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Fungal sinusitis

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https://www.readbyqxmd.com/read/29150882/plantar-eumycetoma-by-madurella-mycetomatis-in-a-heart-transplanted-patient-living-in-portugal
#1
N Cunha, M L Martins, N Fradinho, P Martins, J Cabete
Eumycetoma is a chronic granulomatous fungal infection of dermal and subcutaneous tissue rarely seen in Europe. It is characterized by a painless subcutaneous mass with drainage of macroscopic grains through sinus tracts,(1,2) spreading with severe tissue destruction, including fascia and bone. This article is protected by copyright. All rights reserved.
November 17, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29144607/eustachian-tube-dysfunction-symptoms-in-patients-treated-in-a-tertiary-rhinology-clinic
#2
Michael J Marino, Lina Chooi Ling, William C Yao, Amber Luong, Martin J Citardi
BACKGROUND: Ear symptoms are common among patients presenting to a rhinology clinic. Validated inventories are available for patient quality-of-life in sinonasal disease and Eustachian tube dysfunction (ETD). This study sought to determine the extent of ETD symptoms, using validated metrics, in a large population of patients presenting to a tertiary rhinology clinic. METHODS: Seven-item Eustachian Tube Dysfunction Questionnaires (ETDQ-7) and 22-item Sino-Nasal Outcome Tests (SNOT-22) were prospectively collected from 492 patients treated in a tertiary rhinology clinic...
November 16, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29125646/epidural-abscess-caused-by-schizophyllum-commune-a-rare-case-of-rhinogenic-cranial-complication-by-a-filamentous-basidiomycete
#3
Kazuya Tone, Ryuichi Fujisaki, Shigehiro Hagiwara, Takashi Tamura, Shinobu Ishigaki, Mohamed Mahdi Alshahni, Makoto Takehisa, Takehiro Watanabe, Takuya Yasui, Takuo Tokairin, Toshiyo Sagawa, Tetsuya Sakamoto, Ken Ito, Kazuyoshi Kuwano, Koichi Makimura
Central nervous system (CNS) infections due to filamentous basidiomycetes are extremely rare. We encountered a case of epidural abscess due to Schizophyllum commune that extended from sinusitis. A 53-year-old Japanese man presented at our hospital with a headache. Computed tomography (CT) of the cranium and sinuses showed ethmoid and sphenoid sinusitis with no intracranial abnormalities. The patient was diagnosed with acute sinusitis and underwent antibiotic treatment. However, the symptoms deteriorated, and the patient came to our hospital again with consciousness disturbance...
November 10, 2017: Mycoses
https://www.readbyqxmd.com/read/29122081/gender-specific-differences-in-serum-immunoglobulin-e-levels-and-prevalence-of-fungus-in-sinonasal-tissue-noted-in-patients-with-chronic-rhinosinusitis-who-underwent-endoscopic-sinus-surgery
#4
Antoine Azar, Matthew A Rank, Matthew A Zarka, Yu-Hui Chang, Devyani Lal
BACKGROUND: We previously presented that women with chronic rhinosinusitis (CRS) who elected endoscopic sinus surgery (ESS) have a higher symptom burden than men. Causes of these gender-based differences warranted further study. OBJECTIVES: To study gender differences in another cohort of adult patients with CRS who underwent ESS and to compare key histopathologic and serologic features Methods: Patients with CRS who underwent ESS (from 2011 to 2014) with structured histopathology reports on surgical samples were studied...
November 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29119669/sinusitis-caused-by-exserohilum-rostratum-after-cord-blood-transplantation-for-myelodysplastic-syndrome-a-case-report-and-literature-review
#5
Sumiko Kohashi, Takaaki Toyama, Norisato Hashimoto, Masatoshi Sakurai, Jun Kato, Taku Kikuchi, Yuya Koda, Kayoko Sugita, Naoki Hasegawa, Kyoko Yarita, Katsuhiko Kamei, Shinichiro Okamoto, Takehiko Mori
Invasive fungal disease is a serious infectious complication of allogeneic hematopoietic stem cell transplantation (HSCT). Exserohilum rostratum is a species causing phaeohyphomycosis, which rarely causes invasive disease in humans. We treated a case of sinusitis caused by E. rostratum after cord blood transplantation (CBT). A 60-year-old man with myelodysplastic syndrome, who had a medical history of an operation to correct deviation of the nasal septum, developed sinusitis caused by E. rostratum under prolonged profound neutropenia after a second CBT because of the graft rejection of the first transplantation...
