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Nasal cytology

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https://www.readbyqxmd.com/read/29123440/eosinophil-chemokines-and-clara-cell-protein-16-production-in-nasal-mucosa-of-patients-with-persistent-allergic-rhinitis
#1
Aleksandar Perić, Cveta Špadijer Mirković, Biserka Vukomanović Đurđević, Aneta V Perić, Danilo Vojvodić
Objective: Eotaxin-2 and regulated on activation normal T cell expressed and secreted (RANTES) are involved in the eosinophil trafficking in patients with persistent allergic rhinitis (PAR). Clara cell protein 16 (CC16) is an anti-inflammatory protein mainly produced by the epithelial non-ciliated Clara cells. The aim of this study was to investigate the production of CC16 and chemokines eotaxin-2 and RANTES in nasal mucosa of patients with PAR. Materials and Methods: Twenty-one PAR patients and 20 healthy participants were included...
October 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/29077152/pathological-and-cytological-changes-of-the-nasal-mucosa-in-acute-rhinosinusitis-the-role-of-hyaluronic-acid-as-supportive-therapy
#2
A Ciofalo, G Zambetti, G Altissimi, M Fusconi, P Soldo, M Gelardi, G Iannella, B Pasquariello, G Magliulo
OBJECTIVE: The aim of this study was to evaluate the reparative role of hyaluronic acid in acute rhinosinusitis (ARS). PATIENTS AND METHODS: 48 patients affected by ARS were submitted to nasal endoscopy, nasal cytology, mucociliary transport evaluation (MCTt) and visual analogue scale questionnaire (VAS) at T0, after 14-18 days (T1) and after 30-35 days (T2). The patients were randomized into two groups, A and B, and received Levofloxacin and Prednisone. Moreover, using a nebulizer ampoule for nasal douche, Group A received high molecular weight Sodium Hyaluronate (3%) plus saline solution (NaCl 0...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29059673/efficacy-of-buffered-hypertonic-saline-nasal-irrigation-for-nasal-symptoms-in-children-with-seasonal-allergic-rhinitis-a-randomized-controlled-trial
#3
Velia Malizia, Salvatore Fasola, Giuliana Ferrante, Giovanna Cilluffo, Laura Montalbano, Massimo Landi, Donatella Marchese, Giovanni Passalacqua, Stefania La Grutta
BACKGROUND: Saline nasal irrigation is labelled as an add-on treatment in patients with allergic rhinitis (AR). The primary aim of this study was to compare the efficacy of 21-day use of buffered hypertonic saline (BHS) versus normal saline solution (NSS) on reducing nasal symptoms in children with seasonal AR (SAR). Comparing their efficacy on nasal cytology counts (NCC), quality of life, and sleep quality was the secondary aim. METHODS: In this 21-day, open-label, randomized controlled study, 36 SAR children (aged 6-13 years) with a Total 5 Symptom Score (T5SS) ≥5 received twice-daily BHS or NSS delivered through a nasal douche...
2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29038613/nasal-cytology-as-a-marker-of-atopy-in-children
#4
Anna Mierzejewska, Anna Jung, Bolesław Kalicki
The aim of this study was to evaluate the cytological picture of nasal mucosa in children with atopic diseases and to determine the diagnostic value of the test for the diagnosis of atopic diseases. The study included 140 children from 4 months to 17 years old. Among children with a history of atopy, there were 30 children with atopic dermatitis, 30 children with asthma, and 46 children with allergic rhinitis. The control group consisted of 34 healthy children. The nasal scraping technique has been used to collect samples from the nasal cavity...
2017: Disease Markers
https://www.readbyqxmd.com/read/28982291/intranasal-melanoma-treated-with-radiation-therapy-in-three-dogs
#5
Owen Davies, Sarah Spencer, Slavomira Necova, Emma Holmes, Angela Taylor, Laura Blackwood, Ana Lara-Garcia
Three dogs were investigated for chronic unilateral nasal discharge. In all cases CT imaging showed an intranasal mass causing turbinate lysis and no evidence of metastasis. Cytology in cases 1 (a 14-year-old neutered male crossbreed dog) and 2 (a five-year-old neutered male German Shepherd dog) demonstrated a pleomorphic cell population with variable intracellular pigment suspicious of melanocytic neoplasia. Histopathology with immunohistochemistry (Melan-A and vimentin, plus PNL-2 in one case) confirmed the diagnosis of melanoma in all dogs...
