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"Carbon Monoxide" AND "Poisoning" AND "Emergency"

J M Moon, B J Chun, S D Lee, M H Shin
This study investigated whether hyperthermia within the first 24 h after presentation was associated with long-term neurological outcomes after acute carbon monoxide (CO) poisoning. This retrospective study included 200 patients with acute severe CO poisoning. Hyperthermia (≥ 37.5°C) developed during the first 24 h after presentation in 55 (27.5%) patients, and poor long-term neurological sequelae assessed at 23 months after acute CO poisoning developed in 19.5% of the patients. The incidence of poor long-term neurological outcomes was significantly higher in the hyperthermia group than in the normothermia group...
December 14, 2018: Human & Experimental Toxicology
Hamza Sunman, Tolga Çimen, Mehmet Erat, Kadriye Gayretli Yayla, Tolga Han Efe, Seda Özkan, Engin Deniz Arslan, Sadık Açıkel
Objectives: Elevated red blood cell distribution width (RDW) is an independent prognostic factor for cardiovascular events that are major causes of mortality in patients with carbon monoxide (CO) poisoning. Due to the limited number of studies, we aimed to investigate the relationship between RDW levels and long-term mortality for these patients. Method: This retrospective study included patients with CO poisoning, who presented to the emergency department. Baseline characteristics, laboratory results and survival status were retrieved from patients' hospital records...
December 2018: Turkish Journal of Emergency Medicine
Shu-Chen Liao, Yan-Chiao Mao, Kun-Ju Yang, Kuo-Cheng Wang, Li-Ying Wu, Chen-Chang Yang
OBJECTIVES: Delayed neuropsychiatric sequelae (DNS) are serious complications of carbon monoxide poisoning; neuropsychiatric disorders can occur within a few days of recovery from acute poisoning. Hyperbaric oxygen therapy (HBOT) has been the main treatment of carbon monoxide (CO) poisoning and was recommended as the treatment choice for CO poisoning by the American Undersea and Hyperbaric Medical Society and the Tenth European Consensus Conference on Hyperbaric Medicine of the European Underwater and Baromedical Society...
November 22, 2018: Journal of the Neurological Sciences
Radek Vančata, Jan Lhotský, Václav Beránek, Josef Krištof, Richard Rokyta
Severe carbon monoxide intoxication may cause tissue injury by hypoxemia and histotoxicity. The affection of the heart muscle often leads to transient global or regional systolic dysfunction of left ventricle or both ventricles and increased occurences of malignant arrhytmias. On the contrary, stress-induced cardiomyopathy is described as temporary segmental loss of contractility, mostly in apical segments of the left ventricle with mid- and basal sparing and less common hypokinesias in mid- or basal parts, or affection of both ventricles...
2018: Vnitr̆ní Lékar̆ství
Shu-Chen Liao, Yan-Chiao Mao, Yao-Min Hung, Ching-Hsing Lee, Chen-Chang Yang
Objective: Delayed neuropsychiatric sequelae (DNS) are serious complications of carbon monoxide (CO) poisoning that adversely affect poisoned patients' quality of life as well as socioeconomic status. This study aimed to determine clinical predictors of DNS in patients with CO poisoning. Methods: This retrospective study included all CO-poisoned patients admitted to the emergency department (ED) of Linkou Chang Gung Memorial Hospital in Taiwan from 1 January 2009 to 31 December 2015...
2018: BioMed Research International
Caner Turan, Eylem Ulas Saz
OBJECTIVE: Children are presented with an unknown intoxication at emergency department (ED) after carbon monoxide (CO) poisoning. Although CO poisoning is well defined in the adult literature, little information exists regarding CO poisoning in childhood, especially in infants. The only diagnostic test for CO poisoning is elevation of the carboxyhemoglobin level in the blood. CASE: We report the second youngest neonate in literature who was severely poisoned by CO and treated with hyperbaric oxygen at the ED...
October 17, 2018: Pediatric Emergency Care
Aleksandra Świderska, Marek Wiśniewski, Marek Wiergowski, Anna Krakowiak, Jacek Sein Anand
BACKGROUND: Poisonings constitute a significant medical, social and economic problem worldwide. In Poland there is no nationwide registry of poisonings, which results in a lack of accurate epidemiological data. Few publications dealing with the problem are based on data obtained from toxicology units and therefore do not include information about cases treated at emergency departments and other non-toxicology units. METHODS: We analyzed all admissions due to poisonings reported to the Polish National Health Fund by all hospital units in Poland in the 2009-2011 period...
