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https://www.readbyqxmd.com/read/28817817/assessment-of-direct-to-consumer-genetic-testing-policy-in-korea-based-on-consumer-preference
#1
Gicheol Jeong
AIMS: In June 2016, Korea permitted direct-to-consumer genetic testing (DTC-GT) on 42 genes. However, both the market and industry have not yet been fully activated. Considering the aforementioned context, this study provides important insights. METHODS: The Korean DTC-GT policy assessment is based on consumer preference analysis using a discrete choice experiment. In August 2016, a web-based survey was conducted to collect data from 1,200 respondents. RESULTS: The estimation results show that consumers prefer a DTC-GT product that is cheap, tests various items or genes, offers accurate test results, and guarantees the confidentiality of all information...
August 18, 2017: Public Health Genomics
https://www.readbyqxmd.com/read/28816656/tracking-by-detection-of-3d-human-shapes-from-surfaces-to-volumes
#2
Chun-Hao Huang, Benjamin Allain, Edmond Boyer, Jean-Sebastien Franco, Federico Tombari, Nassir Navab, Slobodan Ilic
3D Human shape tracking consists in fitting a template model to temporal sequences of visual observations. It usually comprises an association step, that finds correspondences between the model and the input data, and a deformation step, that fits the model to the observations given correspondences. Most current approaches follow the Iterative-Closest-Point (ICP) paradigm, where the association step is carried out by searching for the nearest neighbors. It fails when large deformations occur and errors in the association tend to propagate over time...
August 15, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28815071/gastro-esophageal-junction-cancers-what-is-the-best-minimally-invasive-approach
#3
REVIEW
Egle Jezerskyte, Mark I van Berge Henegouwen, Miguel A Cuesta, Suzanne S Gisbertz
The short-term advantages of minimally invasive esophagectomy (MIE) in terms of less morbidity and better quality of life (QoL) in comparison with open esophagectomy (OE) became visible in the last few years. There are two main MIE approaches: a transthoracic esophagectomy (TTE) (either accompanied by an intrathoracic or cervical anastomosis) or a transhiatal esophagectomy (THE) (accompanied by a cervical anastomosis). Additionally, minimally invasive gastrectomy is increasingly gaining popularity over open gastrectomy...
July 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28813974/a-cosmetic-prosthetic-digit-with-bioinspired-embedded-touch-feedback
#4
Diego Barone, Marco D'Alonzo, Marco Controzzi, Francesco Clemente, Christian Cipriani
Partial hand amputation is the most frequent amputation level worldwide, accounting for approximately 90% of all upper limb amputations. Passive cosmetic prostheses represent one of the possible choices for its treatment, probably the most affordable one. However, these devices restore very limited motor function and subtle sensory feedback. The latter is an important component for restoring the body schema. In this work we present a simple yet potentially effective and low cost cosmetic digital prosthesis that embeds touch feedback; we dubbed this DESC-finger...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28812834/cost-effectiveness-of-rural-incentive-packages-for-graduating-medical-students-in-lao-pdr
#5
Eric Keuffell, Wanda Jaskiewicz, Khampasong Theppanya, Kate Tulenko
BACKGROUND: The dearth of health workers in rural settings in Lao People's Democratic Republic (PDR) and other developing countries limits healthcare access and outcomes. In evaluating non-wage financial incentive packages as a potential policy option to attract health workers to rural settings, understanding the expected costs and effects of the various programs ex ante can assist policy-makers in selecting the optimal incentive package. METHODS: We use discrete choice experiments (DCEs), costing analyses and recent empirical results linking health worker density and health outcomes to estimate the future location decisions of physicians and determine the cost-effectiveness of 15 voluntary incentives packages for new physicians in Lao PDR...
October 29, 2016: International Journal of Health Policy and Management
https://www.readbyqxmd.com/read/28810437/a-systematic-review-of-the-association-between-emotions-and-eating-behaviour-in-normal-and-overweight-adult-populations
#6
Tracey J Devonport, Wendy Nicholls, Christopher Fullerton
A systematic review was completed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive search of four electronic databases (2004-2015) yielded 60,017 articles, of which 29 met inclusion criteria. Included studies performed poorly on data quality analysis in terms of randomisation and controlling for confounding factors. Participant's body mass index scores range from 19.73 (standard deviation = 1.54) to 28.4 (standard deviation = 1.4) kg/m(2)...
March 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28806928/colour-polymorphic-lures-exploit-innate-preferences-for-spectral-versus-luminance-cues-in-dipteran-prey
#7
Thomas E White, Darrell J Kemp
BACKGROUND: Theory predicts that colour polymorphism may be favored by variation in the visual context under which signals are perceived. The context encompasses all environmental determinants of light availability and propagation, but also the dynamics of perception in receivers. Color vision involves the neural separation of information into spectral versus luminance channels, which often differentially guide specific tasks. Here we explicitly tested whether this discrete perceptual basis contributes to the maintenance of polymorphism in a prey-luring system...
