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https://www.readbyqxmd.com/read/28637282/the-effect-of-predisposing-atheroembolic-risk-factors-on-renal-functional-recovery-between-laparoscopy-and-open-technique-in-patients-with-t1-stage-renal-cell-carcinoma-who-underwent-partial-nephrectomy-a-retrospective-comparison-study
#1
Sung Han Kim, Jae Young Joung, Ho Kyung Seo, Kang Hyun Lee, Jinsoo Chung
Objective: The present study aimed to determine the effect of an increasing number of predisposing atheroembolic risk factors on the development of chronic kidney disease (CKD) after partial nephrectomy (PN) in patients with T1-stage renal cell carcinoma (RCC). Methods: The study included 147 patients with T1-stage RCC with a normal contralateral kidney and without preoperative CKD, who underwent open (OPN, N = 83, 56.5%) or laparoscopic PN (LPN, N = 64, 43.5%) between 2003 and 2014...
June 14, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28584240/synthetic-surfactant-and-cross-linker-free-preparation-of-highly-stable-lipid-polymer-hybrid-nanoparticles-as-potential-oral-delivery-vehicles
#2
Taoran Wang, Jingyi Xue, Qiaobin Hu, Mingyong Zhou, Chao Chang, Yangchao Luo
The toxicity associated with concentrated synthetic surfactants and the poor stability at gastrointestinal condition are two major constraints for practical applications of solid lipid nanoparticles (SLN) as oral delivery vehicles. In this study, a synthetic surfactant-free and cross-linker-free method was developed to fabricate effective, safe, and ultra-stable lipid-polymer hybrid nanoparticles (LPN). Bovine serum albumin (BSA) and dextran varying in molecular weights were first conjugated through Maillard reaction and the conjugates were exploited to emulsify solid lipid by a solvent diffusion and sonication method...
June 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28515813/transperitoneal-laparoscopic-nephrectomy-assessing-complication-risk-in-cases-of-previous-abdominal-surgery
#3
Simon Ouellet, Robert Sabbagh, Claudio Jeldres
INTRODUCTION: We aimed to assess the effect of previous abdominal surgery on perioperative outcomes in patients undergoing transperitoneal laparoscopic partial (LPN) or radical (LRN) nephrectomy for renal masses. METHODS: We retrospectively reviewed all cases of LPN and LRN for renal masses at our institution between 2008 and 2014. Patients were divided in two groups, those with and without prior abdominal surgery. Four perioperative outcomes were compared, namely, operative time (OT), estimated blood loss (EBL), length of stay (LOS), and 30-days complications rate...
March 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28503237/modified-c-index-novel-predictor-of-postoperative-renal-functional-loss-of-laparoscopic-partial-nephrectomy
#4
Hiroki Ito, Kazuhide Makiyama, Takashi Kawahara, Kimito Osaka, Koji Izumi, Yumiko Yokomizo, Noboru Nakaigawa, Masahiro Yao
INTRODUCTION: We aimed to develop a scoring system to quantify the distance between the renal hilum and renal tumour, termed the modified C index (m-CI), and to predict renal functional loss (RFL) following laparoscopic partial nephrectomy (LPN). METHODS: The m-CI was measured by using computed tomography in 113 patients who underwent LPN between May 2003 and June 2014. The RFL following LPN was calculated by examining the estimated glomerular filtration rate (eGFR) and radioisotope renography one year postoperatively...
May 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28470171/co-delivery-of-paclitaxel-and-tetrandrine-via-irgd-peptide-conjugated-lipid-polymer-hybrid-nanoparticles-overcome-multidrug-resistance-in-cancer-cells
#5
Jinming Zhang, Lu Wang, Hon Fai Chan, Wei Xie, Sheng Chen, Chengwei He, Yitao Wang, Meiwan Chen
One of the promising strategies to overcome tumor multidrug resistance (MDR) is to deliver anticancer drug along with P-glycoprotein (P-gp) inhibitor simultaneously. To enhance the cancer cellular internalization and implement the controlled drug release, herein an iRGD peptide-modified lipid-polymer hybrid nanosystem (LPN) was fabricated to coload paclitaxel (PTX) and tetrandrine (TET) at a precise combination ratio. In this co-delivery system, PTX was covalently conjugated to poly (D,L-lactide-co-glycolide) polymeric core by redox-sensitive disulfide bond, while TET was physically capsulated spontaneously for the aim to suppress P-gp in advance by the earlier released TET in cancer cells...
