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https://www.readbyqxmd.com/read/29161799/risk-of-miscarriage-following-amniocentesis-and-chorionic-villus-sampling-a-systematic-review-of-the-literature
#1
Jaroslaw Beta, Cristina Lesmes-Heredia, Chiara Bedetti, Ranjit Akolekar
OBJECTIVES: To estimate the risk of miscarriage after amniocentesis or chorionic villus sampling (CVS) based on a systematic review of the literature. METHODS: A search of MEDLINE, EMBASE, and The Cochrane Library (2000-2017) was carried out to identify studies reporting complications following CVS or amniocentesis. The inclusion criteria for the systematic review were studies reporting results from large controlled studies (n≥1,000 invasive procedures) and those reporting data for pregnancy loss prior to 24 weeks' gestation...
November 21, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/29161798/intrapartum-care-quality-indicators-a-literature-review
#2
Elisa Lazzaretto, Antonella Nespoli, Simona Fumagalli, Elisabetta Colciago, Sofia Perego, Anna Locatelli
BACKGROUND: Quality of care is increasingly recognized as a critical aspect of the maternal and newborn health, mainly with respect to care around labour and delivery and in the immediate postnatal period. The Aim of this Review is to identify the recommended intrapartum care indicators in order to measure the quality of Midwifery care. METHODS: A structured literature search was conducted in August 2017 incorporating English and Italian language studies from 1993 and onwards to identify published articles on quality standards of intrapartum care...
November 21, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/29161776/awareness-on-cytology-procedure-in-oral-cancer-detection-among-undergraduates-an-institutional-study
#3
Gayathri Ramesh, Rajeev Pathak, Sunita Pathak, Amrita Raj, Amit Kumar, Anuradha Katiyar
Background: The screening and the early detection of the premalignant and malignant lesions are the only means for controlling the oral cancer which is known to be one of the leading causes for mortality worldwide. Oral exfoliative cytology though not a substitute for biopsy can be a powerful tool for its early detection. Dental Surgeons can play a great role in this direction. Aims and Objectives: The present study was undertaken to assess the self-reported knowledge and attitude regarding the early detection of oral cancer and exfoliative cytology among the undergraduates of Rama Dental College, Kanpur...
November 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/29161756/factors-to-improve-the-interobserver-agreement-for-gastric-atrophy-and-intestinal-metaplasia-consensus-of-definition-and-criteria
#4
Sung Sun Kim, Myeong-Cherl Kook, Ok-Ran Shin, Hee Sung Kim, Han-Ik Bae, Anna Seo, Do Youn Park, Il Ju Choi, Young-Il Kim, Byung Ho Nam, Sohee Kim
AIMS: Intestinal metaplasia and atrophy of the gastric mucosa are associated with Helicobacter pylori infection and are considered premalignant lesions. The updated Sydney system is used to these parameters but experienced pathologists and consensus processes are required for interobserver agreement. We sought to determine the influence of consensus process on assessment of intestinal metaplasia and atrophy. METHODS AND RESULTS: Two study sets were used; consensus set and validation set...
November 21, 2017: Histopathology
https://www.readbyqxmd.com/read/29161721/impact-of-nocturnal-noninvasive-ventilation-on-pulmonary-rehabilitation-in-patients-with-end-stage-lung-disease-awaiting-lung-transplantation
#5
Nikolaus Kneidinger, Rainer Gloeckl, Ursula Schönheit-Kenn, Katrin Milger, Wolfgang Hitzl, Jürgen Behr, Klaus Kenn
BACKGROUND: Pulmonary rehabilitation (PR) in patients awaiting lung transplantation is crucial to ensure a transplant benefit. However, PR in patients with end-stage lung disease treated with noninvasive ventilation (NIV) remains an area of uncertainty. OBJECTIVES: The aim of the study was to assess the potential benefit of PR in patients awaiting lung transplantation treated with NIV. METHODS: Patients awaiting lung transplantation who underwent comprehensive inpatient PR from 1998 to 2015 were retrospectively analyzed...
