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Qing Huang, Yongzhi Huang, Qu Luo, Wei Fan
BACKGROUND: We aimed to measure ocular biometric characteristics in older cataract patients from western China. METHODS: Ocular biometry records were retrospectively analyzed for 6933 patients with cataracts (6933 eyes) at least 50 years old who were treated at West China Hospital of Sichuan University. RESULTS: Partial coherence laser interferometry gave the following population averages: axial length (AL), 24.32 ± 2.42 mm; anterior chamber depth (ACD), 3...
April 17, 2018: BMC Ophthalmology
Eileen L Mayro, Lisa A Hark, Eric Shiuey, Michael Pond, Linda Siam, Tamara Hill-Bennett, Judie Tran, Nitasha Khanna, Marlee Silverstein, James Donaghy, Tingting Zhan, Ann P Murchison, Alex V Levin
PURPOSE: To determine the prevalence and severity of uncorrected refractive errors in school-age children attending Philadelphia public schools. METHODS: The Wills Eye Vision Screening Program for Children is a community-based pediatric vision screening program designed to detect and correct refractive errors and refer those with nonrefractive eye diseases for examination by a pediatric ophthalmologist. Between January 2014 and June 2016 the program screened 18,974 children in grades K-5 in Philadelphia public schools...
April 13, 2018: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Om Prakash Pant, Ji-Long Hao, Dan-Dan Zhou, Fan Wang, Cheng-Wei Lu
Small incision lenticule extraction (SMILE) is a minimally invasive, safe and flapless femtosecond laser technique used mainly to correct myopia through extraction of a corneal lenticule. Lenticules obtained in this way are transparent and of high quality, and thus, can be used to treat other corneal diseases. A 65-year-old male patient presented with recurrent pterygium complicated by thin cornea. The patient was treated surgically using a SMILE-extracted lenticule to avoid further complications and to maintain eyeball integrity...
January 1, 2018: Journal of International Medical Research
Alexander H Ward, Thomas T Norton, Carrie E Huisingh, Timothy J Gawne
During postnatal refractive development, an emmetropization mechanism uses refractive error to modulate the growth rate of the eye. Hyperopia (image focused behind the retina) produces what has been described as "GO" signaling that increases growth. Myopia (image focused in front of the retina) produces "STOP" signaling that slows growth. The interaction between GO and STOP conditions is non-linear; brief daily exposure to STOP counteracts long periods of GO. In young tree shrews, long-wavelength (red) light, presented 14 h per day, also appears to produce STOP signals...
April 12, 2018: Vision Research
Yuanjun Li, Hamza Miara, Pingbo Ouyang, Bing Jiang
Purpose: To determine the correlations between peripapillary vessel density, retinal nerve fibre layer (RNFL) thickness, and myopic indices at retina quadrants with optical coherence tomography angiography (OCTA) in Chinese. Methods: Fifty-six subjects with a mean spherical equivalent (MSE) of -3.63 ± 0.29 D were included. Peripapillary RNFL thickness and retinal vessel density in four sectors (superior, nasal, inferior, and temporal quadrants) were determined by OCTA, and correlations of the main outcomes were analyzed...
2018: Journal of Ophthalmology
Seung Yong Choi, Hyun-A Lim, Hyeon Woo Yim, Young-Hoon Park
PURPOSE: To investigate the association between oral fluoroquinolones (FQ) and the risk of rhegmatogenous retinal detachment (RRD) using a nationwide population-based study in Korea, designed to control for time-related bias. METHODS: As a nested case-control study within a cohort, the KNHIS-NSC 2002-2013 (Korean National Health Insurance Service National Sample Cohort) data used for the investigation. The subjects who visited an ophthalmologist were included in a cohort...
2018: PloS One
Majid Moshirfar, Jordan D Desautels, Brian D Walker, Michael S Murri, Orry C Birdsong, Phillip C Hoopes
Laser vision correction is a safe and effective method of reducing spectacle dependence. Photorefractive Keratectomy (PRK), Laser In Situ Keratomileusis (LASIK), and Small-Incision Lenticule Extraction (SMILE) can accurately correct myopia, hyperopia, and astigmatism. Although these procedures are nearing optimization in terms of their ability to produce a desired refractive target, the long term cellular responses of the cornea to these procedures can cause patients to regress from the their ideal postoperative refraction...