October 6, 2017: Veterinary Quarterly
https://www.readbyqxmd.com/read/28913874/an-algorithmic-approach-to-diagnose-haematolymphoid-neoplasms-in-effusion-by-combining-morphology-immunohistochemistry-and-molecular-cytogenetics
#6
L Chen, J S Zhang, D G Liu, D Cui, Z L Meng
OBJECTIVE: There are limited studies of cytology diagnosis of haematopoietic and lymphoid tumours in serosal effusion except for occasional case reports. We would like to demonstrate an algorithmic approach for accurate diagnosis, especially in patients without previous history. METHODS: We reviewed 36 cases of lymphoma diagnosed in serosal effusion following an algorithmic approach. Suspected tumour cells were classified into small, intermediate and large sizes and two characteristic forms of plasmacytoid and Reed Sternberg-like on smears (step 1), followed by utilising panels of immunohistochemical markers and Epstein-Barr encoding region in situ hybridisation on cell blocks (step 2)...
September 15, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28905513/large-cell-neuroendocrine-carcinoma-of-the-maxillary-sinus-on-fine-needle-aspiration-cytology-report-of-a-rare-case-with-a-focus-on-pitfalls-in-diagnosis
#7
Akihiko Kawahara, Takeharu Ono, Akiko Sumi, Hideyuki Abe, Yorihiko Takase, Kazuya Murata, Tomohiko Yamaguchi, Yoshiki Naito, Jun Akiba
Head and neck large cell neuroendocrine carcinoma (LCNEC) is a rare high-grade malignant tumor with neuroendocrine differentiation. We report a case of LCNEC causing difficulty in cytological diagnosis. A 60-year-old man with right-sided face pain presented with a swelling at the right cheek, and he complained of right nasal obstruction and lacrimation. Preoperative fine-needle aspiration cytology (FNAC) showed high cellularity, with a moderate number of clusters of tumor cells on an abundant necrotic background...
September 14, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28831372/an-unusual-case-of-recurrent-chest-infections
#8
Taqua Dahab, Shahzaib Saleem, Dikshaini Gumani, Brian Casserly, Claire Sharkey, Frank Laghi, William Newmarch
This case presentation relates to a 53 year old male, cachectic in appearance, who presented with progressively worsening dyspnoea, cough, intermittent haemoptysis and a history of nasal dryness ongoing over five months. The patient had received multiple courses of oral antibiotics for suspected community acquired pneumonia with no significant improvement. He was referred to our Respiratory Department for further evaluation of his symptoms. His HRCT showed right middle lobe consolidation with central cavitations...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28801511/paraneoplastic-mucous-membrane-pemphigoid-with-ocular-and-laryngeal-involvement
#9
Silvia Lambiel, Pavel Dulguerov, Emmanuel Laffitte, Igor Leuchter
A 73-year-old woman was treated 8 years previously for synchronous breast and uterine neoplasms. She presented with a severe sore throat, odynophagia, dysphonia, dyspnoea, ocular irritation and weight loss over the last 3 months. Physical examination revealed ulcerations in the oral cavity, posterior pharyngeal wall and supraglottic larynx, nasal crusting, bilateral conjunctivitis and three cutaneous blisters. A diagnosis of anti-laminin 5 mucous membrane pemphigoid was retained, based on skin biopsy, direct immunofluorescence and immunoprecipitation...
August 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28748192/extranodal-nk-t-cell-lymphoma-nasal-type-presenting-as-refractory-pseudomonas-aeruginosa-facial-cellulitis
#10
Erika Reategui Schwarz, Katerina G Oikonomou, Megan Reynolds, Juliette Kim, Rajeev L Balmiki, Stephanie A Sterling
Extranodal natural killer T-cell lymphoma, nasal type (ENKL), formerly called lethal midline granuloma or angiocentric T-cell lymphoma, is a predominantly extranodal non-Hodgkin lymphoma characterized by vascular damage, necrosis, and an association with Epstein-Barr virus. In the United States, it is more frequently seen in Asian, Asian Pacific Islander, and Hispanic descent populations and is more prevalent in males in their fifth decade. Clinical presentation of NK nasal lymphoma most commonly involves epistaxis; obstruction; discharge; destructive mass in sinuses, palate, and nose; and skin ulceration...