November 8, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29106862/an-investigation-of-operative-outcomes-pediatric-invasive-fungal-sinusitis
#6
Curtis Hanba, Peter F Svider, Wanda Lai, Syed Naweed Raza, Anthony Sheyn, Jean Anderson Eloy, Adam J Folbe
OBJECTIVES/HYPOTHESIS: Invasive fungal sinusitis is an uncommon entity among children. Early recognition is crucial for facilitating successful treatment with minimal morbidity. The goal of this analysis was to identify patient characteristics associated with high-risk surgical disease through a population-based examination into this rare and deadly disease process. METHODS: A retrospective chart review of the 2009 and 2012 Kids' Inpatient Database (KID) was conducted...
November 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29101992/acr-appropriateness-criteria-%C3%A2-sinonasal-disease
#7
Claudia F E Kirsch, Julie Bykowski, Joseph M Aulino, Kevin L Berger, Asim F Choudhri, David B Conley, Michael D Luttrull, Diego Nunez, Lubdha M Shah, Aseem Sharma, Vilaas S Shetty, Rathan M Subramaniam, Sophia C Symko, Rebecca S Cornelius
Imaging of sinonasal pathology may occur for assessment of rhinosinusitis or mass lesions. Rhinosinusitis is prevalent in up to 16% of the US population with annual economic burdens estimated at 22 billion dollars. Rhinosinusitis is characterized as acute or chronic based on symptom duration; if four or more episodes occur annually, the term recurrent acute rhinosinusitis (RARS) is used. In acute uncomplicated rhinosinusitis when inflammatory change remains in the paranasal sinuses and nasal cavity, imaging may not be required...
November 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29094017/frequency-and-effect-of-type-1-hypersensitivity-in-patients-from-india-with-chronic-obstructive-pulmonary-disease-and-associated-upper-airways-symptoms
#8
Avi Kumar, Shekhar Kunal, Ashok Shah
Background: Chronic obstructive pulmonary disease (COPD) is now recognized as a systemic disorder with many comorbidities. Atopy in patients with COPD and upper airways symptoms has not been characterized. Objective: We investigated the occurrence and impact of aeroallergen sensitisation in patients with COPD and upper airways symptoms. Methods: All 41 subjects with COPD diagnosed as per Global Initiative for Chronic Obstructive Lung Disease guidelines, underwent spirometry with reversibility, computed tomography of the paranasal sinuses (CT-PNS), skin prick test (SPT) against common aeroallergens and responded to St...
October 2017: Asia Pacific Allergy
https://www.readbyqxmd.com/read/29075960/a-case-of-fungus-ball-type-maxillary-sinusitis-due-to-penicillium-roqueforti
#9
T Radulesco, A Varoquaux, S Ranque, P Dessi, J Michel, C Cassagne
The Penicillium genera, encompassing about 225 different species of fungi, are naturally present in the environment. These genera are poorly linked to human disease, except for Penicillium marneffei causing septicemia in immunocompromised hosts. Thus, Penicillium species recovered from respiratory tract samples are often considered as inhaled contaminants in the clinical laboratory. However, we report here a case of fungal maxillary sinusitis due to Penicillium roqueforti diagnosed in a 40-year-old female, a teacher, complaining of moderate pain for months in the maxillary sinus and chronic posterior rhinorrhea...
October 26, 2017: Mycopathologia
https://www.readbyqxmd.com/read/29051882/osteomyelitis-of-fibula-rare-case-with-various-differential-diagnosis
#10
Ashok Khurana, Sanjay Chhawra, Ravi Gupta, Santosh Kumar
INTRODUCTION: The osteomyelitis of fibula is a rare case to present. Osteomyelitis is clinical diagnosis with support of various investigation with proper surgical technique and various Differential Diagnosis it is treated with good satisfactory result. CASE REPORT: A 65-year-male operated 10 years back for tibial plateau fracture was asymptomatic but for last 3 months started pus discharging sinus from middle third of leg. We investigated and done implant removal with abnormal tissue abnormal bone was excised out, but very unusual presentation intraoperative necrotic massive debris was there like wood pieces mimic as neoplastic lesion, metastasis, fungal osteomyelitis, or granulomatous infection...
