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PNES AND Seizures

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https://www.readbyqxmd.com/read/30077862/serum-gfap-level-a-novel-adjunctive-diagnostic-test-in-differentiate-epileptic-seizures-from-psychogenic-attacks
#1
Leila Simani, Mahboubeh Elmi, Marjan Asadollahi
PURPOSE: There has been increasing interest in the use of different biomarkers to help distinguish psychogenic from epileptic seizures, in patients presenting acutely with seizure-like events. In the present study, we measured serum glial fibrillary astrocytic protein (GFAP) levels in patients presenting with such events who were subsequently diagnosed as epileptic seizures (ESs) or psychogenic non-epileptic seizures (PNESs) and compared GFAP levels obtained with those found in healthy subjects...
July 23, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/30075361/emotion-dysregulation-in-patients-with-psychogenic-nonepileptic-seizures-a-systematic-review-based-on-the-extended-process-model
#2
REVIEW
Isobel Anne Williams, Liat Levita, Markus Reuber
Psychogenic nonepileptic seizures (PNES) are characterized by paroxysmal alterations in motor and sensory functions resembling epileptic seizures, but are not caused by epileptiform activity. In recent years, there has been increasing scientific interest in emotion dysregulation in patients with PNES (pwPNES), but the literature has not yet been interpreted within a broader model of emotion dysregulation. The aim of this review was therefore to synthesize the existing literature on emotion dysregulation in pwPNES within the extended process model (EPM) of emotion regulation...
July 31, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/30073861/preliminary-evidence-for-limbic-frontal-hyperexcitability-in-psychogenic-nonepileptic-seizure-patients
#3
Nash Boutros, Seung Suk Kang, Utku Uysal, Mian Urfy, Zack Thomas, Susan M Bowyer, Kathleen Gustafson
OBJECTIVES: The goal of the current pilot project was to probe the resting-state magnetoencephalography (MEG) in individuals with psychogenic nonepileptic seizures (PNES) and ascertain if there is evidence for frontal temporal cortical hyperexcitability, as evidenced by increased focal coherence in these regions. METHODS: Six patients with PNES and without any evidence of epilepsy were included. Nine healthy control (HC) subjects (age matched as a group) were also included...
August 3, 2018: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/30032094/sleep-in-psychogenic-nonepileptic-seizures-time-to-raise-a-red-flag
#4
Veronique Latreille, Gaston Baslet, Rani Sarkis, Milena Pavlova, Barbara A Dworetzky
Poor sleep is a frequent complaint in patients with psychogenic nonepileptic seizures (PNES). However, few studies have examined sleep problems in this population. We aimed to compare sleep complaints in patients with PNES with those with epilepsy. Subjects diagnosed as having PNES by experts using video-electroencephalography (vEEG) were recruited through the Brigham and Women's Hospital epilepsy monitoring unit (EMU) between 3/25/2013 and 3/29/2018. Controls were patients with epilepsy recruited through the EMU and subspecialty clinics...
July 19, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29993501/automated-detection-of-convulsive-seizures-using-a-wearable-accelerometer-device
#5
Shitanshu Kusmakar, Chandan Karmakar, Bernard Yan, Terence Obrien, Ramanathan Muthuganapathy, Marimuthu Palaniswami
Epileptic seizure detection requires specialized approaches such as video/electroencephalography monitoring. However, these approaches are restricted mainly to hospital setting and requires video/EEG analysis by experts, which makes these approaches resource- and labor-intensive. In contrast, we aim to develop a wireless remote monitoring system based on a single wrist-worn accelerometer device, which is sensitive to multiple types of convulsive seizures and is capable of detecting seizures with short duration...
June 11, 2018: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/29993463/automated-detection-of-convulsive-seizures-using-a-single-wrist-worn-accelerometer-device
#6
Shitanshu Kusmakar, Chandan Karmakar, Bernard Yan, Terence Obrien, Ramanathan Muthuganapathy, Marimuthu Palaniswami
Epileptic seizure detection requires specialized approaches such as video/electroencephalography monitoring. However, these approaches are restricted mainly to hospital setting and requires video/EEG analysis by experts, which makes these approaches resource- and labor-intensive. In contrast, we aim to develop a wireless, remote monitoring system using a single wrist-worn accelerometer sensor, which is sensitive to multiple types of convulsive seizures and is capable of detecting seizures with short duration...