May 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28411326/neck-muscle-emg-force-relationship-and-its-reliability-during-isometric-contractions
#6
Riccardo Lo Martire, Kristofer Gladh, Anton Westman, Björn O Äng
BACKGROUND: Susceptible to injury, the neck is subject to scientific investigations, frequently aiming to elucidate possible injury mechanisms via surface electromyography (EMG) by indirectly estimating cervical loads. Accurate estimation requires that the EMG-force relationship is known and that its measurement error is quantified. Hence, this study examined the relationship between EMG and isometric force amplitude of the anterior neck (AN), the upper posterior neck (UPN), and the lower posterior neck (LPN) and then assessed the relationships' test-retest reliability across force-percentiles within and between days...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28407628/super-selective-artery-embolization-before-laparoscopic-partial-nephrectomy-in-treating-renal-angiomyolipoma
#7
Chao Qin, YiChun Wang, Pengchao Li, Pu Li, Jun Tao, Pengfei Shao, Qiang Lv
INTRODUCTION: To investigate the feasibility and efficiency of super-selective artery embolization (SAE) before laparoscopic partial nephrectomy (LPN) in treating renal angiomyolipoma (RAML). MATERIALS AND METHODS: A retrospective analysis was conducted on 36 consecutive patients who underwent SAE before LPN (group A, n = 16) or LPN directly (group B, n = 20) from June 2010 to March 2016. Intraoperative blood loss, blood transfusion, operation time, warm ischemia time (WIT), and prognosis were compared between groups...
April 14, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28381117/a-multi-centered-propensity-matched-analysis-comparing-laparoscopic-and-open-surgery-for-pt3a-renal-cell-carcinoma
#8
Premal Patel, Jasmir G Nayak, Zhihui Liu, Olli Saarela, Michael Jewett, Ricardo A Rendon, Anil Kapoor, Peter Black, Simon Tanguay, Jun Kawakami, Ronald Moore, Rodney H Breau, Chris Morash, Frederic Pouliot, Darrel Drachenberg
INTRODUCTION: To compare outcomes following laparoscopic renal surgery (LRS) and open renal surgery (ORS) in the treatment of pathological T3a (pT3a) renal cell carcinoma (RCC) using a propensity matched analysis. MATERIALS & METHODS: The Canadian Kidney Cancer Information System is a prospectively maintained database for patients diagnosed with RCC from 15 Canadian institutions. Patients treated for non-metastatic pT3a RCC between 2008-2015 were included. Propensity score matching for age, gender, tumor size, grade, histology and surgical approach were performed to compare laparoscopic radical and partial nephrectomy (LRN or LPN) with open radical or partial nephrectomy (ORN or OPN)...
April 5, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28348492/hospital-resource-intensity-and-cirrhosis-mortality-in-united-states
#9
Amit K Mathur, Apurba K Chakrabarti, Jessica L Mellinger, Michael L Volk, Ryan Day, Andrew L Singer, Winston R Hewitt, Kunam S Reddy, Adyr A Moss
AIM: To determine whether hospital characteristics predict cirrhosis mortality and how much variation in mortality is attributable to hospital differences. METHODS: We used data from the 2005-2011 Nationwide Inpatient Sample and the American Hospital Association Annual survey to identify hospitalizations for decompensated cirrhosis and corresponding facility characteristics. We created hospital-specific risk and reliability-adjusted odds ratios for cirrhosis mortality, and evaluated patient and facility differences based on hospital performance quintiles...
March 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28319992/organizational-and-community-factors-associated-with-magnet-status-of-u-s-hospitals
#10
Teresa Wai Chi Tai, Sherry I Bame
The Magnet Recognition Program for healthcare organizations promotes excellence in nursing services and professional practices. However, organizational and community characteristics that contribute to the adoption of Magnet status remain unexplained. Investigating organizational and community factors will help determine systematic structural and contextual dimensions of Magnet hospitals previously shown to be more cost-effective in comparison with non-Magnet hospitals. Using the baseline 2005 database of all Magnet hospitals in the United States, the authors selected a matched sample to determine key organizational and community characteristics associated with Magnet adoption while controlling for regional and local factors...
