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Saadiah Goolam, Nadia Carstens, Mark Ross, David Bentley, Margarida Lopes, John Peden, Zoya Kingsbury, Eleni Tsogka, Robyn Barlow, Trevor R Carmichael, Michèle Ramsay, Susan E Williams
Purpose: To report on a clinical and genetic investigation of a large, multigenerational South African family of mixed ancestry with autosomal dominant congenital cataracts, coloboma, and nystagmus. Methods: Ophthalmic examination was performed in 27 individuals from the same admixed South African family. DNA was sampled from either peripheral blood or buccal swabs in all 27 individuals, and whole genome sequencing was performed in six individuals. Sanger sequencing was used to validate the probable mutation in the remaining family members...
2018: Molecular Vision
Yun-Yun Sun, Shi-Fei Wei, Shi-Ming Li, Jian-Ping Hu, Xiao-Hui Yang, Kai Cao, Cai-Xia Lin, Jia-Ling Du, Ji-Yuan Guo, He Li, Luo-Ru Liu, Ian G Morgan, Ning-Li Wang
AIMS: To document the difference between non-cycloplegic and cycloplegic refraction and explore its associated factors in Chinese young adults. METHODS: A school-based study including 7971 undergraduates was conducted in Anyang, Henan Province, China. Cycloplegia was achieved with two drops of 1% cyclopentolate and 1 drop of Mydrin P (Tropicamide 0.5%, phenylephrine HCl 0.5%) with a 5 min interval. Non-cycloplegic and cycloplegic refractions were measured by an autorefractor...
June 21, 2018: British Journal of Ophthalmology
M Díaz Llopis, A Cisneros Lanuza
No abstract text is available yet for this article.
June 18, 2018: Archivos de la Sociedad Española de Oftalmología
Dan Fu, Lin Wang, Xingtao Zhou, Zhiqiang Yu
PURPOSE: To compare the functional optical zone (OZ) with different levels of myopia and different OZ groups after small-incision lenticule extraction. METHODS: This retrospective study included 249 patients (120 men) after small-incision lenticule extraction correction. We grouped participants according to attempted correction [low: spherical equivalent (SE) > -3.0 D; moderate: -6.0 D ≥ SE ≥ -3.0 D; high: SE ≥ -6.0 D] and planned functional optical zone (PFOZ) (OZ-1: PFOZ ≤ 6...
June 20, 2018: Cornea
Bozho Todorich, Maxwell S Stem, Tarek S Hassan, George A Williams, Lisa J Faia
BACKGROUND AND OBJECTIVE: To describe a novel technique of scleral indentation and transillumination for single-surgeon, unassisted vitrectomy and vitreous base shaving enhanced with a digital heads-up display system (NGENUITY 3D Visualization System; Alcon, Fort Worth, TX). PATIENTS AND METHODS: This technique was utilized in six eyes of six patients during vitrectomy surgery for common vitreoretinal surgical diagnoses. In each case, the transillumination was performed with the traditional intraocular light pipe set at 100% power, placed obliquely just posterior to the vitreous base insertion, with or without a transillumination adapter...
June 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Yueqing He, Shaoxue Zeng, Yunni Zhang, Junjun Zhang
BACKGROUND AND OBJECTIVE: This systematic review and meta-analysis was made to measure risk factors for retinal redetachment (re-RD) after silicone oil removal (SOR) in a quantitative method. PATIENTS AND METHODS: A comprehensive literature review relating to risk factors for re-RD after SOR was conducted before March 2017. Odds ratio (OR) with 95% confidence interval (CI) was calculated after data combination. RESULTS: Sixteen studies were included, and risk factors with significant differences found between the re-RD and control groups are as follows: aphakic eye (OR = 1...
June 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
Wei Hou, Thomas T Norton, Leslie Hyman, Jane Gwiazda
OBJECTIVES: Describe axial elongation using 14-year longitudinal data in a large, ethnically diverse group of myopic children, estimate age and axial length (AL) at stabilization, and evaluate associations between the progression and stabilization of AL and myopia. METHODS: Axial length was measured by A-scan ultrasonography annually. Axial length data were fit with individual polynomial functions and curve-based parameters (AL at stabilization and age at stabilization when annual rate of axial elongation ≤0...