October 10, 2018: BMC Pharmacology & Toxicology
Wei-Chih Liao, Wen-Chien Cheng, Biing-Ru Wu, Wei-Chun Chen, Chih-Yu Chen, Chia-Hung Chen, Chih-Yen Tu, Te-Chun Hsia
BACKGROUND: Carbon monoxide (CO), a colorless and odorless gas, is one of the common causes of poisoning-related deaths worldwide. CO poisoning can result in hypoxic brain damage and death, but intensive care can improve the likely outcome for critically ill patients. However, there is a paucity of clinical data regarding the prognostic factors and association between organ dysfunction and clinical outcome of patients treated for CO poisoning in the intensive care unit (ICU). METHODS: We performed a retrospective study of patients admitted to a university affiliated hospital ICU between July 2001 and December 2010 following CO poisoning...
October 5, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
Lihong Zhou, Liming Yuan, Davood Bahrami, Richard A Thomas, James H Rowland
The primary danger with underground mine fires is carbon monoxide poisoning. A good knowledge of smoke and carbon monoxide movement in an underground mine during a fire is of importance for the design of ventilation systems, emergency response, and miners' escape and rescue. Mine fire simulation software packages have been widely used to predict carbon monoxide concentration and its spread in a mine for effective mine fire emergency planning. However, they are not highly recommended to be used to forecast the actual carbon monoxide concentration due to lack of validation studies...
2018: Journal of Fire Sciences
Hyukhoon Kim, Sangchun Choi, Eunjung Park, Eunhui Yoon, Younggi Min, Samsun Lampotang
OBJECTIVE: Reliable biomarkers of delayed neuropsychological sequelae (DNS) after acute carbon monoxide (CO) poisoning are lacking. This study investigated the associations between potential serum markers and the development of DNS after acute CO poisoning. METHODS: Retrospective chart reviews were conducted for patients diagnosed with acute CO poisoning during a 28-month period. The patients were divided into two groups according to the presence or absence of having developed DNS...
September 2018: Clinical and Experimental Emergency Medicine
Abuzer Coşkun, Fatma Ayşen Eren, Şevki Hakan Eren, İlhan Korkmaz
OBJECTIVE: Carbon monoxide (CO) poisoning is very common worldwide. In this study, we aimed to evaluate the predictivity of neuro psychosis in carbon monoxide poisoning by the admission levels of red cell distribution (RDW), mean platelet volume (MPV) and troponin I levels which can be measured quickly and easily in the emergency department (ED). PATIENTS AND METHODS: This single center observational study included a total of 216 consecutive patients who presented to the ED due to CO poisoning between January 2009 and December 2013...
September 15, 2018: American Journal of Emergency Medicine
Marcos Vieira Godinho, Cíntia Elias Pires, Luiz Celso Hygino da Cruz
Our purpose is to describe typical computed tomography and magnetic resonance imaging findings in encephalopathies in the emergency. The focus of this article are the most frequent toxic and acquired metabolic diseases and their preferential sites of involvement, such as hepatic encephalopathy, hypoglicemia, nonketotic hyperglycemia, osmotic demyelination, posterior reversible encephalopathy syndrome, uremia, illegal drug abuse, carbon monoxide poisoning, and hypoxic-ischemic encephalopathy. The radiologist must be able to identify the most usual patterns of lesion in computed tomography and magnetic resonance imaging in these settings...
October 2018: Seminars in Ultrasound, CT, and MR
Craig Nowadly, Kelly Johnson-Arbor, Annelee Boyle
Background: The fetus is uniquely susceptible to carbon monoxide (CO) exposure. We present a case of severe unintentional CO poisoning in the first trimester of pregnancy. Case: A 23-year-old G5P2022 female at 11 weeks' gestational age sat in a car with the engine idling. She was unaware that the vehicle's exhaust pipe was blocked with snow. She was found to be unresponsive, with an initial carboxyhemoglobin (COHb) concentration of 47.1%. She underwent emergent treatment with hyperbaric oxygen therapy...
July 2018: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
Leman Akcan Yildiz, Ayse Gultekingil, Selman Kesici, Benan Bayrakci, Ozlem Teksam
OBJECTIVE: Carbon monoxide (CO) is a gas, which is produced by incomplete combustion of hydrocarbon-containing substances, and causes significant tissue and organ damage in the common event of CO poisoning. This study aims to evaluate the demographic, clinical, and laboratory characteristics of patients diagnosed with CO poisoning in the emergency department and to determine the factors associated with severe course in the acute phase of poisoning. METHODS: A total of 331 patients diagnosed with CO poisoning in Hacettepe University Children's Hospital, Pediatric Emergency Unit, between January 2004 and March 2014 were included in the study...