June 11, 2018: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/29992307/sibling-controlled-study-of-parental-bonding-coping-and-urgent-health-care-use-in-families-with-children-with-nonepileptic-seizures
#7
Brenda Bursch, Marcy Forgey, Natacha D Emerson, Prabha Siddarth, Deborah M Weisbrot, Richard J Shaw, Julia Doss, Tatiana Falcone, Kyle Hinman, W Curt LaFrance, Rebecca Laptook, Matthew D Willis, Elissa L Deggelman, Rochelle Caplan, Sigita Plioplys
Objectives: Pediatric psychogenic nonepileptic seizures (PNES) is a functional somatic symptom condition with significant health-care service burden. While both family and individual factors play an important role in the development and maintenance of PNES, little is known about what predicts urgent health-care use in families with children who have PNES. The aim of the current study was to explore whether child coping and parental bonding styles influence the decision to seek urgent medical care in these families...
July 9, 2018: Journal of Pediatric Psychology
https://www.readbyqxmd.com/read/29981498/utilization-of-brain-imaging-in-evaluating-patients-with-psychogenic-nonepileptic-spells
#8
Danmeng Wei, Matthew Garlinghouse, Wenyang Li, Nicholas Swingle, Kaeli K Samson, Olga Taraschenko
BACKGROUND: Psychogenic nonepileptic spells (PNES) are paroxysmal movements or sensory events that resemble epileptic seizures but lack corresponding ictal electrographic changes. A confirmed diagnosis of PNES is only accomplished via video electroencephalogram (vEEG) monitoring. Prior to diagnosis, patients are often assessed with neurodiagnostic imaging and their conditions treated with anticonvulsant medications, both of which are of limited clinical value and contribute to the higher cost of care...
August 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29980425/characteristics-of-patients-with-confirmed-epilepsy-and-psychogenic-nonepileptic-seizures-in-qatar
#9
Stacy Schantz Wilkins, Boulenouar Mesraoua, Gonzalo Alarcón Palomo, Hassan Al Hail, Abdul Salam, Gayane Melikyan, Nabil Azar, Naim Haddad, Bassim Uthman, Maria Siddiqi, Lubna Elsheikh, Musab Ali, Abdulraheem Alrabi, Ashfaq Shuaib, Dirk Deleu, Ali A Asadi-Pooya
OBJECTIVE: The Middle Eastern country of Qatar opened its first epilepsy monitoring unit (EMU) in late 2015. This study compared demographic and clinical characteristics of patients with confirmed epilepsy to those of patients with confirmed psychogenic nonepileptic seizures (PNES). METHODS: Data were collected via retrospective chart review on 113 patients admitted for evaluation to the Qatar national health system EMU between November 2015 and May 2017. RESULTS: Seventy-one patients had a confirmed diagnosis (20 had PNES, 46 had epilepsy, 5 had both PNES and epilepsy)...
August 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29935759/neuropsychiatric-features-of-the-coexistence-of-epilepsy-and-psychogenic-nonepileptic-seizures
#10
Gislaine Baroni, William Alves Martins, Vitoria Piccinini, Marcelo Pereira da Rosa, Luciano de Paola, Eliseu Paglioli, Regina Margis, André Palmini
OBJECTIVE: To investigate demographic, epidemiologic and psychiatric features suggestive of the coexistence epilepsy (ES) and psychogenic nonepileptic seizures (PNES) that may contribute to precocious suspicion of the association. METHODS: In this exploratory study, all patients older than 16 years admitted to prolonged video-electroencephalogram monitoring were evaluated about demographic, epileptological and psychiatric features. Detailed psychiatric assessment using M...