July 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/28680302/eosinophilic-granulomatosis-with-polyangiitis-presented-as-acute-polyneuropathy-and-cerebral-vasculitis
#11
Il-Han Yoo, Sang Tae Choi, Seong-Ho Choi, Jeong-Min Kim, Suk-Won Ahn
Eosinophilic granulomatosis with polyangiitis (EGPA) is an immune related systemic disease that is caused by vasculitis affecting multiple organ systems. It is characterized by asthma, fever, eosinophilia, cardiac problems, renal injury, and peripheral neuropathy. In this report, we describe a patient with EGPA with concurrent cerebral infarction and acute polyneuropathy mimicking a Guillain-Barre syndrome (GBS). A 46-year-old man presented with rapidly progressing gait disturbance, muscular weakness, and tingling sensation in all four limbs...
June 2017: Experimental Neurobiology
https://www.readbyqxmd.com/read/28677353/individualized-treatment-of-allergic-rhinitis-according-to-nasal-cytology
#12
Jianjun Chen, Yue Zhou, Li Zhang, Yanjun Wang, Amber N Pepper, Seong H Cho, Weijia Kong
PURPOSE: Nasal cytology is important in the diagnosis and treatment of nasal inflammatory diseases. Treatment of allergic rhinitis (AR) according to nasal cytology has not been fully studied. We plan to explore the individualized treatment of AR according to nasal cytology. METHODS: Nasal cytology from 468 AR patients was examined for inflammatory cell quantity (grade 0-5) and the percentage of neutrophils and eosinophils. Results were subdivided into the following categories: AR(Eos), eosinophil ≥50% of the whole inflammatory cells; AR(Neu), neutrophils ≥90%; AR(Eos/Neu), 10%≤ eosinophil <50%; AR(Low), grade 0/1 inflammatory cell quantity...
September 2017: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/28665504/prognostic-value-of-nasal-cytology-and-clinical-factors-in-nasal-polyps-development-in-patients-at-risk-can-the-beginning-predict-the-end
#13
Eugenio De Corso, Daniela Lucidi, Mariapina Battista, Matteo Romanello, Carla De Vita, Silvia Baroni, Chiara Autilio, Jacopo Galli, Gaetano Paludetti
BACKGROUND: We evaluated the prognostic value of nasal cytology and clinical factors in predicting nasal polyp (NP) development in patients with history of nonallergic chronic sinonasal inflammation. METHODS: This was a retrospective case-control study of 295 patients followed at our institution for a mean of 85.70 ± 19.41 months. According to the inclusion criteria we enrolled 84 cases with persistent eosinophilic nonallergic sinonasal inflammation (group A) and 106 cases with neutrophilic inflammation (group B), both without evidence of NPs at the baseline...
September 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28657531/-analysis-of-nasal-cytology-in-children-and-adolescents-with-rhinitis
#14
Natalia A Lozano, Ricardo J Saranz, Alejandro Lozano, María Del Pilar Bovina Martijena, Maximiliano Ramirez, Marina F Ponzio, Yanina V Berardi, Ana G Sosa, Eugenia Cóncari
BACKGROUND: Nasal cytology in a easy-to apply method to differentiate rhinitis phenotypes from a physiopathogenic and diagnostic perspective. There are controversies about the relationship between clinical severity of rhinitis and inflammatory patterns expressed in the nasal cytology. OBJECTIVES: To study the characteristic of the eosinophil and neutrophil patterns in the nasal scraping for Allergic Rhinitis (AR) and Non Allergic Rhinitis (NAR) and its relationship with the clinical grades of rhinitis established by the Allergic Rhinitis and its Impact on Asthama Guideline (ARIA) Methods: In a observational, cross-sectional study we included patients aged 5 to 18 years presenting symptoms of either allergic (AR) or non- allergic rinitis (NAR) without asthma...
2017: Revista de la Facultad de Ciencias Médicas
https://www.readbyqxmd.com/read/28587510/effects-of-fluticasone-furoate-nasal-spray-on-parameters-of-eosinophilic-inflammation-in-patients-with-nasal-polyposis-and-perennial-allergic-rhinitis
#15
Cveta Špadijer Mirković, Aleksandar Perić, Biserka Vukomanović Đurđević, Danilo Vojvodić
OBJECTIVES: Regulated on activation normal T cell expressed and secreted (RANTES) and eotaxin-2 have been postulated to be responsible for eosinophilia in chronically inflamed nasal mucosa. This study evaluated mucosal production of RANTES and eotaxin-2 in patients with perennial allergic rhinitis (PAR) and nonallergic and allergic form of chronic rhinosinusitis with nasal polyps (CRSwNP) before and after nasal corticosteroid treatment. METHODS: Twenty patients with PAR, 20 nonallergic and 20 allergic CRSwNP patients, and 20 healthy controls were included...