August 14, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28806764/do-labeled-versus-unlabeled-treatments-of-alternatives-names-influence-stated-choice-outputs-results-from-a-mode-choice-study
#8
Wen Jin, Hai Jiang, Yimin Liu, Erica Klampfl
Discrete choice experiments have been widely applied to elicit behavioral preferences in the literature. In many of these experiments, the alternatives are named alternatives, meaning that they are naturally associated with specific names. For example, in a mode choice study, the alternatives can be associated with names such as car, taxi, bus, and subway. A fundamental issue that arises in stated choice experiments is whether to treat the alternatives' names as labels (that is, labeled treatment), or as attributes (that is, unlabeled treatment) in the design as well as the presentation phases of the choice sets...
2017: PloS One
https://www.readbyqxmd.com/read/28801426/patient-preferences-for-venous-thromboembolism-prophylaxis-after-injury-a-discrete-choice-experiment
#9
Bryce E Haac, Nathan N O'Hara, C Daniel Mullins, Deborah M Stein, Theodore T Manson, Herman Johal, Renan Castillo, Robert V O'Toole, Gerald P Slobogean
OBJECTIVE: Limited evidence for the optimal venous thromboembolism (VTE) prophylaxis regimen in orthopaedic trauma leads to variability in regimens. We sought to delineate patient preferences towards cost, complication profile, and administration route (oral tablet vs. subcutaneous injection). DESIGN: Discrete choice experiment (DCE). SETTING: Level 1 trauma center in Baltimore, USA. PARTICIPANTS: 232 adult trauma patients (mean age 47...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28797940/values-for-the-icecap-supportive-care-measure-icecap-scm-for-use-in-economic-evaluation-at-end-of-life
#10
Elisabeth Huynh, Joanna Coast, John Rose, Philip Kinghorn, Terry Flynn
End of life care may have elements of value that go beyond health. A generic measure of the benefits of end of life care could be helpful to decision makers. Such a measure, based on the capability approach, has recently been developed: the ICECAP Supportive Care Measure. This paper reports the first valuation exercise for that measure, with data from 6020 individuals collected from an on-line general population panel during June 2013. Individuals were asked to complete a stated choice experiment that combined best-worst scaling and a standard discrete choice experiment...
July 21, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28797859/valuing-attributes-of-home-palliative-care-with-service-users-a-pilot-discrete-choice-experiment
#11
Barbara Gomes, Maja de Brito, Vera P Sarmento, Deokhee Yi, Duarte Soares, Jacinta Fernandes, Bruno Fonseca, Edna Gonçalves, Pedro L Ferreira, Irene J Higginson
CONTEXT: Discrete choice experiment (DCE) is a quantitative method that helps determine which service attributes are most valued by people and consequently improve their well-being. OBJECTIVES: To test a new DCE on home palliative care (HPC). METHODS: Cross-sectional survey using the DCE method with adult patients and their family caregivers, users of three HPC services in Portugal. Service attributes were based on a Cochrane review, a meta-ethnography, and the few existing DCEs on HPC: 1) team's availability, 2) support for family caregivers, 3) homecare support, 4) information and planning, and 5) waiting time...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28797617/differences-in-waiting-list-prioritization-preferences-of-occupational-therapists-elderly-people-and-persons-with-disabilities-a-discrete-choice-experiment
#12
Marie-Hélène Raymond, Louise Demers, Debbie E Feldman
OBJECTIVE: To compare the preferences of occupational therapists, elderly people and adults with disabilities regarding prioritization criteria for occupational therapy waiting lists in home care. DESIGN: Discrete choice experiment survey. Respondents completed eight choice tasks where they were asked to choose which of two referral scenarios should be prioritized for services. Scenarios varied in terms of four attributes reflecting competing issues that come into play in waiting list prioritization: the person's ability to shower, ability to enter and exit the home, history of falls and time already spent on the waiting list...
August 7, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28782387/cost-analysis-of-leuprorelin-acetate-in-japanese-pre-menopausal-breast-cancer-patients-comparison-between-6-month-and-3-month-depot-formulations
#13
Rei Goto, Akihito Uda, Shinzo Hiroi, Kosuke Iwasaki, Kenta Takashima, Junichi Kurebayashi
AIMS: The aim in this study is to evaluate economic value for leuprorelin acetate 6-month depot compared with leuprorelin acetate 3-month depot in Japanese pre-menopausal breast cancer patients from a societal perspective. METHODS: The cost analysis was conducted by estimating direct and indirect cost, and intangible costs associated with one 6-month injection compared with two 3-month injections. Claims data were used for the analyses of direct and indirect cost and Medical Fee Schedule Table for direct cost...
August 16, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28776865/misreporting-and-econometric-modelling-of-zeros-in-survey-data-on-social-bads-an-application-to-cannabis-consumption
#14
William Greene, Mark N Harris, Preety Srivastava, Xueyan Zhao
When modelling "social bads," such as illegal drug consumption, researchers are often faced with a dependent variable characterised by a large number of zero observations. Building on the recent literature on hurdle and double-hurdle models, we propose a double-inflated modelling framework, where the zero observations are allowed to come from the following: nonparticipants; participant misreporters (who have larger loss functions associated with a truthful response); and infrequent consumers. Due to our empirical application, the model is derived for the case of an ordered discrete-dependent variable...