November 21, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/29161719/palmitic-acid-curcumin-ester-facilitates-protection-of-neuroblastoma-against-oligomeric-a%C3%AE-40-insult
#6
Zhangyang Qi, Meihao Wu, Yun Fu, Tengfei Huang, Tingting Wang, Yanjie Sun, Zhibo Feng, Changzheng Li
BACKGROUND/AIMS: The generation of reactive oxygen species (ROS) caused by amyloid-β (Aβ) is considered to be one of mechanisms underlying the development of Alzheimer's disease. Curcumin can attenuate Aβ-induced neurotoxicity through ROS scavenging, but the protective effect of intracellular curcumin on neurocyte membranes against extracellular Aβ may be compromised. To address this issue, we synthesized a palmitic acid curcumin ester (P-curcumin) which can be cultivated on the cell membrane and investigated the neuroprotective effect of P-curcumin and its interaction with Aβ...
November 20, 2017: Cellular Physiology and Biochemistry
https://www.readbyqxmd.com/read/29161706/endotoxin-effects-on-cardiac-and-renal-functions-and-cardiorenal-syndromes
#7
Grazia Maria Virzì, Anna Clementi, Alessandra Brocca, Claudio Ronco
Gram-negative sepsis is a major cause of morbidity and mortality in critical ill patients. Recent findings in molecular biology and in signaling pathways have enhanced our understanding of its pathogenesis and opened up opportunities of innovative therapeutic approaches. Endotoxin plays a pivotal role in the pathogenesis of multi-organ dysfunction in the setting of gram-negative sepsis. Indeed, heart and kidney impairments seem to be induced by the release of circulating pro-inflammatory and pro-apoptotic mediators triggered by endotoxin interaction with immune cells...
November 22, 2017: Blood Purification
https://www.readbyqxmd.com/read/29161687/obesity-knowledge-among-final-year-medical-students-in-norway
#8
Catia Martins, Anette Norsett-Carr
OBJECTIVES: To assess the level of obesity knowledge in final-year medical students in Norway and to compare it to an expert group and first-year medical students. METHODS: A 20-item questionnaire was specifically designed for this purpose (18 knowledge-based questions and 2 subjective questions looking at attitudes and self-perceived proficiency). All medical schools in Norway were included (n = 226). For comparison purposes, an expert group (n = 13) and first-year medical students (n = 96) were included...
November 22, 2017: Obesity Facts
https://www.readbyqxmd.com/read/29161678/preliminary-evaluation-of-pathogenic-bacteria-loading-on-organic-municipal-solid-waste-compost-and-vermicompost
#9
Nuhaa Soobhany
The use of composts or vermicomposts derived from organic fraction of Municipal Solid Waste (OFMSW) brought about certain disagreement in terms of high level of bacterial pathogens, thereby surpassing the legal restrictions. This preliminary study was undertaken to compare the evolution of pathogenic bacteria on OFMSW compost against vermicompost (generated by Eudrilus eugeniae) with promises of achieving sanitation goals. Analysis to quality data showed that OFMSW vermicomposting caused a moderately higher reduction in total coliforms in contrast to composting...
November 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29161622/on-denny-brown-s-spastic-dystonia-what-is-it-and-what-causes-it
#10
REVIEW
Jakob Lorentzen, Maud Pradines, Jean-Michel Gracies, Jens Bo Nielsen
In this review, we will work around two simple definitions of two different entities, which most often co-exist in patients with lesions to central motor pathways: Spasticity is "Enhanced excitability of velocity-dependent responses to phasic stretch at rest", which will not be the subject of this review, while Spastic dystonia is tonic, chronic, involuntary muscle contraction in the absence of any stretch or any voluntary command (Gracies, 2005). Spastic dystonia is a much less well understood entity that will be the subject this review...