August 2018: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/29906707/comorbid-depression-and-associated-factors-in-pnes-versus-epilepsy-systematic-review-and-meta-analysis
#11
REVIEW
Sean Walsh, Liat Levita, Markus Reuber
OBJECTIVES: This systematic review aims to contrast levels, manifestations and associations of depression in patients with psychogenic non-epileptic seizures (PNES) and those with epilepsy. METHODS: ScienceDirect and Web of Science were searched for primary research reports describing quantitative studies involving separate epilepsy and PNES samples (age 16+) and using a validated measure of depression. RESULTS: While 34 studies were identified, most were of low quality and had small sample sizes...
May 24, 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29787922/the-association-of-panic-and-hyperventilation-with-psychogenic-non-epileptic-seizures-a-systematic-review-and-meta-analysis
#12
REVIEW
Alaric M Indranada, Saul A Mullen, Roderick Duncan, David J Berlowitz, Richard A A Kanaan
INTRODUCTION: Psychogenic Non-Epileptic Seizures (PNES) are events that appear epileptic but are instead thought to have a psychological origin. Increased rates of several psychiatric disorders have been reported in PNES, including anxiety and panic disorders. Some theories suggest panic and/or hyperventilation have aetiological roles in PNES, though these remain unproven. METHODS: We conducted a systematic review of associations of panic and hyperventilation with PNES using Ovid Medline and PubMed, and a meta-analysis where appropriate...
July 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29763635/cortical-thickness-and-gyrification-patterns-in-patients-with-psychogenic-non-epileptic-seizures
#13
Marco Mcsweeney, Markus Reuber, Nigel Hoggard, Liat Levita
Psychogenic non-epileptic seizures (PNES) are often viewed as manifestations of altered motor and sensory function resulting from psychological responses to adverse experiences. Yet many patients and non-expert healthcare professionals find it difficult to understand how severe disturbances in normal neurological functioning can solely result from underlying psychological mechanisms to the exclusion of other physical causes. Perhaps importantly, recent advances using neuroimaging techniques point to possible structural and functional correlates in PNES...
June 21, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29761337/-psychogenic-non-epileptic-seizures-differential-diagnostic-features
#14
REVIEW
Philipp S Reif, Laurent M Willems, Adam Strzelczyk, Karl Martin Klein, Felix Rosenow
Psychogenic nonepileptic seizures (PNES) are to be considered in the differential diagnosis of a transient loss of consciousness. Their discrimination from syncope, epileptic seizures or vascular events can be difficult and requires profound knowledge about the semiology and clinical presentation of PNES and their differential diagnoses. Erroneous diagnoses and the resulting therapies lead to elevated morbidity, elevated costs and a poorer outcome. The aim of the present article is to provide an overview on PNES and their delineation from the clinical pictures of epilepsy and syncope...
May 14, 2018: Herzschrittmachertherapie & Elektrophysiologie
https://www.readbyqxmd.com/read/29754013/psychogenic-nonepileptic-seizures-in-adults-with-epilepsy-and-intellectual-disability-a-neglected-area
#15
Jans S van Ool, Alexandra I Haenen, Francesca M Snoeijen-Schouwenaars, Albert P Aldenkamp, Jos G M Hendriksen, H Jurgen Schelhaas, In Y Tan, Richard H C Lazeron, Nynke M G Bodde
PURPOSE: To describe the main characteristics of psychogenic nonepileptic seizures (PNES) in adults with epilepsy and intellectual disability (ID), and to analyse the differences regarding psychosocial functioning, epilepsy severity and ID between patients with PNES and a control group without PNES. METHODS: Medical records of adults with ID and epilepsy living at an epilepsy care facility (N = 240) were screened for PNES and evaluated by a neurologist. A control group consisting of patients with epilepsy and ID, without PNES, was matched according to age, sex and level of ID...