May 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29045032/a-retrospective-review-of-six-hundred-and-nineteen-cases-to-determine-the-prevalence-and-factors-associated-with-revision-endoscopic-sinus-surgery-in-afrs-vs-non-afrs-patients
#11
LETTER
A Rajwani, J Manji, A Finkelstein-Kulka, A-R R Habib, S Alsaleh, L Macias-Valle, A R Javer
No abstract text is available yet for this article.
October 17, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29040711/diagnosis-and-outcome-of-biopsies-of-indeterminate-lesions-of-the-cavernous-sinus-and-meckel-s-cave-a-retrospective-case-series-in-85-patients
#12
Joshua D Hughes, Joseph Kapurch, Jamie J Van Gompel, Fredric B Meyer, Bruce E Pollock, John Atkinson, Michael J Link
BACKGROUND: When clinical presentation, laboratory studies, or imaging cannot diagnose cavernous sinus (CS) and/or Meckel's cave (MC) lesions, biopsy may be necessary. OBJECTIVE: To review our institutional series of biopsies of indeterminate CS and MC lesions. METHODS: Records from January 1994 to June 2016 were searched for biopsied indeterminate CS and MC lesions. We defined indeterminate as having an atypical imaging appearance or a broad differential and the need for tissue for definitive diagnosis...
October 11, 2017: Neurosurgery
https://www.readbyqxmd.com/read/29026931/imaging-patterns-of-rhino-orbital-cerebral-mucormycosis-in-immunocompromised-patients-when-to-suspect-complicated-mucormycosis
#13
Peter Raab, Ludwig Sedlacek, Stefanie Buchholz, Stefan Stolle, H Lanfermann
PURPOSE: The aim of this study was to describe radiological imaging findings of a complicated sinusitis, which should raise the suspicion of rhino-orbital-cerebral mucormycosis as being the underlying cause. METHODS: In this retrospective analysis, we describe the cases and imaging findings of 8 patients with proven mucormycosis. These patients presented mostly with new facial or orbital swelling and were referred for imaging to our institution. Magnetic resonance imaging and computed tomography images were classified as abnormal or normal with respect to orbital, paranasal and cerebral signal results...
October 12, 2017: Clinical Neuroradiology
https://www.readbyqxmd.com/read/29026829/aggressive-combined-medical-and-surgical-management-of-mucormycosis-results-in-disease-eradication-in-2-pediatric-patients
#14
Haley F M Augustine, Colin White, James Bain
Rhinocerebral mucormycosis is an acute, rapidly fatal, fungal infection, classically involving the nasal mucosa and paranasal sinuses. It is an aggressive, opportunistic infection that frequently progresses to involve the orbit and cerebrum. Cerebral extension in immunocompromised patients is almost universally fatal. There are limited data on mucormycosis in pediatric immunocompromised patients in the literature, with only few reports on rhinocerebral involvement. The immunocompromised patients described in this report presented with suspected periorbital and nasal cellulitis, progressing rapidly to necrotic changes in nasal tissue and oral palatal mucosa...
August 2017: Plastic Surgery
https://www.readbyqxmd.com/read/29024448/isolated-sphenoid-sinus-opacifications-a-systematic-review-and-meta-analysis
#15
REVIEW
William J Moss, Andrey Finegersh, Aria Jafari, Bharat Panuganti, Charles S Coffey, Adam DeConde, Jacob Husseman
BACKGROUND: Isolated sphenoid sinus opacifications (ISSOs) represent a relatively uncommon disease with the potential for serious complications. To better understand this disease, we performed a systematic review to further characterize the underlying pathologies, associated symptoms, and treatment outcomes of patients with ISSOs. METHODS: A systematic review of ISSO case series was performed utilizing the Medline, Embase, Web of Science, and Cochrane databases in accordance with guidelines established by PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses)...
