Igor José Dos Santos Nascimento, Paulo Fernando da Silva Santos-Júnior, João Xavier de Araújo-Júnior, Edeildo Ferreira da Silva-Júnior
Ebola virus (EBOV) is an infectious disease that mainly affects the cardiovascular system. It belongs to the Filoviridae family, consisting of filamentous envelopes, non-segmented negative RNA genome. EBOV was initially identified in Sudan and Zaire (now named the Democratic Republic of Congo), around 1967. It is transmitted mainly by contact with secretions (blood, sweat, saliva, and tears) from infected wild animals, such as non-human primates and bats. It has gained more prominence in recent years, due to the recent EBOV outbreaks that occurred from 2013 to 2016, resulting in approximately 28,000 infected individuals, with a mortality rate of 40-70%, affecting mainly Liberia, Guinea, and Sierra Leone...
April 4, 2022: Mini Reviews in Medicinal Chemistry