July 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29754012/clinical-spectrum-of-psychogenic-non-epileptic-seizures-in-children-an-observational-study
#16
Priyanka Madaan, Sheffali Gulati, Biswaroop Chakrabarty, Savita Sapra, Rajesh Sagar, Akbar Mohammad, R M Pandey, Manjari Tripathi
PURPOSE: The current study was designed to analyze the clinical spectrum of Psychogenic non-epileptic seizures (PNES) in children. METHODS: Children aged 6-16years with clinically suspected PNES, confirmed by short-term VEEG (STVEEG{video electroencephalogram}) and induction were classified as per Seneviratne classification. Stressors, associated co morbidities, Verbal IQ (Intelligence Quotient) and behavioral abnormalities were assessed using HTP(House tree person) test, DSM IV (Diagnostic and statistical manual of mental disorders) TR criteria, MISIC (Malin intelligence scale for Indian children) and CBCL (Child behaviour checklist)...
July 2018: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29750340/health-care-practitioners-perceptions-of-psychogenic-nonepileptic-seizures-a-systematic-review-of-qualitative-and-quantitative-studies
#17
Gregg H Rawlings, Markus Reuber
A recent systematic synthesis of qualitative research demonstrated that patients with psychogenic nonepileptic seizures (PNES) often experience unsatisfactory encounters with health care practitioners (HCPs). It is important to understand such interactions from the perspective of those responsible for delivering care. This systematic review aimed to examine the attitudes and perceptions of HCPs toward PNES. A systematic search of 3 databases (Web of Science, PubMed, and CINAHL) was conducted in November 2017...
June 2018: Epilepsia
https://www.readbyqxmd.com/read/29739840/characteristics-of-children-hospitalized-for-psychogenic-nonepileptic-seizures-due-to-conversion-disorder-versus-epilepsy
#18
Sarah K Luthy, Angela F Moss, Michelle R Torok, Lisa McLeod, Karen M Wilson
OBJECTIVES: Psychogenic nonepileptic seizures (PNES) are a manifestation of conversion disorder among children but can be difficult to distinguish from epilepsy. We sought to identify characteristics that differentiate children with PNES from those with epilepsy. METHODS: We conducted a retrospective cohort study of children admitted with epilepsy or PNES to 45 children's hospitals from 2004 to 2014. Children with PNES ( n = 399) versus those with epilepsy ( n = 13 241) were compared on demographic and clinical characteristics, testing, treatment, and health care use...
June 2018: Hospital Pediatrics
https://www.readbyqxmd.com/read/29709879/change-in-illness-perception-is-associated-with-short-term-seizure-burden-outcome-following-video-eeg-confirmation-of-psychogenic-nonepileptic-seizures
#19
David K Chen, Shirine Majmudar, Aarthi Ram, Holly C Rutherford, Melissa Fadipe, Callie B Dunn, Robert L Collins
OBJECTIVES: We aimed to evaluate whether potential changes in the patient's illness perception can significantly influence short-term seizure burden following video-electroencephalography (EEG) confirmation/explanation of psychogenic nonepileptic seizures (PNES). METHODS: Patients with PNES were dichotomized to two groups based on a five-point Symptom Attribution Scale: (a) those who prior to diagnosis perceived their seizures to be solely ("5") or mainly ("4") physical in origin (physical group) and (b) the remainder of patients with PNES (psychological group)...
June 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29709720/outcome-of-patients-with-psychogenic-nonepileptic-seizures-with-limited-resources-a-longitudinal-study
#20
Ali A Asadi-Pooya, Fateme Ziyaee
PURPOSE: The aim of the current study was to investigate the long-term outcome of patients with psychogenic nonepileptic seizures (PNES) and factors potentially associated with their outcome in Iran. METHODS: We investigated all patients with PNES admitted to the epilepsy monitoring unit at the Shiraz Comprehensive Epilepsy Center from 2008 through 2013. Patients included in this study had a confirmed diagnosis of PNES. In a phone call interview to the patients in December 2017, we obtained the following information: seizure outcome (seizure-free during the past 12 months or not), history of receiving any psychotherapy after confirming their diagnosis in the past, and number of psychotherapy sessions the patient had received...
July 2018: Seizure: the Journal of the British Epilepsy Association
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