October 12, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28972988/orbital-complications-of-paranasal-sinusitis-in-taiwan-1988-through-2015-acute-ophthalmological-manifestations-diagnosis-and-management
#16
Yi-Sheng Chang, Po-Lin Chen, Jia-Horung Hung, Hsiao-Yen Chen, Chun-Chieh Lai, Chun-Yen Ou, Chia-Ming Chang, Chien-Kuo Wang, Hon-Chun Cheng, Sung-Huei Tseng
PURPOSE: Paranasal sinusitis is widespread and can lead to orbital complications, blindness, and death. However, the correlation between ophthalmological findings and disease staging remains unclear. This study aimed to investigate the staging, acute ophthalmological manifestations, diagnosis, management, and outcomes of orbital complications of paranasal sinusitis during a 27-year period. METHODS: We retrospectively reviewed the medical records of all patients with orbital complications of paranasal sinusitis hospitalized at the National Cheng Kung University Hospital, a medical center in Taiwan during 1988-2015...
2017: PloS One
https://www.readbyqxmd.com/read/28968675/pharmacodynamics-of-the-novel-antifungal-agent-f901318-for-acute-sinopulmonary-aspergillosis-caused-by-aspergillus-flavus
#17
Clara E Negri, Adam Johnson, Laura McEntee, Helen Box, Sarah Whalley, Julie A Schwartz, V Ramos-Martín, Joanne Livermore, Ruwanthi Kolamunnage-Dona, Arnaldo L Colombo, William W Hope
Background: Aspergillus flavus is one of the most common agents of invasive aspergillosis and is associated with high mortality. The orotomides are a new class of antifungal agents with a novel mechanism of action. An understanding of the pharmacodynamics of the lead compound F901318 is required to plan safe and effective regimens for clinical use. Methods: The pharmacokinetics (PK) and pharmacodynamics (PD) of F901318 were evaluated by developing new in vitro and in vivo models of invasive fungal sinusitis...
September 12, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28959795/comparison-of-serum-pcr-assay-and-histopathology-for-the-diagnosis-of-invasive-aspergillosis-and-mucormycosis-in-immunocompromised-patients-with-sinus-involvement
#18
S Shokouhi, J Mirzaei, M M Sajadi, A Javadi
BACKGROUND AND PURPOSE: Invasive fungal infections cause morbidity and mortality in patients with hematologic malignancies and immunosuppression. Although these infections are commonly caused by Candida and Aspergillus species, infections caused by Mucoralean fungi are also on a growing trend. The definitive diagnosis of mucormycosis includes visualization of non-septate hyphae on pathology or growth of Mucoralean fungi culture. Polymerase chain reaction (PCR) is used to diagnose mucormycosis from paraffin blocks; however, it yields discrepant results in diagnosis of mucormycosis from blood samples...
December 2016: Advances in Medical Mycology (Iran)
https://www.readbyqxmd.com/read/28953151/bony-changes-in-a-unilateral-maxillary-sinus-fungal-ball
#19
Young Joon Jun, Jae Min Shin, Jae Yong Lee, Byoung Joon Baek
OBJECTIVES: In the paranasal sinus fungal ball (SFB), changes that occur in the underlying bone have not been well described. Recently, bacterial coinfection has been reported in patients with paranasal SFB. We evaluated whether bone changes occur in patients with unilateral maxillary SFB, and also how bacteria in an SFB affect the bony wall of the sinus. METHODS: A retrospective study of patients with a unilateral maxillary SFB undergoing endoscopic sinus surgery was conducted from July 2009 to December 2015...
September 25, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28931197/study-of-factors-responsible-for-recidivism-in-allergic-fungal-rhinosinusitis
#20
Bipin Kishore Prasad
Patients with allergic fungal rhinosinusitis (AFRS) are typically atopic and immunocompetent. Despite combined modality treatment based on surgery and immunomodulation, the potential for recidivism is well recognized. A study was conducted in a military hospital in India to identify the factors responsible for recidivism in AFRS and to suggest measures to overcome it. Sixty patients with AFRS (42 new cases and 18 cases that required revision surgery) were managed between January 2009 and July 2013. Patients underwent endoscopic, radiologic, and laboratory evaluation for AFRS followed by functional endoscopic sinus surgery...
September 2017: Ear, Nose, & Throat Journal
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