January 2017: Journal of Healthcare Management / American College of Healthcare Executives
https://www.readbyqxmd.com/read/28304214/retroperitoneal-laparoscopic-partial-nephrectomy-for-tumors-larger-than-7%C3%A2-cm-in-renal-cell-carcinoma-initial-experience-of-single-institution
#11
Erlin Song, Xin Ma, Ruihua An, Peng Zhang, Xu Zhang, Baojun Wang, Taoping Shi, Shengkun Sun
BACKGROUND: To report our initial experience dealing with retroperitoneal laparoscopic partial nephrectomy (LPN) for tumors larger than 7 cm in renal cell carcinoma (RCC). MATERIALS AND METHODS: A total of 15 patients with malignant tumors larger than 7 cm underwent retroperitoneal LPN at our institution. Patient baseline demographics, perioperative outcomes, pathological characteristics, and estimated glomerular filtration rate (eGFR) were analyzed retrospectively in our collected database...
March 17, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28297337/one-year-analysis-of-elekta-cbct-image-quality-using-nps-and-mtf
#12
Satomi Nakahara, Masayuki Tachibana, Yoichi Watanabe
The image quality (IQ) of imaging systems must be sufficiently high for image-guided radiation therapy (IGRT). Hence, users should implement a quality assurance program to maintain IQ. In our routine IQ tests of the kV cone-beam CT system (Elekta XVI), image noise was quantified by noise standard deviation (NSD), which was the standard deviation of CT numbers measured in a small area in an image of an IQ test phantom (Catphan), and the high spatial resolution (HSR) was evaluated by the number of line-pairs (LPN) visually recognizable in the image...
May 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28259881/retrospective-analysis-of-laparoscopic-partial-nephrectomies-using-the-zero-ischemia-technique
#13
Leonid Boyarsky, Avi Stein, Alex Konstantinovsky, Dmitry Goldin, Ilan Klein, Tal May, Yuval Freifeld, Yahya Moaad, Yoram Dekel
PURPOSE: To report a series of 89 off-clamp laparoscopic partial nephrectomies (LPN) performed without using any additional "nephron sparing" manipulations. METHODS: Retrospective analysis of surgical characteristics, complications, postoperative results, and renal function changes. RESULTS: Between March 2008 and May 2014, 89 LPN using zero ischemia technique were performed. Most of the patients (61.8%) were male. The median age was 62 years (23-88)...
March 4, 2017: Urologia Internationalis
https://www.readbyqxmd.com/read/28222178/effect-of-meal-composition-on-postprandial-lipid-concentrations-and-lipoprotein-particle-numbers-a-randomized-cross-over-study
#14
Meena Shah, Manall Jaffery, Beverley Adams-Huet, Brian Franklin, Jonathan Oliver, Joel Mitchell
BACKGROUND: It is unclear how high-protein (HP) and high-monounsaturated fat (HMF) meals affect postprandial blood lipids and lipoprotein particle numbers (LPN). PURPOSE: To compare a HP versus a HMF meal on postprandial lipid and LPN responses. METHODS: Twenty-four participants (age: 36.3±15.0 years; body mass index: 23.6±2.0 kg/m2; 45.8% female) were fed a HP (31.9% energy from protein) and a HMF (35.2% fat and 20.7% monounsaturated fat) meal in a randomized cross-over trial design...