2018: Medical Hypothesis, Discovery and Innovation in Ophthalmology
Feng Zhao, Tian Han, Xun Chen, Zhi Chen, Ke Zheng, Xiaoying Wang, Xingtao Zhou
OBJECTIVES: To evaluate the relationship between pupillary response to light, myopia and disk halo size. DESIGN: Cross-sectional study. SETTING: Single refractive surgery centre. PARTICIPANTS: In this study, 197 right eyes of 197 patients between 20 and 35 years of age were evaluated for disk halo size and pupillary response to light with a vision monitor. PRIMARY AND SECONDARY OUTCOME MEASURES: Halo radius, age, spherical equivalent (SE), axial length (AL), initial diameter, amplitude of contraction, latency of contraction, duration of contraction, velocity of contraction, latency of dilation, duration of dilation, velocity of dilation, maximum pupil, minimum pupil, average pupil and dark pupil...
April 10, 2018: BMJ Open
Yin Guo, Li Juan Liu, Ping Tang, Yi Feng, Yan Yun Lv, Min Wu, Liang Xu, Jost B Jonas
Purpose: To assess the development and enlargement of the parapapillary gamma zone in school children. Methods: This school-based prospective longitudinal study included Chinese children attending grade 1 in 2011 and returning for yearly follow-up examinations until 2016. These examinations consisted of a comprehensive ocular examination with biometry and color fundus photographs. The parents underwent a standardized interview. The parapapillary gamma zone was defined as the area with visible sclera at the temporal optic disc margin, and the optic disc itself was measured on fundus photographs...
March 1, 2018: Investigative Ophthalmology & Visual Science
Junjie Deng, Xiaoli Li, Jiali Jin, Bo Zhang, Jianfeng Zhu, Haidong Zou, Xun Xu, Jingbo Xie, Ling Wang, Shaopin Zhu, Xiangui He
Purpose: To determine the relationship between choroidal thickness (ChT) at the posterior pole and refractive error and to explore the difference between the macular and peripapillary regions in children with myopia. Methods: A total of 340 healthy Chinese children underwent a series of comprehensive ocular examinations including cycloplegic refraction. Swept-source optical coherence tomography was used to measure the ChT in the macular and peripapillary regions...
March 1, 2018: Investigative Ophthalmology & Visual Science
Nethrajeith Srinivasalu, Sally A McFadden, Callan Medcalf, Lena Fuchs, Jessica Chung, Gayle Philip, Andrea Richardson, Moeen Riaz, Paul N Baird
Purpose: Posterior scleral remodeling accompanies myopia. In guinea pigs developing myopia, the region around the optic nerve (peripapillary zone, PPZ) rapidly expands followed by inhibition in eye size in the periphery. We studied the differential gene expression in the sclera that accompanies these changes. Methods: Guinea pigs were form-deprived (FD) for 2 weeks to induce myopia, while the fellow eye served as a control. After 2 weeks, the PPZ and the peripheral temporal sclera were isolated in representative animals to extract the RNA...
March 1, 2018: Investigative Ophthalmology & Visual Science
Cagatay Karaca, Zuleyha Karaca
Purpose: We evaluated the retinal effects of systemic metabolic changes clustered under the umbrella of metabolic syndrome (MetS) in comparison with age-matched healthy subjects. Methods: Spectral-domain optical coherence tomography (OCT) retinal segmentation analysis of 29 patients with MetS and 36 control subjects was performed. Patients with diabetes mellitus (DM), uncontrolled hypertension, retinopathy, high myopia or hyperopia, and posterior segment surgery, were excluded from analysis...
March 1, 2018: Investigative Ophthalmology & Visual Science
Yanin Suwan, Masoud Aghsaei Fard, Lawrence S Geyman, Apichat Tantraworasin, Toco Y Chui, Richard B Rosen, Robert Ritch
Importance: This study used optical coherence tomographic angiography to assess for impaired blood flow in myopic eyes with or without open-angle glaucoma. Objective: To compare the peripapillary perfused capillary density (PCD) between eyes with and without glaucoma. Design, Setting, and Participants: In this cross-sectional study at a tertiary glaucoma referral practice, we recruited patients with myopic eyes of spherical equivalent of more than -3...
April 5, 2018: JAMA Ophthalmology
Bing Liu, Xiongze Zhang, Lan Mi, Ling Chen, Feng Wen
Purpose: To investigate the relationship between simple hemorrhage (SH) associated with lacquer crack (LC) and myopic choroidal neovascularization (CNV) in high myopia. Methods: A cross-sectional evaluation including best-corrected visual acuity (BCVA), axial length, refractive error, color fundus photography, and spectral domain optical coherence tomography (SD-OCT) was performed in patients diagnosed with high myopia and SH. Fundus fluorescein angiography and indocyanine green angiography were performed if the eye was suspected with CNV...