July 2018: Eye & Contact Lens
Michael J Lipson, Moya M Brooks, Bruce H Koffler
The prevalence of myopia and high myopia has significantly increased worldwide and in the United States. The serious implications of these trends are being recognized. Myopia is not just a minor inconvenience requiring vision correction with glasses or contact lenses, but a disease process creating significant risk of serious vision-threatening eye disease. Various methods of treatment for myopia and myopic progression have been prescribed and studied in effort to find one that is effective, safe, and that patients will be compliant with...
July 2018: Eye & Contact Lens
Jeffrey J Walline, Marc W Robboy, Gene Hilmantel, Michelle E Tarver, Natalie A Afshari, Deepinder K Dhaliwal, Christie L Morse, Christopher J Quinn, Michael X Repka, Malvina B Eydelman
The prevalence of myopia is high and increasing. Approximately 5 billion people around the world are expected to be myopic by the year 2050. Methods to slow the progression of myopia and therefore potentially decrease the associated sight-threatening complications have been the subject of a number of investigations. A workshop, sponsored by the United States Food and Drug Administration (FDA) Center for Devices and Radiological Health, American Academy of Ophthalmology, American Academy of Optometry, American Association for Pediatric Ophthalmology and Strabismus, American Optometric Association, American Society of Cataract and Refractive Surgery, and Contact Lens Association of Ophthalmologists, Inc, convened myopia experts from around the world to discuss principles to consider in the design of clinical trials investigating the effectiveness and safety of myopia control devices...
July 2018: Eye & Contact Lens
Penny A Asbell, Kazuo Tsubota
No abstract text is available yet for this article.
July 2018: Eye & Contact Lens
Klaus Fiedler, Joscha Hofferbert, Franz Wöllert
The failure to exploit collective wisdom is evident in the conspicuous difficulty to solve hidden-profile tasks. While previous accounts focus on group-dynamics and motivational biases, the present research applies a metacognitive perspective to an ordinary learning approach. Assuming that evaluative learning is sensitive to the frequency with which targets are paired with positive versus negative attributes, selective repetition of targets' assets and deficits will inevitably bias the resulting evaluations...
2018: Frontiers in Psychology
Francisco Bandeira, Merce Morral, Daniel Elies, Sergio Eguiza, Spyridoula Souki, Felicidad Manero, Jose L Güell
Synopsis: Transitional toric intraocular lens (IOL) was developed to improve refractive outcomes in cataract surgery. We report refractive, vectorial outcomes, and stability of spherical equivalent over 12 months after implantation of this IOL. Purpose: To evaluate visual and refractive outcomes of a transitional conic toric intraocular lens (IOL) (Precizon® ) for the correction of corneal astigmatism in patients undergoing cataract surgery. Setting: The Ocular Microsurgery Institute (IMO), a private practice in Barcelona, Spain...
2018: Clinical Ophthalmology
Mark D Mifflin, Brent S Betts, Jason Nguyen, Severin Pouly
Purpose: To present refractive outcomes from consecutive cases with the Alcon Wavelight® EX500 excimer laser using photorefractive keratectomy (PRK) in patients with high myopia. Methods: A retrospective chart review of consecutive cases of high myopic eyes (≥6.0 Diopters [D]) undergoing PRK with the Alcon Wavelight EX500 excimer laser (Alcon Laboratories, Fort Worth, TX, USA) was done. Moderately high myopic eyes (6.0 to <8.0 D [6 D]) were compared with high myopic eyes (8...
2018: Clinical Ophthalmology
Dong Han, Danni Jiang, Jiahuan Zhang, Tianxu Pei, Qi Zhao
BACKGROUND: Many studies have shown that patients with intermittent exotropia have different degrees of damage to their stereopsis function. The purpose of this study is to explore the effect of different refractive status on stereopsis in children with intermittent exotropia(IXT). METHODS: We assessed 90 children of ages 4~ 16 years with intermittent exotropia at the Second Affiliated Hospital of Dalian Medical University during the years 2016-2017. According to their refractive status, the patients were divided into hyperopia group(spherical equivalent > or = - 1...