August 13, 2018: Pediatric Emergency Care
S Sungur, U Bilge, N Acar, I Unluoglu
Objective: We aimed to evaluate demographic, etiological, clinical features, and prognosis of poisoning cases applied to a tertiary emergency department retrospectively. Materials and Methods: The recordings of poisoning cases aged 18 years old and over which applied to the department of emergency medicine between the dates of 2010-2015 were examined. Age, gender, admission date, amount of time passed since exposure to the poisonous substance, application method, cause of poisoning, laboratory findings at arrival, vital signs, type of poisonous substance, the way of taking, treatment method in urgent care, consultation need, and the outcome of cases were recorded...
August 2018: Nigerian Journal of Clinical Practice
Shu-Chen Kuo, Chien-Kang Hsu, Chien-Tsung Tsai, Min-Jung Chieh
Carbon monoxide poisoning is the most commonly seen cause of poisoning in the emergency room (ER). The high affinity between carbon monoxide and hemoglobin and their complex biological characteristics greatly increase the risks of cardiac, nervous, muscular, and kidney diseases. In severe cases, patients may lose consciousness or die in just a few minutes. In recent years, hyperbaric oxygen therapy has been applied extensively in patients with severe conditions such as carbon monoxide poisoning and cerebral hypoxia...
August 2018: Hu Li za Zhi the Journal of Nursing
Alessandro Giuffrè, João B Vicente
Hydrogen sulfide (H2 S) has emerged as a relevant signaling molecule in physiology, taking its seat as a bona fide gasotransmitter akin to nitric oxide (NO) and carbon monoxide (CO). After being merely regarded as a toxic poisonous molecule, it is now recognized that mammalian cells are equipped with sophisticated enzymatic systems for H2 S production and breakdown. The signaling role of H2 S is mainly related to its ability to modify different protein targets, particularly by promoting persulfidation of protein cysteine residues and by interacting with metal centers, mostly hemes...
2018: Oxidative Medicine and Cellular Longevity
Nicolai Nistor, Otilia Elena Frasinariu, Aniela Rugină, Irina Mihaela Ciomaga, Cristina Jităreanu, Violeta Ştreangă
Accidental poisonongs are an important cause of morbidity and even mortality, especially in young children.We performed a retrospective observational study on a group of children admitted at the Regional Center of Toxicology at the Children's Emergency Hospital "St. Mary" Iasi with accidental intoxication within a period of 3 years. Data were collected from patients' files and processed with a SPPS 18.0 database and a 95% confidence interval.During this period, 480 children were admitted with accidental intoxication...
July 2018: Medicine (Baltimore)
Alyssa M Falise, Isabel Griffin, Danielle Fernandez, Xeniamaria Rodriguez, Emily Moore, Anne Barrera, Juan Suarez, Lidice Cutie, Guoyan Zhang
OBJECTIVE: The Florida Department of Health in Miami-Dade County (DOH-Miami-Dade) investigated 106 reported carbon monoxide (CO) exposures over a 9-day timeframe after Hurricane Irma. This report evaluates risk factors for CO poisoning and the importance of heightened surveillance following natural disasters. METHODS: Data on CO poisoning cases from September 9 to 18, 2017 were extracted from Merlin, the Florida Department of Health Surveillance System. Medical records were obtained and follow-up interviews were conducted to collect data on the confirmed CO poisoning cases...
July 17, 2018: Disaster Medicine and Public Health Preparedness
Y Y Han, Y Wang, G Q Zhao, J L Yang, L Wang, W Z Wang
Objective: To investigate the relationship between neutrophil-to-lymphocyte ratio (NLR) and myocardial injury induced by acute carbon monoxide poisoning. Methods: A retrospective analysis was performed on 214 patients with acute carbon monoxide poisoning who were admitted to Emergency Depart-ment of Harrison International Peace Hospital, Hebei Medical University, from 2015 to 2017. According to the diagnostic criteria for toxic heart disease and the level of cardiac troponin I (cTnI), a biomarker of cardiac injury, these patients were divided into myocardial injury group (n = 84) and non-myocardial injury group (n=130)...
May 20, 2018: Chinese Journal of Industrial Hygiene and Occupational Diseases
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