August 4, 2017: Health Economics
https://www.readbyqxmd.com/read/28771249/parental-preferences-toward-genomic-sequencing-for-non-medically-actionable-conditions-in-children-a-discrete-choice-experiment
#15
Megan A Lewis, Alex Stine, Ryan S Paquin, Carol Mansfield, Dallas Wood, Christine Rini, Myra I Roche, Cynthia M Powell, Jonathan S Berg, Donald B Bailey
PurposeApplication of whole-exome and whole-genome sequencing is likely to increase in clinical practice, public health contexts, and research. We investigated how parental preference for acquiring information from genome-scale testing is influenced by the characteristics of non-medically actionable genetic disorders in children, as well as whether the preferences differed by gender and between African-American and white respondents.MethodsWe conducted a Web-based discrete-choice experiment with 1,289 parents of young children...
August 3, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28770638/systematic-literature-review-comparing-rapid-3-dose-administration-of-the-gsk-tick-borne-encephalitis-vaccine-with-other-primary-immunization-schedules
#16
Ilaria Galgani, Eveline M Bunge, Lisa Hendriks, Christopher Schludermann, Cinzia Marano, Laurence De Moerlooze
Tick-borne encephalitis (TBE), which is endemic across large regions of Europe and Asia, is most effectively prevented through vaccination. Three-dose primary TBE vaccination schedules are either rapid (0,7,21-days) or conventional (0,28-84-days, 9-12-months). The second dose can also be administered at 14 days for faster priming and sero-protection). Areas covered: We used a three-step selection process to identify 21 publications comparing the immunogenicity and/or safety of different schedules. Expert commentary: Priming with two or three TBE vaccine doses was highly immunogenic...
September 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28764472/spectral-moments-vs-discrete-cosine-transformation-coefficients-evaluation-of-acoustic-measures-distinguishing-two-merging-german-fricatives
#17
Stefanie Jannedy, Melanie Weirich
The results of the quantification of the acoustic differences between German /ç/ and /ʃ/ in three speaker groups with varying contrast realizations are presented. Data for two speaker groups were collected in Berlin and Kiel, where the contrast is still realized. Data for a third group were collected in Berlin from speakers of Hood German-a youth-style multiethnolect spoken by adolescents in multilingual and multicultural neighborhoods of Berlin-where the contrast has weakened or is even lost. A forced choice perception test showed that listeners reliably differentiate these two fricatives in minimal pairs produced by the speakers from Berlin and Kiel, but fail to do so for the productions of the Hood German speakers...
July 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28761556/synchronization-of-generalized-reaction-diffusion-neural-networks-with-time-varying-delays-based-on-general-integral-inequalities-and-sampled-data-control-approach
#18
S Dharani, R Rakkiyappan, Jinde Cao, Ahmed Alsaedi
This paper explores the problem of synchronization of a class of generalized reaction-diffusion neural networks with mixed time-varying delays. The mixed time-varying delays under consideration comprise of both discrete and distributed delays. Due to the development and merits of digital controllers, sampled-data control is a natural choice to establish synchronization in continuous-time systems. Using a newly introduced integral inequality, less conservative synchronization criteria that assure the global asymptotic synchronization of the considered generalized reaction-diffusion neural network and mixed delays are established in terms of linear matrix inequalities (LMIs)...
August 2017: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/28758810/cost-analysis-of-leuprorelin-acetate-in-japanese-prostate-cancer-patients-comparison-between-6-month-and-3-month-depot-formulations
#19
Rei Goto, Akihito Uda, Shinzo Hiroi, Kosuke Iwasaki, Kenta Takashima, Mototsugu Oya
AIMS: This study aimed to evaluate the economic value for leuprorelin acetate 6-month depot compared with leuprorelin acetate 3-month depot from a societal perspective in Japanese prostate cancer patients. METHODS: The cost analysis estimated the reduction in direct and indirect costs as well as intangible costs saved by having one less injection. Claims data were used for the analyses of direct and indirect costs reduction. A discrete choice experiment based on a web-based survey estimated the monetary value of the intangible costs for one injection...
August 16, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28752549/choice-predicts-the-feedback-negativity
#20
Stuart McGill, Jude Buckley, Douglas Elliffe, Paul M Corballis
Choosing the appropriate response given the circumstance is integral to all aspects of human behavior. One way of elucidating the mechanisms of choice is to relate behavior to neural correlates. Electrophysiological evidence implicates the ERP feedback-negativity (FN) and the P300 as promising neural correlates of reward processing, an integral component of learning. However, prior research has not adequately addressed how the development of a preference to select one option over another (choice preference) relates to the FN and the P300...
July 28, 2017: Psychophysiology
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