June 19, 2018: BMC Ophthalmology
Sanaa A Yassin, Amirah J Al-Dawood, Waseem M Al-Zamil, Mohammad A Al-Ghamdi, Zainab N Al-Khudairy
PURPOSE: To compare visual dysfunction between very preterm-born (VPB) children with no retinopathy of prematurity (no-ROP) at 6-10 years of age and age- and sex-matched full-term-born controls. METHODS: This is an observational, prospective study that included 30 children, 6-10 years of age, born ≤ 32 weeks of gestation, with no-ROP, and 30 age- and sex-matched full-term-born controls, conducted from January 2015 until August 2015. All children underwent complete ophthalmic evaluation...
June 18, 2018: International Ophthalmology
Sunali Goyal, Paul H Phillips, Mallikarjuna Rettiganti, Jeffrey M Gossett, R Scott Lowery
PURPOSE: To study the effect of cycloplegia on astigmatism measurements in pediatric patients with amblyopia. METHODS: This was a prospective comparative clinical study. Participants 4 to 17 years old were recruited from the patient population at the Arkansas Children's Hospital eye clinic after informed consent was obtained. Autorefractor measurements were used to obtain values of refractive error in amblyopic and non-amblyopic patients before and after cycloplegia...
June 18, 2018: Journal of Pediatric Ophthalmology and Strabismus
Taku Wakabayashi, Yasushi Ikuno, Nobuhiko Shiraki, Nagakazu Matsumura, Hirokazu Sakaguchi, Kohji Nishida
PURPOSE: The aim of this study was to investigate the efficacy of pars plana vitrectomy with inverted internal limiting membrane (ILM) insertion for macular hole retinal detachment (MHRD) in high myopia. METHODS: We studied 49 eyes of 49 consecutive patients who underwent vitrectomy for MHRD and were followed for more than 12 months postoperatively. Eyes that underwent vitrectomy with inverted ILM insertion from October 2013 to August 2015 were compared with eyes that underwent standard ILM peeling from October 2006 to September 2013...
June 18, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
Charlotte Melzer, Focke Ziemssen, Nicole Eter, Christian Brinkmann, Hansjuergen Agostini, Gisela Haeusser-Fruh, Uwe Rose, Marc Schargus, Katrin Lorenz, Frank G Holz, Steffen Schmitz-Valckenberg
PURPOSE: To assess the natural disease progression of high myopia in Caucasians considered at risk for the development of myopic choroidal neovascularization (mCNV). METHODS: Subjects were recruited in 25 clinical sites between June 2014 and June 2016. Main inclusion criteria included axial length of ≥26 mm, best-corrected visual acuity ≥0.05 decimal equivalent and presence of at least one out of five predefined morphological disease risk criteria. These were (1) subfoveal choroidal thinning < 50 µm, (2) enhanced choroidal curvature length > 6,300 µm, (3) lacquer cracks, (4) patchy atrophy > 5 mm2 and (5) preexisting mCNV in the fellow eye (German Clinical Trial Register DRKS00007761)...
June 15, 2018: Ophthalmologica. Journal International D'ophtalmologie
John C Norton, Sunali Goyal
PURPOSE: To determine patient characteristics and outcomes for developing retained nuclear fragments in the anterior chamber after phacoemulsification in at-risk populations. SETTING: University of Arkansas for Medical Sciences, Jones Eye Institute, Little Rock, Arkansas, USA. DESIGN: Retrospective case series. METHODS: Using Current Procedural Terminology codes 2006 to 2018, patients with a diagnosis of retained nuclear fragment in the anterior chamber after uncomplicated phacoemulsification cataract extraction were identified...
June 13, 2018: Journal of Cataract and Refractive Surgery
Tao Guo, Peng Gao, Li Fang, Li Guo, Yuchen Fan, Changgen Liu
The present prospective clinical observational study aimed to evaluate the efficacy of Toric intraocular lenses (IOL) to achieve rotational stability and astigmatism correction in eyes with high myopia. A total of 27 consecutive cataract patients (39 eyes) with pre-existing corneal astigmatism (1.5-3.5 D) were divided into two groups according to their refractive status: One group of 18 eyes with high myopia -(12.5-6.0 D) and another group consisting of 21 eyes with emmetropia or low myopia (-3.0-0.0 D). All eyes underwent cataract phacoemulsification surgeries by the same surgeon, with the implantation of an AcrySof® Toric IOL at the pre-designed degree...
June 2018: Experimental and Therapeutic Medicine
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