November 4, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29161618/bayesian-synthesis-for-simulation-based-generation-of-probability-of-detection-pod-curves
#11
Mohamed Subair Syed Akbar Ali, Anish Kumar, Purnachandra B Rao, Jayakumar Tammana, Krishnan Balasubramaniam, Prabhu Rajagopal
This paper examines the feasibility of using Bayesian synthesis to reduce the number of experimental cases and trials required for generation of probability of detection (PoD) curves. A Bayesian framework is developed for the data-level combination of experimental and simulated datasets, in the context of the inspection of back-wall breaking notches in metallic samples by bulk ultrasonic shear waves. PoD curves generated using the proposed approach, where results from a reduced number of experimental defect cases and trials are used in combination with simulated datasets, are shown to compare well with those from the conventional approach using a large number of experiments...
November 4, 2017: Ultrasonics
https://www.readbyqxmd.com/read/29161577/histological-characteristics-of-the-gonads-of-pig-fetuses-and-their-relationship-with-fetal-anatomical-measurements
#12
Thais Preisser Pontelo, José Rafael Miranda, Matheus Augusto Rodrigues Felix, Barbara Azevedo Pereira, William Eduardo da Silva, Gleide Fernandes Avelar, Flávia Cristina Martins Queiroz Mariano, Gregório Corrêa Guimarães, Márcio Gilberto Zangeronimo
The objective was to evaluate the histomorphometric characteristics of the testis and ovaries of pig fetuses at different gestational ages, as well as their correlation with some fetus measurements. Forty-four fetuses were separated for gender (male and female) and gestational age (50, 80 and 106days of gestation). After slaughter, fetuses had their body length, head and thoracic perimeters measured and their gonads submitted to histomorphometric analyses. The gonadal characteristics at different gestational ages were statistically compared, correlations with the fetal measurements were performed and equations to predict the gonadal characteristics from the fetal measurements were obtained...
November 11, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/29161565/shape-control-cell-growth-hits-the-mechanical-buffers
#13
Andrew Fleming
Organs are made from cells whose individual growth rates differ, yet the final shape of organs is highly robust. A new mechanics-based system is proposed to physically restrain cells that grow more than their neighbours, buffering their influence on organ size and shape.
November 20, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/29161525/sea-cucumber-lipid-soluble-extra-fraction-prevents-ovalbumin-induced-allergic-airway-inflammation
#14
Da-In Lee, Shin Ae Kang, Anisuzzaman Md, U-Cheol Jeong, Feng Jin, Seok-Joong Kang, Jeong-Yeol Lee, Hak Sun Yu
In a previous study, our research group demonstrated that sea cucumber (Apostichopus japonicus) extracts ameliorated allergic airway inflammation through CD4(+)CD25(+)Foxp3(+) T (regulatory T; Treg) cell activation and recruitment to the lung. In this study, we aimed to determine which components of sea cucumber contribute to the amelioration of airway inflammation. We used n-hexane fractionation to separate sea cucumber into three phases (n-hexane, alcohol, and solid) and evaluated the ability of each phase to elevate Il10 expression in splenocytes and ameliorate symptoms in mice with ovalbumin (OVA)/alum-induced asthma...
November 21, 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29161522/development-of-a-measure-to-assess-parent-perceptions-of-barriers-to-child-weight-management
#15
Katherine E Darling, Amy F Sato, Manfred van Dulmen, Christopher Flessner, Geoffrey Putt
BACKGROUND: Families face many barriers related to creating or maintaining a healthy lifestyle, which likely contributes to the prevalence of childhood obesity in the United States; however, no measure currently exists to examine these barriers. This study developed a quantitative measure of parents' perceptions of barriers to family healthy lifestyle. METHODS: Parents of children between the ages of 7-17 were recruited using Amazon Mturk (n = 812). Exploratory and confirmatory factor analyses and preliminary convergent validity analyses were conducted...
November 21, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/29161513/insights-into-molecular-basis-of-acute-contact-toxicity-of-diverse-organic-chemical-in-honey-bee
#16
Xiao Li, Yuan Zhang, Hongna Chen, Huanhuan Li, Yong Zhao
The chemical pollutants, including pesticides and other industrial chemicals, have resulted in significant risks to the whole ecosystem. Therefore, the ecological risk assessment of chemicals is vital and necessary. Since honey bee (Apis mellifera) is probably among the most exposed species to the polluting chemicals, we focused on the in silico estimation of honey bee toxicity (HBT) of chemical and the analysis of the relevance of chemical HBT and several key physical-chemical properties and structural characteristics...