2017: PloS One
https://www.readbyqxmd.com/read/28216925/feasibility-of-laparoscopic-partial-nephrectomy-in-the-obese-patient-and-assessment-of-predictors-of-perioperative-outcomes
#15
Evan Jonathan Wiens, Deepak Kumar Pruthi, Ruchi Chhibba, Thomas Brian McGregor
INTRODUCTION: Partial nephrectomy is the gold standard for treatment of small renal masses. Our study compares outcomes for obese (body mass index [BMI] ≥30) and healthy (BMI <30) patients undergoing laparoscopic partial nephrectomy (LPN) with the intention of defining preoperative risk factors for complications and renal insufficiency in the obese. MATERIALS AND METHODS: We conducted a retrospective review of 187 consecutive patients who underwent LPN. We examined the association between BMI and postoperative complication, estimated blood loss (EBL), hospital length of stay, warm ischemic time (WIT), and postoperative renal function...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28199267/organizational-and-community-factors-associated-with-magnet-status-of-u-s-hospitals
#16
Teresa Wai Chi Tai, Sherry I Bame
The Magnet Recognition Program for healthcare organizations promotes excellence in nursing services and professional practices. However, organizational and community characteristics that contribute to the adoption of Magnet status remain unexplained. Investigating organizational and community factors will help determine systematic structural and contextual dimensions of Magnet hospitals previously shown to be more cost-effective in comparison with non-Magnet hospitals. Using the baseline 2005 database of all Magnet hospitals in the United States, the authors selected a matched sample to determine key organizational and community characteristics associated with Magnet adoption while controlling for regional and local factors...
January 2017: Journal of Healthcare Management / American College of Healthcare Executives
https://www.readbyqxmd.com/read/28187730/adherence-to-treatment-guidelines-the-association-between-stroke-risk-stratified-comparing-chads2-and-cha2ds2-vasc-score-levels-and-warfarin-prescription-for-adult-patients-with-atrial-fibrillation
#17
Scott A Chapman, Catherine A St Hill, Meg M Little, Michael T Swanoski, Shellina R Scheiner, Kenric B Ware, M Nawal Lutfiyya
BACKGROUND: Ischemic stroke is a risk associated with atrial fibrillation (AF) and is estimated to occur five times more often in afflicted patients than in those without AF. Anti-thrombotic therapy is recommended for the prevention of ischemic stroke. Risk stratification tools, such as the CHADS2, and more recently the CHA2DS2-VASc, for predicting stroke in patients with AF have been developed to determine the level of stroke risk and assist clinicians in the selection of antithrombotic therapy...
February 11, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28186431/application-of-three-dimensional-visualization-technology-in-laparoscopic-partial-nephrectomy-of-renal-tumor-a-comparative-study
#18
Zhi Wang, Lin Qi, Peng Yuan, Xiongbing Zu, Wei Chen, Zhenzhen Cao, Yuan Li, Long Wang
PURPOSE: To compare the effectiveness and safety of individualized three-dimensional visualization technology (3DVT) on surgical planning and perioperative outcomes in laparoscopic partial nephrectomy (LPN) for renal cell carcinoma (RCC) with routine computed tomography (CT) examination in the treatment of renal tumor. METHODS: From May 2015 to March 2016, a total of 94 patients with cT1 RCC who underwent surgical treatment in our department were analyzed retrospectively...
May 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28127771/nurse-related-clinical-nonlicensed-personnel-in-u-s-hospitals-and-their-relationship-with-nurse-staffing-levels
#19
Suhui Li, Patricia Pittman, Xinxin Han, Timothy John Lowe
OBJECTIVE: This study examines nurse-related clinical nonlicensed personnel (CNLP) in U.S. hospitals between 2010 and 2014, including job categories, trends in staffing levels, and the possible relationship of substitution between this group of workers and registered nurses (RNs) and/or licensed practical nurses (LPNs). DATA SOURCE: We used 5 years of data (2010-2014) from an operational database maintained by Premier, Inc. that tracks labor hours, hospital units, and facility characteristics...
February 2017: Health Services Research
https://www.readbyqxmd.com/read/28124281/a-single-centre-experience-of-zero-ischaemia-laparoscopic-partial-nephrectomy-in-ireland
#20
C Browne, P E Lonergan, E M Bolton, F D'Arcy, T H Lynch
BACKGROUND: Nephron-sparing surgery in the form of partial nephrectomy is increasingly becoming the standard of care in patients with small renal tumours. Oncological outcomes for partial nephrectomy are equivalent to radical nephrectomy, however, clamping of the hilar vessels to allow resection of tumours during partial nephrectomy may cause ischaemic damage to the kidney and result in long-term renal impairment. AIM: We carried out a retrospective review of 43 patients undergoing laparoscopic partial nephrectomy (LPN) and assessed functional and oncological outcomes...
January 25, 2017: Irish Journal of Medical Science
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