brain. Clinical investigations have shed greater light on the nature of functional and psychiatric disorders that manifest or magnify vestibular morbidity. Concepts of these syndromes have changed over 150 years...
2016: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/26569392/persistent-postural-perceptual-dizziness-a-matter-of-higher-central-dysfunction
#14
Dagny Holle, Benedict Schulte-Steinberg, Sebastian Wurthmann, Steffen Naegel, Ilya Ayzenberg, Hans-Christoph Diener, Zaza Katsarava, Mark Obermann
OBJECTIVE: Persistent postural-perceptual dizziness (PPPD) is the most common vestibular disorder in the age group between 30 and 50 years. It is considered to be based on a multisensory maladjustment involving alterations of sensory response pattern including vestibular, visual and motion stimuli. Previous data supported a link between vestibular and pain mechanism. The aim of the study was to investigate whether other sensory inputs such as pain stimuli might be altered in terms of a more widespread central perception dysfunction in this disorder...
2015: PloS One
https://www.readbyqxmd.com/read/26410674/retrospective-review-and-telephone-follow-up-to-evaluate-a-physical-therapy-protocol-for-treating-persistent-postural-perceptual-dizziness-a-pilot-study
#15
REVIEW
Karla J Thompson, Jay C Goetting, Jeffrey P Staab, Neil T Shepard
BACKGROUND: Persistent postural-perceptual dizziness (PPPD) (formerly chronic subjective dizziness) may be treated using the habituation form of vestibular and balance rehabilitation therapy (VBRT), but therapeutic outcomes have not been formally investigated. OBJECTIVE: This pilot study gathered the first data on the efficacy of VBRT for individuals with well-characterized PPPD alone or PPPD plus neurotologic comorbidities (vestibular migraine or compensated vestibular deficits)...
2015: Journal of Vestibular Research: Equilibrium & Orientation
https://www.readbyqxmd.com/read/25809702/passive-motion-reduces-vestibular-balance-and-perceptual-responses
#16
Richard C Fitzpatrick, Shaun R D Watson
With the hypothesis that vestibular sensitivity is regulated to deal with a range of environmental motion conditions, we explored the effects of passive whole-body motion on vestibular perceptual and balance responses. In 10 subjects, vestibular responses were measured before and after a period of imposed passive motion. Vestibulospinal balance reflexes during standing evoked by galvanic vestibular stimulation (GVS) were measured as shear reaction forces. Perceptual tests measured thresholds for detecting angular motion, perceptions of suprathreshold rotation and perceptions of GVS-evoked illusory rotation...
May 15, 2015: Journal of Physiology
https://www.readbyqxmd.com/read/25666890/is-perception-of-vertical-impaired-in-individuals-with-chronic-stroke-with-a-history-of-pushing
#17
Avril Mansfield, Lindsey Fraser, Roshanth Rajachandrakumar, Cynthia J Danells, Svetlana Knorr, Jennifer Campos
Post-stroke 'pushing' behaviour appears to be caused by impaired perception of vertical in the roll plane. While pushing behaviour typically resolves with stroke recovery, it is not known if misperception of vertical persists. The purpose of this study was to determine if perception of vertical is impaired amongst stroke survivors with a history of pushing behaviour. Fourteen individuals with chronic stroke (7 with history of pushing) and 10 age-matched healthy controls participated. Participants sat upright on a chair surrounded by a curved projection screen in a laboratory mounted on a motion base...
March 17, 2015: Neuroscience Letters
https://www.readbyqxmd.com/read/25382427/clinical-characteristics-of-patients-with-persistent-postural-perceptual-dizziness
#18
Roseli Saraiva Moreira Bittar, Eliane Maria Dias von Söhsten Lins
INTRODUCTION: Persistent postural-perceptual dizziness is the dizziness that lasts for over three months with no clinical explanation for its persistence. The patient's motor response pattern presents changes and most patients manifest significant anxiety. OBJECTIVE: To evaluate the clinical characteristics of patients with persistent postural and perceptual dizziness. METHODS: statistical analysis of clinical aspects of patients with persistent postural-perceptual dizziness...
May 2015: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/10367289/real-time-continuous-visual-biofeedback-in-the-treatment-of-speech-breathing-disorders-following-childhood-traumatic-brain-injury-report-of-one-case
#19
B E Murdoch, G Pitt, D G Theodoros, E C Ward
The efficacy of traditional and physiological biofeedback methods for modifying abnormal speech breathing patterns was investigated in a child with persistent dysarthria following severe traumatic brain injury (TBI). An A-B-A-B single-subject experimental research design was utilized to provide the subject with two exclusive periods of therapy for speech breathing, based on traditional therapy techniques and physiological biofeedback methods, respectively. Traditional therapy techniques included establishing optimal posture for speech breathing, explanation of the movement of the respiratory muscles, and a hierarchy of non-speech and speech tasks focusing on establishing an appropriate level of sub-glottal air pressure, and improving the subject's control of inhalation and exhalation...
January 1999: Pediatric Rehabilitation
https://www.readbyqxmd.com/read/7189550/spatial-localization-in-cats-reared-with-strabismus
#20
C R Olson
1. The capacity for judging the location of an object relative to the body (egocentric localization) was assessed in cats by measuring the landing position attained when the cat jumped toward a platform viewed from a known distance. 2. Normal cats and kittens land at center of the platform when using one eye or both. In contrast, nine animals tested immediately after tenotomy of the medial rectus muscle of one eye all landed consistently off-center when using the operated eye. The direction of the error was predictable from the assumption that the cat was unaware of the eye's deviation from its natural position...
March 1980: Journal of Neurophysiology
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