Cong Yao, Shuichu Hao, Chun Zhang, Li Liu, Yumeng Jia, Peilin Meng, Cuiyan Wu, Xiong Guo
In this study, we conducted a systematic assessment of the effectsof Deoxynivalenol (DON) and T-2 mycotoxins on the developmental processes and structural integrity of murine femurs, considering both the isolated and synergistic effects of these toxins. To this end, we divided 72 male mice into nine groups, each subjected to varying dosages of T-2, DON, or their combinations. Over a four-week experimental period, meticulous monitoring was undertaken regarding the mice's body weight, biochemical markers of bone formation and resorption, and the activity of relevant cells...
April 9, 2024: Food and Chemical Toxicology