2018: Journal of Ophthalmology
Soomin Lee, Da Ye Diana Choi, Dong Hui Lim, Tae Young Chung, Jong Chul Han, Changwon Kee
PURPOSE: To determine deep optic nerve head structure changes after transient intraocular pressure elevation during laser in situ keratomileusis (LASIK) for myopia. METHODS: Enhanced depth imaging-optical coherence tomography was performed in each myopic eye that underwent LASIK surgery. Enhanced depth imaging-optical coherence tomography images were created at postoperative 1 day, 1 week, 2 weeks, and 1 month. Lamina cribrosa (LC) thickness, LC depth and prelaminar thickness at the superior, middle and inferior portions of the optic nerve head were measured by two investigators...
March 13, 2018: Korean Journal of Ophthalmology: KJO
Sandra Gisbert, Frank Schaeffel
Following a hypothesis raised by M. and J. Neitz, Seattle, we have tested whether the abundance and the ratio of Long wavelength-sensitive (L) to Middle wavelength-sensitive (M) cones may affect eye size and development of myopia in the chicken. Fourteen chickens were treated with frosted plastic diffusers in front of one eye on day 10 post-hatching for a period of 7 days to induce deprivation myopia. Ocular dimensions were measured by A-scan ultrasonography at the beginning and at the end of the treatment and development of refractive state was tracked using infrared photorefraction...
March 30, 2018: Experimental Eye Research
Jing Zhao, Dongqiang Luo, Yong Sun, Lingling Niu, Feng Zhao, Xiaoying Wang, Hua Wang, Qian Chen, Xingtao Zhou
PURPOSE: To investigate the safety and efficacy of implanting a posterior chamber implantable collamer lens with a central hole in cases of high myopia with peripheral primary iris or ciliary body cysts. METHODS: A total of 37 eyes of 19 patients with primary iris or ciliary body cysts detected by ultrasonic biological microscope were included, with spherical powers of -10.26 ± 3.28 D and cylinder powers of -1.71 ± 1.18 D. Each patient received ultrasonic biological microscope and a routine examination before implantation of the implantable collamer lens...
March 1, 2018: European Journal of Ophthalmology
Ewa Grudzińska, Monika Modrzejewska
Myopia is the most common refractive error and the subject of interest of various studies assessing ocular blood flow. Increasing refractive error and axial elongation of the eye result in the stretching and thinning of the scleral, choroid, and retinal tissues and the decrease in retinal vessel diameter, disturbing ocular blood flow. Local and systemic factors known to change ocular blood flow include glaucoma, medications and fluctuations in intraocular pressure, and metabolic parameters. Techniques and tools assessing ocular blood flow include, among others, laser Doppler flowmetry (LDF), retinal function imager (RFI), laser speckle contrast imaging (LSCI), magnetic resonance imaging (MRI), optical coherence tomography angiography (OCTA), pulsatile ocular blood flowmeter (POBF), fundus pulsation amplitude (FPA), colour Doppler imaging (CDI), and Doppler optical coherence tomography (DOCT)...
2018: Journal of Ophthalmology
Nicola Rosa, Maddalena De Bernardo, Maria Borrelli
Purpose: To determine the unknown preoperative K readings (Kpre) to be used in history-based methods, for intraocular lens (IOL) power calculation in patients who have undergone myopic photorefractive keratectomy (PRK). Methods: A regression formula generated from the left eyes of 174 patients who had undergone PRK for myopia or for myopic astigmatism was compared with other methods in 168 right eyes. The Pearson index and paired t -test were utilized for statistical analysis...
2018: Journal of Ophthalmology
Yanping Zhou, Minlu Song, Minwen Zhou, Yiming Liu, Fenghua Wang, Xiaodong Sun
Purpose: To investigate the choroidal thickness (CT) and retinal thickness (RT) in highly myopic tessellated eyes. Methods: In this study, 115 highly myopic eyes were recruited and divided as tessellated fundus ( n = 93) and normal fundus ( n = 22). RT and CT were quantified using optical coherence tomography with enhanced depth imaging (EDI-OCT). Correlation between subfoveal CT (SFCT) and tessellation was analyzed using logistic regression models. Results: Tessellated fundus eyes had thinner CT than did normal fundus eyes, while RT was not statistically different across groups...
2018: Journal of Ophthalmology
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