November 21, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/29161509/variation-in-the-supersaturation-and-phase-behavior-of-ezetimibe-amorphous-solid-dispersions-upon-dissolution-in-different-biorelevant-media
#17
Ahmed Elkhabaz, Sreya Sarkar, Janny K Dinh, Garth J Simpson, Lynne S Taylor
The delivery of poorly water-soluble drugs using amorphous solid dispersions (ASDs) has been widely acknowledged as a promising strategy for enhancing oral bioavailability. Upon dissolution, ASDs have accelerated dissolution rates and yield supersaturated solutions leading to higher apparent solubilities. Understanding the complex phase behavior of ASDs during dissolution is crucial for developing an effective formulation. Since the absorption of a lipophilic, high permeability drug is determined primarily by the intraluminal dissolution process and the final concentration achieved, there is a need for evaluation in biorelevant dissolution media that simulate both fasting and fed gastrointestinal states...
November 21, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/29161469/validation-of-a-definition-for-flare-in-patients-with-established-gout
#18
Angelo L Gaffo, Nicola Dalbeth, Kenneth G Saag, Jasvinder A Singh, Elizabeth J Rahn, Amy S Mudano, Yi-Hsing Chen, Ching-Tsai Lin, Sandra Bourke, Worawit Louthrenoo, Janitzia Vazquez-Mellado, Hansel Hernández-Llinas, Tuhina Neogi, Ana Beatriz Vargas-Santos, Geraldo da Rocha Castelar-Pinheiro, Rodrigo B C Amorim, Till Uhlig, Hilde B Hammer, Maxim Eliseev, Fernando Perez-Ruiz, Lorenzo Cavagna, Geraldine M McCarthy, Lisa K Stamp, Martijn Gerritsen, Viktoria Fana, Francisca Sivera, William Taylor
OBJECTIVE: To perform external validation of provisional gout flare (attack) definitions in patients with gout. METHODS: We enrolled 509 participants with gout from 17 international sites in a cross-sectional study performed during routine clinical care and collected data to classify participants as experiencing a gout flare or not according to a provisional definition. A local expert rheumatologist performed the final independent adjudication of the gout flare status...
November 21, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29161468/the-relationship-between-endogenous-%C3%AE-glucuronidase-activity-and-biologically-active-flavones-aglycone-contents-in-hairy-roots-of-baikal-skullcap
#19
V S Dikaya, A I Solovyeva, R A Sidorov, P A Solovyev, A Yu Stepanova
Here we examine the relationship between contents of principal flavones in hairy roots of Scutellaria baicalensis with the activity of the β-glucuronidase (sGUS) enzyme during a culturing cycle. Using RP-HPLC, we show that the highest contents of aglycones, baicalin and wogonin is observed at the growth days 8, 14 and 71 and reach 45, 41 and 62% (based on the total weight of hairy roots of the Baikal skullcap), correspondingly. Their accumulation is accompanied by increase of the sGUS activity, which we determined fluorometrically...
November 21, 2017: Chemistry & Biodiversity
https://www.readbyqxmd.com/read/29161459/ageing-impairs-parasite-specific-antibody-responses-in-cystic-echinococcosis
#20
Gustavo Mourglia-Ettlin, Sebastián Miles, Ana Hernández, Sylvia Dematteis
Humoral immunity wanes during healthy ageing, increasing susceptibility to infections in the elderly. In this sense, information about parasite infections and human immunosenescence is scarce. Cystic echinococcosis (CE) is an infectious disease caused by the larval stage of the cestode parasite Echinococcus granulosus, whose prevalence in humans shows an increase with host age. Susceptibility to human CE has been associated with humoral immunity to some extent; and therefore, we have here analyzed the influence of host age on the serological profile of young, middle-aged, and aged patients...
November 21, 2017: Parasite Immunology
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