August 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28557568/a-grid-based-nucleus-counting-method-for-estimates-of-the-density-of-superficial-conjunctival-cells-from-impression-cytology-samples-taken-from-normal-healthy-human-eyes
#16
Michael J Doughty
PURPOSE: To develop and validate an easily procured objective estimate of the cell density of the superficial epithelial cells of the normal bulbar conjunctiva using conjunctival impression cytology (CIC). METHODS: From 20 healthy non-contact lens-wearing young adults, CIC was undertaken off the nasal aspect of the exposed bulbar conjunctiva, the filters stained with Giemsa, and images taken at 200× that only included an all-but-contiguous monolayer of epithelial cells...
May 30, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28497672/allergic-and-nonallergic-rhinitis-and-skin-sensitization-to-metals-is-there-a-link
#17
M Gelardi, R Guarino, S Taliente, N Quaranta, A Carpentieri, G Passalacqua
Background. Chromium, Cobalt and Nickel are responsible for contact dermatitis, that is largely prevalent in the general population. They can act also as irritants in the upper and lower respiratory airways. Also rhinitis (allergic and nonallergic) is a high prevalence disorder. Both diseases could share some common inflammatory mechanisms, but the clinical association between skin sensitization to metals and rhinitis was never studied. Objective. We assessed the presence of skin sensitization to metals in subjects with rhinitis...
May 2017: European Annals of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28493047/effects-of-cpap-in-patients-with-obstructive-apnoea-is-the-presence-of-allergic-rhinitis-relevant
#18
A Cisternas, F Aguilar, J M Montserrat, M Àvila, M Torres, A Iranzo, J Berenguer, I Vilaseca
PURPOSE: The aim of the study is to compare the effects of continuous positive airway pressure (CPAP) on the nasal cavities of patients with obstructive sleep apnoea (OSA) and with or without allergic rhinitis (AR/nonAR). METHODS: This paper is a prospective, longitudinal study. Thirty-four consecutive CPAP treatment-adherent patients with OSA (17 AR and 17 nonAR) were evaluated before and 2 months after treatment, by means of clinical (otorhinolaryngological symptoms, daytime sleepiness, overall and rhinoconjunctivitis-specific quality of life), anatomical (otorhinolaryngological examination), functional (auditory function, tubal function, nasal airflow, and mucociliary clearance), and biological variables (nasal cytology)...
May 10, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28492610/nasal-cytology-in-children-scraping-or-swabbing
#19
C Pipolo, S Bianchini, S Barberi, M Landi, E D'Auria, E Fuccillo, M Gaffuri, P Marchisio, C Rosazza, A M Saibene, M Gelardi, S Torretta
Nasal cytology has become a valuable tool in the assessment of a multitude of nasal pathologies in children. Collection methods differ significantly and even though the use of the nasal curette is regarded as the most reliable in adults, most practitioners use the nasal swab in children. However, no studies have validated the reliability and supposed better tolerability of the latter. We have compared these two sampling methods regarding their tolerability and analysed the diagnostic accuracy of the cotton nasal swab (NSW) to identify nasal cytotypes and rhinitis phenotypes, using nasal scraping (NSC) for comparison...
September 1, 2017: Rhinology
https://www.readbyqxmd.com/read/28375041/prevalence-of-external-ear-disorders-in-belgian-stray-cats
#20
Anouck Bollez, Hilde de Rooster, Alessandra Furcas, Sophie Vandenabeele
Objectives Feline otitis externa is a multifactorial dermatological disorder about which very little is known. The objective of this study was to map the prevalence of external ear canal disorders and the pathogens causing otitis externa in stray cats roaming around the region of Ghent, Belgium. Methods One hundred and thirty stray cats were randomly selected during a local trap-neuter-return programme. All cats were European Shorthairs. This study included clinical, otoscopic and cytological evaluation of both external ears of each cat...
April 1, 2017: Journal of Feline Medicine and Surgery
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